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ONTOLOGY REPORT - ANNOTATIONS


Term:transcription preinitiation complex assembly
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Accession:GO:0070897 term browser browse the term
Definition:The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription.
Synonyms:exact_synonym: DNA-dependent transcriptional preinitiation complex assembly;   DNA-templated transcriptional preinitiation complex assembly
 broad_synonym: transcription PIC biosynthesis;   transcription PIC formation;   transcriptional preinitiation complex formation


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transcription preinitiation complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gtf2b general transcription factor IIB JBrowse link 2 248,709,433 248,727,741 RGD:1600115
negative regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Thra thyroid hormone receptor alpha JBrowse link 10 86,657,285 86,684,935 RGD:1600115
RGD:1624291
positive regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:1624291
G Cand1 cullin-associated and neddylation-dissociated 1 JBrowse link 7 62,124,362 62,162,451 RGD:8553447
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:1625706
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1600115
RGD:1624291
G Ikzf1 IKAROS family zinc finger 1 JBrowse link 14 91,782,281 91,867,828 RGD:1624291
G Psmc2 proteasome 26S subunit, ATPase 2 JBrowse link 4 9,867,132 9,881,383 RGD:13792537
G Psmc3 proteasome 26S subunit, ATPase 3 JBrowse link 3 79,876,938 79,882,319 RGD:13792537
G Psmc4 proteasome 26S subunit, ATPase 4 JBrowse link 1 84,978,220 84,986,536 RGD:13792537
G Psmc5 proteasome 26S subunit, ATPase 5 JBrowse link 10 94,445,877 94,451,811 RGD:13792537
G Psmc6 proteasome 26S subunit, ATPase 6 JBrowse link 15 19,667,453 19,688,916 RGD:13792537
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
G Wnt10b Wnt family member 10B JBrowse link 7 140,448,284 140,466,159 RGD:1624291
regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf7ip activating transcription factor 7 interacting protein JBrowse link 4 170,476,998 170,563,063 RGD:1624291
G Dr1 down-regulator of transcription 1 JBrowse link 14 2,463,651 2,475,004 RGD:13792537
G LOC100910207 protein Dr1-like JBrowse link 14 1,621,021 1,632,432 RGD:13792537
RNA polymerase I preinitiation complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Baz2a bromodomain adjacent to zinc finger domain, 2A JBrowse link 7 2,518,267 2,548,840 RGD:1600115
G LOC103694876 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 RGD:1600115
G Pih1d1 PIH1 domain containing 1 JBrowse link 1 101,151,240 101,156,806 RGD:1600115
G Polr1e RNA polymerase I subunit E JBrowse link 5 60,572,573 60,588,097 RGD:1624291
RGD:13792537
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor JBrowse link 10 3,170,387 3,214,648 RGD:1600115
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 JBrowse link 8 22,648,323 22,739,468 RGD:1600115
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 JBrowse link 20 13,679,955 13,702,821 RGD:1600115
G Taf1b TATA-box binding protein associated factor, RNA polymerase I subunit B JBrowse link 6 43,644,931 43,722,124 RGD:1600115
RGD:1624291
G Taf1c TATA-box binding protein associated factor, RNA polymerase 1 subunit C JBrowse link 19 52,246,061 52,252,642 RGD:1600115
G Ubtf upstream binding transcription factor JBrowse link 10 90,250,275 90,265,772 RGD:1600115
RNA polymerase II preinitiation complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brf2 BRF2, RNA polymerase III transcription initiation factor subunit JBrowse link 16 69,089,955 69,094,678 RGD:13792537
G Gtf2a2 general transcription factor 2A subunit 2 JBrowse link 8 76,422,341 76,435,587 RGD:1624291
RGD:13792537
G Gtf2b general transcription factor IIB JBrowse link 2 248,709,433 248,727,741 RGD:1600115
RGD:13792537
RGD:1624291
G Gtf2f2 general transcription factor IIF subunit 2 JBrowse link 15 57,942,057 58,068,892 RGD:9681417
G LOC103695118 transcription initiation factor IIA subunit 2 RGD:13792537
G Med6 mediator complex subunit 6 JBrowse link 6 105,302,558 105,316,024 RGD:13792537
G Taf11 TATA-box binding protein associated factor 11 JBrowse link 20 7,476,648 7,484,417 RGD:13792537
G Taf12 TATA-box binding protein associated factor 12 JBrowse link 5 150,459,701 150,476,521 RGD:13792537
G Taf6 TATA-box binding protein associated factor 6 JBrowse link 12 19,320,269 19,328,706 RGD:13792537
G Taf7 TATA-box binding protein associated factor 7 JBrowse link 18 30,779,149 30,781,297 RGD:13792537
G Taf7l TATA-box binding protein associated factor 7-like JBrowse link X 105,292,338 105,308,554 RGD:13792537
G Taf7l-ps1 TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, pseudogene 1 JBrowse link 7 59,138,768 59,139,910 RGD:13792537
G Taf7l2 Taf7l2 RGD:13792537
G Tbp TATA box binding protein JBrowse link 1 57,491,381 57,509,335 RGD:1624291
RNA polymerase III preinitiation complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdp1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB JBrowse link 2 30,248,458 30,340,211 RGD:13792537
G Brf1 BRF1, RNA polymerase III transcription initiation factor subunit JBrowse link 6 137,762,230 137,808,573 RGD:13792537
G Tbp TATA box binding protein JBrowse link 1 57,491,381 57,509,335 RGD:13792537
G Tbpl1 TATA-box binding protein like 1 JBrowse link 1 23,977,154 24,002,512 RGD:13792537
G Tbpl2 TATA box binding protein-like 2 JBrowse link 3 1,095,883 1,116,677 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      organic substance metabolic process 11494
        macromolecule metabolic process 9943
          gene expression 6164
            transcription, DNA-templated 3302
              DNA-templated transcription, initiation 125
                transcription preinitiation complex assembly 45
                  RNA polymerase I preinitiation complex assembly 10
                  RNA polymerase II preinitiation complex assembly + 31
                  RNA polymerase III preinitiation complex assembly 5
                  bacterial-type RNA polymerase preinitiation complex assembly 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      cellular metabolic process 10917
        cellular aromatic compound metabolic process 5567
          nucleobase-containing compound metabolic process 5344
            nucleic acid metabolic process 4850
              RNA metabolic process 4347
                RNA biosynthetic process 3361
                  nucleic acid-templated transcription 3349
                    transcription, DNA-templated 3302
                      DNA-templated transcription, initiation 125
                        transcription preinitiation complex assembly 45
                          RNA polymerase I preinitiation complex assembly 10
                          RNA polymerase II preinitiation complex assembly + 31
                          RNA polymerase III preinitiation complex assembly 5
                          bacterial-type RNA polymerase preinitiation complex assembly 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.