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ONTOLOGY REPORT - ANNOTATIONS


Term:protein K11-linked ubiquitination
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Accession:GO:0070979 term browser browse the term
Definition:A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.


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protein K11-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc1 anaphase promoting complex subunit 1 ISO
IBA
(PMID:18485873)
PMID:21873635
RGD PMID:18485873, PMID:21873635 RGD:13792537 NCBI chr 3:121,147,484...121,226,125
Ensembl chr 3:121,147,547...121,226,125
JBrowse link
G Anapc10 anaphase promoting complex subunit 10 ISO
IBA
(PMID:18485873)
PMID:21873635
RGD PMID:18485873, PMID:21873635 RGD:13792537 NCBI chr19:31,814,686...31,867,928
Ensembl chr19:31,815,319...31,867,850
JBrowse link
G Anapc11 anaphase promoting complex subunit 11 ISO (PMID:18485873) RGD PMID:18485873 NCBI chr10:109,774,779...109,785,877
Ensembl chr10:109,774,878...109,785,877
JBrowse link
G Anapc13 anaphase promoting complex subunit 13 ISO
IBA
(PMID:18485873)
PMID:21873635
RGD PMID:18485873, PMID:21873635 RGD:13792537 NCBI chr 8:111,107,358...111,115,774
Ensembl chr 8:111,107,358...111,115,774
JBrowse link
G Anapc2 anaphase promoting complex subunit 2 ISO (PMID:18485873) RGD PMID:18485873 NCBI chr 3:2,490,496...2,502,247
Ensembl chr 3:2,490,518...2,502,248
JBrowse link
G Anapc4 anaphase promoting complex subunit 4 ISO
IBA
(PMID:18485873)
PMID:21873635
RGD PMID:18485873, PMID:21873635 RGD:13792537 NCBI chr14:60,471,962...60,503,803
Ensembl chr14:60,471,962...60,503,803
JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:18485873)
Ensembl
UniProt
RGD
PMID:18485873, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr12:39,209,134...39,242,696
Ensembl chr12:39,209,129...39,242,690
JBrowse link
G Anapc7 anaphase promoting complex subunit 7 ISO (PMID:18485873) RGD PMID:18485873 NCBI chr12:39,613,898...39,641,999
Ensembl chr12:39,614,733...39,641,285
JBrowse link
G Cdc16 cell division cycle 16 ISO (PMID:18485873) RGD PMID:18485873 NCBI chr16:81,493,355...81,516,493
Ensembl chr16:81,493,355...81,516,493
JBrowse link
G Cdc23 cell division cycle 23 ISO (PMID:18485873) RGD PMID:18485873 NCBI chr18:27,430,924...27,452,569
Ensembl chr18:27,430,905...27,452,420
JBrowse link
G Cdc26 cell division cycle 26 ISO
IBA
ISS
(PMID:18485873)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:18485873, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:78,252,168...78,267,137
Ensembl chr 5:78,253,397...78,267,063
JBrowse link
G Cdc27 cell division cycle 27 ISO
ISS
(PMID:18485873)
GO_REF:0000024
RGD
UniProt
PMID:18485873 GO_REF:0000024 NCBI chr10:92,551,754...92,602,214
Ensembl chr10:92,554,081...92,602,082
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO
ISS
(PMID:25621951)
GO_REF:0000024
RGD
UniProt
PMID:25621951 GO_REF:0000024 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Rnf26 ring finger protein 26 ISO (PMID:25254379) RGD PMID:25254379 NCBI chr 8:48,447,113...48,449,311
Ensembl chr 8:48,447,113...48,449,311
JBrowse link
G Rnf4 ring finger protein 4 IDA PMID:18408734 UniProt PMID:18408734 RGD:8553731 NCBI chr14:81,658,400...81,679,756
Ensembl chr14:81,660,354...81,679,082
JBrowse link
G Ube2a ubiquitin-conjugating enzyme E2A ISO (PMID:20061386) RGD PMID:20061386 NCBI chr  X:123,486,988...123,497,726
Ensembl chr  X:123,486,989...123,497,726
JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B ISO
ISS
(PMID:20061386)
GO_REF:0000024
RGD
UniProt
PMID:20061386 GO_REF:0000024 NCBI chr10:37,439,947...37,454,867
Ensembl chr10:37,441,284...37,455,022
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C ISO (PMID:18485873), (PMID:19822757), (PMID:20061386) RGD PMID:18485873, PMID:19822757, PMID:20061386 NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
JBrowse link
G Ube2d2 ubiquitin-conjugating enzyme E2D 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:28,561,957...28,603,335
Ensembl chr18:28,594,892...28,603,335
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 ISO
ISS
(PMID:20061386)
GO_REF:0000024
RGD
UniProt
PMID:20061386 GO_REF:0000024 NCBI chr 2:240,626,198...240,655,874
Ensembl chr 2:240,627,436...240,655,246
JBrowse link
G Ube2d4 ubiquitin-conjugating enzyme E2D 4 (putative) ISO
IBA
(PMID:20061386)
PMID:21873635
RGD PMID:20061386, PMID:21873635 RGD:13792537 NCBI chr14:2,933,097...2,934,571
Ensembl chr14:2,933,100...2,934,571
JBrowse link
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 ISO
IBA
(PMID:20061386)
PMID:21873635
RGD PMID:20061386, PMID:21873635 RGD:13792537 NCBI chr15:7,402,210...7,928,320
Ensembl chr15:7,871,497...7,927,939
JBrowse link
G Ube2e3 ubiquitin-conjugating enzyme E2E 3 ISO
IBA
(PMID:20061386)
PMID:21873635
RGD PMID:20061386, PMID:21873635 RGD:13792537 NCBI chr 3:65,815,076...65,876,256
Ensembl chr 3:65,815,080...65,871,363
JBrowse link
G Ube2h ubiquitin-conjugating enzyme E2H ISO (PMID:20061386) RGD PMID:20061386 NCBI chr 4:57,511,418...57,625,147
Ensembl chr 4:57,511,418...57,625,257
JBrowse link
G Ube2l3 ubiquitin-conjugating enzyme E2L 3 ISO (PMID:20061386) RGD PMID:20061386 NCBI chr11:88,047,186...88,088,477
Ensembl chr11:88,047,832...88,088,476
JBrowse link
G Ube2s ubiquitin-conjugating enzyme E2S ISS
ISO
GO_REF:0000024
(PMID:19822757), (PMID:20061386), (PMID:20622874), (PMID:21376237)
UniProt
RGD
PMID:19822757, PMID:20061386, PMID:20622874, PMID:21376237 GO_REF:0000024 NCBI chr 1:72,580,424...72,584,484
Ensembl chr 1:72,580,424...72,584,482
JBrowse link
G Ube2t ubiquitin-conjugating enzyme E2T ISO (PMID:20061386) RGD PMID:20061386 NCBI chr13:51,790,877...51,801,379
Ensembl chr13:51,795,867...51,801,163
JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W ISO (PMID:20061386) RGD PMID:20061386 NCBI chr 5:29,798,845...29,812,777 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      cellular metabolic process 11073
        cellular macromolecule metabolic process 8548
          cellular protein metabolic process 5564
            cellular protein modification process 3948
              protein modification by small protein conjugation or removal 951
                protein modification by small protein conjugation 815
                  protein ubiquitination 766
                    protein polyubiquitination 241
                      protein K11-linked ubiquitination 28
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      organic substance metabolic process 11643
        macromolecule metabolic process 10077
          protein metabolic process 6221
            protein modification process 3948
              cellular protein modification process 3948
                protein modification by small protein conjugation or removal 951
                  protein modification by small protein conjugation 815
                    protein ubiquitination 766
                      protein polyubiquitination 241
                        protein K11-linked ubiquitination 28
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.