ONTOLOGY REPORT - ANNOTATIONS


Term:demethylation
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Accession:GO:0070988 term browser browse the term
Definition:The process of removing one or more methyl groups from a molecule.


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demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:1600115
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:1600115
G Mmachc metabolism of cobalamin associated C JBrowse link 5 135,555,587 135,561,723 RGD:1624291
RGD:1600115
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:4889812
DNA demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aicda activation-induced cytidine deaminase JBrowse link 4 155,359,909 155,371,104 RGD:1624291
RGD:13792537
G Alkbh1 alkB homolog 1, histone H2A dioxygenase JBrowse link 6 111,456,096 111,476,829 RGD:1624291
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:1624291
RGD:1600115
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 JBrowse link 4 155,386,367 155,414,034 RGD:1624291
RGD:13792537
RGD:1600115
G Apobec2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 JBrowse link 9 14,529,218 14,542,731 RGD:1624291
RGD:13792537
G Apobec3 apolipoprotein B mRNA editing enzyme catalytic subunit 3 JBrowse link 7 121,108,108 121,128,346 RGD:13792537
G Fto FTO, alpha-ketoglutarate dependent dioxygenase JBrowse link 19 16,774,549 17,115,098 RGD:1624291
G Tdg thymine-DNA glycosylase JBrowse link 7 27,194,000 27,213,676 RGD:1624291
RGD:1600115
G Tet1 tet methylcytosine dioxygenase 1 JBrowse link 20 27,359,122 27,438,039 RGD:1624291
RGD:13792537
G Tet2 tet methylcytosine dioxygenase 2 JBrowse link 2 238,719,389 238,802,975 RGD:1624291
RGD:13792537
G Tet3 tet methylcytosine dioxygenase 3 JBrowse link 4 115,060,702 115,160,800 RGD:1624291
RGD:13792537
histone demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kdm4a lysine demethylase 4A JBrowse link 5 136,967,650 137,014,402 RGD:1624291
G Kdm6b lysine demethylase 6B JBrowse link 10 56,000,494 56,009,582 RGD:1624291
histone H3-K27 demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kdm6a lysine demethylase 6A JBrowse link X 4,805,493 4,945,788 RGD:1624291
RGD:1600115
G Kdm6b lysine demethylase 6B JBrowse link 10 56,000,494 56,009,582 RGD:1624291
RGD:1600115
G Kdm7a lysine demethylase 7A JBrowse link 4 66,915,603 66,957,971 RGD:1624291
G Pagr1 Paxip1-associated glutamate-rich protein 1 JBrowse link 1 198,448,790 198,451,078 RGD:1624291
G Phf8 PHD finger protein 8 JBrowse link X 21,063,487 21,168,750 RGD:1624291
histone H3-K36 demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kdm2a lysine demethylase 2A JBrowse link 1 219,566,130 219,642,294 RGD:1624291
RGD:1600115
G Kdm2b lysine demethylase 2B JBrowse link 12 39,021,924 39,161,954 RGD:1624291
RGD:1600115
G Kdm4a lysine demethylase 4A JBrowse link 5 136,967,650 137,014,402 RGD:1624291
RGD:1600115
G Kdm4b lysine demethylase 4B JBrowse link 9 10,656,035 10,734,127 RGD:1624291
RGD:1600115
G Kdm4c lysine demethylase 4C JBrowse link 5 90,800,139 91,012,662 RGD:1624291
RGD:1600115
G Kdm7a lysine demethylase 7A JBrowse link 4 66,915,603 66,957,971 RGD:1624291
G Kdm8 lysine demethylase 8 JBrowse link 1 196,838,460 196,854,192 RGD:1600115
RGD:13792537
RGD:1624291
G Phf8 PHD finger protein 8 JBrowse link X 21,063,487 21,168,750 RGD:1624291
G Riox1 ribosomal oxygenase 1 JBrowse link 6 107,428,508 107,431,126 RGD:1624291
RGD:1600115
histone H3-K4 demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kdm1a lysine demethylase 1A JBrowse link 5 154,909,003 154,965,171 RGD:9588312
RGD:1624291
RGD:9588315
G Kdm1b lysine demethylase 1B JBrowse link 17 17,987,972 18,028,808 RGD:1624291
RGD:1600115
G Kdm5a lysine demethylase 5A JBrowse link 4 152,892,388 152,972,196 RGD:9588526
RGD:1624291
G Kdm5b lysine demethylase 5B JBrowse link 13 51,384,371 51,455,392 RGD:1624291
G Kdm5c lysine demethylase 5C JBrowse link X 22,302,664 22,349,298 RGD:1624291
G Kdm5d lysine demethylase 5D JBrowse link Y 501,058 589,267 RGD:1624291
G Riox1 ribosomal oxygenase 1 JBrowse link 6 107,428,508 107,431,126 RGD:1624291
RGD:1600115
histone H3-K4 demethylation, trimethyl-H3-K4-specific term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jarid2 jumonji and AT-rich interaction domain containing 2 JBrowse link 17 20,183,440 20,365,219 RGD:1600115
G Kdm5a lysine demethylase 5A JBrowse link 4 152,892,388 152,972,196 RGD:1600115
G Kdm5b lysine demethylase 5B JBrowse link 13 51,384,371 51,455,392 RGD:1600115
G Kdm5d lysine demethylase 5D JBrowse link Y 501,058 589,267 RGD:1600115
histone H3-K9 demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hr HR, lysine demethylase and nuclear receptor corepressor JBrowse link 15 52,241,801 52,261,276 RGD:13792537
G Hsf4 heat shock transcription factor 4 JBrowse link 19 37,225,800 37,232,048 RGD:1624291
RGD:1600115
G Jmjd1c jumonji domain containing 1C JBrowse link 20 22,751,743 22,914,080 RGD:13792537
G Kdm1a lysine demethylase 1A JBrowse link 5 154,909,003 154,965,171 RGD:1624291
RGD:1600115
G Kdm3a lysine demethylase 3A JBrowse link 4 99,503,160 99,547,315 RGD:1624291
RGD:13792537
RGD:1600115
G Kdm3b lysine demethylase 3B JBrowse link 18 27,593,823 27,631,129 RGD:13792537
G Kdm4a lysine demethylase 4A JBrowse link 5 136,967,650 137,014,402 RGD:1624291
RGD:1600115
G Kdm4b lysine demethylase 4B JBrowse link 9 10,656,035 10,734,127 RGD:1624291
RGD:1600115
G Kdm4c lysine demethylase 4C JBrowse link 5 90,800,139 91,012,662 RGD:1624291
RGD:1600115
G Kdm4d lysine demethylase 4D JBrowse link 8 12,968,192 12,993,651 RGD:1624291
RGD:1600115
G Kdm5a lysine demethylase 5A JBrowse link 4 152,892,388 152,972,196 RGD:1624291
G Kdm7a lysine demethylase 7A JBrowse link 4 66,915,603 66,957,971 RGD:1624291
G LOC108348070 lysine-specific demethylase 4D JBrowse link 8 13,511,349 13,513,661 RGD:1600115
G Phf2 PHD finger protein 2 JBrowse link 17 16,240,458 16,274,626 RGD:1624291
RGD:1600115
G Phf8 PHD finger protein 8 JBrowse link X 21,063,487 21,168,750 RGD:1624291
histone H3-R2 demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase JBrowse link 10 105,781,752 105,787,803 RGD:1624291
RGD:1600115
histone H4-K20 demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kdm7a lysine demethylase 7A JBrowse link 4 66,915,603 66,957,971 RGD:1624291
G Phf8 PHD finger protein 8 JBrowse link X 21,063,487 21,168,750 RGD:1624291
histone H4-R3 demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase JBrowse link 10 105,781,752 105,787,803 RGD:1600115
RGD:1624291
histone lysine demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ube2b ubiquitin-conjugating enzyme E2B JBrowse link 10 37,439,947 37,454,867 RGD:1624291
negative regulation of DNA demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dppa3 developmental pluripotency-associated 3 JBrowse link 4 155,437,675 155,441,059 RGD:1600115
RGD:13792537
RGD:1624291
G Dppa3l1 developmental pluripotency associated 3-like 1 JBrowse link 8 60,683,180 60,683,658 RGD:13792537
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
RGD:1600115
G Trim28 tripartite motif-containing 28 JBrowse link 1 65,544,369 65,551,043 RGD:1624291
RGD:1600115
oxidative demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alkbh1 alkB homolog 1, histone H2A dioxygenase JBrowse link 6 111,456,096 111,476,829 RGD:1624291
G Alkbh4 alkB homolog 4, lysine demethylase JBrowse link 12 23,568,204 23,574,133 RGD:13792537
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:1624291
RGD:1600115
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:1624291
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:1624291
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 JBrowse link 12 11,641,500 11,677,818 RGD:5129544
G Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 JBrowse link 12 11,053,888 11,082,742 RGD:5129544
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 JBrowse link 12 18,679,809 18,709,397 RGD:1624291
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:1624291
G Fto FTO, alpha-ketoglutarate dependent dioxygenase JBrowse link 19 16,774,549 17,115,098 RGD:1624291
G Tet1 tet methylcytosine dioxygenase 1 JBrowse link 20 27,359,122 27,438,039 RGD:13792537
G Tet2 tet methylcytosine dioxygenase 2 JBrowse link 2 238,719,389 238,802,975 RGD:13792537
G Tet3 tet methylcytosine dioxygenase 3 JBrowse link 4 115,060,702 115,160,800 RGD:13792537
oxidative DNA demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alkbh1 alkB homolog 1, histone H2A dioxygenase JBrowse link 6 111,456,096 111,476,829 RGD:1600115
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase JBrowse link 12 48,257,575 48,262,244 RGD:1624291
RGD:13792537
oxidative RNA demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase JBrowse link 10 105,781,752 105,787,803 RGD:1600115
RGD:1624291
oxidative single-stranded DNA demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase JBrowse link 3 82,874,242 82,907,467 RGD:1600115
RGD:13792537
RGD:1624291
G Fto FTO, alpha-ketoglutarate dependent dioxygenase JBrowse link 19 16,774,549 17,115,098 RGD:1624291
RGD:1600115
oxidative single-stranded RNA demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase JBrowse link 3 82,874,242 82,907,467 RGD:1624291
RGD:13792537
G Alkbh5 alkB homolog 5, RNA demethylase JBrowse link 10 46,906,314 46,927,759 RGD:1600115
RGD:1624291
RGD:13792537
G Fto FTO, alpha-ketoglutarate dependent dioxygenase JBrowse link 19 16,774,549 17,115,098 RGD:1624291
RGD:1600115
positive regulation of DNA demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Otud4 OTU deubiquitinase 4 JBrowse link 19 31,895,753 31,942,509 RGD:1600115
RGD:1624291
G Stpg4 sperm-tail PG-rich repeat containing 4 JBrowse link 6 11,014,596 11,063,509 RGD:1624291
RGD:1600115
G Usp7 ubiquitin specific peptidase 7 JBrowse link 10 6,930,462 7,019,910 RGD:1600115
RGD:1624291
G Usp9x ubiquitin specific peptidase 9, X-linked JBrowse link X 10,510,033 10,660,555 RGD:1600115
RGD:1624291
protein demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alkbh4 alkB homolog 4, lysine demethylase JBrowse link 12 23,568,204 23,574,133 RGD:1624291
RGD:13792537
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase JBrowse link 10 105,781,752 105,787,803 RGD:1600115
RGD:1624291
G Kdm1a lysine demethylase 1A JBrowse link 5 154,909,003 154,965,171 RGD:1624291
G Phf2 PHD finger protein 2 JBrowse link 17 16,240,458 16,274,626 RGD:1624291
G Ppme1 protein phosphatase methylesterase 1 JBrowse link 1 165,335,242 165,382,216 RGD:1624291
RGD:13792537
tRNA demethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alkbh1 alkB homolog 1, histone H2A dioxygenase JBrowse link 6 111,456,096 111,476,829 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17895
    metabolic process 10649
      demethylation 64
        DNA demethylation + 21
        oxidative demethylation + 17
        protein demethylation + 31
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.