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ONTOLOGY REPORT - ANNOTATIONS


Term:SMAD protein complex
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Accession:GO:0071141 term browser browse the term
Definition:A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven.
Synonyms:exact_synonym: SMAD complex


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SMAD protein complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HMGA2 high mobility group AT-hook 2 JBrowse link 12 65,824,460 65,966,291 RGD:2290271
G SMAD1 SMAD family member 1 JBrowse link 4 145,481,306 145,559,176 RGD:2290271
G SMAD2 SMAD family member 2 JBrowse link 18 47,808,957 47,931,188 RGD:2290271
G SMAD3 SMAD family member 3 JBrowse link 15 67,065,602 67,195,195 RGD:2290271
G SMAD4 SMAD family member 4 JBrowse link 18 51,030,213 51,085,042 RGD:2290271
G SMAD5 SMAD family member 5 JBrowse link 5 136,132,845 136,182,734 RGD:2290271
G SMAD9 SMAD family member 9 JBrowse link 13 36,844,831 36,920,721 RGD:2290271
G SNW1 SNW domain containing 1 JBrowse link 14 77,717,599 77,761,156 RGD:2290271
heteromeric SMAD protein complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SMAD2 SMAD family member 2 JBrowse link 18 47,808,957 47,931,188 RGD:2290271
G SMAD3 SMAD family member 3 JBrowse link 15 67,065,602 67,195,195 RGD:2290271

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  cellular_component 19008
    protein-containing complex 5615
      SMAD protein complex 8
        heteromeric SMAD protein complex 2
        homomeric SMAD protein complex 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.