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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to iron ion
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Accession:GO:0071281 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
Synonyms:exact_synonym: cellular response to iron


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cellular response to iron ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha IEP RGD PMID:23174565, PMID:19679821 RGD:11341702, RGD:11341808 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G B2m beta-2 microglobulin ISO UniProtKB:P02787|UniProtKB:Q07891|UniProtKB:Q30201|UniProtKB:Q9UP52 (PMID:18353247) RGD PMID:18353247 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO (MGI:MGI:4352622|PMID:19252488) RGD PMID:19252488 MGI:MGI:4352622 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Hfe homeostatic iron regulator ISO UniProtKB:P02787|UniProtKB:P61769|UniProtKB:Q07891|UniProtKB:Q9UP52 (PMID:18353247) RGD PMID:18353247 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Slc11a2 solute carrier family 11 member 2 IEP RGD PMID:17663481 RGD:5688717 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Tf transferrin ISO UniProtKB:Q07891|UniProtKB:Q9UP52 (PMID:18353247) RGD PMID:18353247 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tfap2a transcription factor AP-2 alpha ISO
IEA
ISS
(PMID:20808827)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20808827 GO_REF:0000024, GO_REF:0000107 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457
JBrowse link
G Tfr2 transferrin receptor 2 ISO UniProtKB:P02787|UniProtKB:Q07891 (PMID:18353247) RGD PMID:18353247 NCBI chr12:22,177,382...22,194,330
Ensembl chr12:22,177,382...22,194,299
JBrowse link
cellular response to iron(II) ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 IDA PMID:1849823 UniProt PMID:1849823 RGD:8553426 NCBI chr17:42,085,027...42,131,344
Ensembl chr17:42,085,028...42,127,678
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IEP RGD PMID:19608791 RGD:10045561 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
cellular response to iron(III) ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin ISO MGI:MGI:1927183 (MGI:MGI:1203460|PMID:9531620) RGD PMID:9531620 MGI:MGI:1203460 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Ccnb1 cyclin B1 IEP ferric ammonium citrate RGD PMID:18254965 RGD:2316320 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ireb2 iron responsive element binding protein 2 IEP
IDA
RGD PMID:17469137, PMID:16135072 RGD:12904039, RGD:12904046 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
JBrowse link
G Mmp1 matrix metallopeptidase 1 IEP RGD PMID:21683124 RGD:7207286 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP RGD PMID:21683124 RGD:7207286 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to iron term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfya nuclear transcription factor Y subunit alpha IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:14,551,752...14,577,002
Ensembl chr 9:14,551,758...14,576,967
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to iron term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 ISO (MGI:MGI:5527134|PMID:23395172) RGD PMID:23395172 MGI:MGI:5527134 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hrg histidine-rich glycoprotein ISO (MGI:MGI:5527134|PMID:23395172) RGD PMID:23395172 MGI:MGI:5527134 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952
JBrowse link
G Slc40a1 solute carrier family 40 member 1 ISO (MGI:MGI:5527134|PMID:23395172) RGD PMID:23395172 MGI:MGI:5527134 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    response to stimulus 10568
      response to chemical 6330
        response to inorganic substance 818
          response to metal ion 514
            response to iron ion 54
              cellular response to iron ion 18
                cellular response to iron(II) ion 2
                cellular response to iron(III) ion 5
                negative regulation of ferrichrome biosynthetic process in response to iron 0
                regulation of transcription from RNA polymerase II promoter in response to iron + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.