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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to manganese ion
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Accession:GO:0071287 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
Synonyms:exact_synonym: cellular response to manganese


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cellular response to manganese ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A3GALT2 alpha 1,3-galactosyltransferase 2 ISO RGD PMID:1569388 RGD:13831122 NCBI chr 2:68,117,648...68,138,610
Ensembl chr 2:68,118,413...68,138,095
JBrowse link
G APP amyloid beta precursor protein ISO RGD PMID:18583042 RGD:13782134 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
G ATP13A2 ATPase cation transporting 13A2 IEA Ensembl GO_REF:0000107 NCBI chr 2:81,196,355...81,215,736
Ensembl chr 2:81,196,463...81,215,689
JBrowse link
G ATP7B ATPase copper transporting beta ISO RGD PMID:24614235 RGD:11341682 NCBI chr22:162,474...225,599
Ensembl chr22:191,888...225,266
JBrowse link
G BACE1 beta-secretase 1 ISO RGD PMID:18583042 RGD:13782134 NCBI chr 5:16,308,953...16,319,100
Ensembl chr 5:16,308,944...16,319,100
JBrowse link
G CASP12 caspase 12 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 5:27,162,840...27,176,964
Ensembl chr 5:27,161,700...27,177,683
JBrowse link
G DBH dopamine beta-hydroxylase ISO RGD PMID:19276553 RGD:5129515 NCBI chr 9:50,004,806...50,024,130
Ensembl chr 9:50,004,806...50,024,130
JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr10:1,606,693...1,612,410
Ensembl chr10:1,606,693...1,611,303
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 9:11,930,614...12,006,724
Ensembl chr 9:11,934,965...12,006,814
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:19643132 RGD:2325970 NCBI chr 9:48,492,967...48,513,981
Ensembl chr 9:48,493,287...48,509,050
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:19643132 RGD:2325970 NCBI chr 6:32,132,070...32,678,319
Ensembl chr 6:32,303,121...32,668,960
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:19643132 RGD:2325970 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr15:42,456,793...42,474,122
Ensembl chr15:42,456,764...42,579,311
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 9:57,850,870...57,855,607
Ensembl chr 9:57,850,922...57,855,257
JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:16568477, PMID:17469137 RGD:12904039, RGD:12904041 NCBI chr13:38,398,445...38,441,128
Ensembl chr13:38,400,591...38,441,015
JBrowse link
G LRRK2 leucine rich repeat kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870
JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:28232070 RGD:12910738 NCBI chr 2:84,284,719...84,310,715
Ensembl chr 2:84,284,719...84,308,225
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:19781568 RGD:5130971 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764
JBrowse link
G TH tyrosine hydroxylase ISO RGD PMID:19781568 RGD:5130971 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602
JBrowse link
regulation of cellular response to manganese ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC30A10 solute carrier family 30 member 10 ISO (PMID:25319704) UniProtKB PMID:25319704 NCBI chr38:14,705,517...14,746,835
Ensembl chr38:14,709,866...14,747,540
JBrowse link
response to manganese-induced endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr10:25,528,880...25,531,018
Ensembl chr10:25,528,874...25,530,993
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 8:41,354,400...41,371,676
Ensembl chr 8:41,351,244...41,371,056
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16162
    response to stimulus 8537
      response to chemical 5053
        response to inorganic substance 795
          response to metal ion 502
            response to manganese ion 37
              cellular response to manganese ion 23
                negative regulation of cellular response to manganese ion 0
                positive regulation of cellular response to manganese ion 0
                regulation of cellular response to manganese ion + 1
                response to manganese-induced endoplasmic reticulum stress 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.