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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to manganese ion
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Accession:GO:0071287 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
Synonyms:exact_synonym: cellular response to manganese


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cellular response to manganese ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A3GALT2 alpha 1,3-galactosyltransferase 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:33,306,766...33,321,098
Ensembl chr 1:33,306,766...33,321,098
JBrowse link
G APP amyloid beta precursor protein IEA Ensembl GO_REF:0000107 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G ATP13A2 ATPase cation transporting 13A2 IMP
TAS
(PMID:22285144)
(PMID:23628791), (PMID:26392192)
ParkinsonsUK-UCL PMID:22285144, PMID:23628791, PMID:26392192 NCBI chr 1:16,985,958...17,011,972
Ensembl chr 1:16,985,958...17,011,928
JBrowse link
G ATP7B ATPase copper transporting beta ISO RGD PMID:24614235 RGD:11341682 NCBI chr13:51,932,669...52,012,130
Ensembl chr13:51,930,436...52,012,125
JBrowse link
G BACE1 beta-secretase 1 IEA Ensembl GO_REF:0000107 NCBI chr11:117,285,207...117,316,256
Ensembl chr11:117,285,207...117,316,259
JBrowse link
G CASP12 caspase 12 (gene/pseudogene) ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr11:104,885,718...104,898,460
Ensembl chr11:104,885,718...104,898,670
JBrowse link
G DBH dopamine beta-hydroxylase ISO RGD PMID:19276553 RGD:5129515 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr17:64,039,142...64,132,469
Ensembl chr17:64,039,142...64,130,819
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:19643132 RGD:2325970 NCBI chr 9:137,139,092...137,168,759
Ensembl chr 9:137,139,154...137,168,756
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:19643132 RGD:2325970 NCBI chr16:9,753,404...10,182,928
Ensembl chr16:9,753,404...10,182,928
Ensembl chr16:9,753,404...10,182,928
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:19643132 RGD:2325970 NCBI chr12:13,537,337...13,982,012
Ensembl chr12:13,437,942...13,982,002
Ensembl chr12:13,437,942...13,982,002
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,645
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 IEA Ensembl GO_REF:0000107 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:16568477, PMID:17469137 RGD:12904039, RGD:12904041 NCBI chr15:78,437,431...78,501,453
Ensembl chr15:78,437,431...78,501,453
JBrowse link
G LRRK2 leucine rich repeat kinase 2 IMP (PMID:23628791) ParkinsonsUK-UCL PMID:23628791 NCBI chr12:40,224,890...40,369,285
Ensembl chr12:40,196,744...40,369,285
JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:28232070 RGD:12910738 NCBI chr 1:11,980,215...12,013,508
Ensembl chr 1:11,980,181...12,015,211
Ensembl chr 1:11,980,181...12,015,211
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase TAS (PMID:23628791) ParkinsonsUK-UCL PMID:23628791 NCBI chr 6:161,347,417...162,727,802
Ensembl chr 6:161,347,417...162,727,771
Ensembl chr 6:161,347,417...162,727,771
JBrowse link
G SLFN14 schlafen family member 14 ISS UniProtKB GO_REF:0000024 NCBI chr17:35,543,985...35,560,819
Ensembl chr17:35,548,125...35,558,098
Ensembl chr17:35,548,125...35,558,098
JBrowse link
G TH tyrosine hydroxylase IEA Ensembl GO_REF:0000107 NCBI chr11:2,163,929...2,174,081
Ensembl chr11:2,163,929...2,171,877
Ensembl chr11:2,163,929...2,171,877
JBrowse link
regulation of cellular response to manganese ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC30A10 solute carrier family 30 member 10 IDA (PMID:25319704) UniProtKB PMID:25319704 NCBI chr 1:219,910,395...219,959,098
Ensembl chr 1:219,685,427...219,958,647
JBrowse link
response to manganese-induced endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr22:39,514,494...39,522,686
Ensembl chr22:39,519,672...39,522,683
Ensembl chr22:39,519,672...39,522,683
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 IEA Ensembl GO_REF:0000107 NCBI chr 2:88,556,741...88,627,464
Ensembl chr 2:88,556,741...88,627,464
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,151...67,386,516
Ensembl chr14:67,360,151...67,386,516
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18651
    response to stimulus 10131
      response to chemical 5620
        response to inorganic substance 841
          response to metal ion 533
            response to manganese ion 38
              cellular response to manganese ion 24
                negative regulation of cellular response to manganese ion 0
                positive regulation of cellular response to manganese ion 0
                regulation of cellular response to manganese ion + 1
                response to manganese-induced endoplasmic reticulum stress 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.