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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to manganese ion
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Accession:GO:0071287 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
Synonyms:exact_synonym: cellular response to manganese


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cellular response to manganese ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A3GALT2 alpha 1,3-galactosyltransferase 2 ISO RGD PMID:1569388 RGD:13831122 NCBI chr 6:89,557,492...89,562,835
Ensembl chr 6:89,558,423...89,562,490
JBrowse link
G APP amyloid beta precursor protein ISO RGD PMID:18583042 RGD:13782134 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,434,869...189,716,057
JBrowse link
G ATP13A2 ATPase cation transporting 13A2 IEA Ensembl GO_REF:0000107 NCBI chr 6:75,618,317...75,638,591
Ensembl chr 6:75,618,416...75,638,591
JBrowse link
G ATP7B ATPase copper transporting beta ISO RGD PMID:24614235 RGD:11341682 NCBI chr11:15,892,549...15,942,070 JBrowse link
G BACE1 beta-secretase 1 ISO RGD PMID:18583042 RGD:13782134 NCBI chr 9:44,640,389...44,665,863
Ensembl chr 9:44,640,392...44,665,835
JBrowse link
G DBH dopamine beta-hydroxylase ISO RGD PMID:19276553 RGD:5129515 NCBI chr 1:273,204,407...273,225,562
Ensembl chr 1:273,204,400...273,225,558
JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,441...22,791,134
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,997,426
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:19643132 RGD:2325970
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:19643132 RGD:2325970 NCBI chr 3:32,749,329...33,149,350
Ensembl chr 3:32,752,351...33,143,499
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:19643132 RGD:2325970 NCBI chr 5:58,477,862...58,948,735
Ensembl chr 5:58,480,526...58,927,583
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,507...80,531,005
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,904
JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:16568477, PMID:17469137 RGD:12904039, RGD:12904041 NCBI chr 7:47,481,539...47,529,199
Ensembl chr 7:47,479,629...47,529,227
JBrowse link
G LRRK2 leucine rich repeat kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,240...71,944,938
JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:28232070 RGD:12910738 NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,026,722...72,056,439
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:19781568 RGD:5130971 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,511...6,730,881
JBrowse link
G TH tyrosine hydroxylase ISO RGD PMID:19781568 RGD:5130971 NCBI chr 2:1,499,628...1,506,180
Ensembl chr 2:1,499,618...1,506,615
JBrowse link
regulation of cellular response to manganese ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC30A10 solute carrier family 30 member 10 ISO (PMID:25319704) UniProtKB PMID:25319704 NCBI chr10:9,527,523...9,545,493 JBrowse link
response to manganese-induced endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,738,880...8,745,225
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,875...57,506,247
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,829
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    response to stimulus 8966
      response to chemical 5474
        response to inorganic substance 790
          response to metal ion 500
            response to manganese ion 36
              cellular response to manganese ion 22
                negative regulation of cellular response to manganese ion 0
                positive regulation of cellular response to manganese ion 0
                regulation of cellular response to manganese ion + 1
                response to manganese-induced endoplasmic reticulum stress 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.