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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to manganese ion
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Accession:GO:0071287 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
Synonyms:exact_synonym: cellular response to manganese


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cellular response to manganese ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A3galt2 alpha 1,3-galactosyltransferase 2 ISO RGD PMID:1569388 RGD:13831122 NCBI chrNW_004936474:16,135,076...16,138,930 JBrowse link
G App amyloid beta precursor protein ISO RGD PMID:18583042 RGD:13782134 NCBI chrNW_004936640:1,549,977...1,787,436 JBrowse link
G Atp13a2 ATPase cation transporting 13A2 ISO (PMID:22285144) ParkinsonsUK-UCL PMID:22285144 NCBI chrNW_004936474:3,968,216...3,980,821 JBrowse link
G Atp7b ATPase copper transporting beta ISO RGD PMID:24614235 RGD:11341682 NCBI chrNW_004936565:4,694,294...4,763,661 JBrowse link
G Bace1 beta-secretase 1 ISO RGD PMID:18583042 RGD:13782134 NCBI chrNW_004936542:2,514,297...2,539,088 JBrowse link
G Dbh dopamine beta-hydroxylase ISO RGD PMID:19276553 RGD:5129515 NCBI chrNW_004936669:3,302,014...3,326,233 JBrowse link
G Ddit3 DNA damage inducible transcript 3 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chrNW_004936646:1,665,019...1,669,212 JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chrNW_004936541:4,613,197...4,705,911 JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:19643132 RGD:2325970 NCBI chrNW_004936669:814,330...838,881 JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:19643132 RGD:2325970 NCBI chrNW_004936530:8,286,101...8,612,183 JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:19643132 RGD:2325970 NCBI chrNW_004936587:3,406,055...3,806,956 JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chrNW_004936492:10,513,908...10,528,281 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chrNW_004936487:13,348,465...13,352,717 JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:16568477, PMID:17469137 RGD:12904039, RGD:12904041 NCBI chrNW_004936471:36,547,552...36,601,327 JBrowse link
G Lrrk2 leucine rich repeat kinase 2 ISO (PMID:23628791) ParkinsonsUK-UCL PMID:23628791 NCBI chrNW_004936607:628,469...761,117 JBrowse link
G Mfn2 mitofusin 2 ISO RGD PMID:28232070 RGD:12910738 NCBI chrNW_004936474:767,754...795,258 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:19781568 RGD:5130971 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Th tyrosine hydroxylase ISO RGD PMID:19781568 RGD:5130971 NCBI chrNW_004936794:478,651...486,887 JBrowse link
regulation of cellular response to manganese ion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc30a10 solute carrier family 30 member 10 ISO (PMID:25319704) UniProtKB PMID:25319704 NCBI chrNW_004936650:2,252,554...2,267,990 JBrowse link
response to manganese-induced endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chrNW_004936492:2,114,478...2,115,969 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chrNW_004936712:413,602...454,443 JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chrNW_004936495:10,746,687...10,769,304 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    response to stimulus 6404
      response to chemical 3741
        response to inorganic substance 696
          response to metal ion 451
            response to manganese ion 35
              cellular response to manganese ion 22
                negative regulation of cellular response to manganese ion 0
                positive regulation of cellular response to manganese ion 0
                regulation of cellular response to manganese ion + 1
                response to manganese-induced endoplasmic reticulum stress 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.