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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to epidermal growth factor stimulus
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Accession:GO:0071364 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
Synonyms:exact_synonym: cellular response to EGF stimulus


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cellular response to epidermal growth factor stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 IEP RGD PMID:10209028 RGD:2306208 NCBI chr13:41,695,520...41,738,622
Ensembl chr13:41,695,183...41,738,658
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO (MGI:MGI:5292318|PMID:21712384) RGD PMID:21712384 MGI:MGI:5292318 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 9:81,518,163...81,548,871
Ensembl chr 9:81,518,176...81,548,871
JBrowse link
G Bag4 BAG cochaperone 4 ISO
IEA
(MGI:MGI:5292318|PMID:21712384)
GO_REF:0000107
RGD
Ensembl
PMID:21712384 GO_REF:0000107, MGI:MGI:5292318 NCBI chr16:71,057,709...71,075,874
Ensembl chr16:71,058,022...71,075,320
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 IEP RGD PMID:17855387 RGD:2306203 NCBI chr10:109,107,326...109,187,458
Ensembl chr10:109,107,389...109,187,115
JBrowse link
G Becn1 beclin 1 IEP RGD PMID:20539009 RGD:6483081 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEP RGD PMID:10659854 RGD:2303528 NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284
JBrowse link
G Cbl Cbl proto-oncogene IPI RGD PMID:22203672 RGD:11576305 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722
JBrowse link
G Cfl1 cofilin 1 IEP
IMP
RGD PMID:26324884, PMID:23704350 RGD:11568705, RGD:11570555 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IEP RGD PMID:16033771 RGD:11341689 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Col1a1 collagen type I alpha 1 chain IEP RGD PMID:2016852 RGD:2316227 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Dab2 DAB adaptor protein 2 IDA PMID:12473651 UniProt PMID:12473651 RGD:8553624 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Dab2ip DAB2 interacting protein IDA PMID:11812785 BHF-UCL PMID:11812785 RGD:632628 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286
JBrowse link
G Dusp22 dual specificity phosphatase 22 ISO (PMID:20018849) RGD PMID:20018849 NCBI chr17:34,986,589...35,037,297
Ensembl chr17:34,986,591...35,037,076
JBrowse link
G Dusp3 dual specificity phosphatase 3 ISO (PMID:28759036)
(MGI:MGI:6101044|PMID:28759036)
RGD PMID:28759036 MGI:MGI:6101044 NCBI chr10:89,904,578...89,918,296
Ensembl chr10:89,904,560...89,918,427
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 ISO
ISS
(PMID:9852145)
GO_REF:0000024
RGD
UniProt
PMID:9852145 GO_REF:0000024 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Egfr epidermal growth factor receptor IDA PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO
ISS
(PMID:27134172)
GO_REF:0000024
RGD
UniProt
PMID:27134172 GO_REF:0000024 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO
IEA
(MGI:MGI:82360|PMID:8702723)
GO_REF:0000107
RGD
Ensembl
PMID:8702723 GO_REF:0000107, MGI:MGI:82360 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IEP RGD PMID:15556944 RGD:9685545 NCBI chr 5:167,951,564...167,966,011
Ensembl chr 5:167,952,728...167,966,009
JBrowse link
G Foxc1 forkhead box C1 ISO (PMID:16492674) RGD PMID:16492674 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484
JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 ISO (PMID:19509291) RGD PMID:19509291 NCBI chr18:14,982,604...15,007,245 JBrowse link
G Git1 GIT ArfGAP 1 IDA RGD PMID:18523162 RGD:13513208 NCBI chr10:62,656,000...62,664,467
Ensembl chr10:62,656,000...62,664,466
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:24018045 RGD:13792711 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Gstp1 glutathione S-transferase pi 1 IEP RGD PMID:1908848 RGD:2317845 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 IEP RGD PMID:3062579 RGD:10041005 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein IEP RGD PMID:7623812 RGD:9686118 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit IEP RGD PMID:8070348 RGD:12911020 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K ISO (PMID:21712384) RGD PMID:21712384 NCBI chr10:63,775,639...63,796,879
Ensembl chr10:63,776,378...63,795,899
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO (MGI:MGI:5430891|PMID:17563371)
(PMID:17563371), (PMID:26242911)
RGD PMID:17563371, PMID:26242911 MGI:MGI:5430891 NCBI chr 1:142,525,041...142,615,673
Ensembl chr 1:142,525,046...142,615,673
JBrowse link
G Ireb2 iron responsive element binding protein 2 IDA RGD PMID:10889193 RGD:12910555 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein ISO
IEA
(PMID:26242911)
GO_REF:0000107
RGD
Ensembl
PMID:26242911 GO_REF:0000107 NCBI chr 3:110,618,256...110,638,024
Ensembl chr 3:110,618,298...110,638,046
JBrowse link
G Mars1 methionyl-tRNA synthetase 1 ISO (PMID:10791971) RGD PMID:10791971 NCBI chr 7:70,585,011...70,602,425
Ensembl chr 7:70,585,013...70,602,310
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 IEP RGD PMID:19821535 RGD:2316313 NCBI chr12:19,306,615...19,313,877
Ensembl chr12:19,306,607...19,314,016
JBrowse link
G Med1 mediator complex subunit 1 ISO
ISS
(PMID:16314496)
GO_REF:0000024
RGD
UniProt
PMID:16314496 GO_REF:0000024 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming IEP RGD PMID:11769575 RGD:2324971 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEP RGD PMID:7524476 RGD:10059620 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Ncl nucleolin ISO
IEA
(MGI:MGI:82360|PMID:8702723)
GO_REF:0000107
RGD
Ensembl
PMID:8702723 GO_REF:0000107, MGI:MGI:82360 NCBI chr 9:93,369,119...93,377,643
Ensembl chr 9:93,368,932...93,377,643
JBrowse link
G Pax2 paired box 2 IEP RGD PMID:11262416 RGD:2316756 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pde8a phosphodiesterase 8A ISO
IBA
(PMID:23509299)
PMID:21873635
(MGI:MGI:5484722|PMID:23509299)
RGD PMID:23509299, PMID:21873635 MGI:MGI:5484722, RGD:13792537 NCBI chr 1:143,036,083...143,160,395
Ensembl chr 1:143,036,218...143,159,433
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 ISO (PMID:22454520) RGD PMID:22454520 NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448
JBrowse link
G Plcg1 phospholipase C, gamma 1 IEA
ISO
ISS
GO_REF:0000107
(PMID:17229814), (PMID:22454520)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17229814, PMID:22454520 GO_REF:0000024, GO_REF:0000107 NCBI chr 3:156,727,642...156,758,307
Ensembl chr 3:156,727,642...156,758,307
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B IEP RGD PMID:10620493 RGD:10002737 NCBI chr10:82,800,704...82,816,735
Ensembl chr10:82,800,704...82,816,731
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO
ISS
(PMID:28074573)
GO_REF:0000024
RGD
UniProt
PMID:28074573 GO_REF:0000024 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999
JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 ISO
IBA
(PMID:27134172)
PMID:21873635
RGD PMID:27134172, PMID:21873635 RGD:13792537 NCBI chr 4:10,631,129...10,702,390
Ensembl chr 4:10,631,073...10,702,386
JBrowse link
G Rasa1 RAS p21 protein activator 1 IDA RGD PMID:2005883 RGD:10002731 NCBI chr 2:13,617,021...13,696,531
Ensembl chr 2:13,616,822...13,696,426
JBrowse link
G Snai2 snail family transcriptional repressor 2 ISO (PMID:18716062) RGD PMID:18716062 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Snx6 sorting nexin 6 IDA RGD PMID:18523162 RGD:13513208 NCBI chr 6:75,626,927...75,670,172
Ensembl chr 6:75,626,927...75,670,135
JBrowse link
G Sox9 SRY-box transcription factor 9 ISO
ISS
(MGI:MGI:5285125|PMID:21512138)
GO_REF:0000024
RGD
UniProt
PMID:21512138 GO_REF:0000024, MGI:MGI:5285125 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Stat5b signal transducer and activator of transcription 5B IDA PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Syap1 synapse associated protein 1 ISO (PMID:23300339)
(MGI:MGI:6114863|PMID:23300339)
RGD PMID:23300339 MGI:MGI:6114863 NCBI chr  X:33,528,071...33,562,584
Ensembl chr  X:33,528,081...33,562,589
JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 ISO (PMID:17720976) RGD PMID:17720976 NCBI chr 8:119,215,266...119,220,909
Ensembl chr 8:119,215,495...119,219,232
JBrowse link
G Vil1 villin 1 ISO (PMID:17229814) RGD PMID:17229814 NCBI chr 9:81,689,802...81,717,623
Ensembl chr 9:81,689,802...81,717,621
JBrowse link
G Zfp36 zinc finger protein 36 ISO
ISS
(PMID:20166898)
GO_REF:0000024
RGD
UniProt
PMID:20166898 GO_REF:0000024 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 ISO
ISS
(PMID:20166898)
GO_REF:0000024
RGD
UniProt
PMID:20166898 GO_REF:0000024 NCBI chr 6:103,308,032...103,313,074
Ensembl chr 6:103,308,045...103,313,074
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 ISO (PMID:20166898) RGD PMID:20166898 NCBI chr 6:7,417,416...7,423,447
Ensembl chr 6:7,417,425...7,421,456
JBrowse link
G Zpr1 ZPR1 zinc finger ISO (PMID:9852145) RGD PMID:9852145 NCBI chr 8:50,563,047...50,572,621
Ensembl chr 8:50,563,047...50,572,621
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    response to stimulus 10569
      response to endogenous stimulus 2026
        response to epidermal growth factor 67
          cellular response to epidermal growth factor stimulus 57
Path 2
Term Annotations click to browse term
  biological_process 20017
    response to stimulus 10569
      response to chemical 6330
        response to organic substance 3853
          cellular response to organic substance 2836
            cellular response to growth factor stimulus 765
              cellular response to epidermal growth factor stimulus 57
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.