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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to glucocorticoid stimulus
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Accession:GO:0071385 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.


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cellular response to glucocorticoid stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1 activin A receptor type 1 JBrowse link 3 44,432,476 44,539,680 RGD:2325236
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:2325276
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:2325673
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:1624291
RGD:13792537
RGD:8553594
G Asl argininosuccinate lyase JBrowse link 12 30,160,922 30,178,348 RGD:1599264
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:5130944
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:8662272
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:4889422
G Fam107a family with sequence similarity 107, member A JBrowse link 15 18,399,145 18,415,959 RGD:1600115
RGD:1624291
G Flt3 fms-related tyrosine kinase 3 JBrowse link 12 9,360,439 9,437,004 RGD:2302206
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:2317830
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 JBrowse link 2 95,320,147 95,322,701 RGD:5132633
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:2326089
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 13 96,222,093 96,238,845 RGD:1600115
RGD:1624291
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:4888522
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:8553931
G Mt-nd3 mitochondrially encoded NADH dehydrogenase 3 JBrowse link MT 9,451 9,798 RGD:5507827
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming JBrowse link 1 214,725,482 214,756,653 RGD:2324966
G Myod1 myogenic differentiation 1 JBrowse link 1 102,396,538 102,399,248 RGD:1624291
RGD:1600115
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:1624291
RGD:1600115
G Orm1 orosomucoid 1 JBrowse link 5 79,179,668 79,182,820 RGD:2316645
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:1600115
RGD:1624291
G RT1-Ba RT1 class II, locus Ba JBrowse link 20 4,066,133 4,070,726 RGD:5147665
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:5147665
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N JBrowse link 6 128,073,344 128,080,878 RGD:5147415
G Sstr2 somatostatin receptor 2 JBrowse link 10 102,136,283 102,143,449 RGD:2325001
RGD:13792537
G Sstr3 somatostatin receptor 3 JBrowse link 7 119,760,881 119,768,082 RGD:2325001
G Sstr4 somatostatin receptor 4 JBrowse link 3 142,739,781 142,741,644 RGD:2325001
RGD:13792537
G Sstr5 somatostatin receptor 5 JBrowse link 10 14,847,749 14,853,827 RGD:2325001
RGD:13792537
G Stc1 stanniocalcin 1 JBrowse link 15 50,891,137 50,901,791 RGD:2324697
G Ube2l3 ubiquitin-conjugating enzyme E2L 3 JBrowse link 11 88,047,186 88,088,477 RGD:1624291
G Ucn2 urocortin 2 JBrowse link 8 117,727,216 117,728,765 RGD:2317018
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:2317062
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 JBrowse link 9 95,256,628 95,302,822 RGD:2317062
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 JBrowse link 9 95,241,609 95,302,822 RGD:2317072
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 JBrowse link 14 22,375,428 22,486,291 RGD:2317062
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 JBrowse link 14 22,724,399 22,736,148 RGD:2317062
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1624291
RGD:1600115
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 6 103,308,032 103,313,074 RGD:1624291
RGD:1600115
G Zfp36l2 zinc finger protein 36, C3H type-like 2 JBrowse link 6 7,417,416 7,423,447 RGD:1624291
cellular response to corticosterone stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 JBrowse link 7 41,114,606 41,223,138 RGD:2317731
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:10402192
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:13432032
G Lmnb1 lamin B1 JBrowse link 18 51,785,111 51,822,264 RGD:2312627
G Npas4 neuronal PAS domain protein 4 JBrowse link 1 220,260,310 220,278,177 RGD:1624291
RGD:1600115
cellular response to cortisol stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:7829730
G Klf9 Kruppel-like factor 9 JBrowse link 1 240,908,483 240,933,198 RGD:1600115
RGD:1624291
cellular response to dexamethasone stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:2315579
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:11081015
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:2315579
G Agtr1a angiotensin II receptor, type 1a JBrowse link 17 35,907,102 35,958,136 RGD:1643596
G Agtr1b angiotensin II receptor, type 1b JBrowse link 2 105,149,020 105,224,335 RGD:1643596
G Agtr2 angiotensin II receptor, type 2 JBrowse link X 119,389,480 119,393,845 RGD:1643596
G Andpro androgen regulated protein JBrowse link 3 143,893,005 143,899,609 RGD:14696819
G Aqp1 aquaporin 1 JBrowse link 4 85,551,503 85,563,683 RGD:1624291
RGD:1600115
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:4144048
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:4144048
G Asl argininosuccinate lyase JBrowse link 12 30,160,922 30,178,348 RGD:1599316
G Ass1 argininosuccinate synthase 1 JBrowse link 3 10,327,411 10,375,847 RGD:4139912
G Atp5f1a ATP synthase F1 subunit alpha JBrowse link 18 74,156,553 74,164,490 RGD:13703103
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:11353844
G Bmi1 BMI1 proto-oncogene, polycomb ring finger JBrowse link 17 85,360,439 85,370,283 RGD:5507827
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1643596
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:2316203
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:1624291
RGD:1600115
G Cbx3 chromobox 3 JBrowse link 4 81,243,809 81,257,898 RGD:5507827
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8548859
G Cflar CASP8 and FADD-like apoptosis regulator JBrowse link 9 65,534,608 65,586,395 RGD:11341697
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:5490546
G Ddit4 DNA-damage-inducible transcript 4 JBrowse link 20 29,509,283 29,511,382 RGD:1624291
RGD:1600115
G Dnmt3b DNA methyltransferase 3 beta JBrowse link 3 149,131,541 149,170,061 RGD:9590112
G Dspp dentin sialophosphoprotein JBrowse link 14 6,926,972 6,933,079 RGD:5132633
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:5131522
G Eif4e eukaryotic translation initiation factor 4E JBrowse link 2 243,819,616 243,853,987 RGD:1624291
RGD:1600115
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 16 68,954,860 68,968,248 RGD:1624291
RGD:1600115
G Eln elastin JBrowse link 12 24,978,478 25,021,864 RGD:9585723
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:7327218
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:9685543
G Fbxo32 F-box protein 32 JBrowse link 7 98,065,664 98,098,071 RGD:1624291
RGD:1600115
G Fech ferrochelatase JBrowse link 18 59,941,992 59,975,192 RGD:4144799
G Foxo1 forkhead box O1 JBrowse link 2 141,451,234 141,527,016 RGD:10044266
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:1643596
G Gjb2 gap junction protein, beta 2 JBrowse link 15 37,377,313 37,394,494 RGD:11568664
G Hmbs hydroxymethylbilane synthase JBrowse link 8 48,667,278 48,674,673 RGD:4144799
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 13 96,222,093 96,238,845 RGD:10059314
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 RGD:4145599
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:11520786
G Ifnb1 interferon beta 1 JBrowse link 5 106,865,192 106,865,746 RGD:1624291
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:12904722
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:12904722
G Igfals insulin-like growth factor binding protein, acid labile subunit JBrowse link 10 14,240,308 14,243,554 RGD:12911020
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:7829782
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1624291
G L1cam L1 cell adhesion molecule JBrowse link X 156,901,244 156,928,064 RGD:11570520
G Mettl21c methyltransferase like 21C JBrowse link 9 50,750,971 50,762,082 RGD:1624291
RGD:1600115
G Mfn1 mitofusin 1 JBrowse link 2 118,929,738 118,971,689 RGD:13204845
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:13204845
G Mir155 microRNA 155 JBrowse link 11 24,176,603 24,176,667 RGD:1624291
G Mir21 microRNA 21 JBrowse link 10 73,902,210 73,902,301 RGD:1624291
G Mstn myostatin JBrowse link 9 53,310,977 53,315,804 RGD:1624291
RGD:1600115
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:12789704
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:729108
RGD:1624291
G Nts neurotensin JBrowse link 7 44,111,594 44,120,998 RGD:9727457
G Pck1 phosphoenolpyruvate carboxykinase 1 JBrowse link 3 171,213,936 171,219,885 RGD:13792537
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:2311680
G Pnmt phenylethanolamine-N-methyltransferase JBrowse link 10 86,340,893 86,342,501 RGD:5130762
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:2317888
G Rpl32 ribosomal protein L32 JBrowse link 4 147,715,480 147,719,044 RGD:11038821
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:1624291
RGD:1600115
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:4144112
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:8547845
G Serpinf1 serpin family F member 1 JBrowse link 10 62,241,750 62,254,145 RGD:2312357
G Smyd3 SET and MYND domain containing 3 JBrowse link 13 97,330,120 97,807,813 RGD:1624291
G Srd5a1 steroid 5 alpha-reductase 1 JBrowse link 1 36,320,504 36,354,694 RGD:4891941
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:4145599
G Tfap4 transcription factor AP-4 JBrowse link 10 11,204,616 11,222,975 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1643596
G Trim63 tripartite motif containing 63 JBrowse link 5 152,533,362 152,547,138 RGD:1624291
G Usp8 ubiquitin specific peptidase 8 JBrowse link 3 119,173,818 119,222,499 RGD:13208949
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:7483563
glucocorticoid mediated signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07031756.2 RGD:1600115
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:1600115
G Sgk1 serum/glucocorticoid regulated kinase 1 JBrowse link 1 24,185,451 24,302,309 RGD:1642763
negative regulation of glucocorticoid mediated signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crebrf CREB3 regulatory factor JBrowse link 10 16,693,846 16,753,162 RGD:1624291
RGD:1600115
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:1624291
regulation of glucocorticoid mediated signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap13 A-kinase anchoring protein 13 JBrowse link 1 137,089,558 137,315,272 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19312
    response to stimulus 10391
      response to endogenous stimulus 2097
        response to hormone 1334
          response to steroid hormone 542
            response to corticosteroid 324
              cellular response to corticosteroid stimulus 127
                cellular response to glucocorticoid stimulus 120
                  cellular response to corticosterone stimulus 5
                  cellular response to cortisol stimulus 2
                  cellular response to cortisone stimulus 0
                  cellular response to dexamethasone stimulus 73
                  glucocorticoid mediated signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 19312
    response to stimulus 10391
      response to chemical 6304
        response to organic substance 3780
          response to hormone 1334
            response to steroid hormone 542
              response to corticosteroid 324
                response to glucocorticoid 300
                  cellular response to glucocorticoid stimulus 120
                    cellular response to corticosterone stimulus 5
                    cellular response to cortisol stimulus 2
                    cellular response to cortisone stimulus 0
                    cellular response to dexamethasone stimulus 73
                    glucocorticoid mediated signaling pathway + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.