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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to osmotic stress
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Accession:GO:0071470 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
Synonyms:exact_synonym: cellular osmotic response;   cellular osmotic stress response


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cellular response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx3x DEAD-box helicase 3, X-linked JBrowse link X 10,400,363 10,414,010 RGD:1624291
G Dysf dysferlin JBrowse link 4 115,700,942 115,901,873 RGD:1624291
G Lrrc8c leucine rich repeat containing 8 VRAC subunit C JBrowse link 14 5,283,655 5,378,738 RGD:13673739
G Lrrc8d leucine rich repeat containing 8 VRAC subunit D JBrowse link 14 5,085,606 5,194,808 RGD:1600115
RGD:1624291
RGD:13673739
G Lrrc8e leucine rich repeat containing 8 VRAC subunit E JBrowse link 12 2,557,267 2,568,416 RGD:1600115
RGD:1624291
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
G Relb RELB proto-oncogene, NF-kB subunit JBrowse link 1 80,517,081 80,545,019 RGD:7777165
G Serpinb6a serpin family B member 6A JBrowse link 17 32,154,747 32,209,598 RGD:1624291
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:1624291
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
RGD:1600115
G Zfand1 zinc finger AN1-type containing 1 JBrowse link 2 93,656,895 93,666,745 RGD:1624291
cellular hyperosmotic response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp1 aquaporin 1 JBrowse link 4 85,551,503 85,563,683 RGD:1624291
RGD:1600115
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1624291
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:1624291
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:9685546
G Mapk10 mitogen activated protein kinase 10 JBrowse link 14 8,079,955 8,371,508 RGD:10412695
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:10412695
G Rcsd1 RCSD domain containing 1 JBrowse link 13 83,854,650 83,917,040 RGD:1624291
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:12879856
G Slc6a12 solute carrier family 6 member 12 JBrowse link 4 153,921,199 153,941,333 RGD:2316970
G Ybx3 Y box binding protein 3 JBrowse link 4 165,606,819 165,630,041 RGD:1624291
RGD:1600115
cellular hyperosmotic salinity response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:2301086
G Akr1b1 aldo-keto reductase family 1 member B JBrowse link 4 61,706,866 61,720,959 RGD:1624291
G Fxyd2 FXYD domain-containing ion transport regulator 2 JBrowse link 8 49,710,334 49,717,492 RGD:1598989
G Mir100 microRNA 100 JBrowse link 8 45,746,948 45,747,027 RGD:1624291
G Mir137 microRNA 137 JBrowse link 2 221,658,106 221,658,207 RGD:1624291
G Mir204 microRNA 204 JBrowse link 1 240,403,000 240,403,109 RGD:1624291
G Mir29b1 microRNA 29b-1 JBrowse link 4 58,344,310 58,344,390 RGD:1624291
G Mir29b2 microRNA 29b-2 JBrowse link 13 113,782,057 113,782,137 RGD:1624291
G Mir30b microRNA 30b JBrowse link 7 109,282,662 109,282,747 RGD:1624291
G Mir451a microRNA 451a JBrowse link 10 65,291,204 65,291,275 RGD:1624291
G Mir7b microRNA 7b JBrowse link 9 10,812,432 10,812,541 RGD:1624291
G Mir9-3 microRNA 9-3 JBrowse link 1 141,229,353 141,229,442 RGD:1624291
G Mir99a microRNA 99a JBrowse link 11 16,052,153 16,052,233 RGD:1624291
G Slc12a1 solute carrier family 12 member 1 JBrowse link 3 117,421,531 117,498,372 RGD:1624291
G Xrcc5 X-ray repair cross complementing 5 JBrowse link 9 79,659,275 79,748,050 RGD:2317102
G Xrcc6 X-ray repair cross complementing 6 JBrowse link 7 123,259,881 123,280,613 RGD:2317102
cellular hypotonic response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp5 aquaporin 5 JBrowse link 7 141,249,044 141,252,576 RGD:1600115
RGD:1624291
G Mylk myosin light chain kinase JBrowse link 11 69,013,060 69,260,039 RGD:1624291
G Oxsr1 oxidative stress responsive kinase 1 JBrowse link 8 127,920,349 128,009,951 RGD:1624291
G Prkg2 protein kinase cGMP-dependent 2 JBrowse link 14 12,217,121 12,313,616 RGD:1624291
G Slc12a6 solute carrier family 12, member 6 JBrowse link 3 103,752,213 103,852,686 RGD:1624291
G Stk39 serine threonine kinase 39 JBrowse link 3 54,359,449 54,625,702 RGD:1624291
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:2317141
cellular hypotonic salinity response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc12a6 solute carrier family 12, member 6 JBrowse link 3 103,752,213 103,852,686 RGD:1624291
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
cellular response to non-ionic osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1624291
cellular response to salt stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp1 aquaporin 1 JBrowse link 4 85,551,503 85,563,683 RGD:1624291
RGD:1600115
G Capn3 calpain 3 JBrowse link 3 112,227,486 112,278,408 RGD:1600115
RGD:1624291
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 6 103,308,032 103,313,074 RGD:1624291
RGD:1600115
intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
G Scn2a sodium voltage-gated channel alpha subunit 2 JBrowse link 3 51,687,910 51,822,008 RGD:1624291
RGD:1600115
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1624291
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:1624291
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:1624291
G Ptger2 prostaglandin E receptor 2 JBrowse link 15 19,336,029 19,349,759 RGD:1624291
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1624291
G Ybx3 Y box binding protein 3 JBrowse link 4 165,606,819 165,630,041 RGD:1624291
RGD:1600115
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:1624291
RGD:1600115
osmosensory signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Oxsr1 oxidative stress responsive kinase 1 JBrowse link 8 127,920,349 128,009,951 RGD:1624291
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
RGD:13792537
G Wnk3 WNK lysine deficient protein kinase 3 JBrowse link X 20,316,081 20,459,245 RGD:1624291
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291
regulation of cellular hyperosmotic salinity response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Efhd1 EF-hand domain family, member D1 JBrowse link 9 94,362,249 94,408,884 RGD:1624291
G Letm1 leucine zipper and EF-hand containing transmembrane protein 1 JBrowse link 14 82,227,790 82,267,298 RGD:1600115
RGD:1624291
G Micu1 mitochondrial calcium uptake 1 JBrowse link 20 29,284,833 29,433,617 RGD:1600115
RGD:1624291
G Slc25a23 solute carrier family 25 member 23 JBrowse link 9 9,987,988 10,003,599 RGD:1624291
regulation of cellular response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin JBrowse link 1 197,986,384 197,999,726 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    response to stimulus 10526
      response to stress 4032
        response to osmotic stress 123
          cellular response to osmotic stress 58
            cellular hyperosmotic response + 30
            cellular hypotonic response + 8
            cellular response to non-ionic osmotic stress 1
            cellular response to salt stress + 25
            intrinsic apoptotic signaling pathway in response to osmotic stress + 9
            osmosensory signaling pathway + 3
            regulation of cellular response to osmotic stress + 12
Path 2
Term Annotations click to browse term
  biological_process 19858
    response to stimulus 10526
      response to chemical 6306
        cellular response to chemical stimulus 3497
          cellular response to chemical stress 417
            cellular response to osmotic stress 58
              cellular hyperosmotic response + 30
              cellular hypotonic response + 8
              cellular response to non-ionic osmotic stress 1
              cellular response to salt stress + 25
              intrinsic apoptotic signaling pathway in response to osmotic stress + 9
              osmosensory signaling pathway + 3
              regulation of cellular response to osmotic stress + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.