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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular hyperosmotic salinity response
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Accession:GO:0071475 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
Synonyms:exact_synonym: cellular response to hyperosmotic salt stress


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cellular hyperosmotic salinity response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO RGD PMID:17762165 RGD:2301086 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B ISO (PMID:8435445) UniProtKB PMID:8435445 NCBI chr 7:126,400,861...126,417,756
Ensembl chr 7:138,912,953...138,924,095
JBrowse link
G SLC12A1 solute carrier family 12 member 1 ISO (MGI:MGI:4947009|PMID:21228109) MGI PMID:21228109 MGI:MGI:4947009 NCBI chr15:27,155,331...27,252,995
Ensembl chr15:45,479,583...45,577,084
JBrowse link
G XRCC5 X-ray repair cross complementing 5 ISO RGD PMID:11175667 RGD:2317102 NCBI chr2B:103,371,459...103,468,419
Ensembl chr2B:221,972,742...222,071,235
JBrowse link
G XRCC6 X-ray repair cross complementing 6 ISO RGD PMID:11175667 RGD:2317102 NCBI chr22:22,516,281...22,557,379
Ensembl chr22:40,603,038...40,643,314
JBrowse link
regulation of cellular hyperosmotic salinity response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EFHD1 EF-hand domain family member D1 ISO (PMID:26975899) UniProt PMID:26975899 NCBI chr2B:119,865,065...119,914,446 JBrowse link
G LETM1 leucine zipper and EF-hand containing transmembrane protein 1 ISO (PMID:26975899) UniProt PMID:26975899 NCBI chr 4:1,953,033...1,994,958
Ensembl chr 4:1,862,788...1,900,901
JBrowse link
G MICU1 mitochondrial calcium uptake 1 ISO (PMID:26975899) UniProt PMID:26975899 NCBI chr10:68,887,361...69,152,242
Ensembl chr10:71,353,886...71,558,246
JBrowse link
G SLC25A23 solute carrier family 25 member 23 ISO (PMID:26975899) UniProt PMID:26975899 NCBI chr19:5,474,538...5,487,364
Ensembl chr19:6,388,937...6,410,480
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12524
    response to stimulus 6721
      response to stress 3229
        response to osmotic stress 109
          hyperosmotic response 37
            hyperosmotic salinity response 19
              cellular hyperosmotic salinity response 9
                negative regulation of cellular hyperosmotic salinity response + 0
                regulation of cellular hyperosmotic salinity response + 4
Path 2
Term Annotations click to browse term
  biological_process 12524
    cellular process 11624
      cellular response to stimulus 5312
        cellular response to environmental stimulus 364
          cellular response to abiotic stimulus 364
            cellular response to osmotic stress 47
              cellular hyperosmotic response 19
                cellular hyperosmotic salinity response 9
                  negative regulation of cellular hyperosmotic salinity response + 0
                  regulation of cellular hyperosmotic salinity response + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.