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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular hyperosmotic salinity response
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Accession:GO:0071475 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
Synonyms:exact_synonym: cellular response to hyperosmotic salt stress


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cellular hyperosmotic salinity response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO RGD PMID:17762165 RGD:2301086 NCBI chrNW_004936763:1,225,355...1,308,257 JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B ISO (PMID:8435445) UniProtKB PMID:8435445 NCBI chrNW_004936579:1,312,175...1,328,397 JBrowse link
G Fxyd2 FXYD domain containing ion transport regulator 2 ISO RGD PMID:15280368 RGD:1598989 NCBI chrNW_004936542:2,956,784...2,961,076 JBrowse link
G Slc12a1 solute carrier family 12 member 1 ISO (MGI:MGI:4947009|PMID:21228109) MGI PMID:21228109 MGI:MGI:4947009 NCBI chrNW_004936471:10,564,530...10,648,124 JBrowse link
G Xrcc5 X-ray repair cross complementing 5 ISO RGD PMID:11175667 RGD:2317102 NCBI chrNW_004936586:1,055,478...1,137,924 JBrowse link
G Xrcc6 X-ray repair cross complementing 6 ISO RGD PMID:11175667 RGD:2317102 NCBI chrNW_004936492:303,843...325,812 JBrowse link
regulation of cellular hyperosmotic salinity response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efhd1 EF-hand domain family member D1 ISO (PMID:26975899) UniProt PMID:26975899 NCBI chrNW_004936525:4,445,779...4,484,674 JBrowse link
G Letm1 leucine zipper and EF-hand containing transmembrane protein 1 ISO (PMID:26975899) UniProt PMID:26975899 NCBI chrNW_004936477:21,550,104...21,589,662 JBrowse link
G Micu1 mitochondrial calcium uptake 1 ISO (PMID:26975899) UniProt PMID:26975899 NCBI chrNW_004936521:6,400,849...6,576,304 JBrowse link
G Slc25a23 solute carrier family 25 member 23 ISO (PMID:26975899) UniProt PMID:26975899 NCBI chrNW_004936588:3,792,760...3,804,788 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    response to stimulus 6404
      response to stress 3056
        response to osmotic stress 100
          hyperosmotic response 34
            hyperosmotic salinity response 17
              cellular hyperosmotic salinity response 10
                negative regulation of cellular hyperosmotic salinity response + 0
                regulation of cellular hyperosmotic salinity response + 4
Path 2
Term Annotations click to browse term
  biological_process 11962
    cellular process 11135
      cellular response to stimulus 5123
        cellular response to environmental stimulus 355
          cellular response to abiotic stimulus 355
            cellular response to osmotic stress 46
              cellular hyperosmotic response 19
                cellular hyperosmotic salinity response 10
                  negative regulation of cellular hyperosmotic salinity response + 0
                  regulation of cellular hyperosmotic salinity response + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.