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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to fluid shear stress
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Accession:GO:0071498 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.


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cellular response to fluid shear stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car2 carbonic anhydrase 2 IEP RGD PMID:16777439 RGD:1600700 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Has2 hyaluronan synthase 2 ISO (PMID:21551265) RGD PMID:21551265 NCBI chr 7:96,438,046...96,464,049
Ensembl chr 7:96,438,046...96,464,049
JBrowse link
G Hdac3 histone deacetylase 3 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:25190803)
Ensembl
UniProt
RGD
PMID:25190803 GO_REF:0000024, GO_REF:0000107 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303
JBrowse link
G Hdac5 histone deacetylase 5 ISO (MGI:MGI:4440396|PMID:20181743) RGD PMID:20181743 MGI:MGI:4440396 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Klf2 Kruppel-like factor 2 ISO (PMID:22327366) RGD PMID:22327366 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Mef2c myocyte enhancer factor 2C IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:4440396|PMID:20181743)
Ensembl
UniProt
RGD
PMID:20181743 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4440396 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Mmp1 matrix metallopeptidase 1 IEP RGD PMID:19880665 RGD:7207384 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp13 matrix metallopeptidase 13 IEP RGD PMID:21246051 RGD:10043175 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP RGD PMID:21637818 RGD:7207287 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 ISO
ISS
(MGI:MGI:4440396|PMID:20181743)
GO_REF:0000024
RGD
UniProt
PMID:20181743 GO_REF:0000024, MGI:MGI:4440396 NCBI chr 7:98,820,799...98,960,878
Ensembl chr 7:98,820,812...98,960,837
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO
ISS
(PMID:25190803)
GO_REF:0000024
RGD
UniProt
PMID:25190803 GO_REF:0000024 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO (PMID:19265036)
(MGI:MGI:5315687|PMID:19265036)
RGD PMID:19265036 MGI:MGI:5315687 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
G Plau plasminogen activator, urokinase IEP RGD PMID:19166201 RGD:7241210 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO (MGI:MGI:5608648|PMID:24841674) RGD PMID:24841674 MGI:MGI:5608648 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta ISO (MGI:MGI:5608648|PMID:24841674) RGD PMID:24841674 MGI:MGI:5608648 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO (MGI:MGI:5608648|PMID:24841674) RGD PMID:24841674 MGI:MGI:5608648 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO (MGI:MGI:5608648|PMID:24841674) RGD PMID:24841674 MGI:MGI:5608648 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 IEP RGD PMID:20537494 RGD:11060271 NCBI chr 4:28,947,951...28,953,261
Ensembl chr 4:28,947,965...28,953,067
JBrowse link
G Xbp1 X-box binding protein 1 ISS
ISO
GO_REF:0000024
(PMID:25190803), (PMID:25280941)
UniProt
RGD
PMID:25190803, PMID:25280941 GO_REF:0000024 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
cellular response to laminar fluid shear stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ass1 argininosuccinate synthase 1 ISO (PMID:21106532) RGD PMID:21106532 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Klf2 Kruppel-like factor 2 ISO (PMID:23043106) RGD PMID:23043106 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Klf4 Kruppel like factor 4 ISO (PMID:22430140) RGD PMID:22430140 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO (PMID:23043106) RGD PMID:23043106 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO (PMID:23043106) RGD PMID:23043106 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Xbp1 X-box binding protein 1 ISO
ISS
(PMID:25280941)
GO_REF:0000024
RGD
UniProt
PMID:25280941 GO_REF:0000024 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
vascular endothelial cell response to fluid shear stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Socs5 suppressor of cytokine signaling 5 ISO (MGI:MGI:5659826|PMID:24255059) RGD PMID:24255059 MGI:MGI:5659826 NCBI chr 6:10,671,311...10,705,610
Ensembl chr 6:10,674,371...10,704,977
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    response to stimulus 10570
      response to stress 4060
        cellular response to stress 1993
          cellular response to fluid shear stress 23
            cellular response to laminar fluid shear stress + 6
            cellular response to oscillatory fluid shear stress + 0
            cellular response to pulsatile fluid shear stress + 0
            vascular endothelial cell response to fluid shear stress + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.