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ONTOLOGY REPORT - ANNOTATIONS


Term:semaphorin-plexin signaling pathway
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Accession:GO:0071526 term browser browse the term
Definition:A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.
Synonyms:exact_synonym: semaphorin-plexin signalling pathway


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semaphorin-plexin signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgdia Rho GDP dissociation inhibitor alpha JBrowse link 10 109,754,012 109,757,506 RGD:1624291
RGD:1600115
G Crmp1 collapsin response mediator protein 1 JBrowse link 14 78,266,931 78,312,777 RGD:1624291
G Farp2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 JBrowse link 9 100,660,366 100,767,940 RGD:1624291
G Flna filamin A JBrowse link X 156,460,785 156,487,245 RGD:1624291
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:1600115
RGD:1624291
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Pkhd1l1 PKHD1 like 1 JBrowse link 7 83,373,022 83,548,944 RGD:1600115
G Plxna2 plexin A2 JBrowse link 13 113,373,569 113,570,774 RGD:1624291
G Plxna4 plexin A4 JBrowse link 4 59,439,489 59,883,637 RGD:1624291
G Plxnb1 plexin B1 JBrowse link 8 117,832,826 117,858,515 RGD:1624291
G Plxnb2 plexin B2 JBrowse link 7 130,135,484 130,161,568 RGD:1624291
G Plxnb3 plexin B3 JBrowse link X 157,015,297 157,030,147 RGD:8554409
RGD:1624291
G Plxnd1 plexin D1 JBrowse link 4 147,854,309 147,894,170 RGD:1624291
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:8554409
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:1624291
RGD:13792537
G Sema3b semaphorin 3B JBrowse link 8 116,353,791 116,362,655 RGD:13792537
G Sema3c semaphorin 3C JBrowse link 4 14,318,276 14,490,438 RGD:1624291
RGD:13792537
G Sema3d semaphorin 3D JBrowse link 4 19,224,378 19,413,519 RGD:13792537
G Sema3e semaphorin 3E JBrowse link 4 17,314,745 17,594,659 RGD:1624291
RGD:13792537
G Sema3f semaphorin 3F JBrowse link 8 116,439,996 116,469,915 RGD:13792537
G Sema3g semaphorin 3G JBrowse link 16 7,303,582 7,315,214 RGD:13792537
G Sema4a semaphorin 4A JBrowse link 2 187,799,568 187,823,014 RGD:1624291
RGD:13792537
G Sema4b semaphorin 4B JBrowse link 1 141,986,145 142,014,400 RGD:13792537
G Sema4c semaphorin 4C JBrowse link 9 43,129,413 43,140,442 RGD:1624291
RGD:13792537
G Sema4d semaphorin 4D JBrowse link 17 13,516,276 13,538,513 RGD:1624291
RGD:13792537
G Sema4f ssemaphorin 4F JBrowse link 4 113,738,225 113,764,532 RGD:13792537
G Sema4g semaphorin 4G JBrowse link 1 264,738,935 264,753,399 RGD:13792537
G Sema5a semaphorin 5A JBrowse link 2 85,377,318 85,808,970 RGD:1624291
RGD:13792537
RGD:1600115
G Sema5b semaphorin 5B JBrowse link 11 68,304,844 68,435,109 RGD:13792537
G Sema6a semaphorin 6A JBrowse link 18 41,330,519 41,451,813 RGD:1624291
RGD:13792537
G Sema6b semaphorin 6B JBrowse link 9 10,934,273 10,951,252 RGD:13792537
G Sema6c semaphorin 6C JBrowse link 2 196,330,777 196,347,218 RGD:13792537
G Sema6d semaphorin 6D JBrowse link 3 116,899,906 116,958,059 RGD:13792537
G Sema7a semaphorin 7A (John Milton Hagen blood group) JBrowse link 8 62,723,788 62,746,530 RGD:13792537
G Sh3bp1 SH3-domain binding protein 1 JBrowse link 7 120,125,747 120,138,148 RGD:1624291
RGD:1600115
positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:1624291
RGD:1600115
regulation of semaphorin-plexin signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:1624291
RGD:1600115
G Mir23a microRNA 23a JBrowse link 19 25,318,582 25,318,656 RGD:1624291
G Mir23b microRNA 23b JBrowse link 17 823,222 823,318 RGD:1624291
G Mir27a microRNA 27a JBrowse link 19 25,318,736 25,318,822 RGD:1624291
G Mir27b microRNA 27b JBrowse link 17 823,461 823,557 RGD:1624291
G Ncam1 neural cell adhesion molecule 1 JBrowse link 8 53,836,797 54,134,881 RGD:1624291
semaphorin-plexin signaling pathway involved in axon guidance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Plxna1 plexin A1 JBrowse link 4 121,217,658 121,262,697 RGD:13792537
G Plxna2 plexin A2 JBrowse link 13 113,373,569 113,570,774 RGD:13792537
G Plxna3 plexin A3 JBrowse link X 156,363,400 156,379,433 RGD:1624291
RGD:13792537
G Plxna4 plexin A4 JBrowse link 4 59,439,489 59,883,637 RGD:1624291
RGD:13792537
G Plxnb1 plexin B1 JBrowse link 8 117,832,826 117,858,515 RGD:13792537
G Plxnb2 plexin B2 JBrowse link 7 130,135,484 130,161,568 RGD:13792537
G Plxnb3 plexin B3 JBrowse link X 157,015,297 157,030,147 RGD:13792537
G Plxnc1 plexin C1 JBrowse link 7 35,848,083 36,000,969 RGD:13792537
G Plxnd1 plexin D1 JBrowse link 4 147,854,309 147,894,170 RGD:13792537
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:1624291
G Sema3f semaphorin 3F JBrowse link 8 116,439,996 116,469,915 RGD:1624291
semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Plxnb1 plexin B1 JBrowse link 8 117,832,826 117,858,515 RGD:1624291
G Sema4d semaphorin 4D JBrowse link 17 13,516,276 13,538,513 RGD:1624291
semaphorin-plexin signaling pathway involved in neuron projection guidance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Nrp2 neuropilin 2 JBrowse link 9 69,496,875 69,609,802 RGD:1624291
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:1624291
G Sema3f semaphorin 3F JBrowse link 8 116,439,996 116,469,915 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    signaling 7553
      signal transduction 6968
        cell surface receptor signaling pathway 2772
          semaphorin-plexin signaling pathway 46
            negative regulation of semaphorin-plexin signaling pathway 0
            positive regulation of semaphorin-plexin signaling pathway + 1
            regulation of semaphorin-plexin signaling pathway + 7
            semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis 2
            semaphorin-plexin signaling pathway involved in neuron projection guidance + 13
            semaphorin-plexin signaling pathway involved in outflow tract morphogenesis + 1
            semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          signal transduction 6968
            cell surface receptor signaling pathway 2772
              semaphorin-plexin signaling pathway 46
                negative regulation of semaphorin-plexin signaling pathway 0
                positive regulation of semaphorin-plexin signaling pathway + 1
                regulation of semaphorin-plexin signaling pathway + 7
                semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis 2
                semaphorin-plexin signaling pathway involved in neuron projection guidance + 13
                semaphorin-plexin signaling pathway involved in outflow tract morphogenesis + 1
                semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.