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ONTOLOGY REPORT - ANNOTATIONS


Term:response to transforming growth factor beta
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Accession:GO:0071559 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
Synonyms:exact_synonym: response to TGF-beta stimulus;   response to TGFbeta stimulus;   response to transforming growth factor beta stimulus


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response to transforming growth factor beta term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cald1 caldesmon 1 NOT ISO (MGI:MGI:5582864|PMID:24036928) UniProtKB PMID:24036928 MGI:MGI:5582864 NCBI chrNW_004955494:7,578,162...7,675,558 JBrowse link
G Cited1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 ISO (PMID:9707553) UniProtKB PMID:9707553 NCBI chrNW_004955475:11,722,514...11,725,067 JBrowse link
G Dspp dentin sialophosphoprotein ISO RGD PMID:22012415 RGD:12914763 NCBI chrNW_004955474:2,254,842...2,259,303 JBrowse link
G Edn1 endothelin 1 ISO RGD PMID:11061980 RGD:8662323 NCBI chrNW_004955465:2,287,906...2,314,945 JBrowse link
G Eng endoglin ISO RGD PMID:22941949 RGD:7248789 NCBI chrNW_004955419:818,797...853,319 JBrowse link
G Fndc4 fibronectin type III domain containing 4 ISO (PMID:27066907) UniProtKB PMID:27066907 NCBI chrNW_004955469:9,456,964...9,459,721 JBrowse link
G Gdf10 growth differentiation factor 10 ISO RGD PMID:10079200 RGD:2316373 NCBI chrNW_004955556:2,185,121...2,195,150 JBrowse link
G Il1r1 interleukin 1 receptor type 1 ISO RGD PMID:9233842 RGD:8662880 NCBI chrNW_004955470:7,685,498...7,703,374 JBrowse link
G Itgb1 integrin subunit beta 1 ISO TGF-beta2 RGD PMID:18378961 RGD:2325302 NCBI chrNW_004955462:4,454,809...4,483,227 JBrowse link
G Men1 menin 1 ISO RGD PMID:15054094 RGD:1304318 NCBI chrNW_004955422:20,356,491...20,363,374 JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming ISO RGD PMID:15980276 RGD:8693640 NCBI chrNW_004955476:11,108,826...11,135,697 JBrowse link
G Mxra5 matrix remodeling associated 5 ISO (PMID:27599751) UniProtKB PMID:27599751 NCBI chrNW_004955499:1,947,337...1,976,847 JBrowse link
G Rock1 Rho associated coiled-coil containing protein kinase 1 ISO (MGI:MGI:6158813|PMID:28679962) ARUK-UCL PMID:28679962 MGI:MGI:6158813, RGD:13601991 NCBI chrNW_004955402:9,752,101...9,864,317 JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 ISO PMID:28679962
(MGI:MGI:6158813|PMID:28679962)
ARUK-UCL PMID:28679962 MGI:MGI:6158813, RGD:13601991 NCBI chrNW_004955487:5,856,190...5,972,408 JBrowse link
G Runx3 RUNX family transcription factor 3 ISO (PMID:20599712) UniProtKB PMID:20599712 NCBI chrNW_004955452:4,580,444...4,606,820 JBrowse link
G Serpine1 serpin family E member 1 ISO RGD PMID:16105028 RGD:8547842 NCBI chrNW_004955456:16,147,523...16,157,040 JBrowse link
G Smad4 SMAD family member 4 ISO (PMID:9707553) UniProtKB PMID:9707553 NCBI chrNW_004955402:35,956,080...36,001,746 JBrowse link
G Zfhx3 zinc finger homeobox 3 ISO (PMID:20599712) UniProtKB PMID:20599712 NCBI chrNW_004955484:5,470,203...5,746,325 JBrowse link
cellular response to transforming growth factor beta stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO RGD PMID:15629889 RGD:8693572 NCBI chrNW_004955513:652,048...799,182 JBrowse link
G Actr3 actin related protein 3 ISO RGD PMID:22319661 RGD:11530045 NCBI chrNW_004955459:15,216,914...15,284,013 JBrowse link
G Acvrl1 activin A receptor like type 1 ISO (PMID:19494318)
(MGI:MGI:3848261|PMID:19494318)
BHF-UCL PMID:19494318 MGI:MGI:3848261 NCBI chrNW_004955547:2,278,548...2,293,865 JBrowse link
G Ankrd1 ankyrin repeat domain 1 ISO (PMID:11139470) BHF-UCL PMID:11139470 NCBI chrNW_004955425:2,258,554...2,267,699 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO RGD PMID:11003619 RGD:2325753 NCBI chrNW_004955405:34,619,780...34,693,616 JBrowse link
G Arg1 arginase 1 ISO RGD PMID:12069499 RGD:634666 NCBI chrNW_004955436:12,235,767...12,247,817 JBrowse link
G Cav1 caveolin 1 ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chrNW_004955432:22,258,262...22,292,403 JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO RGD PMID:20429874 RGD:4889909 NCBI chrNW_004955481:10,293,758...10,301,118 JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B ISO RGD PMID:11369440 RGD:11252200 NCBI chrNW_004955472:12,275,613...12,280,141 JBrowse link
G Cilp cartilage intermediate layer protein ISO (PMID:29167509) BHF-UCL PMID:29167509 NCBI chrNW_004955450:10,231,082...10,244,632 JBrowse link
G Cldn1 claudin 1 ISO RGD PMID:18031476 RGD:11344898 NCBI chrNW_004955420:17,798,974...17,815,049 JBrowse link
G Clec3b C-type lectin domain family 3 member B ISO (PMID:7589422) UniProtKB PMID:7589422 NCBI chrNW_004955420:26,665,472...26,669,474 JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO PMID:19362560 RGD
UniProt
PMID:19362560, PMID:23560091 RGD:8552683, RGD:8554531 NCBI chrNW_004955451:11,468,156...11,484,410 JBrowse link
G Col4a2 collagen type IV alpha 2 chain ISO (PMID:17525254) UniProtKB PMID:17525254 NCBI chrNW_004955404:2,092,184...2,178,079 JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO RGD PMID:21308733 RGD:10059386 NCBI chrNW_004955457:7,424,403...7,490,630 JBrowse link
G Crk CRK proto-oncogene, adaptor protein ISO RGD PMID:12837295 RGD:11568682 NCBI chrNW_004955481:1,705,595...1,748,363 JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein ISO (PMID:23959425) ARUK-UCL PMID:23959425 NCBI chrNW_004955442:19,358,202...19,388,552 JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:12446007 RGD:4892023 NCBI chrNW_004955427:24,691,206...24,705,599 JBrowse link
G Dab2 DAB adaptor protein 2 ISO (MGI:MGI:5442512|PMID:15894542), (MGI:MGI:5442513|PMID:15734730) UniProtKB
RGD
PMID:15734730, PMID:15894542, PMID:21762377 MGI:MGI:5442512, MGI:MGI:5442513, RGD:7243156 NCBI chrNW_004955426:23,852,752...23,883,030 JBrowse link
G Dbn1 drebrin 1 ISO RGD PMID:22319661 RGD:11530045 NCBI chrNW_004955408:29,695,442...29,705,417 JBrowse link
G Dlx1 distal-less homeobox 1 ISO (PMID:14671321) UniProtKB PMID:14671321 NCBI chrNW_004955449:2,920,705...2,924,667 JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO RGD PMID:24211420 RGD:9588224 NCBI chrNW_004955495:1,465,529...1,505,379 JBrowse link
G Edn1 endothelin 1 ISO RGD PMID:8439651 RGD:8662306 NCBI chrNW_004955465:2,287,906...2,314,945 JBrowse link
G Eln elastin ISO RGD PMID:9224206 RGD:9585659 NCBI chrNW_004955456:13,788,992...13,818,836 JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO RGD PMID:24157151 RGD:13204713 NCBI chrNW_004955436:12,416,147...12,477,214 JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 ISO (MGI:MGI:3821807|PMID:18794329) MGI PMID:18794329 MGI:MGI:3821807 NCBI chrNW_004955459:9,641,926...9,783,718 JBrowse link
G Fbn1 fibrillin 1 ISO RGD PMID:11012893 RGD:7387263 NCBI chrNW_004955409:5,281,603...5,502,547 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO RGD PMID:12648559 RGD:12801436 NCBI chrNW_004955551:2,321,190...2,427,000 JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:16669970 RGD:1626090 NCBI chrNW_004955457:629,599...694,948 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chrNW_004955411:36,403,156...36,597,660 JBrowse link
G Hdac2 histone deacetylase 2 ISO RGD PMID:19553350 RGD:9590229 NCBI chrNW_004955526:2,739,099...2,759,640 JBrowse link
G Hyal2 hyaluronidase 2 ISO (PMID:19366691)
(MGI:MGI:3851310|PMID:19366691)
BHF-UCL PMID:19366691 MGI:MGI:3851310 NCBI chrNW_004955532:2,120,781...2,125,083 JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO RGD PMID:16628634 RGD:9686088 NCBI chrNW_004955422:29,337,969...29,339,178 JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO RGD PMID:12837295 RGD:11568682 NCBI chrNW_004955416:26,101,090...26,382,660 JBrowse link
G L1cam L1 cell adhesion molecule ISO RGD PMID:16686695 RGD:6483452 NCBI chrNW_004955580:548,442...561,580 JBrowse link
G Lims1 LIM zinc finger domain containing 1 ISO (PMID:21390327) UniProtKB PMID:21390327 NCBI chrNW_004955470:12,142,997...12,158,273 JBrowse link
G LOC102014960 cholesterol side-chain cleavage enzyme, mitochondrial ISO FSH-stimulated granulosa cells RGD PMID:18511507 RGD:4781450 NCBI chrNW_004955450:3,433,310...3,484,462 JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO (PMID:18588859) UniProtKB PMID:18588859 NCBI chrNW_004955467:381,801...387,078 JBrowse link
G Mef2c myocyte enhancer factor 2C ISO (PMID:9770491) UniProtKB PMID:9770491 NCBI chrNW_004955418:22,537,388...22,701,434 JBrowse link
G Muc4 mucin 4, cell surface associated ISO RGD PMID:9857062 RGD:2324952 NCBI chrNW_004955420:12,228,801...12,274,840 JBrowse link
G Nos3 nitric oxide synthase 3 ISO RGD PMID:21792926 RGD:8662393 NCBI chrNW_004955491:5,438,228...5,457,308 JBrowse link
G Nox4 NADPH oxidase 4 ISO RGD PMID:18845355 RGD:2324663 NCBI chrNW_004955414:4,062,337...4,220,032 JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO (PMID:12902338) CAFA PMID:12902338 NCBI chrNW_004955415:10,494,704...10,585,778 JBrowse link
G Ovol2 ovo like zinc finger 2 ISO (MGI:MGI:6284898|PMID:28455959) ARUK-UCL PMID:28455959 MGI:MGI:6284898 NCBI chrNW_004955415:26,825,284...26,843,438 JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:22073128 RGD:8554355 NCBI chrNW_004955489:520,875...557,609 JBrowse link
G Pdcd5 programmed cell death 5 ISO (PMID:24012345) UniProtKB PMID:24012345 NCBI chrNW_004955468:5,365,137...5,372,888 JBrowse link
G Pde2a phosphodiesterase 2A ISO (PMID:17704206) UniProtKB PMID:17704206 NCBI chrNW_004955414:18,765,591...18,826,717 JBrowse link
G Pde3a phosphodiesterase 3A ISO (PMID:17704206) UniProtKB PMID:17704206 NCBI chrNW_004955413:16,340,827...16,642,731 JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO RGD PMID:16039137 RGD:1581755 NCBI chrNW_004955460:8,328,400...8,346,755 JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:23585135 RGD:9854632 NCBI chrNW_004955412:6,868,995...7,093,353 JBrowse link
G Pdia3 protein disulfide isomerase family A member 3 ISO RGD PMID:15862831 RGD:9999173 NCBI chrNW_004955416:10,197,957...10,221,104 JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:18466611 RGD:2311658 NCBI chrNW_004955478:7,448,584...7,531,860 JBrowse link
G Penk proenkephalin ISO RGD PMID:8584038 RGD:10003035 NCBI chrNW_004955454:15,425,712...15,426,685 JBrowse link
G Postn periostin ISO RGD PMID:22886209 RGD:10040993 NCBI chrNW_004955431:8,510,646...8,544,901 JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO with follicle-stimulating hormone RGD PMID:18511507 RGD:4781450 NCBI chrNW_004955480:543,397...1,188,376 JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent 1A ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chrNW_004955466:9,315,227...9,331,213 JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chrNW_004955461:14,337,914...14,622,779 JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 ISO RGD PMID:23845590 RGD:9835377 NCBI chrNW_004955500:6,655,056...6,674,311 JBrowse link
G Rock1 Rho associated coiled-coil containing protein kinase 1 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chrNW_004955402:9,752,101...9,864,317 JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chrNW_004955487:5,856,190...5,972,408 JBrowse link
G Scx scleraxis bHLH transcription factor ISO (PMID:18498113), (PMID:9328840) UniProtKB PMID:9328840, PMID:18498113 NCBI chrNW_004955454:2,886,981...2,888,829 JBrowse link
G Serpine1 serpin family E member 1 ISO (MGI:MGI:5289760|PMID:21829547) MGI
RGD
PMID:19247458, PMID:21829547 MGI:MGI:5289760, RGD:8547745 NCBI chrNW_004955456:16,147,523...16,157,040 JBrowse link
G Sfrp1 secreted frizzled related protein 1 ISO (PMID:16149051) UniProtKB PMID:16149051 NCBI chrNW_004955536:1,663,721...1,702,678 JBrowse link
G Smad3 SMAD family member 3 ISO (PMID:12902338) CAFA PMID:12902338 NCBI chrNW_004955450:8,747,651...8,842,003 JBrowse link
G Smad7 SMAD family member 7 ISO (MGI:MGI:5532916|PMID:18593713)
(PMID:18593713)
BHF-UCL PMID:18593713 MGI:MGI:5532916 NCBI chrNW_004955402:34,028,184...34,058,949 JBrowse link
G Snrnp70 small nuclear ribonucleoprotein U1 subunit 70 ISO RGD PMID:10022522 RGD:10448942 NCBI chrNW_004955559:1,618,246...1,634,144 JBrowse link
G Sox5 SRY-box transcription factor 5 ISO (PMID:21401405) UniProtKB PMID:21401405 NCBI chrNW_004955413:18,831,931...19,676,371 JBrowse link
G Sox6 SRY-box transcription factor 6 ISO (PMID:21401405) UniProtKB PMID:21401405 NCBI chrNW_004955414:30,965,626...31,532,473 JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (PMID:21401405)
(PMID:17525254)
UniProtKB PMID:17525254, PMID:21401405 NCBI chrNW_004955478:941,684...945,563 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chrNW_004955445:19,213,210...19,227,670 JBrowse link
G Star steroidogenic acute regulatory protein ISO FSH-stimulated granulosa cells RGD PMID:18511507 RGD:4781450 NCBI chrNW_004955463:13,760,089...13,765,245 JBrowse link
G Stk16 serine/threonine kinase 16 ISO RGD PMID:10947953 RGD:727297 NCBI chrNW_004955453:14,182,167...14,185,569 JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO (MGI:MGI:5532214|PMID:23861879)
(PMID:22269326)
(PMID:19736306), (PMID:22269326)
MGI
BHF-UCL
PMID:19736306, PMID:22269326, PMID:23861879 MGI:MGI:5532214 NCBI chrNW_004955555:274,405...288,441 JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 ISO (PMID:19494318)
(MGI:MGI:3848261|PMID:19494318)
BHF-UCL PMID:19494318 MGI:MGI:3848261 NCBI chrNW_004955419:26,490,899...26,546,349 JBrowse link
G Usp9x ubiquitin specific peptidase 9 X-linked ISO (MGI:MGI:5532214|PMID:23861879) MGI PMID:23861879 MGI:MGI:5532214 NCBI chrNW_004955565:1,479,040...1,602,070 JBrowse link
G Wnt10a Wnt family member 10A ISO (PMID:15040835) UniProtKB PMID:15040835 NCBI chrNW_004955453:14,528,373...14,540,801 JBrowse link
G Wnt2 Wnt family member 2 ISO (PMID:15040835) UniProtKB PMID:15040835 NCBI chrNW_004955432:22,988,208...23,024,530 JBrowse link
G Wnt4 Wnt family member 4 ISO (PMID:15040835) UniProtKB PMID:15040835 NCBI chrNW_004955452:2,319,446...2,344,740 JBrowse link
G Wnt5a Wnt family member 5A ISO (PMID:15040835) UniProtKB PMID:15040835 NCBI chrNW_004955430:5,304,817...5,325,684 JBrowse link
G Wnt7a Wnt family member 7A ISO (PMID:15040835) UniProtKB PMID:15040835 NCBI chrNW_004955429:12,647,993...12,693,998 JBrowse link
G Wwox WW domain containing oxidoreductase ISO (MGI:MGI:3851310|PMID:19366691)
(PMID:19366691)
BHF-UCL PMID:19366691 MGI:MGI:3851310 NCBI chrNW_004955522:1,265,732...2,185,372 JBrowse link
G Xcl1 X-C motif chemokine ligand 1 ISO (MGI:MGI:85739|PMID:9013979) BHF-UCL PMID:9013979 MGI:MGI:85739 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
G Yes1 YES proto-oncogene 1, Src family tyrosine kinase ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chrNW_004955402:9,199,704...9,255,183 JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 ISO RGD PMID:16824956 RGD:2325877 NCBI chrNW_004955429:23,011,627...23,198,188 JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 ISO (PMID:20166898) UniProtKB PMID:20166898 NCBI chrNW_004955466:1,541,367...1,546,617 JBrowse link
G Zfp36l2 ZFP36 ring finger protein like 2 ISO (PMID:20166898) UniProtKB PMID:20166898 NCBI chrNW_004955441:10,467,608...10,469,885 JBrowse link
negative regulation of cellular response to transforming growth factor beta stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cflar CASP8 and FADD like apoptosis regulator ISO RGD PMID:18314484 RGD:11341711 NCBI chrNW_004955403:415,092...442,214 JBrowse link
G Dlx1 distal-less homeobox 1 ISO (PMID:14671321) UniProtKB PMID:14671321 NCBI chrNW_004955449:2,920,705...2,924,667 JBrowse link
G Il4 interleukin 4 ISO (PMID:11967989) UniProt PMID:11967989 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
negative regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO (PMID:21170088) UniProtKB PMID:21170088 NCBI chrNW_004955487:5,180,241...5,218,298 JBrowse link
G Adamtsl2 ADAMTS like 2 ISO (PMID:18677313)
(MGI:MGI:5638958|PMID:25762570)
BHF-UCL
MGI
PMID:18677313, PMID:25762570 MGI:MGI:5638958 NCBI chrNW_004955513:2,849,310...2,879,130 JBrowse link
G Aspn asporin ISO (MGI:MGI:3762064|PMID:17827158)
(PMID:17827158)
UniProtKB PMID:17827158 MGI:MGI:3762064 NCBI chrNW_004955515:5,322,074...5,345,715 JBrowse link
G Bambi BMP and activin membrane bound inhibitor ISO (PMID:14660579)
(PMID:19328798)
BHF-UCL PMID:14660579, PMID:19328798 NCBI chrNW_004955429:21,024,396...21,025,890 JBrowse link
G Bcl9l BCL9 like ISO (PMID:19328798) BHF-UCL PMID:19328798 NCBI chrNW_004955412:20,029,988...20,059,057 JBrowse link
G Cav1 caveolin 1 ISO (PMID:25893292) UniProtKB PMID:25893292 NCBI chrNW_004955432:22,258,262...22,292,403 JBrowse link
G Cav2 caveolin 2 ISO (MGI:MGI:5298182|PMID:21832243) MGI PMID:21832243 MGI:MGI:5298182 NCBI chrNW_004955432:22,240,041...22,242,200 JBrowse link
G Cd109 CD109 molecule ISO (PMID:16754747) UniProtKB PMID:16754747 NCBI chrNW_004955488:9,281,407...9,378,354 JBrowse link
G Chst11 carbohydrate sulfotransferase 11 ISO (MGI:MGI:3767479|PMID:16079159) MGI PMID:16079159 MGI:MGI:3767479 NCBI chrNW_004955405:38,985,046...39,134,130 JBrowse link
G Cidea cell death inducing DFFA like effector a ISO (MGI:MGI:3768618|PMID:17080483) BHF-UCL PMID:17080483 MGI:MGI:3768618 NCBI chrNW_004955402:1,090,372...1,096,621 JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 ISO (MGI:MGI:3055566|PMID:14721776) MGI PMID:14721776 MGI:MGI:3055566 NCBI chrNW_004955415:32,012,637...32,015,965 JBrowse link
G Dnm2 dynamin 2 ISO RGD PMID:25100282 RGD:9685289 NCBI chrNW_004955495:1,860,644...1,934,589 JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 ISO (PMID:14612439) HGNC PMID:14612439 NCBI chrNW_004955468:29,927...32,947 JBrowse link
G Emilin1 elastin microfibril interfacer 1 ISO (MGI:MGI:5605894|PMID:25056700) BHF-UCL PMID:25056700 MGI:MGI:5605894 NCBI chrNW_004955469:9,049,666...9,057,692 JBrowse link
G Fam89b family with sequence similarity 89 member B ISO (MGI:MGI:5486566|PMID:12646588) UniProtKB PMID:12646588 MGI:MGI:5486566 NCBI chrNW_004955422:19,690,806...19,693,575 JBrowse link
G Glg1 golgi glycoprotein 1 ISO (MGI:MGI:4829577|PMID:20530870) MGI PMID:20530870 MGI:MGI:4829577 NCBI chrNW_004955484:2,871,390...2,987,913 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO (MGI:MGI:3771280|PMID:17991893) MGI PMID:17991893 MGI:MGI:3771280 NCBI chrNW_004955419:3,055,420...3,060,208 JBrowse link
G Htra1 HtrA serine peptidase 1 ISO (MGI:MGI:3034116|PMID:14973287) MGI PMID:14973287 MGI:MGI:3034116 NCBI chrNW_004955477:761,127...808,396 JBrowse link
G Htra3 HtrA serine peptidase 3 ISO (MGI:MGI:3046453|PMID:15206957) UniProtKB PMID:15206957 MGI:MGI:3046453 NCBI chrNW_004955514:2,716,448...2,740,590 JBrowse link
G Il17rd interleukin 17 receptor D ISO (MGI:MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:MGI:6414689 NCBI chrNW_004955430:6,842,756...6,873,195 JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 ISO (MGI:MGI:5583005|PMID:24627487)
(PMID:24627487)
UniProtKB PMID:24627487 MGI:MGI:5583005 NCBI chrNW_004955402:384,177...508,876 JBrowse link
G Mecom MDS1 and EVI1 complex locus NOT ISO (PMID:15897867) UniProt PMID:15897867 NCBI chrNW_004955448:18,259,847...18,542,085 JBrowse link
G Nkx2-1 NK2 homeobox 1 ISO (PMID:19293183) UniProtKB PMID:19293183 NCBI chrNW_004955409:24,612,490...24,616,360 JBrowse link
G Onecut1 one cut homeobox 1 ISO (MGI:MGI:3588024|PMID:16103213) MGI PMID:16103213 MGI:MGI:3588024 NCBI chrNW_004955409:2,181,364...2,214,636 JBrowse link
G Onecut2 one cut homeobox 2 ISO (MGI:MGI:3588024|PMID:16103213) MGI PMID:16103213 MGI:MGI:3588024 NCBI chrNW_004955402:41,782,281...41,839,782 JBrowse link
G Pbld phenazine biosynthesis like protein domain containing ISO (PMID:23687415) UniProtKB PMID:23687415 NCBI chrNW_004955425:20,564,296...20,620,988 JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 ISO (PMID:17327236) UniProtKB PMID:17327236 NCBI chrNW_004955442:14,685,089...14,772,870 JBrowse link
G Peg10 paternally expressed 10 ISO (PMID:15611116) HGNC PMID:15611116 NCBI chrNW_004955432:11,383,919...11,395,313 JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO (PMID:19122240) BHF-UCL PMID:19122240 NCBI chrNW_004955495:1,250,557...1,261,617 JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 ISO (MGI:MGI:5582164|PMID:20129061)
(PMID:24627487)
(PMID:20129061)
UniProtKB PMID:20129061, PMID:24627487 MGI:MGI:5582164 NCBI chrNW_004955445:1,837,084...1,847,214 JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent 1A ISO (PMID:16751101) UniProtKB PMID:16751101 NCBI chrNW_004955466:9,315,227...9,331,213 JBrowse link
G Prdm16 PR/SET domain 16 NOT ISO (PMID:14656887)
(MGI:MGI:4430027|PMID:20007998)
(PMID:19049980)
UniProtKB
MGI
PMID:14656887, PMID:19049980, PMID:20007998 MGI:MGI:4430027 NCBI chrNW_004955486:8,139,848...8,327,788 JBrowse link
G Rasl11b RAS like family 11 member B ISO (MGI:MGI:3505646|PMID:15239668) MGI PMID:15239668 MGI:MGI:3505646 NCBI chrNW_004955447:17,755,277...17,758,827 JBrowse link
G Sirt1 sirtuin 1 ISO (MGI:MGI:5306300|PMID:17098745) UniProtKB PMID:17098745 MGI:MGI:5306300 NCBI chrNW_004955425:20,280,725...20,307,663 JBrowse link
G Ski SKI proto-oncogene ISO (PMID:17054724), (PMID:19049980)
(MGI:MGI:5300220|PMID:21937600)
(PMID:15312649)
(PMID:17469184)
UniProtKB
MGI
PMID:15312649, PMID:17054724, PMID:17469184, PMID:19049980, PMID:21937600 MGI:MGI:5300220 NCBI chrNW_004955486:8,857,693...8,921,821 JBrowse link
G Skil SKI like proto-oncogene ISO (MGI:MGI:3530729|PMID:15677329)
(PMID:17469184), (PMID:19383336)
MGI
UniProtKB
PMID:15677329, PMID:17469184, PMID:19383336 MGI:MGI:3530729 NCBI chrNW_004955420:530,531...554,308 JBrowse link
G Skor2 SKI family transcriptional corepressor 2 NOT ISO (MGI:MGI:5300220|PMID:21937600)
(PMID:16200078)
MGI
UniProtKB
PMID:16200078, PMID:21937600 MGI:MGI:5300220 NCBI chrNW_004955402:32,577,189...32,618,611 JBrowse link
G Slc2a10 solute carrier family 2 member 10 ISO (PMID:16550171), (PMID:26376865) ARUK-UCL PMID:16550171, PMID:26376865 NCBI chrNW_004955445:10,708,147...10,722,109 JBrowse link
G Smad6 SMAD family member 6 ISO (PMID:9256479)
(PMID:19047146)
BHF-UCL PMID:9256479, PMID:19047146 NCBI chrNW_004955450:9,005,332...9,070,790 JBrowse link
G Smad7 SMAD family member 7 ISO (PMID:12151385), (PMID:17438144), (PMID:18762808), (PMID:9256479) BHF-UCL PMID:9256479, PMID:12151385, PMID:17438144, PMID:18762808 NCBI chrNW_004955402:34,028,184...34,058,949 JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO (PMID:11278251), (PMID:12151385) BHF-UCL PMID:11278251, PMID:12151385 NCBI chrNW_004955460:14,774,545...14,860,783 JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 ISO (PMID:19255252) CACAO PMID:19255252 NCBI chrNW_004955478:7,205,266...7,336,390 JBrowse link
G Snx1 sorting nexin 1 ISO (MGI:MGI:3505646|PMID:15239668) MGI PMID:15239668 MGI:MGI:3505646 NCBI chrNW_004955450:11,266,712...11,306,014 JBrowse link
G Snx25 sorting nexin 25 ISO (MGI:MGI:5545984|PMID:21266196)
(PMID:21266196)
UniProtKB PMID:21266196 MGI:MGI:5545984 NCBI chrNW_004955403:23,678,301...23,787,256 JBrowse link
G Snx6 sorting nexin 6 ISO (PMID:11279102) HGNC PMID:11279102 NCBI chrNW_004955409:26,323,940...26,353,675 JBrowse link
G Spred1 sprouty related EVH1 domain containing 1 ISO (MGI:MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:MGI:6414689 NCBI chrNW_004955416:5,288,779...5,376,861 JBrowse link
G Spred2 sprouty related EVH1 domain containing 2 ISO (MGI:MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:MGI:6414689 NCBI chrNW_004955424:19,133,568...19,250,118 JBrowse link
G Spred3 sprouty related EVH1 domain containing 3 ISO (MGI:MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:MGI:6414689 NCBI chrNW_004955468:1,030,964...1,039,495 JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 ISO (MGI:MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:MGI:6414689 NCBI chrNW_004955428:17,451,703...17,455,695 JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 ISO (MGI:MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:MGI:6414689 NCBI chrNW_004955404:27,349,286...27,353,706 JBrowse link
G Strap serine/threonine kinase receptor associated protein ISO (PMID:23687415)
(MGI:MGI:1321347|PMID:9856985)
UniProtKB
MGI
PMID:9856985, PMID:23687415 MGI:MGI:1321347 NCBI chrNW_004955413:12,533,422...12,558,138 JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 ISO (PMID:24613385) UniProtKB PMID:24613385 NCBI chrNW_004955442:16,521,130...16,523,733 JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 ISO (MGI:MGI:3771280|PMID:17991893) MGI PMID:17991893 MGI:MGI:3771280 NCBI chrNW_004955420:25,476,975...25,479,969 JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 ISO (PMID:18762808) BHF-UCL PMID:18762808 NCBI chrNW_004955493:8,309,480...8,315,378 JBrowse link
G Tgfb3 transforming growth factor beta 3 ISO RGD PMID:12071374 RGD:730235 NCBI chrNW_004955438:33,129...55,180 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO RGD PMID:10746731 RGD:1579946 NCBI chrNW_004955423:2,573,851...2,765,353 JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:3528807|PMID:15657445) MGI PMID:15657445 MGI:MGI:3528807 NCBI chrNW_004955467:9,241,391...9,256,716 JBrowse link
G Vasn vasorin ISO (PMID:21170088)
(PMID:15247411)
UniProtKB PMID:15247411, PMID:21170088 NCBI chrNW_004955442:13,060,923...13,071,303 JBrowse link
G Veph1 ventricular zone expressed PH domain containing 1 ISO (PMID:26039994) UniProt PMID:26039994 NCBI chrNW_004955448:8,207,272...8,423,712 JBrowse link
G Wfikkn1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 ISO (PMID:21054789) UniProtKB PMID:21054789 NCBI chrNW_004955442:16,573,094...16,577,650 JBrowse link
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 ISO (PMID:21054789) UniProtKB PMID:21054789 NCBI chrNW_004955451:10,976,748...10,982,482 JBrowse link
G Wnt1 Wnt family member 1 ISO (MGI:MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:MGI:3628833 NCBI chrNW_004955500:7,797,063...7,811,142 JBrowse link
G Xbp1 X-box binding protein 1 ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7A ISO (PMID:25514493) UniProt PMID:25514493 NCBI chrNW_004955495:4,747,905...4,754,066 JBrowse link
G Znf451 zinc finger protein 451 ISO (PMID:24324267) UniProtKB PMID:24324267 NCBI chrNW_004955502:3,003,822...3,087,529 JBrowse link
positive regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO (MGI:MGI:3829110|PMID:18625725) BHF-UCL PMID:18625725 MGI:MGI:3829110 NCBI chrNW_004955487:5,180,241...5,218,298 JBrowse link
G Axin1 axin 1 ISO (MGI:MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:MGI:3628833 NCBI chrNW_004955442:16,845,728...16,898,301 JBrowse link
G Cdkn1c cyclin dependent kinase inhibitor 1C ISO (PMID:16943770) BHF-UCL PMID:16943770 NCBI chrNW_004955422:14,576,971...14,578,868 JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B ISO (PMID:16943770) BHF-UCL PMID:16943770 NCBI chrNW_004955472:12,275,613...12,280,141 JBrowse link
G Cited2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO (MGI:MGI:3690196|PMID:16619037) UniProtKB PMID:16619037 MGI:MGI:3690196 NCBI chrNW_004955436:20,370,950...20,372,677 JBrowse link
G Crebbp CREB binding protein ISO (PMID:25514493) UniProt PMID:25514493 NCBI chrNW_004955442:13,559,496...13,691,913 JBrowse link
G Ep300 E1A binding protein p300 ISO (PMID:25514493) UniProt PMID:25514493 NCBI chrNW_004955413:26,647,553...26,727,875 JBrowse link
G Fermt1 fermitin family member 1 ISO (MGI:MGI:5571208|PMID:24681597) CAFA PMID:24681597 MGI:MGI:5571208 NCBI chrNW_004955415:16,447,921...16,483,221 JBrowse link
G Flcn folliculin ISO (PMID:20573232)
(MGI:MGI:5050037|PMID:21258407)
UniProtKB
MGI
PMID:20573232, PMID:21258407 MGI:MGI:5050037 NCBI chrNW_004955577:672,774...694,140 JBrowse link
G Furin furin, paired basic amino acid cleaving enzyme ISO RGD PMID:15194465 RGD:1582619 NCBI chrNW_004955416:14,915,031...14,947,634 JBrowse link
G Gipc1 GIPC PDZ domain containing family member 1 ISO (MGI:MGI:3807767|PMID:11546783) BHF-UCL PMID:11546783 MGI:MGI:3807767 NCBI chrNW_004955415:33,067,689...33,077,749 JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:26880260 RGD:13504840 NCBI chrNW_004955507:5,346,937...5,370,072 JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 ISO (PMID:14678985) UniProtKB PMID:14678985 NCBI chrNW_004955494:3,365,826...3,554,735 JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO (PMID:24613385) UniProtKB PMID:24613385 NCBI chrNW_004955437:9,872,649...9,878,459 JBrowse link
G Ing2 inhibitor of growth family member 2 ISO (PMID:18334480) UniProtKB PMID:18334480 NCBI chrNW_004955403:25,325,600...25,331,175 JBrowse link
G Itga8 integrin subunit alpha 8 ISO (MGI:MGI:3714574|PMID:17537792) MGI PMID:17537792 MGI:MGI:3714574 NCBI chrNW_004955429:11,932,764...12,120,757 JBrowse link
G Lrg1 leucine rich alpha-2-glycoprotein 1 ISO (MGI:MGI:5543310|PMID:23868260) MGI PMID:23868260 MGI:MGI:5543310 NCBI chrNW_004955495:4,402,670...4,405,666 JBrowse link
G Men1 menin 1 ISO (PMID:11274402) UniProtKB PMID:11274402 NCBI chrNW_004955422:20,356,491...20,363,374 JBrowse link
G Myocd myocardin ISO (MGI:MGI:3696631|PMID:16224064) BHF-UCL PMID:16224064 MGI:MGI:3696631 NCBI chrNW_004955467:4,653,065...4,743,438 JBrowse link
G Npnt nephronectin ISO (MGI:MGI:3714574|PMID:17537792) MGI PMID:17537792 MGI:MGI:3714574 NCBI chrNW_004955496:3,321,310...3,388,625 JBrowse link
G Rnf111 ring finger protein 111 ISO (MGI:MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:MGI:3628833 NCBI chrNW_004955450:15,590,053...15,651,344 JBrowse link
G Sdcbp syndecan binding protein ISO (PMID:25893292) UniProtKB PMID:25893292 NCBI chrNW_004955454:17,093,930...17,113,491 JBrowse link
G Slc2a10 solute carrier family 2 member 10 ISO (PMID:26376865) ARUK-UCL PMID:26376865 NCBI chrNW_004955445:10,708,147...10,722,109 JBrowse link
G Smad4 SMAD family member 4 ISO (PMID:19328798) BHF-UCL PMID:19328798 NCBI chrNW_004955402:35,956,080...36,001,746 JBrowse link
G Snw1 SNW domain containing 1 ISO (PMID:11278756) UniProtKB PMID:11278756 NCBI chrNW_004955438:1,561,562...1,601,492 JBrowse link
G Stk11 serine/threonine kinase 11 ISO (PMID:18311138)
(MGI:MGI:3788958|PMID:18311138)
BHF-UCL PMID:18311138 MGI:MGI:3788958 NCBI chrNW_004955495:6,678,195...6,699,408 JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 ISO (PMID:18762808) BHF-UCL PMID:18762808 NCBI chrNW_004955493:8,309,480...8,315,378 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO (MGI:MGI:5617089|PMID:25382630) MGI
RGD
PMID:8106553, PMID:25382630 MGI:MGI:5617089, RGD:1579949 NCBI chrNW_004955423:2,573,851...2,765,353 JBrowse link
G Thbs1 thrombospondin 1 ISO (PMID:18555217)
(MGI:MGI:1270011|PMID:9657149)
BHF-UCL PMID:9657149, PMID:18555217 MGI:MGI:1270011 NCBI chrNW_004955416:6,490,034...6,506,419 JBrowse link
regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl9 BCL9 transcription coactivator NOT ISO (PMID:19328798) BHF-UCL PMID:19328798 NCBI chrNW_004955568:785,361...866,986 JBrowse link
G Cav3 caveolin 3 ISO (MGI:MGI:4946902|PMID:21182936) MGI PMID:21182936 MGI:MGI:4946902 NCBI chrNW_004955561:326,008...335,911 JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 ISO (MGI:MGI:1335654|PMID:10208746) MGI PMID:10208746 MGI:MGI:1335654 NCBI chrNW_004955415:32,012,637...32,015,965 JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 ISO (PMID:14612439) HGNC PMID:14612439 NCBI chrNW_004955468:29,927...32,947 JBrowse link
G Eng endoglin ISO (PMID:15702480) HGNC
RGD
PMID:15702480, PMID:17376778 RGD:2313627 NCBI chrNW_004955419:818,797...853,319 JBrowse link
G Folr1 folate receptor alpha ISO (MGI:MGI:5644149|PMID:21649587) BHF-UCL PMID:21649587 MGI:MGI:5644149 NCBI chrNW_004955414:19,188,830...19,197,728 JBrowse link
G Gdf2 growth differentiation factor 2 NOT ISO (MGI:MGI:4830635|PMID:20406889) DFLAT PMID:20406889 MGI:MGI:4830635 NCBI chrNW_004955556:2,204,841...2,210,335 JBrowse link
G Il17f interleukin 17F ISO (PMID:11591732) UniProtKB PMID:11591732 NCBI chrNW_004955411:5,852,767...5,859,208 JBrowse link
G Itga3 integrin subunit alpha 3 ISO (PMID:24621570) UniProtKB PMID:24621570 NCBI chrNW_004955451:11,563,120...11,590,119 JBrowse link
G Lox lysyl oxidase ISO (MGI:MGI:5634219|PMID:25715398) MGI PMID:25715398 MGI:MGI:5634219 NCBI chrNW_004955521:178,290...193,926 JBrowse link
G Nrep neuronal regeneration related protein ISO (MGI:MGI:3034115|PMID:14985127) MGI PMID:14985127 MGI:MGI:3034115 NCBI chrNW_004955418:3,435,784...3,464,667 JBrowse link
G Smad2 SMAD family member 2 ISO (PMID:14555988) BHF-UCL PMID:14555988 NCBI chrNW_004955402:33,131,760...33,217,144 JBrowse link
G Smad3 SMAD family member 3 ISO (MGI:MGI:2153314|PMID:11711431)
(PMID:8774881)
MGI
BHF-UCL
PMID:8774881, PMID:11711431 MGI:MGI:2153314 NCBI chrNW_004955450:8,747,651...8,842,003 JBrowse link
G Smad4 SMAD family member 4 ISO (PMID:8774881) BHF-UCL PMID:8774881 NCBI chrNW_004955402:35,956,080...36,001,746 JBrowse link
G Smad7 SMAD family member 7 ISO RGD PMID:11959632 RGD:625758 NCBI chrNW_004955402:34,028,184...34,058,949 JBrowse link
G Sox11 SRY-box transcription factor 11 ISO (PMID:20624318) UniProtKB PMID:20624318 NCBI chrNW_004955487:2,678,961...2,680,869 JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO (PMID:15334054) BHF-UCL PMID:15334054 NCBI chrNW_004955555:274,405...288,441 JBrowse link
G Trim33 tripartite motif containing 33 ISO (PMID:19135894) UniProtKB PMID:19135894 NCBI chrNW_004955435:17,631,596...17,750,261 JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 ISO (MGI:MGI:3641341|PMID:16824956) MGI PMID:16824956 MGI:MGI:3641341 NCBI chrNW_004955429:23,011,627...23,198,188 JBrowse link
G Znf703 zinc finger protein 703 ISO (PMID:21337521)
(MGI:MGI:4940410|PMID:21317240)
UniProtKB PMID:21317240, PMID:21337521 MGI:MGI:4940410 NCBI chrNW_004955463:13,407,491...13,411,562 JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbn1 fibrillin 1 ISO (MGI:MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:MGI:4836762 NCBI chrNW_004955409:5,281,603...5,502,547 JBrowse link
G Fbn2 fibrillin 2 ISO (MGI:MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:MGI:4836762 NCBI chrNW_004955415:1,307,553...1,535,435 JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 ISO (PMID:2022183), (PMID:8617200) UniProt PMID:2022183, PMID:8617200 NCBI chrNW_004955441:1,405,340...1,626,668 JBrowse link
G Nrros negative regulator of reactive oxygen species ISO (MGI:MGI:6192878|PMID:29909984) UniProt PMID:29909984 MGI:MGI:6192878 NCBI chrNW_004955420:12,792,173...12,798,645 JBrowse link
transforming growth factor beta receptor complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor type 1C ISO TbetaR-II, ActR-II (Chlorocebus aethiops), ligand-dependent RGD PMID:8940033 RGD:631880 NCBI chrNW_004955449:15,814,230...15,864,747 JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 ISO (PMID:14612439) HGNC PMID:14612439 NCBI chrNW_004955468:29,927...32,947 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO RGD PMID:8106553 RGD:1579949 NCBI chrNW_004955423:2,573,851...2,765,353 JBrowse link
transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 ISO (MGI:MGI:1935017|PMID:11376112)
(PMID:8242742)
PMID:12968668
MGI
UniProtKB
UniProt
PMID:8242742, PMID:11376112, PMID:12968668 MGI:MGI:1935017, RGD:8554636 NCBI chrNW_004955449:15,587,958...15,706,432 JBrowse link
G Acvrl1 activin A receptor like type 1 ISO (PMID:15702480)
(MGI:MGI:2679137|PMID:14580334)
HGNC
MGI
PMID:14580334, PMID:15702480 MGI:MGI:2679137 NCBI chrNW_004955547:2,278,548...2,293,865 JBrowse link
G Adam9 ADAM metallopeptidase domain 9 ISO (MGI:MGI:3828410|PMID:11955914)
(PMID:11955914)
BHF-UCL PMID:11955914 MGI:MGI:3828410 NCBI chrNW_004955463:14,545,425...14,646,498 JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 ISO PMID:11376112 MGI PMID:11376112 RGD:8554753 NCBI chrNW_004955458:693,434...703,026 JBrowse link
G Apoa1 apolipoprotein A1 NOT ISO (PMID:23726972) UniProtKB PMID:23726972 NCBI chrNW_004955412:18,170,331...18,172,298 JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 ISO (PMID:26583432) UniProt PMID:26583432 NCBI chrNW_004955430:6,986,977...7,018,938 JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 ISO (PMID:26583432) UniProt PMID:26583432 NCBI chrNW_004955405:39,503,020...39,540,069 JBrowse link
G Arrb2 arrestin beta 2 ISO (PMID:12958365) BHF-UCL PMID:12958365 NCBI chrNW_004955467:10,109,985...10,118,687 JBrowse link
G Bambi BMP and activin membrane bound inhibitor ISO RGD PMID:12933693 RGD:632261 NCBI chrNW_004955429:21,024,396...21,025,890 JBrowse link
G Cdh5 cadherin 5 ISO (PMID:21168935) UniProtKB PMID:21168935 NCBI chrNW_004955433:22,957,718...22,994,515 JBrowse link
G Cited1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 ISO (PMID:9707553) BHF-UCL PMID:9707553 NCBI chrNW_004955475:11,722,514...11,725,067 JBrowse link
G Cited2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO (MGI:MGI:3690196|PMID:16619037) MGI PMID:16619037 MGI:MGI:3690196 NCBI chrNW_004955436:20,370,950...20,372,677 JBrowse link
G Cldn5 claudin 5 ISO (PMID:21168935) UniProtKB PMID:21168935 NCBI chrNW_004955442:18,509,501...18,511,267 JBrowse link
G Col1a2 collagen type I alpha 2 chain ISO (PMID:17217948) UniProtKB PMID:17217948 NCBI chrNW_004955432:11,127,961...11,164,145 JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO (PMID:16360482) UniProtKB PMID:16360482 NCBI chrNW_004955403:9,720,831...9,758,019 JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO RGD PMID:16891311 RGD:1625706 NCBI chrNW_004955457:7,424,403...7,490,630 JBrowse link
G Dusp22 dual specificity phosphatase 22 ISO (MGI:MGI:2387732|PMID:12138158) MGI PMID:12138158 MGI:MGI:2387732 NCBI chrNW_004955465:12,551,063...12,597,386 JBrowse link
G Eng endoglin NOT ISO (PMID:12015308), (PMID:18223685)
(PMID:8294451)
(PMID:18223685)
BHF-UCL PMID:8294451, PMID:12015308, PMID:18223685 NCBI chrNW_004955419:818,797...853,319 JBrowse link
G Fermt2 fermitin family member 2 ISO (PMID:21325030) UniProtKB PMID:21325030 NCBI chrNW_004955409:10,285,780...10,327,286 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO (PMID:9732876) BHF-UCL PMID:9732876 NCBI chrNW_004955523:307,181...310,728 JBrowse link
G Foxh1 forkhead box H1 ISO (MGI:MGI:1328655|PMID:10349617), (MGI:MGI:3055632|PMID:15363409)
(MGI:MGI:1321467|PMID:9858566)
BHF-UCL PMID:9858566, PMID:10349617, PMID:15363409 MGI:MGI:1321467, MGI:MGI:1328655, MGI:MGI:3055632 NCBI chrNW_004955454:3,094,015...3,096,060 JBrowse link
G Fshb follicle stimulating hormone subunit beta ISO (PMID:14557487) BHF-UCL PMID:14557487 NCBI chrNW_004955476:8,795,354...8,797,244 JBrowse link
G Fut8 fucosyltransferase 8 ISO (MGI:MGI:3608245|PMID:16236725) MGI PMID:16236725 MGI:MGI:3608245 NCBI chrNW_004955466:4,248,414...4,481,942 JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 ISO (MGI:MGI:3696537|PMID:17159989) MGI PMID:17159989 MGI:MGI:3696537 NCBI chrNW_004955494:3,365,826...3,554,735 JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase ISO (PMID:15574495) UniProtKB PMID:15574495 NCBI chrNW_004955403:32,569,841...32,614,860 JBrowse link
G Itgb1 integrin subunit beta 1 NOT ISO (PMID:24036928)
(MGI:MGI:5582864|PMID:24036928)
UniProtKB PMID:24036928 MGI:MGI:5582864 NCBI chrNW_004955462:4,454,809...4,483,227 JBrowse link
G Itgb5 integrin subunit beta 5 ISO (MGI:MGI:5582864|PMID:24036928)
(PMID:24036928)
UniProtKB PMID:24036928 MGI:MGI:5582864 NCBI chrNW_004955427:23,851,475...23,952,211 JBrowse link
G Itgb6 integrin subunit beta 6 ISO (MGI:MGI:6376388|PMID:30952606)
(MGI:MGI:3040752|PMID:12634787)
MGI PMID:12634787, PMID:30952606 MGI:MGI:3040752, MGI:MGI:6376388 NCBI chrNW_004955449:13,387,013...13,520,879 JBrowse link
G Itgb8 integrin subunit beta 8 ISO (MGI:MGI:6376388|PMID:30952606) MGI PMID:30952606 MGI:MGI:6376388 NCBI chrNW_004955410:23,011,874...23,099,191 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO (PMID:9732876) BHF-UCL PMID:9732876 NCBI chrNW_004955464:1,107,598...1,110,326 JBrowse link
G Lrrc32 leucine rich repeat containing 32 ISO (PMID:19750484) UniProt PMID:19750484 NCBI chrNW_004955414:15,296,704...15,309,088 JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 ISO (MGI:MGI:72661|PMID:7730318)
(MGI:MGI:2389565|PMID:12379497)
MGI PMID:7730318, PMID:12379497 MGI:MGI:2389565, MGI:MGI:72661 NCBI chrNW_004955422:19,714,161...19,730,344 JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 ISO (MGI:MGI:2386340|PMID:12208849) MGI PMID:12208849 MGI:MGI:2386340 NCBI chrNW_004955578:685,960...712,809 JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO (MGI:MGI:2674169|PMID:12941696) MGI PMID:12941696 MGI:MGI:2674169 NCBI chrNW_004955446:11,022,091...11,090,136 JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 ISO (MGI:MGI:3607216|PMID:16145668) MGI PMID:16145668 MGI:MGI:3607216 NCBI chrNW_004955411:17,177,335...17,229,957 JBrowse link
G Mstn myostatin ISO (MGI:MGI:2676508|PMID:12595574) MGI PMID:12595574 MGI:MGI:2676508 NCBI chrNW_004955403:8,914,505...8,921,190 JBrowse link
G Nlk nemo like kinase ISO (PMID:15004007) UniProtKB PMID:15004007 NCBI chrNW_004955481:4,828,441...4,973,734 JBrowse link
G Nrros negative regulator of reactive oxygen species ISO (MGI:MGI:6192878|PMID:29909984) UniProt PMID:29909984 MGI:MGI:6192878 NCBI chrNW_004955420:12,792,173...12,798,645 JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO PMID:22073128 BHF-UCL PMID:22073128 RGD:8554355 NCBI chrNW_004955489:520,875...557,609 JBrowse link
G Pias2 protein inhibitor of activated STAT 2 NOT ISO (PMID:16777850) UniProt PMID:16777850 NCBI chrNW_004955402:32,263,616...32,358,532 JBrowse link
G Pml PML nuclear body scaffold ISO (MGI:MGI:3054278|PMID:15356634) MGI PMID:15356634 MGI:MGI:3054278 NCBI chrNW_004955450:3,654,854...3,692,057 JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO (PMID:24036928) UniProtKB PMID:24036928 NCBI chrNW_004955461:14,337,914...14,622,779 JBrowse link
G Ptprk protein tyrosine phosphatase receptor type K ISO (PMID:15899872) UniProtKB PMID:15899872 NCBI chrNW_004955436:8,975,742...9,371,608 JBrowse link
G Pxn paxillin ISO (MGI:MGI:5582864|PMID:24036928)
(PMID:24036928)
UniProtKB PMID:24036928 MGI:MGI:5582864 NCBI chrNW_004955455:11,387,140...11,401,178 JBrowse link
G Sirt1 sirtuin 1 ISO (PMID:23960241) BHF-UCL PMID:23960241 NCBI chrNW_004955425:20,280,725...20,307,663 JBrowse link
G Skil SKI like proto-oncogene ISO (MGI:MGI:3797158|PMID:18212064) MGI PMID:18212064 MGI:MGI:3797158 NCBI chrNW_004955420:530,531...554,308 JBrowse link
G Smad2 SMAD family member 2 ISO PMID:22073128
(MGI:MGI:3797158|PMID:18212064)
(PMID:8980228)
(MGI:MGI:2153598|PMID:11557747), (MGI:MGI:3032478|PMID:14749725)
(PMID:18548003), (PMID:8752209), (PMID:9389648), (PMID:9732876)
BHF-UCL
MGI
PMID:8752209, PMID:8980228, PMID:9389648, PMID:9732876, PMID:11557747, PMID:14749725, PMID:18212064, PMID:18548003, PMID:22073128 MGI:MGI:2153598, MGI:MGI:3032478, MGI:MGI:3797158, RGD:8554355 NCBI chrNW_004955402:33,131,760...33,217,144 JBrowse link
G Smad3 SMAD family member 3 ISO (MGI:MGI:3505646|PMID:15239668), (MGI:MGI:3690196|PMID:16619037), (MGI:MGI:5300220|PMID:21937600)
PMID:22073128
TGFbeta-1 dependent, in pancreatic stellate cells
(PMID:18548003), (PMID:21947082), (PMID:9732876)
MGI
BHF-UCL
RGD
PMID:9732876, PMID:15239668, PMID:16371439, PMID:16619037, PMID:16891311, PMID:18548003, PMID:21937600, PMID:21947082, PMID:22073128 MGI:MGI:3505646, MGI:MGI:3690196, MGI:MGI:5300220, RGD:1625706, RGD:2300404, RGD:8554355 NCBI chrNW_004955450:8,747,651...8,842,003 JBrowse link
G Smad4 SMAD family member 4 ISO (MGI:MGI:3769957|PMID:16330325)
(MGI:MGI:3797158|PMID:18212064)
(PMID:25514493)
(PMID:9389648), (PMID:9732876)
BHF-UCL
MGI
UniProt
PMID:9389648, PMID:9732876, PMID:16330325, PMID:18212064, PMID:25514493 MGI:MGI:3769957, MGI:MGI:3797158 NCBI chrNW_004955402:35,956,080...36,001,746 JBrowse link
G Smad5 SMAD family member 5 ISO (MGI:MGI:1935017|PMID:11376112) MGI PMID:11376112 MGI:MGI:1935017 NCBI chrNW_004955408:31,183,727...31,228,355 JBrowse link
G Smad7 SMAD family member 7 ISO (MGI:MGI:2153598|PMID:11557747) MGI PMID:11557747 MGI:MGI:2153598 NCBI chrNW_004955402:34,028,184...34,058,949 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO (PMID:24036928) UniProtKB PMID:24036928 NCBI chrNW_004955445:19,213,210...19,227,670 JBrowse link
G Tab1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO (MGI:MGI:2447107|PMID:12464436) MGI PMID:12464436 MGI:MGI:2447107 NCBI chrNW_004955413:25,290,733...25,315,267 JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO (MGI:MGI:2386340|PMID:12208849), (MGI:MGI:5543310|PMID:23868260)
(PMID:11157754), (PMID:9389648)
MGI
BHF-UCL
PMID:9389648, PMID:11157754, PMID:12208849, PMID:23868260 MGI:MGI:2386340, MGI:MGI:5543310 NCBI chrNW_004955555:274,405...288,441 JBrowse link
G Tgfb2 transforming growth factor beta 2 ISO (PMID:11157754), (PMID:18358889) BHF-UCL PMID:11157754, PMID:18358889 NCBI chrNW_004955406:174,949...249,248 JBrowse link
G Tgfb3 transforming growth factor beta 3 ISO (PMID:11157754), (PMID:18718461) BHF-UCL PMID:11157754, PMID:18718461 NCBI chrNW_004955438:33,129...55,180 JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 ISO (MGI:MGI:2679137|PMID:14580334), (MGI:MGI:3575204|PMID:15820682)
(MGI:MGI:3703113|PMID:17078885)
(MGI:MGI:1933434|PMID:11285230)
(MGI:MGI:3820811|PMID:18718461)
(MGI:MGI:5298182|PMID:21832243)
(PMID:11157754), (PMID:9389648)
(PMID:1333888)
MGI
BHF-UCL
RGD
PMID:1333888, PMID:8272871, PMID:9389648, PMID:11157754, PMID:11285230, PMID:14580334, PMID:15820682, PMID:17078885, PMID:17505012, PMID:18684975, PMID:18718461, PMID:21832243 MGI:MGI:1933434, MGI:MGI:2679137, MGI:MGI:3575204, MGI:MGI:3703113, MGI:MGI:3820811, MGI:MGI:5298182, RGD:2302021, RGD:2302517, RGD:737663 NCBI chrNW_004955419:26,490,899...26,546,349 JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 ISO (PMID:11157754), (PMID:1333888)
(MGI:MGI:4949016|PMID:21420963)
(PMID:18453574)
BHF-UCL
MGI
RGD
PMID:1333888, PMID:11157754, PMID:18453574, PMID:18684975, PMID:21420963 MGI:MGI:4949016, RGD:2302517 NCBI chrNW_004955430:21,919,338...21,999,688 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO (PMID:12958365)
(MGI:MGI:2663364|PMID:12773577)
(PMID:11157754)
(MGI:MGI:3699491|PMID:17295310), (MGI:MGI:3807767|PMID:11546783)
BHF-UCL PMID:11157754, PMID:11546783, PMID:12773577, PMID:12958365, PMID:17295310 MGI:MGI:2663364, MGI:MGI:3699491, MGI:MGI:3807767 NCBI chrNW_004955423:2,573,851...2,765,353 JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:3797158|PMID:18212064) MGI PMID:18212064 MGI:MGI:3797158 NCBI chrNW_004955467:9,241,391...9,256,716 JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 ISO (PMID:17164348) BHF-UCL PMID:17164348 NCBI chrNW_004955402:2,652,020...2,685,350 JBrowse link
G Usp15 ubiquitin specific peptidase 15 ISO (PMID:21947082)
(PMID:22344298)
UniProtKB PMID:21947082, PMID:22344298 NCBI chrNW_004955458:9,440,645...9,533,653 JBrowse link
G Usp9x ubiquitin specific peptidase 9 X-linked ISO (PMID:19135894) UniProtKB PMID:19135894 NCBI chrNW_004955565:1,479,040...1,602,070 JBrowse link
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 ISO (MGI:MGI:2676508|PMID:12595574) MGI PMID:12595574 MGI:MGI:2676508 NCBI chrNW_004955451:10,976,748...10,982,482 JBrowse link
G Zfyve9 zinc finger FYVE-type containing 9 ISO (PMID:9865696) UniProtKB PMID:9865696 NCBI chrNW_004955464:6,805,960...6,935,337 JBrowse link
G Zmiz1 zinc finger MIZ-type containing 1 ISO (PMID:16777850) UniProt PMID:16777850 NCBI chrNW_004955437:13,338,077...13,534,283 JBrowse link
G Zmiz2 zinc finger MIZ-type containing 2 NOT ISO (PMID:16777850) UniProt PMID:16777850 NCBI chrNW_004955456:7,393,675...7,407,710 JBrowse link
G Zyx zyxin ISO (MGI:MGI:5582864|PMID:24036928)
(PMID:24036928)
UniProtKB PMID:24036928 MGI:MGI:5582864 NCBI chrNW_004955494:268,844...277,381 JBrowse link
transforming growth factor beta receptor signaling pathway involved in heart development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor beta 1 ISO (MGI:MGI:67103|PMID:8009224) BHF-UCL PMID:8009224 MGI:MGI:67103 NCBI chrNW_004955555:274,405...288,441 JBrowse link
transforming growth factor beta receptor signaling pathway involved in primitive streak formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor ISO (MGI:MGI:2677178|PMID:14511481) MGI PMID:14511481 MGI:MGI:2677178 NCBI chrNW_004955437:20,828,448...20,835,486 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11857
    response to stimulus 6353
      response to endogenous stimulus 1681
        response to transforming growth factor beta 246
          cellular response to transforming growth factor beta stimulus + 237
Path 2
Term Annotations click to browse term
  biological_process 11857
    response to stimulus 6353
      response to chemical 3715
        response to organic substance 2997
          response to growth factor 720
            response to transforming growth factor beta 246
              cellular response to transforming growth factor beta stimulus + 237
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.