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ONTOLOGY REPORT - ANNOTATIONS


Term:response to transforming growth factor beta
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Accession:GO:0071559 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
Synonyms:exact_synonym: response to TGF-beta stimulus;   response to TGFbeta stimulus;   response to transforming growth factor beta stimulus


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response to transforming growth factor beta term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALD1 caldesmon 1 NOT ISO (MGI:MGI:5582864|PMID:24036928) UniProtKB PMID:24036928 MGI:MGI:5582864 NCBI chr 7:134,779,629...134,970,729
Ensembl chr 7:134,744,252...134,970,729
JBrowse link
G CITED1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 IDA (PMID:9707553) UniProtKB PMID:9707553 NCBI chr  X:72,301,646...72,307,157
Ensembl chr  X:72,301,638...72,307,187
JBrowse link
G DSPP dentin sialophosphoprotein ISO RGD PMID:22012415 RGD:12914763 NCBI chr 4:87,608,529...87,616,873
Ensembl chr 4:87,608,529...87,616,873
JBrowse link
G EDN1 endothelin 1 ISO RGD PMID:11061980 RGD:8662323 NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G ENG endoglin ISO RGD PMID:22941949 RGD:7248789 NCBI chr 9:127,815,012...127,854,773
Ensembl chr 9:127,815,013...127,854,658
Ensembl chr 9:127,815,013...127,854,658
JBrowse link
G FNDC4 fibronectin type III domain containing 4 IEP (PMID:27066907) UniProtKB PMID:27066907 NCBI chr 2:27,491,883...27,495,502
Ensembl chr 2:27,491,883...27,495,200
JBrowse link
G GDF10 growth differentiation factor 10 ISO RGD PMID:10079200 RGD:2316373 NCBI chr10:47,300,197...47,313,577
Ensembl chr10:47,300,197...47,313,577
JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO RGD PMID:9233842 RGD:8662880 NCBI chr 2:102,069,638...102,179,874
Ensembl chr 2:102,064,544...102,179,874
JBrowse link
G ITGB1 integrin subunit beta 1 ISO TGF-beta2 RGD PMID:18378961 RGD:2325302 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,900,318...33,005,792
JBrowse link
G MEN1 menin 1 IEA Ensembl GO_REF:0000107 NCBI chr11:64,803,514...64,811,294
Ensembl chr11:64,803,510...64,811,294
JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming ISO RGD PMID:15980276 RGD:8693640 NCBI chr11:1,074,875...1,110,508
Ensembl chr11:1,074,875...1,110,511
JBrowse link
G MXRA5 matrix remodeling associated 5 IMP
IBA
(PMID:27599751)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:27599751 NCBI chr  X:3,308,565...3,346,652
Ensembl chr  X:3,308,565...3,346,652
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 ISS ARUK-UCL GO_REF:0000024 NCBI chr18:20,946,906...21,111,813
Ensembl chr18:20,946,906...21,111,813
JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 ISS ARUK-UCL GO_REF:0000024 NCBI chr 2:11,179,759...11,345,437
Ensembl chr 2:11,179,759...11,348,330
JBrowse link
G RUNX3 RUNX family transcription factor 3 IDA (PMID:20599712) UniProtKB PMID:20599712 NCBI chr 1:24,899,511...24,965,158
Ensembl chr 1:24,899,511...24,965,121
JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:16105028 RGD:8547842 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SMAD4 SMAD family member 4 IDA (PMID:9707553) UniProtKB PMID:9707553 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,394...51,085,045
JBrowse link
G ZFHX3 zinc finger homeobox 3 IDA (PMID:20599712) UniProtKB PMID:20599712 NCBI chr16:72,782,885...73,891,931
Ensembl chr16:72,782,885...73,891,871
JBrowse link
cellular response to transforming growth factor beta stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO RGD PMID:15629889 RGD:8693572 NCBI chr 9:130,713,881...130,887,675
Ensembl chr 9:130,713,016...130,887,675
JBrowse link
G ACTR3 actin related protein 3 ISO RGD PMID:22319661 RGD:11530045 NCBI chr 2:113,889,934...113,962,596
Ensembl chr 2:113,890,063...113,962,596
JBrowse link
G ACVRL1 activin A receptor like type 1 IDA (PMID:19494318) BHF-UCL PMID:19494318 NCBI chr12:51,906,913...51,923,361
Ensembl chr12:51,906,908...51,923,361
JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 ISO RGD PMID:2401226 RGD:10053613 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686
JBrowse link
G ANKRD1 ankyrin repeat domain 1 IDA (PMID:11139470) BHF-UCL PMID:11139470 NCBI chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 IEA Ensembl GO_REF:0000107 NCBI chr12:98,645,141...98,735,433
Ensembl chr12:98,645,141...98,735,433
Ensembl chr12:98,645,141...98,735,433
JBrowse link
G ARG1 arginase 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
JBrowse link
G CAV1 caveolin 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,525,001...116,561,184
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO RGD PMID:20429874 RGD:4889909 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO RGD PMID:11369440 RGD:11252200 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CILP cartilage intermediate layer protein IDA (PMID:29167509) BHF-UCL PMID:29167509 NCBI chr15:65,194,760...65,213,142
Ensembl chr15:65,194,760...65,211,473
JBrowse link
G CLDN1 claudin 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446
JBrowse link
G CLEC3B C-type lectin domain family 3 member B IEP (PMID:7589422) UniProtKB PMID:7589422 NCBI chr 3:45,026,207...45,036,071
Ensembl chr 3:45,001,548...45,036,071
JBrowse link
G COL1A1 collagen type I alpha 1 chain IEA Ensembl GO_REF:0000107 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,183,289...50,201,632
Ensembl chr17:50,183,289...50,201,632
JBrowse link
G COL4A2 collagen type IV alpha 2 chain IEA Ensembl GO_REF:0000107 NCBI chr13:110,307,284...110,513,209
Ensembl chr13:110,305,812...110,513,209
JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO RGD PMID:21308733 RGD:10059386 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CRK CRK proto-oncogene, adaptor protein IEA Ensembl GO_REF:0000107 NCBI chr17:1,420,693...1,456,232
Ensembl chr17:1,420,689...1,463,162
JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein IMP (PMID:23959425) ARUK-UCL PMID:23959425 NCBI chr22:20,917,407...20,953,747
Ensembl chr22:20,917,407...20,953,747
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:39,263,494...39,281,735
Ensembl chr 3:39,263,494...39,281,735
Ensembl chr 3:39,263,494...39,281,735
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO FSH-stimulated granulosa cells RGD PMID:18511507 RGD:4781450 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
JBrowse link
G DAB2 DAB adaptor protein 2 ISO (MGI:MGI:5442512|PMID:15894542), (MGI:MGI:5442513|PMID:15734730) UniProtKB
RGD
PMID:15734730, PMID:15894542, PMID:21762377 MGI:MGI:5442512, MGI:MGI:5442513, RGD:7243156 NCBI chr 5:39,460,870...39,462,304
Ensembl chr 5:39,371,675...39,462,300
JBrowse link
G DBN1 drebrin 1 ISO RGD PMID:22319661 RGD:11530045 NCBI chr 5:177,456,610...177,480,368
Ensembl chr 5:177,456,608...177,474,401
JBrowse link
G DLX1 distal-less homeobox 1 IMP (PMID:14671321) UniProtKB PMID:14671321 NCBI chr 2:172,085,507...172,089,674
Ensembl chr 2:172,084,740...172,089,677
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:24211420 RGD:9588224 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,345...10,231,286
JBrowse link
G EDN1 endothelin 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G ELN elastin ISO RGD PMID:9224206 RGD:9585659 NCBI chr 7:74,027,772...74,069,907
Ensembl chr 7:74,027,789...74,069,907
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO RGD PMID:24157151 RGD:13204713 NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155
JBrowse link
G EPB41L5 erythrocyte membrane protein band 4.1 like 5 IEA Ensembl GO_REF:0000107 NCBI chr 2:120,013,032...120,179,119
Ensembl chr 2:120,013,077...120,179,119
JBrowse link
G FBN1 fibrillin 1 IEA Ensembl GO_REF:0000107 NCBI chr15:48,408,313...48,645,709
Ensembl chr15:48,408,306...48,645,849
Ensembl chr15:48,408,306...48,645,849
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,334...121,598,458
Ensembl chr10:121,478,334...121,598,458
JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:16669970 RGD:1626090 NCBI chr 2:215,360,862...215,436,167
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
JBrowse link
G HDAC2 histone deacetylase 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308
JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO FSH-stimulated granulosa cells RGD PMID:18511507 RGD:4781450 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
JBrowse link
G HYAL2 hyaluronidase 2 IDA (PMID:19366691) BHF-UCL PMID:19366691 NCBI chr 3:50,317,802...50,322,768
Ensembl chr 3:50,317,790...50,322,782
JBrowse link
G ID1 inhibitor of DNA binding 1, HLH protein ISO RGD PMID:16628634 RGD:9686088 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD PMID:12837295 RGD:11568682 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G L1CAM L1 cell adhesion molecule ISO RGD PMID:16686695 RGD:6483452 NCBI chr  X:153,861,514...153,886,173
Ensembl chr  X:153,861,514...153,886,173
JBrowse link
G LIMS1 LIM zinc finger domain containing 1 IEP (PMID:21390327) UniProtKB PMID:21390327 NCBI chr 2:108,533,671...108,687,246
Ensembl chr 2:108,534,355...108,687,246
JBrowse link
G MAPK7 mitogen-activated protein kinase 7 IDA (PMID:18588859) UniProtKB PMID:18588859 NCBI chr17:19,377,721...19,383,544
Ensembl chr17:19,377,721...19,383,544
JBrowse link
G MEF2C myocyte enhancer factor 2C IDA (PMID:9770491) UniProtKB PMID:9770491 NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257
JBrowse link
G MIR125A microRNA 125a ISO RGD PMID:29700287 RGD:26884455 NCBI chr19:51,693,254...51,693,339
Ensembl chr19:51,693,254...51,693,339
JBrowse link
G MIR155 microRNA 155 ISO (MGI:MGI:5556350|PMID:24391219) MGI PMID:24391219 MGI:MGI:5556350 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
JBrowse link
G MIR192 microRNA 192 ISO (MGI:MGI:4941448|PMID:20393144) MGI PMID:20393144 MGI:MGI:4941448 NCBI chr11:64,891,137...64,891,246
Ensembl chr11:64,891,137...64,891,246
JBrowse link
G MIR21 microRNA 21 ISO (MGI:MGI:5556350|PMID:24391219) MGI PMID:24391219 MGI:MGI:5556350 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MIR223 microRNA 223 ISO RGD PMID:29689569 RGD:25823140 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979
JBrowse link
G MUC4 mucin 4, cell surface associated ISO RGD PMID:9857062 RGD:2324952 NCBI chr 3:195,746,771...195,811,929
Ensembl chr 3:195,746,765...195,811,973
JBrowse link
G NOS3 nitric oxide synthase 3 ISO RGD PMID:21792926 RGD:8662393 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NOX4 NADPH oxidase 4 IEA Ensembl GO_REF:0000107 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 IDA (PMID:12902338) CAFA PMID:12902338 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
JBrowse link
G OVOL2 ovo like zinc finger 2 ISS ARUK-UCL GO_REF:0000024 NCBI chr20:18,024,152...18,059,188
Ensembl chr20:17,956,979...18,059,188
JBrowse link
G PAK2 p21 (RAC1) activated kinase 2 ISO RGD PMID:15629889 RGD:8693572 NCBI chr 3:196,739,857...196,832,647
Ensembl chr 3:196,739,857...196,832,647
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:22073128 RGD:8554355 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,691...226,408,093
JBrowse link
G PDCD5 programmed cell death 5 IDA (PMID:24012345) UniProtKB PMID:24012345 NCBI chr19:32,581,190...32,587,453
Ensembl chr19:32,581,190...32,587,453
JBrowse link
G PDE2A phosphodiesterase 2A IEP (PMID:17704206) UniProtKB PMID:17704206 NCBI chr11:72,576,141...72,674,422
Ensembl chr11:72,576,141...72,674,591
JBrowse link
G PDE3A phosphodiesterase 3A IEP (PMID:17704206) UniProtKB PMID:17704206 NCBI chr12:20,368,537...20,688,583
Ensembl chr12:20,368,537...20,688,583
Ensembl chr12:20,368,537...20,688,583
JBrowse link
G PDGFA platelet derived growth factor subunit A ISO RGD PMID:16039137 RGD:1581755 NCBI chr 7:497,245...520,668
Ensembl chr 7:497,258...520,296
JBrowse link
G PDGFD platelet derived growth factor D IEA Ensembl GO_REF:0000107 NCBI chr11:103,907,189...104,164,147
Ensembl chr11:103,907,189...104,164,379
JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 ISO RGD PMID:15862831 RGD:9999173 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,410...43,773,278
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:18466611 RGD:2311658 NCBI chr17:64,319,415...64,413,844
Ensembl chr17:64,319,415...64,413,776
JBrowse link
G PENK proenkephalin IEA Ensembl GO_REF:0000107 NCBI chr 8:56,440,957...56,446,641
Ensembl chr 8:56,436,674...56,446,671
JBrowse link
G POSTN periostin IEA Ensembl GO_REF:0000107 NCBI chr13:37,562,585...37,598,839
Ensembl chr13:37,562,583...37,598,844
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha IEA Ensembl GO_REF:0000107 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A IEA Ensembl GO_REF:0000107 NCBI chr14:60,245,750...60,299,087
Ensembl chr14:60,245,752...60,299,087
JBrowse link
G PTK2 protein tyrosine kinase 2 ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216
JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 ISO RGD PMID:23845590 RGD:9835377 NCBI chr12:47,734,363...47,758,880
Ensembl chr12:47,734,363...47,771,040
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chr18:20,946,906...21,111,813
Ensembl chr18:20,946,906...21,111,813
JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chr 2:11,179,759...11,345,437
Ensembl chr 2:11,179,759...11,348,330
JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO (MGI:MGI:5532214|PMID:23861879) MGI PMID:23861879 MGI:MGI:5532214 NCBI chr21:34,787,801...35,049,334
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G SCX scleraxis bHLH transcription factor IEA Ensembl GO_REF:0000107 NCBI chr 8:144,265,060...144,268,483
Ensembl chr 8:144,266,453...144,268,481
JBrowse link
G SERPINE1 serpin family E member 1 ISO (MGI:MGI:5289760|PMID:21829547) MGI
RGD
PMID:19247458, PMID:21829547 MGI:MGI:5289760, RGD:8547745 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SFRP1 secreted frizzled related protein 1 IEP (PMID:16149051) UniProtKB PMID:16149051 NCBI chr 8:41,261,962...41,309,473
Ensembl chr 8:41,261,962...41,309,473
JBrowse link
G SMAD3 SMAD family member 3 IDA (PMID:12902338) CAFA PMID:12902338 NCBI chr15:67,065,602...67,195,195
Ensembl chr15:67,063,763...67,195,169
JBrowse link
G SMAD7 SMAD family member 7 IMP (PMID:18593713) BHF-UCL PMID:18593713 NCBI chr18:48,919,853...48,950,711
Ensembl chr18:48,919,853...48,952,052
JBrowse link
G SNRNP70 small nuclear ribonucleoprotein U1 subunit 70 ISO RGD PMID:10022522 RGD:10448942 NCBI chr19:49,085,451...49,108,606
Ensembl chr19:49,085,419...49,108,605
JBrowse link
G SOX5 SRY-box transcription factor 5 IDA (PMID:21401405) UniProtKB PMID:21401405 NCBI chr12:23,529,499...24,562,701
Ensembl chr12:23,529,504...24,562,544
JBrowse link
G SOX6 SRY-box transcription factor 6 IDA (PMID:21401405) UniProtKB PMID:21401405 NCBI chr11:15,966,449...16,738,477
Ensembl chr11:15,966,449...16,739,591
JBrowse link
G SOX9 SRY-box transcription factor 9 IDA (PMID:21401405) UniProtKB PMID:21401405 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chr20:37,344,690...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G STAR steroidogenic acute regulatory protein IEA Ensembl GO_REF:0000107 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
JBrowse link
G STK16 serine/threonine kinase 16 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:219,245,469...219,250,337
Ensembl chr 2:219,245,455...219,250,337
JBrowse link
G TGFB1 transforming growth factor beta 1 IGI
IDA
(PMID:22269326)
(PMID:19736306), (PMID:22269326)
BHF-UCL PMID:19736306, PMID:22269326 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 IDA (PMID:19494318) BHF-UCL PMID:19494318 NCBI chr 9:99,104,038...99,154,192
Ensembl chr 9:99,104,038...99,154,192
JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked ISO (MGI:MGI:5532214|PMID:23861879) MGI PMID:23861879 MGI:MGI:5532214 NCBI chr  X:41,085,420...41,236,579
Ensembl chr  X:41,085,445...41,236,579
JBrowse link
G WNT10A Wnt family member 10A IEP (PMID:15040835) UniProtKB PMID:15040835 NCBI chr 2:218,874,116...218,893,931
Ensembl chr 2:218,880,852...218,899,581
JBrowse link
G WNT2 Wnt family member 2 IEP (PMID:15040835) UniProtKB PMID:15040835 NCBI chr 7:117,275,451...117,323,058
Ensembl chr 7:117,275,451...117,323,152
JBrowse link
G WNT4 Wnt family member 4 IEP (PMID:15040835) UniProtKB PMID:15040835 NCBI chr 1:22,117,308...22,143,981
Ensembl chr 1:22,117,313...22,143,969
JBrowse link
G WNT5A Wnt family member 5A IEP (PMID:15040835) UniProtKB PMID:15040835 NCBI chr 3:55,465,715...55,505,261
Ensembl chr 3:55,465,715...55,490,539
JBrowse link
G WNT7A Wnt family member 7A IEP (PMID:15040835) UniProtKB PMID:15040835 NCBI chr 3:13,816,258...13,880,071
Ensembl chr 3:13,816,258...13,880,071
JBrowse link
G WWOX WW domain containing oxidoreductase IDA (PMID:19366691) BHF-UCL PMID:19366691 NCBI chr16:78,099,654...79,212,667
Ensembl chr16:78,099,430...79,212,667
JBrowse link
G XCL1 X-C motif chemokine ligand 1 ISS BHF-UCL GO_REF:0000024 NCBI chr 1:168,574,128...168,582,069
Ensembl chr 1:168,576,605...168,582,069
JBrowse link
G YES1 YES proto-oncogene 1, Src family tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr18:721,588...812,846
Ensembl chr18:721,588...812,546
JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 ISO RGD PMID:16824956 RGD:2325877 NCBI chr10:31,318,417...31,529,804
Ensembl chr10:31,318,495...31,529,814
JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 IDA (PMID:20166898) UniProtKB PMID:20166898 NCBI chr14:68,787,655...68,796,243
Ensembl chr14:68,787,660...68,796,253
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 IDA (PMID:20166898) UniProtKB PMID:20166898 NCBI chr 2:43,222,402...43,226,606
Ensembl chr 2:43,222,402...43,226,606
JBrowse link
negative regulation of cellular response to transforming growth factor beta stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFLAR CASP8 and FADD like apoptosis regulator IEA Ensembl GO_REF:0000107 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687
JBrowse link
G DLX1 distal-less homeobox 1 IMP (PMID:14671321) UniProtKB PMID:14671321 NCBI chr 2:172,085,507...172,089,674
Ensembl chr 2:172,084,740...172,089,677
JBrowse link
G IL4 interleukin 4 IDA (PMID:11967989) UniProt PMID:11967989 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
negative regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 IMP (PMID:21170088) UniProtKB PMID:21170088 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732
JBrowse link
G ADAMTSL2 ADAMTS like 2 IMP (PMID:18677313) BHF-UCL PMID:18677313 NCBI chr 9:133,532,164...133,575,519
Ensembl chr 9:133,532,164...133,575,519
JBrowse link
G ASPN asporin IDA (PMID:17827158) UniProtKB PMID:17827158 NCBI chr 9:92,456,205...92,482,506
Ensembl chr 9:92,456,205...92,482,506
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor IDA
TAS
IMP
(PMID:14660579)
(PMID:19328798)
BHF-UCL
Reactome
PMID:14660579, PMID:19328798 Reactome:R-HSA-173483 NCBI chr10:28,677,521...28,682,932
Ensembl chr10:28,677,510...28,682,932
JBrowse link
G BCL9L BCL9 like IMP
IBA
(PMID:19328798)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:19328798, PMID:21873635 NCBI chr11:118,896,136...118,926,071
Ensembl chr11:118,893,875...118,925,608
JBrowse link
G CAV1 caveolin 1 IDA (PMID:25893292) UniProtKB PMID:25893292 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,525,001...116,561,184
JBrowse link
G CAV2 caveolin 2 IEA Ensembl GO_REF:0000107 NCBI chr 7:116,499,738...116,508,541
Ensembl chr 7:116,287,380...116,508,541
JBrowse link
G CD109 CD109 molecule IDA (PMID:16754747) UniProtKB PMID:16754747 NCBI chr 6:73,696,203...73,828,313
Ensembl chr 6:73,695,785...73,828,316
JBrowse link
G CHST11 carbohydrate sulfotransferase 11 IEA Ensembl GO_REF:0000107 NCBI chr12:104,456,948...104,762,014
Ensembl chr12:104,455,295...104,762,014
JBrowse link
G CIDEA cell death inducing DFFA like effector a ISS (PMID:17080483) BHF-UCL PMID:17080483 NCBI chr18:12,254,361...12,277,595
Ensembl chr18:12,254,361...12,277,595
JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 ISS BHF-UCL GO_REF:0000024 NCBI chr19:12,969,576...12,974,760
Ensembl chr19:12,965,159...12,974,762
JBrowse link
G DNM2 dynamin 2 IEA Ensembl GO_REF:0000107 NCBI chr19:10,718,079...10,831,903
Ensembl chr19:10,718,079...10,833,488
JBrowse link
G EID2 EP300 interacting inhibitor of differentiation 2 IDA (PMID:14612439) HGNC PMID:14612439 NCBI chr19:39,538,707...39,540,161
Ensembl chr19:39,538,707...39,540,161
JBrowse link
G EMILIN1 elastin microfibril interfacer 1 ISS BHF-UCL GO_REF:0000024 NCBI chr 2:27,078,615...27,086,403
Ensembl chr 2:27,078,615...27,086,403
JBrowse link
G ENG endoglin TAS (PMID:11382917) BHF-UCL PMID:11382917 NCBI chr 9:127,815,012...127,854,773
Ensembl chr 9:127,815,013...127,854,658
Ensembl chr 9:127,815,013...127,854,658
JBrowse link
G FAM89B family with sequence similarity 89 member B ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr11:65,572,538...65,574,190
Ensembl chr11:65,572,349...65,574,198
JBrowse link
G GLG1 golgi glycoprotein 1 IEA Ensembl GO_REF:0000107 NCBI chr16:74,447,440...74,607,114
Ensembl chr16:74,447,427...74,607,144
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A IMP (PMID:24613385) UniProtKB PMID:24613385 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B IMP (PMID:24613385) UniProtKB PMID:24613385 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 IEA Ensembl GO_REF:0000107 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G HTRA1 HtrA serine peptidase 1 IEA Ensembl GO_REF:0000107 NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907
JBrowse link
G HTRA3 HtrA serine peptidase 3 ISS UniProtKB GO_REF:0000024 NCBI chr 4:8,269,712...8,307,098
Ensembl chr 4:8,269,754...8,307,098
JBrowse link
G HTRA4 HtrA serine peptidase 4 ISS UniProtKB GO_REF:0000024 NCBI chr 8:38,974,149...38,988,663
Ensembl chr 8:38,974,228...38,988,663
JBrowse link
G IL17RD interleukin 17 receptor D ISS UniProt GO_REF:0000024 NCBI chr 3:57,089,982...57,170,317
Ensembl chr 3:57,089,982...57,170,306
JBrowse link
G LDLRAD4 low density lipoprotein receptor class A domain containing 4 IMP
IEA
IBA
IDA
(PMID:24627487)
(PMID:21873635)
UniProtKB
InterPro
GO_Central
PMID:21873635, PMID:24627487 GO_REF:0000002 NCBI chr18:13,217,606...13,652,754
Ensembl chr18:13,217,498...13,652,755
JBrowse link
G LEMD3 LEM domain containing 3 IDA (PMID:15647271) UniProtKB PMID:15647271 NCBI chr12:65,169,583...65,248,355
Ensembl chr12:65,169,583...65,248,355
JBrowse link
G MECOM MDS1 and EVI1 complex locus NOT IDA (PMID:15897867) UniProt PMID:15897867 NCBI chr 3:169,083,506...169,663,781
Ensembl chr 3:169,083,499...169,663,775
JBrowse link
G MTMR4 myotubularin related protein 4 TAS Reactome Reactome:R-HSA-2173788 NCBI chr17:58,489,537...58,518,109
Ensembl chr17:58,489,529...58,517,905
JBrowse link
G NEPNP nephrocan, pseudogene ISO (MGI:MGI:3698676|PMID:16990280) MGI PMID:16990280 MGI:MGI:3698676 NCBI chr 6:117,602,928...117,645,087
Ensembl chr 6:117,633,706...117,645,087
JBrowse link
G NKX2-1 NK2 homeobox 1 IDA (PMID:19293183) UniProtKB PMID:19293183 NCBI chr14:36,516,397...36,520,232
Ensembl chr14:36,516,392...36,521,149
JBrowse link
G ONECUT1 one cut homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr15:52,755,053...52,790,336
Ensembl chr15:52,755,053...52,791,078
JBrowse link
G ONECUT2 one cut homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr18:57,435,374...57,491,298
Ensembl chr18:57,435,374...57,491,298
JBrowse link
G PBLD phenazine biosynthesis like protein domain containing IMP (PMID:23687415) UniProtKB PMID:23687415 NCBI chr10:68,282,660...68,332,958
Ensembl chr10:68,282,660...68,333,049
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 IDA (PMID:17327236) UniProtKB PMID:17327236 NCBI chr16:2,538,014...2,603,190
Ensembl chr16:2,537,979...2,603,188
JBrowse link
G PEG10 paternally expressed 10 IDA (PMID:15611116) HGNC PMID:15611116 NCBI chr 7:94,656,325...94,669,695
Ensembl chr 7:94,656,325...94,669,695
JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 IDA (PMID:19122240) BHF-UCL PMID:19122240 NCBI chr19:9,835,318...9,849,689
Ensembl chr19:9,835,257...9,849,682
Ensembl chr19:9,835,257...9,849,682
JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 TAS
IEA
IBA
IDA
IMP
(PMID:21873635)
(PMID:24627487)
(PMID:20129061)
Reactome
InterPro
GO_Central
UniProtKB
PMID:20129061, PMID:21873635, PMID:24627487 GO_REF:0000002, Reactome:R-HSA-2173788 NCBI chr20:57,648,396...57,711,472
Ensembl chr20:57,648,392...57,711,536
JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A IDA (PMID:16751101) UniProtKB PMID:16751101 NCBI chr14:60,245,750...60,299,087
Ensembl chr14:60,245,752...60,299,087
JBrowse link
G PRDM16 PR/SET domain 16 NOT IMP
IDA
(PMID:19049980)
(PMID:14656887)
UniProtKB PMID:14656887, PMID:19049980 NCBI chr 1:3,069,203...3,438,621
Ensembl chr 1:3,069,168...3,438,621
JBrowse link
G RASL11B RAS like family 11 member B IEA Ensembl GO_REF:0000107 NCBI chr 4:52,862,317...52,866,835
Ensembl chr 4:52,862,317...52,866,835
JBrowse link
G RPS27A ribosomal protein S27a TAS Reactome Reactome:R-HSA-2173788 NCBI chr 2:55,231,903...55,235,853
Ensembl chr 2:55,231,903...55,235,853
JBrowse link
G SIRT1 sirtuin 1 ISS UniProtKB GO_REF:0000024 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SKI SKI proto-oncogene IGI
IBA
IMP
IDA
(PMID:15312649)
(PMID:21873635)
(PMID:17054724), (PMID:19049980)
(PMID:17469184)
MGI
GO_Central
UniProtKB
PMID:15312649, PMID:17054724, PMID:17469184, PMID:19049980, PMID:21873635 NCBI chr 1:2,228,319...2,310,213
Ensembl chr 1:2,228,319...2,310,213
JBrowse link
G SKIL SKI like proto-oncogene IEA
IBA
IDA
(PMID:21873635)
(PMID:17469184), (PMID:19383336)
InterPro
GO_Central
UniProtKB
PMID:17469184, PMID:19383336, PMID:21873635 GO_REF:0000002 NCBI chr 3:170,357,678...170,396,849
Ensembl chr 3:170,357,678...170,396,835
JBrowse link
G SKOR2 SKI family transcriptional corepressor 2 NOT IEA
ISO
IDA
(MGI:MGI:5300220|PMID:21937600)
(PMID:16200078)
InterPro
MGI
UniProtKB
PMID:16200078, PMID:21937600 GO_REF:0000002, MGI:MGI:5300220 NCBI chr18:47,206,169...47,251,660
Ensembl chr18:47,206,322...47,251,603
Ensembl chr18:47,206,322...47,251,603
JBrowse link
G SLC2A10 solute carrier family 2 member 10 IMP (PMID:16550171), (PMID:26376865) ARUK-UCL PMID:16550171, PMID:26376865 NCBI chr20:46,708,358...46,736,347
Ensembl chr20:46,709,649...46,736,347
JBrowse link
G SMAD2 SMAD family member 2 TAS Reactome Reactome:R-HSA-2173788 NCBI chr18:47,808,957...47,931,188
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SMAD3 SMAD family member 3 TAS Reactome Reactome:R-HSA-2173788 NCBI chr15:67,065,602...67,195,195
Ensembl chr15:67,063,763...67,195,169
JBrowse link
G SMAD6 SMAD family member 6 IMP
IDA
(PMID:19047146)
(PMID:9256479)
BHF-UCL PMID:9256479, PMID:19047146 NCBI chr15:66,702,110...66,782,849
Ensembl chr15:66,702,236...66,782,849
JBrowse link
G SMAD7 SMAD family member 7 TAS
IDA
(PMID:12151385), (PMID:17438144), (PMID:18762808), (PMID:9256479) Reactome
BHF-UCL
PMID:9256479, PMID:12151385, PMID:17438144, PMID:18762808 Reactome:R-HSA-173483, Reactome:R-HSA-173512, Reactome:R-HSA-2173788 NCBI chr18:48,919,853...48,950,711
Ensembl chr18:48,919,853...48,952,052
JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 IDA (PMID:11278251), (PMID:12151385) BHF-UCL PMID:11278251, PMID:12151385 NCBI chr 7:99,027,435...99,144,118
Ensembl chr 7:99,027,438...99,144,100
JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 IDA
TAS
(PMID:19255252) CACAO
Reactome
PMID:19255252 Reactome:R-HSA-2173788 NCBI chr17:64,542,282...64,662,307
Ensembl chr17:64,542,282...64,662,307
JBrowse link
G SNX1 sorting nexin 1 ISO (MGI:MGI:3505646|PMID:15239668) MGI PMID:15239668 MGI:MGI:3505646 NCBI chr15:64,094,066...64,144,231
Ensembl chr15:64,094,123...64,146,090
JBrowse link
G SNX25 sorting nexin 25 IEA
IMP
(PMID:21266196) InterPro
UniProtKB
PMID:21266196 GO_REF:0000002 NCBI chr 4:185,204,237...185,368,020
Ensembl chr 4:185,204,237...185,370,185
JBrowse link
G SNX6 sorting nexin 6 IDA (PMID:11279102) HGNC PMID:11279102 NCBI chr14:34,561,093...34,630,148
Ensembl chr14:34,561,093...34,630,160
JBrowse link
G SPINT3 serine peptidase inhibitor, Kunitz type 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:45,512,461...45,515,622
Ensembl chr20:45,512,461...45,515,622
JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 ISS UniProt GO_REF:0000024 NCBI chr15:38,252,087...38,357,249
Ensembl chr15:38,252,836...38,357,249
JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 ISS UniProt GO_REF:0000024 NCBI chr 2:65,307,425...65,432,599
Ensembl chr 2:65,310,851...65,432,637
JBrowse link
G SPRED3 sprouty related EVH1 domain containing 3 ISS UniProt GO_REF:0000024 NCBI chr19:38,390,061...38,399,884
Ensembl chr19:38,388,421...38,399,587
JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 ISS UniProt GO_REF:0000024 NCBI chr 4:123,396,795...123,403,760
Ensembl chr 4:123,396,795...123,403,760
JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 ISS UniProt GO_REF:0000024 NCBI chr13:80,335,976...80,341,126
Ensembl chr13:80,335,976...80,341,126
JBrowse link
G STRAP serine/threonine kinase receptor associated protein TAS
IMP
(PMID:23687415) Reactome
UniProtKB
PMID:23687415 Reactome:R-HSA-2173788 NCBI chr12:15,882,382...15,903,478
Ensembl chr12:15,882,387...15,903,478
JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 TAS
IMP
(PMID:24613385) Reactome
UniProtKB
PMID:24613385 Reactome:R-HSA-2173788 NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870
JBrowse link
G TDGF1 teratocarcinoma-derived growth factor 1 ISO (MGI:MGI:3771280|PMID:17991893) MGI PMID:17991893 MGI:MGI:3771280 NCBI chr 3:46,574,535...46,582,457
Ensembl chr 3:46,574,534...46,582,457
JBrowse link
G TGFB1 transforming growth factor beta 1 TAS Reactome Reactome:R-HSA-173483, Reactome:R-HSA-173512, Reactome:R-HSA-2173788 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 IDA (PMID:18762808) BHF-UCL PMID:18762808 NCBI chr16:31,472,152...31,477,960
Ensembl chr16:31,471,585...31,477,960
JBrowse link
G TGFB3 transforming growth factor beta 3 IEA Ensembl GO_REF:0000107 NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 TAS Reactome Reactome:R-HSA-173483, Reactome:R-HSA-173512, Reactome:R-HSA-2173788 NCBI chr 9:99,104,038...99,154,192
Ensembl chr 9:99,104,038...99,154,192
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 TAS Reactome Reactome:R-HSA-173483, Reactome:R-HSA-173512, Reactome:R-HSA-2173788 NCBI chr 3:30,606,472...30,694,142
Ensembl chr 3:30,606,601...30,694,142
Ensembl chr 3:30,606,601...30,694,142
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 IEA Ensembl GO_REF:0000107 NCBI chr 1:91,680,343...91,906,002
Ensembl chr 1:91,680,343...91,906,335
JBrowse link
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 TAS Reactome Reactome:R-HSA-2173788 NCBI chr19:18,563,766...18,577,550
Ensembl chr19:18,571,730...18,577,550
JBrowse link
G UBB ubiquitin B TAS Reactome Reactome:R-HSA-2173788 NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745
JBrowse link
G UBC ubiquitin C TAS Reactome Reactome:R-HSA-2173788 NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368
JBrowse link
G VASN vasorin IDA
IBA
IMP
(PMID:15247411)
(PMID:21873635)
(PMID:21170088)
UniProtKB
GO_Central
PMID:15247411, PMID:21170088, PMID:21873635 NCBI chr16:4,371,848...4,383,538
Ensembl chr16:4,371,848...4,383,538
JBrowse link
G VEPH1 ventricular zone expressed PH domain containing 1 IDA (PMID:26039994) UniProt PMID:26039994 NCBI chr 3:157,259,742...157,503,777
Ensembl chr 3:157,259,742...157,533,619
JBrowse link
G WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 IDA
IBA
(PMID:21054789)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21054789, PMID:21873635 NCBI chr16:630,985...634,117
Ensembl chr16:629,239...634,117
JBrowse link
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 IDA
IBA
(PMID:21054789)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21054789, PMID:21873635 NCBI chr17:50,834,584...50,842,353
Ensembl chr17:50,834,650...50,842,353
JBrowse link
G WNT1 Wnt family member 1 IEA Ensembl GO_REF:0000107 NCBI chr12:48,978,322...48,982,620
Ensembl chr12:48,978,322...48,982,620
JBrowse link
G XBP1 X-box binding protein 1 IDA (PMID:26315405) BHF-UCL PMID:26315405 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A IMP (PMID:25514493) UniProt PMID:25514493 NCBI chr19:4,043,303...4,066,899
Ensembl chr19:4,043,303...4,066,899
JBrowse link
G ZNF451 zinc finger protein 451 IMP (PMID:24324267) UniProtKB PMID:24324267 NCBI chr 6:57,088,970...57,170,305
Ensembl chr 6:57,086,844...57,170,305
JBrowse link
positive regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 ISS (PMID:10433800) BHF-UCL PMID:10433800 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732
JBrowse link
G AXIN1 axin 1 ISO (MGI:MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:MGI:3628833 NCBI chr16:287,440...355,226
Ensembl chr16:287,440...352,723
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C IMP (PMID:16943770) BHF-UCL PMID:16943770 NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775
Ensembl chr11:2,883,213...2,885,775
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B IMP (PMID:16943770) BHF-UCL PMID:16943770 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CITED1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 TAS (PMID:17336183) BHF-UCL PMID:17336183 NCBI chr  X:72,301,646...72,307,157
Ensembl chr  X:72,301,638...72,307,187
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 IEA
ISS
Ensembl
UniProtKB
GO_REF:0000024, GO_REF:0000107 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648
JBrowse link
G CREBBP CREB binding protein IMP (PMID:25514493) UniProt PMID:25514493 NCBI chr16:3,725,054...3,880,727
Ensembl chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G DAB2 DAB adaptor protein 2 IDA (PMID:11387212) UniProt PMID:11387212 NCBI chr 5:39,371,677...39,424,980
Ensembl chr 5:39,371,675...39,462,300
JBrowse link
G EP300 E1A binding protein p300 IMP (PMID:25514493) UniProt PMID:25514493 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077
JBrowse link
G FERMT1 fermitin family member 1 IEA Ensembl GO_REF:0000107 NCBI chr20:6,074,845...6,123,609
Ensembl chr20:6,074,845...6,123,030
Ensembl chr20:6,074,845...6,123,030
JBrowse link
G FLCN folliculin IDA
IBA
ISS
(PMID:20573232)
(PMID:21873635)
UniProtKB
GO_Central
PMID:20573232, PMID:21873635 GO_REF:0000024 NCBI chr17:17,206,946...17,237,188
Ensembl chr17:17,212,212...17,237,188
JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme ISO RGD PMID:15194465 RGD:1582619 NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,458
JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 ISS BHF-UCL GO_REF:0000024 NCBI chr19:14,477,761...14,496,133
Ensembl chr19:14,477,760...14,496,149
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 IEA Ensembl GO_REF:0000107 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 IMP (PMID:14678985) UniProtKB PMID:14678985 NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 IDA (PMID:24613385) UniProtKB PMID:24613385 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
JBrowse link
G ING2 inhibitor of growth family member 2 IDA (PMID:18334480) UniProtKB PMID:18334480 NCBI chr 4:183,505,058...183,512,429
Ensembl chr 4:183,505,058...183,512,429
JBrowse link
G ITGA8 integrin subunit alpha 8 IEA Ensembl GO_REF:0000107 NCBI chr10:15,513,954...15,720,329
Ensembl chr10:15,513,954...15,719,922
JBrowse link
G LRG1 leucine rich alpha-2-glycoprotein 1 IEA Ensembl GO_REF:0000107 NCBI chr19:4,536,402...4,540,036
Ensembl chr19:4,536,402...4,540,036
JBrowse link
G MEN1 menin 1 IMP (PMID:11274402) UniProtKB PMID:11274402 NCBI chr11:64,803,514...64,811,294
Ensembl chr11:64,803,510...64,811,294
JBrowse link
G MYOCD myocardin IEA Ensembl GO_REF:0000107 NCBI chr17:12,665,890...12,768,949
Ensembl chr17:12,665,890...12,768,949
JBrowse link
G NPNT nephronectin IEA Ensembl GO_REF:0000107 NCBI chr 4:105,895,453...105,971,671
Ensembl chr 4:105,894,775...106,004,027
JBrowse link
G RNF111 ring finger protein 111 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:58,987,588...59,097,419
Ensembl chr15:58,865,175...59,097,419
JBrowse link
G SDCBP syndecan binding protein IMP
IBA
(PMID:25893292)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:25893292 NCBI chr 8:58,553,261...58,582,860
Ensembl chr 8:58,552,924...58,582,859
JBrowse link
G SLC2A10 solute carrier family 2 member 10 IMP (PMID:26376865) ARUK-UCL PMID:26376865 NCBI chr20:46,708,358...46,736,347
Ensembl chr20:46,709,649...46,736,347
JBrowse link
G SMAD4 SMAD family member 4 IDA (PMID:19328798) BHF-UCL PMID:19328798 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,394...51,085,045
JBrowse link
G SNW1 SNW domain containing 1 IDA (PMID:11278756) UniProtKB PMID:11278756 NCBI chr14:77,717,599...77,761,156
Ensembl chr14:77,717,599...77,761,207
JBrowse link
G STK11 serine/threonine kinase 11 IMP (PMID:18311138) BHF-UCL PMID:18311138 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431
Ensembl chr19:1,177,558...1,228,431
JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 IDA (PMID:18762808) BHF-UCL PMID:18762808 NCBI chr16:31,472,152...31,477,960
Ensembl chr16:31,471,585...31,477,960
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 IEA Ensembl GO_REF:0000107 NCBI chr 1:91,680,343...91,906,002
Ensembl chr 1:91,680,343...91,906,335
JBrowse link
G THBS1 thrombospondin 1 IDA (PMID:18555217) BHF-UCL PMID:18555217 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
JBrowse link
regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL9 BCL9 transcription coactivator NOT IMP (PMID:19328798) BHF-UCL PMID:19328798 NCBI chr 1:147,541,501...147,626,217
Ensembl chr 1:147,541,501...147,626,216
JBrowse link
G CAV3 caveolin 3 IEA Ensembl GO_REF:0000107 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808
Ensembl chr 3:8,733,802...8,841,808
JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 ISO (MGI:MGI:1335654|PMID:10208746) MGI PMID:10208746 MGI:MGI:1335654 NCBI chr19:12,969,576...12,974,760
Ensembl chr19:12,965,159...12,974,762
JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 NAS (PMID:24431302) ParkinsonsUK-UCL PMID:24431302 NCBI chr11:11,963,036...12,009,827
Ensembl chr11:11,956,207...12,009,769
JBrowse link
G EID2 EP300 interacting inhibitor of differentiation 2 IDA (PMID:14612439) HGNC PMID:14612439 NCBI chr19:39,538,707...39,540,161
Ensembl chr19:39,538,707...39,540,161
JBrowse link
G ENG endoglin IDA
IBA
(PMID:15702480)
(PMID:21873635)
HGNC
GO_Central
PMID:15702480, PMID:21873635 NCBI chr 9:127,815,012...127,854,773
Ensembl chr 9:127,815,013...127,854,658
Ensembl chr 9:127,815,013...127,854,658
JBrowse link
G FOLR1 folate receptor alpha ISS BHF-UCL GO_REF:0000024 NCBI chr11:72,189,709...72,196,323
Ensembl chr11:72,189,558...72,196,323
JBrowse link
G GDF2 growth differentiation factor 2 NOT ISO (MGI:MGI:4830635|PMID:20406889) DFLAT PMID:20406889 MGI:MGI:4830635 NCBI chr10:47,322,454...47,327,588
Ensembl chr10:47,322,454...47,327,588
JBrowse link
G IL17F interleukin 17F IDA (PMID:11591732) UniProtKB PMID:11591732 NCBI chr 6:52,236,681...52,245,689
Ensembl chr 6:52,236,681...52,244,500
Ensembl chr 6:52,236,681...52,244,500
JBrowse link
G ITGA3 integrin subunit alpha 3 IMP (PMID:24621570) UniProtKB PMID:24621570 NCBI chr17:50,056,065...50,090,481
Ensembl chr17:50,055,968...50,090,481
JBrowse link
G LOX lysyl oxidase IEA Ensembl GO_REF:0000107 NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,360
JBrowse link
G LTBP4 latent transforming growth factor beta binding protein 4 TAS (PMID:9660815) UniProtKB PMID:9660815 NCBI chr19:40,593,166...40,629,820
Ensembl chr19:40,592,883...40,629,818
JBrowse link
G NREP neuronal regeneration related protein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:111,728,802...111,976,932
Ensembl chr 5:111,662,621...111,997,464
JBrowse link
G SMAD2 SMAD family member 2 IMP (PMID:14555988) BHF-UCL PMID:14555988 NCBI chr18:47,808,957...47,931,188
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SMAD3 SMAD family member 3 IMP (PMID:8774881) BHF-UCL PMID:8774881 NCBI chr15:67,065,602...67,195,195
Ensembl chr15:67,063,763...67,195,169
JBrowse link
G SMAD4 SMAD family member 4 IMP (PMID:8774881) BHF-UCL PMID:8774881 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,394...51,085,045
JBrowse link
G SMAD7 SMAD family member 7 IC (PMID:18952608) BHF-UCL PMID:18952608 NCBI chr18:48,919,853...48,950,711
Ensembl chr18:48,919,853...48,952,052
JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 NAS (PMID:11158580) UniProtKB PMID:11158580 NCBI chr17:64,542,282...64,662,307
Ensembl chr17:64,542,282...64,662,307
JBrowse link
G SOX11 SRY-box transcription factor 11 IEP (PMID:20624318) UniProtKB PMID:20624318 NCBI chr 2:5,692,384...5,701,385
Ensembl chr 2:5,692,384...5,701,385
JBrowse link
G TGFB1 transforming growth factor beta 1 IDA (PMID:15334054) BHF-UCL PMID:15334054 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:91,680,343...91,906,002
Ensembl chr 1:91,680,343...91,906,335
JBrowse link
G TGFBR3L transforming growth factor beta receptor 3 like IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:7,914,830...7,919,097
Ensembl chr19:7,916,145...7,919,097
JBrowse link
G TRIM33 tripartite motif containing 33 IDA (PMID:19135894) UniProtKB PMID:19135894 NCBI chr 1:114,392,787...114,511,203
Ensembl chr 1:114,392,790...114,511,203
JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr10:31,318,417...31,529,804
Ensembl chr10:31,318,495...31,529,814
JBrowse link
G ZNF703 zinc finger protein 703 IDA (PMID:21337521) UniProtKB PMID:21337521 NCBI chr 8:37,695,782...37,700,019
Ensembl chr 8:37,695,782...37,700,019
JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBN1 fibrillin 1 ISS BHF-UCL GO_REF:0000024 NCBI chr15:48,408,313...48,645,709
Ensembl chr15:48,408,306...48,645,849
Ensembl chr15:48,408,306...48,645,849
JBrowse link
G FBN2 fibrillin 2 ISS BHF-UCL GO_REF:0000024 NCBI chr 5:128,257,909...128,538,245
Ensembl chr 5:128,257,909...128,659,185
JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 TAS
IDA
(PMID:18677313)
(PMID:2022183), (PMID:8617200)
BHF-UCL
UniProt
PMID:2022183, PMID:8617200, PMID:18677313 NCBI chr 2:32,902,129...33,399,509
Ensembl chr 2:32,946,953...33,399,509
JBrowse link
G NRROS negative regulator of reactive oxygen species ISS UniProt GO_REF:0000024 NCBI chr 3:196,639,694...196,662,004
Ensembl chr 3:196,639,694...196,662,004
JBrowse link
transforming growth factor beta receptor complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1C activin A receptor type 1C ISO TbetaR-II, ActR-II (Chlorocebus aethiops), ligand-dependent RGD PMID:8940033 RGD:631880 NCBI chr 2:157,526,767...157,628,864
Ensembl chr 2:157,526,767...157,628,864
JBrowse link
G EID2 EP300 interacting inhibitor of differentiation 2 IDA (PMID:14612439) HGNC PMID:14612439 NCBI chr19:39,538,707...39,540,161
Ensembl chr19:39,538,707...39,540,161
JBrowse link
G FMOD fibromodulin TAS (PMID:8093006) PINC PMID:8093006 NCBI chr 1:203,340,628...203,351,122
Ensembl chr 1:203,340,628...203,351,758
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 IEA Ensembl GO_REF:0000107 NCBI chr 1:91,680,343...91,906,002
Ensembl chr 1:91,680,343...91,906,335
JBrowse link
transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 IDA
IBA
(PMID:8242742)
(PMID:21873635)
UniProtKB
GO_Central
PMID:8242742, PMID:21873635 NCBI chr 2:157,736,446...157,876,330
Ensembl chr 2:157,736,444...157,876,330
Ensembl chr 2:157,736,444...157,876,330
JBrowse link
G ACVRL1 activin A receptor like type 1 IDA
IBA
(PMID:15702480)
(PMID:21873635)
HGNC
GO_Central
PMID:15702480, PMID:21873635 NCBI chr12:51,906,913...51,923,361
Ensembl chr12:51,906,908...51,923,361
JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 IMP
IBA
ISS
(PMID:11955914)
(PMID:21873635)
(PMID:8647900)
BHF-UCL
GO_Central
PMID:8647900, PMID:11955914, PMID:21873635 NCBI chr 8:38,996,767...39,105,261
Ensembl chr 8:38,996,869...39,105,261
JBrowse link
G AMHR2 anti-Mullerian hormone receptor type 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:53,423,855...53,431,672
Ensembl chr12:53,423,855...53,431,672
JBrowse link
G APOA1 apolipoprotein A1 NOT IDA (PMID:23726972) UniProtKB PMID:23726972 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 IMP (PMID:26583432) UniProt PMID:26583432 NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105
JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 IMP (PMID:26583432) UniProt PMID:26583432 NCBI chr12:105,173,297...105,236,174
Ensembl chr12:105,173,297...105,236,203
JBrowse link
G ARHGEF18 Rho/Rac guanine nucleotide exchange factor 18 TAS Reactome Reactome:R-HSA-2173791 NCBI chr19:7,348,901...7,476,990
Ensembl chr19:7,382,834...7,470,241
Ensembl chr19:7,382,834...7,470,241
JBrowse link
G ARRB2 arrestin beta 2 IDA (PMID:12958365) BHF-UCL PMID:12958365 NCBI chr17:4,710,619...4,721,500
Ensembl chr17:4,710,596...4,721,499
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:28,677,521...28,682,932
Ensembl chr10:28,677,510...28,682,932
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A TAS (PMID:8397373) PINC PMID:8397373 NCBI chr10:86,755,786...86,927,969
Ensembl chr10:86,756,601...86,932,838
Ensembl chr10:86,756,601...86,932,838
JBrowse link
G CBL Cbl proto-oncogene TAS Reactome Reactome:R-HSA-2173789 NCBI chr11:119,206,339...119,308,149
Ensembl chr11:119,206,298...119,313,926
Ensembl chr11:119,206,298...119,313,926
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO RGD PMID:14505427 RGD:1582324 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CDH5 cadherin 5 IDA (PMID:21168935) UniProtKB PMID:21168935 NCBI chr16:66,366,657...66,404,784
Ensembl chr16:66,366,622...66,404,784
JBrowse link
G CGN cingulin TAS Reactome Reactome:R-HSA-2173791 NCBI chr 1:151,510,858...151,538,692
Ensembl chr 1:151,510,510...151,538,692
JBrowse link
G CITED1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 IDA (PMID:9707553) BHF-UCL PMID:9707553 NCBI chr  X:72,301,646...72,307,157
Ensembl chr  X:72,301,638...72,307,187
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648
JBrowse link
G CLDN5 claudin 5 IDA (PMID:21168935) UniProtKB PMID:21168935 NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545
JBrowse link
G COL1A2 collagen type I alpha 2 chain IDA (PMID:17217948) UniProtKB PMID:17217948 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
JBrowse link
G COL3A1 collagen type III alpha 1 chain IDA (PMID:16360482) UniProtKB PMID:16360482 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
JBrowse link
G CREB1 cAMP responsive element binding protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G DUSP15 dual specificity phosphatase 15 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:31,845,578...31,870,744
Ensembl chr20:31,847,637...31,870,747
JBrowse link
G DUSP22 dual specificity phosphatase 22 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:292,057...351,355
Ensembl chr 6:291,630...351,355
JBrowse link
G ENG endoglin NOT IDA
IBA
(PMID:18223685)
(PMID:21873635)
(PMID:12015308), (PMID:18223685)
BHF-UCL
GO_Central
PMID:12015308, PMID:18223685, PMID:21873635 NCBI chr 9:127,815,012...127,854,773
Ensembl chr 9:127,815,013...127,854,658
Ensembl chr 9:127,815,013...127,854,658
JBrowse link
G F11R F11 receptor TAS Reactome Reactome:R-HSA-2173791 NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,343
JBrowse link
G FERMT2 fermitin family member 2 IMP (PMID:21325030) UniProtKB PMID:21325030 NCBI chr14:52,857,271...52,951,050
Ensembl chr14:52,857,268...52,952,435
JBrowse link
G FNTA farnesyltransferase, CAAX box, alpha TAS (PMID:8599089) PINC PMID:8599089 NCBI chr 8:43,056,323...43,085,785
Ensembl chr 8:43,034,194...43,085,788
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit IDA (PMID:9732876) BHF-UCL PMID:9732876 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOXH1 forkhead box H1 TAS
IBA
ISS
(PMID:9702198)
(PMID:21873635)
UniProtKB
GO_Central
BHF-UCL
PMID:9702198, PMID:21873635 GO_REF:0000024 NCBI chr 8:144,473,412...144,475,849
Ensembl chr 8:144,473,412...144,475,849
JBrowse link
G FSHB follicle stimulating hormone subunit beta IEP (PMID:14557487) BHF-UCL PMID:14557487 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,016...30,235,261
JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme TAS Reactome Reactome:R-HSA-2173789 NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,458
JBrowse link
G FUT8 fucosyltransferase 8 IEA Ensembl GO_REF:0000107 NCBI chr14:65,410,592...65,744,122
Ensembl chr14:65,410,592...65,744,121
JBrowse link
G GCNT2 glucosaminyl (N-acetyl) transferase 2 (I blood group) IMP (PMID:21750175) UniProtKB PMID:21750175 NCBI chr 6:10,521,283...10,629,368
Ensembl chr 6:10,492,223...10,629,368
JBrowse link
G GDF10 growth differentiation factor 10 TAS (PMID:8679252) PINC PMID:8679252 NCBI chr10:47,300,197...47,313,577
Ensembl chr10:47,300,197...47,313,577
JBrowse link
G GDF15 growth differentiation factor 15 TAS (PMID:9348093) PINC PMID:9348093 NCBI chr19:18,382,170...18,389,176
Ensembl chr19:18,374,731...18,389,176
JBrowse link
G GDF5 growth differentiation factor 5 TAS (PMID:7961761) PINC PMID:7961761 NCBI chr20:35,433,347...35,454,749
Ensembl chr20:35,433,347...35,454,746
JBrowse link
G GDF9 growth differentiation factor 9 TAS (PMID:7760846) PINC PMID:7760846 NCBI chr 5:132,861,181...132,866,884
Ensembl chr 5:132,861,181...132,866,884
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998
JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase IDA (PMID:15574495) UniProtKB PMID:15574495 NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154
JBrowse link
G ID1 inhibitor of DNA binding 1, HLH protein TAS (PMID:14522471) BHF-UCL PMID:14522471 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515
JBrowse link
G ITGB1 integrin subunit beta 1 NOT IMP (PMID:24036928) UniProtKB PMID:24036928 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,900,318...33,005,792
JBrowse link
G ITGB5 integrin subunit beta 5 IMP (PMID:24036928) UniProtKB PMID:24036928 NCBI chr 3:124,761,948...124,901,418
Ensembl chr 3:124,761,948...124,901,418
JBrowse link
G ITGB6 integrin subunit beta 6 ISO (MGI:MGI:6376388|PMID:30952606)
(MGI:MGI:3040752|PMID:12634787)
MGI PMID:12634787, PMID:30952606 MGI:MGI:3040752, MGI:MGI:6376388 NCBI chr 2:160,099,671...160,200,272
Ensembl chr 2:160,099,667...160,200,313
JBrowse link
G ITGB8 integrin subunit beta 8 ISO (MGI:MGI:6376388|PMID:30952606) MGI PMID:30952606 MGI:MGI:6376388 NCBI chr 7:20,329,819...20,415,754
Ensembl chr 7:20,330,702...20,415,754
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit IDA (PMID:9732876) BHF-UCL PMID:9732876 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G LEFTY1 left-right determination factor 1 TAS (PMID:10053005) PINC PMID:10053005 NCBI chr 1:225,886,282...225,889,146
Ensembl chr 1:225,886,282...225,911,382
JBrowse link
G LEFTY2 left-right determination factor 2 TAS (PMID:9153275) PINC PMID:9153275 NCBI chr 1:225,936,603...225,941,367
Ensembl chr 1:225,936,598...225,941,383
JBrowse link
G LPXN leupaxin IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:58,526,871...58,578,239
Ensembl chr11:58,526,871...58,578,220
JBrowse link
G LRRC32 leucine rich repeat containing 32 IDA (PMID:19750484) UniProt PMID:19750484 NCBI chr11:76,657,524...76,670,747
Ensembl chr11:76,657,524...76,670,747
JBrowse link
G LTBP2 latent transforming growth factor beta binding protein 2 TAS (PMID:8697098) PINC PMID:8697098 NCBI chr14:74,498,183...74,612,593
Ensembl chr14:74,498,183...74,612,378
JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 IEA Ensembl GO_REF:0000107 NCBI chr11:65,538,559...65,558,389
Ensembl chr11:65,538,805...65,558,930
JBrowse link
G LTBP4 latent transforming growth factor beta binding protein 4 IEA Ensembl GO_REF:0000107 NCBI chr19:40,593,166...40,629,820
Ensembl chr19:40,592,883...40,629,818
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO (MGI:MGI:2674169|PMID:12941696) MGI PMID:12941696 MGI:MGI:2674169 NCBI chr 5:56,815,543...56,896,152
Ensembl chr 5:56,815,549...56,896,152
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 TAS (PMID:9466656) PINC PMID:9466656 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,072
JBrowse link
G MIR143 microRNA 143 ISO (MGI:MGI:6208917|PMID:29925839) MGI PMID:29925839 MGI:MGI:6208917 NCBI chr 5:149,428,918...149,429,023
Ensembl chr 5:149,428,918...149,429,023
JBrowse link
G MIR145 microRNA 145 ISO (MGI:MGI:6208917|PMID:29925839) MGI PMID:29925839 MGI:MGI:6208917 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733
JBrowse link
G MSTN myostatin IEA Ensembl GO_REF:0000107 NCBI chr 2:190,055,700...190,062,729
Ensembl chr 2:190,055,700...190,062,729
JBrowse link
G MTMR4 myotubularin related protein 4 IEA InterPro GO_REF:0000002 NCBI chr17:58,489,537...58,518,109
Ensembl chr17:58,489,529...58,517,905
JBrowse link
G NLK nemo like kinase IMP (PMID:15004007) UniProtKB PMID:15004007 NCBI chr17:28,042,647...28,205,140
Ensembl chr17:28,041,737...28,196,381
JBrowse link
G NRROS negative regulator of reactive oxygen species ISS UniProt GO_REF:0000024 NCBI chr 3:196,639,694...196,662,004
Ensembl chr 3:196,639,694...196,662,004
JBrowse link
G PARD3 par-3 family cell polarity regulator TAS Reactome Reactome:R-HSA-2173791 NCBI chr10:34,109,561...34,815,296
Ensembl chr10:34,109,560...34,815,325
JBrowse link
G PARD6A par-6 family cell polarity regulator alpha TAS Reactome Reactome:R-HSA-2173791 NCBI chr16:67,660,956...67,662,774
Ensembl chr16:67,660,946...67,662,778
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,691...226,408,093
JBrowse link
G PIAS2 protein inhibitor of activated STAT 2 NOT IDA (PMID:16777850) UniProt PMID:16777850 NCBI chr18:46,803,218...46,920,167
Ensembl chr18:46,803,218...46,920,160
JBrowse link
G PML PML nuclear body scaffold IEA Ensembl GO_REF:0000107 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827
JBrowse link
G PRKCZ protein kinase C zeta TAS Reactome Reactome:R-HSA-2173791 NCBI chr 1:2,050,411...2,185,395
Ensembl chr 1:2,050,411...2,185,395
JBrowse link
G PTK2 protein tyrosine kinase 2 IDA (PMID:24036928) UniProtKB PMID:24036928 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216
JBrowse link
G PTPRK protein tyrosine phosphatase receptor type K IDA (PMID:15899872) UniProtKB PMID:15899872 NCBI chr 6:127,968,785...128,520,603
Ensembl chr 6:127,968,779...128,520,674
JBrowse link
G PXN paxillin IDA
IBA
(PMID:24036928)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:24036928 NCBI chr12:120,210,447...120,265,737
Ensembl chr12:120,210,439...120,265,771
JBrowse link
G RHOA ras homolog family member A TAS Reactome Reactome:R-HSA-2173791 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,145...49,412,998
JBrowse link
G RPS27A ribosomal protein S27a TAS Reactome Reactome:R-HSA-2173791 NCBI chr 2:55,231,903...55,235,853
Ensembl chr 2:55,231,903...55,235,853
JBrowse link
G SIRT1 sirtuin 1 IDA (PMID:23960241) BHF-UCL PMID:23960241 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SKI SKI proto-oncogene NAS (PMID:14583455) BHF-UCL PMID:14583455 NCBI chr 1:2,228,319...2,310,213
Ensembl chr 1:2,228,319...2,310,213
JBrowse link
G SKIL SKI like proto-oncogene IEA Ensembl GO_REF:0000107 NCBI chr 3:170,357,678...170,396,849
Ensembl chr 3:170,357,678...170,396,835
JBrowse link
G SMAD1 SMAD family member 1 IEA
IBA
NAS
(PMID:21873635)
(PMID:8663601)
InterPro
GO_Central
UniProtKB
PMID:8663601, PMID:21873635 GO_REF:0000002 NCBI chr 4:145,481,306...145,559,176
Ensembl chr 4:145,481,194...145,559,176
JBrowse link
G SMAD2 SMAD family member 2 IMP
IBA
IDA
IEA
TAS
(PMID:8980228)
(PMID:21873635)
(PMID:18548003), (PMID:8752209), (PMID:9389648), (PMID:9732876)
BHF-UCL
GO_Central
InterPro
Reactome
PMID:8752209, PMID:8980228, PMID:9389648, PMID:9732876, PMID:18548003, PMID:21873635 GO_REF:0000002, Reactome:R-HSA-2173789 NCBI chr18:47,808,957...47,931,188
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SMAD3 SMAD family member 3 TAS
IBA
IDA
IEA
(PMID:21873635)
(PMID:18548003), (PMID:21947082), (PMID:9732876)
Reactome
GO_Central
BHF-UCL
InterPro
PMID:9732876, PMID:18548003, PMID:21873635, PMID:21947082 GO_REF:0000002, Reactome:R-HSA-2173789 NCBI chr15:67,065,602...67,195,195
Ensembl chr15:67,063,763...67,195,169
JBrowse link
G SMAD4 SMAD family member 4 TAS
IBA
IMP
IDA
ISS
IEA
(PMID:21873635)
(PMID:25514493)
(PMID:9389648), (PMID:9732876)
Reactome
GO_Central
UniProt
BHF-UCL
InterPro
PMID:9389648, PMID:9732876, PMID:21873635, PMID:25514493 GO_REF:0000002, GO_REF:0000024, Reactome:R-HSA-2173789 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,394...51,085,045
JBrowse link
G SMAD5 SMAD family member 5 IEA
IBA
NAS
(PMID:21873635)
(PMID:10708948)
InterPro
GO_Central
UniProtKB
PMID:10708948, PMID:21873635 GO_REF:0000002 NCBI chr 5:136,132,845...136,182,733
Ensembl chr 5:136,132,845...136,188,747
JBrowse link
G SMAD6 SMAD family member 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:66,702,110...66,782,849
Ensembl chr15:66,702,236...66,782,849
JBrowse link
G SMAD7 SMAD family member 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:48,919,853...48,950,711
Ensembl chr18:48,919,853...48,952,052
JBrowse link
G SMAD9 SMAD family member 9 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:36,844,831...36,920,721
Ensembl chr13:36,844,831...36,920,765
JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 TAS Reactome Reactome:R-HSA-2173791 NCBI chr 7:99,027,435...99,144,118
Ensembl chr 7:99,027,438...99,144,100
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase IMP (PMID:24036928) UniProtKB PMID:24036928 NCBI chr20:37,344,690...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 IEA Ensembl GO_REF:0000107 NCBI chr22:39,399,780...39,437,132
Ensembl chr22:39,399,778...39,437,060
JBrowse link
G TGFB1 transforming growth factor beta 1 TAS
IBA
IDA
(PMID:21873635)
(PMID:11157754), (PMID:9389648)
Reactome
GO_Central
BHF-UCL
PMID:9389648, PMID:11157754, PMID:21873635 Reactome:R-HSA-2173789, Reactome:R-HSA-2173791 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFB2 transforming growth factor beta 2 IDA
IBA
(PMID:11157754), (PMID:18358889)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:11157754, PMID:18358889, PMID:21873635 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
JBrowse link
G TGFB3 transforming growth factor beta 3 IDA
IBA
(PMID:11157754), (PMID:18718461)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:11157754, PMID:18718461, PMID:21873635 NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 IC
IBA
IDA
TAS
ISS
IMP
(PMID:1326540)
(PMID:21873635)
(PMID:11157754), (PMID:9389648)
(PMID:1333888)
BHF-UCL
GO_Central
Reactome
AgBase
PMID:1326540, PMID:1333888, PMID:9389648, PMID:11157754, PMID:21873635 GO_REF:0000024, Reactome:R-HSA-2173789, Reactome:R-HSA-2173791 NCBI chr 9:99,104,038...99,154,192
Ensembl chr 9:99,104,038...99,154,192
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 IC
IBA
IMP
TAS
IDA
(PMID:1326540)
(PMID:21873635)
(PMID:11157754), (PMID:1333888)
(PMID:18453574)
BHF-UCL
GO_Central
Reactome
PMID:1326540, PMID:1333888, PMID:11157754, PMID:18453574, PMID:21873635 Reactome:R-HSA-2173789, Reactome:R-HSA-2173791 NCBI chr 3:30,606,472...30,694,142
Ensembl chr 3:30,606,601...30,694,142
Ensembl chr 3:30,606,601...30,694,142
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 IMP
IBA
ISS
IDA
(PMID:11157754)
(PMID:21873635)
(PMID:12958365)
BHF-UCL
GO_Central
PMID:11157754, PMID:12958365, PMID:21873635 GO_REF:0000024 NCBI chr 1:91,680,343...91,906,002
Ensembl chr 1:91,680,343...91,906,335
JBrowse link
G TGFBR3L transforming growth factor beta receptor 3 like IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:7,914,830...7,919,097
Ensembl chr19:7,916,145...7,919,097
JBrowse link
G TGFBRAP1 transforming growth factor beta receptor associated protein 1 TAS (PMID:9545258) UniProtKB PMID:9545258 NCBI chr 2:105,249,404...105,329,735
Ensembl chr 2:105,264,391...105,329,735
JBrowse link
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 IDA (PMID:17164348) BHF-UCL PMID:17164348 NCBI chr18:9,334,773...9,402,420
Ensembl chr18:9,334,767...9,402,420
JBrowse link
G UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 TAS Reactome Reactome:R-HSA-2173791 NCBI chr19:18,563,766...18,577,550
Ensembl chr19:18,571,730...18,577,550
JBrowse link
G UBB ubiquitin B TAS Reactome Reactome:R-HSA-2173791 NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745
JBrowse link
G UBC ubiquitin C TAS Reactome Reactome:R-HSA-2173791 NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368
JBrowse link
G USP15 ubiquitin specific peptidase 15 IDA
IMP
(PMID:21947082)
(PMID:22344298)
UniProtKB PMID:21947082, PMID:22344298 NCBI chr12:62,260,404...62,416,389
Ensembl chr12:62,260,338...62,417,431
JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked IMP (PMID:19135894) UniProtKB PMID:19135894 NCBI chr  X:41,085,420...41,236,579
Ensembl chr  X:41,085,445...41,236,579
JBrowse link
G USP9Y ubiquitin specific peptidase 9 Y-linked ISS UniProtKB GO_REF:0000024 NCBI chr  Y:12,701,231...12,860,839
Ensembl chr  Y:12,537,650...12,860,839
JBrowse link
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 ISS (PMID:12595574) UniProtKB PMID:12595574 NCBI chr17:50,834,584...50,842,353
Ensembl chr17:50,834,650...50,842,353
JBrowse link
G ZFYVE9 zinc finger FYVE-type containing 9 TAS
IBA
IMP
NAS
(PMID:21873635)
(PMID:9865696)
(PMID:10615055)
Reactome
GO_Central
UniProtKB
PMID:9865696, PMID:10615055, PMID:21873635 Reactome:R-HSA-2173789 NCBI chr 1:52,142,001...52,348,664
Ensembl chr 1:52,142,094...52,346,686
JBrowse link
G ZMIZ1 zinc finger MIZ-type containing 1 IDA (PMID:16777850) UniProt PMID:16777850 NCBI chr10:79,068,966...79,316,519
Ensembl chr10:79,068,966...79,316,528
JBrowse link
G ZMIZ2 zinc finger MIZ-type containing 2 NOT IDA (PMID:16777850) UniProt PMID:16777850 NCBI chr 7:44,748,547...44,769,881
Ensembl chr 7:44,748,581...44,769,881
JBrowse link
G ZYX zyxin IMP
IBA
(PMID:24036928)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:24036928 NCBI chr 7:143,381,345...143,391,111
Ensembl chr 7:143,381,295...143,391,111
JBrowse link
transforming growth factor beta receptor signaling pathway involved in heart development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFB1 transforming growth factor beta 1 ISS
IEA
BHF-UCL
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
transforming growth factor beta receptor signaling pathway involved in primitive streak formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NODAL nodal growth differentiation factor IEA Ensembl GO_REF:0000107 NCBI chr10:70,431,936...70,447,951
Ensembl chr10:70,431,936...70,447,951
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18626
    response to stimulus 10122
      response to endogenous stimulus 2161
        response to transforming growth factor beta 296
          cellular response to transforming growth factor beta stimulus + 288
Path 2
Term Annotations click to browse term
  biological_process 18626
    response to stimulus 10122
      response to chemical 5615
        response to organic substance 4176
          response to growth factor 867
            response to transforming growth factor beta 296
              cellular response to transforming growth factor beta stimulus + 288
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.