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ONTOLOGY REPORT - ANNOTATIONS


Term:response to transforming growth factor beta
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Accession:GO:0071559 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
Synonyms:exact_synonym: response to TGF-beta stimulus;   response to TGFbeta stimulus;   response to transforming growth factor beta stimulus


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response to transforming growth factor beta term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cald1 caldesmon 1 NOT ISO (MGI:MGI:5582864|PMID:24036928) UniProtKB PMID:24036928 MGI:MGI:5582864 NCBI chrNW_004936579:868,681...1,046,198 JBrowse link
G Cited1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 ISO (PMID:9707553) UniProtKB PMID:9707553 NCBI chrNW_004936762:1,387,354...1,392,955 JBrowse link
G Dspp dentin sialophosphoprotein ISO RGD PMID:22012415 RGD:12914763 NCBI chrNW_004936905:458,062...463,359 JBrowse link
G Edn1 endothelin 1 ISO RGD PMID:11061980 RGD:8662323 NCBI chrNW_004936534:885,489...892,292 JBrowse link
G Eng endoglin ISO RGD PMID:22941949 RGD:7248789 NCBI chrNW_004936487:15,467,165...15,499,180 JBrowse link
G Fndc4 fibronectin type III domain containing 4 ISO (PMID:27066907) UniProtKB PMID:27066907 NCBI chrNW_004936493:5,103,613...5,106,755 JBrowse link
G Gdf10 growth differentiation factor 10 ISO RGD PMID:10079200 RGD:2316373 NCBI chrNW_004936554:7,292,805...7,307,001 JBrowse link
G Il1r1 interleukin 1 receptor type 1 ISO RGD PMID:9233842 RGD:8662880 NCBI chrNW_004936713:808,761...881,070 JBrowse link
G Itgb1 integrin subunit beta 1 ISO TGF-beta2 RGD PMID:18378961 RGD:2325302 NCBI chrNW_004936574:1,465,981...1,495,717 JBrowse link
G Men1 menin 1 ISO RGD PMID:15054094 RGD:1304318 NCBI chrNW_004936599:4,504,489...4,510,085 JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming ISO RGD PMID:15980276 RGD:8693640 NCBI chrNW_004936816:60,499...91,628 JBrowse link
G Mxra5 matrix remodeling associated 5 ISO (PMID:27599751) UniProtKB PMID:27599751 NCBI chrNW_004936644:2,502,334...2,528,278 JBrowse link
G Rock1 Rho associated coiled-coil containing protein kinase 1 ISO (MGI:MGI:6158813|PMID:28679962) ARUK-UCL PMID:28679962 MGI:MGI:6158813, RGD:13601991 NCBI chrNW_004936550:730,462...874,601 JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 ISO (MGI:MGI:6158813|PMID:28679962) ARUK-UCL PMID:28679962 MGI:MGI:6158813, RGD:13601991 NCBI chrNW_004936532:7,142,580...7,284,722 JBrowse link
G Runx3 RUNX family transcription factor 3 ISO (PMID:20599712) UniProtKB PMID:20599712 NCBI chrNW_004936474:9,751,946...9,802,910 JBrowse link
G Serpine1 serpin family E member 1 ISO RGD PMID:16105028 RGD:8547842 NCBI chrNW_004936543:1,032,543...1,040,956 JBrowse link
G Smad4 SMAD family member 4 ISO (PMID:9707553) UniProtKB PMID:9707553 NCBI chrNW_004936497:12,242,869...12,278,012 JBrowse link
G Zfhx3 zinc finger homeobox 3 ISO (PMID:20599712) UniProtKB PMID:20599712 NCBI chrNW_004936475:21,005,242...21,235,992 JBrowse link
cellular response to transforming growth factor beta stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO RGD PMID:15629889 RGD:8693572 NCBI chrNW_004936487:17,690,206...17,819,619 JBrowse link
G Actr3 actin related protein 3 ISO RGD PMID:22319661 RGD:11530045 NCBI chrNW_004936469:55,639,345...55,699,330 JBrowse link
G Acvrl1 activin A receptor like type 1 ISO (MGI:MGI:3848261|PMID:19494318)
(PMID:19494318)
BHF-UCL PMID:19494318 MGI:MGI:3848261 NCBI chrNW_004936512:9,364,551...9,379,131 JBrowse link
G Ankrd1 ankyrin repeat domain 1 ISO (PMID:11139470) BHF-UCL PMID:11139470 NCBI chrNW_004936601:3,502,844...3,510,919 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO RGD PMID:11003619 RGD:2325753 NCBI chrNW_004936492:14,818,561...14,902,231 JBrowse link
G Cav1 caveolin 1 ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chrNW_004936589:2,504,235...2,536,778 JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO RGD PMID:20429874 RGD:4889909 NCBI chrNW_004936490:253,279...259,947 JBrowse link
G Cilp cartilage intermediate layer protein ISO (PMID:29167509) BHF-UCL PMID:29167509 NCBI chrNW_004936471:25,501,538...25,517,033 JBrowse link
G Cldn1 claudin 1 ISO RGD PMID:18031476 RGD:11344898 NCBI chrNW_004936578:98,489...113,125 JBrowse link
G Clec3b C-type lectin domain family 3 member B ISO (PMID:7589422) UniProtKB PMID:7589422 NCBI chrNW_004936695:731,184...738,752 JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO PMID:19362560 RGD
UniProt
PMID:19362560, PMID:23560091 RGD:8552683, RGD:8554531 NCBI chrNW_004936490:11,448,552...11,465,836 JBrowse link
G Col4a2 collagen type IV alpha 2 chain ISO (PMID:17525254) UniProtKB PMID:17525254 NCBI chrNW_004936472:2,270,836...2,416,324 JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO RGD PMID:21308733 RGD:10059386 NCBI chrNW_004936631:3,721,307...3,785,346 JBrowse link
G Crk CRK proto-oncogene, adaptor protein ISO RGD PMID:12837295 RGD:11568682 NCBI chrNW_004936538:7,581,453...7,609,543 JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein ISO (PMID:23959425) ARUK-UCL PMID:23959425 NCBI chrNW_004936619:2,447,686...2,479,589 JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:12446007 RGD:4892023 NCBI chrNW_004936473:28,508,726...28,535,640 JBrowse link
G Dab2 DAB adaptor protein 2 ISO (MGI:MGI:5442512|PMID:15894542), (MGI:MGI:5442513|PMID:15734730) RGD
UniProtKB
PMID:15734730, PMID:15894542, PMID:21762377 MGI:MGI:5442512, MGI:MGI:5442513, RGD:7243156 NCBI chrNW_004936518:2,915,819...2,936,474 JBrowse link
G Dbn1 drebrin 1 ISO RGD PMID:22319661 RGD:11530045 NCBI chrNW_004936597:1,735,589...1,751,628 JBrowse link
G Dlx1 distal-less homeobox 1 ISO (PMID:14671321) UniProtKB PMID:14671321 NCBI chrNW_004936509:2,248,181...2,250,991 JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO RGD PMID:24211420 RGD:9588224 NCBI chrNW_004936659:520,181...565,496 JBrowse link
G Edn1 endothelin 1 ISO RGD PMID:8439651 RGD:8662306 NCBI chrNW_004936534:885,489...892,292 JBrowse link
G Eln elastin ISO RGD PMID:9224206 RGD:9585659 NCBI chrNW_004936543:3,135,169...3,165,023 JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 ISO (MGI:MGI:3821807|PMID:18794329) MGI PMID:18794329 MGI:MGI:3821807 NCBI chrNW_004936469:50,329,564...50,443,532 JBrowse link
G Fbn1 fibrillin 1 ISO RGD PMID:11012893 RGD:7387263 NCBI chrNW_004936471:10,747,030...10,969,223 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO RGD PMID:12648559 RGD:12801436 NCBI chrNW_004936486:10,506,680...10,606,272 JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:16669970 RGD:1626090 NCBI chrNW_004936586:1,708,803...1,773,372 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chrNW_004936679:388,500...588,518 JBrowse link
G Hdac2 histone deacetylase 2 ISO RGD PMID:19553350 RGD:9590229 NCBI chrNW_004936679:2,448,676...2,474,641 JBrowse link
G Hyal2 hyaluronidase 2 ISO (PMID:19366691)
(MGI:MGI:3851310|PMID:19366691)
BHF-UCL PMID:19366691 MGI:MGI:3851310 NCBI chrNW_004936529:1,845,445...1,851,106 JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO RGD PMID:16628634 RGD:9686088 NCBI chrNW_004936485:18,610,721...18,611,889 JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO RGD PMID:12837295 RGD:11568682 NCBI chrNW_004936483:4,563,995...4,860,231 JBrowse link
G L1cam L1 cell adhesion molecule ISO RGD PMID:16686695 RGD:6483452 NCBI chrNW_004936809:736,385...768,822 JBrowse link
G Lims1 LIM zinc finger domain containing 1 ISO (PMID:21390327) UniProtKB PMID:21390327 NCBI chrNW_004936829:187,234...240,213 JBrowse link
G LOC101964456 ectonucleotide pyrophosphatase/phosphodiesterase family member 1 ISO RGD PMID:24157151 RGD:13204713 NCBI chrNW_004937067:194,375...246,607 JBrowse link
G LOC101970885 lymphotactin ISO (MGI:MGI:85739|PMID:9013979) BHF-UCL PMID:9013979 MGI:MGI:85739 NCBI chrNW_004936481:17,825,714...17,828,955 JBrowse link
G LOC101975820 cholesterol side-chain cleavage enzyme, mitochondrial ISO FSH-stimulated granulosa cells RGD PMID:18511507 RGD:4781450 NCBI chrNW_004936471:33,367,810...33,380,764 JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO (PMID:18588859) UniProtKB PMID:18588859 NCBI chrNW_004936881:372,713...377,655 JBrowse link
G Mef2c myocyte enhancer factor 2C ISO (PMID:9770491) UniProtKB PMID:9770491 NCBI chrNW_004936469:7,060,480...7,225,497 JBrowse link
G Muc4 mucin 4, cell surface associated ISO RGD PMID:9857062 RGD:2324952 NCBI chrNW_004936784:515,608...539,915 JBrowse link
G Nos3 nitric oxide synthase 3 ISO RGD PMID:21792926 RGD:8662393 NCBI chrNW_004936527:6,427,147...6,445,770 JBrowse link
G Nox4 NADPH oxidase 4 ISO RGD PMID:18845355 RGD:2324663 NCBI chrNW_004936736:230,465...394,859 JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO (PMID:12902338) CAFA PMID:12902338 NCBI chrNW_004936504:10,960,069...11,056,834 JBrowse link
G Ovol2 ovo like zinc finger 2 ISO (MGI:MGI:6284898|PMID:28455959) ARUK-UCL PMID:28455959 MGI:MGI:6284898 NCBI chrNW_004936485:2,096,495...2,128,002 JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:22073128 RGD:8554355 NCBI chrNW_004936526:3,102,468...3,147,601 JBrowse link
G Pdcd5 programmed cell death 5 ISO (PMID:24012345) UniProtKB PMID:24012345 NCBI chrNW_004936570:3,103,223...3,109,399 JBrowse link
G Pde2a phosphodiesterase 2A ISO (PMID:17704206) UniProtKB PMID:17704206 NCBI chrNW_004936498:1,856,256...1,944,405 JBrowse link
G Pde3a phosphodiesterase 3A ISO (PMID:17704206) UniProtKB PMID:17704206 NCBI chrNW_004936548:5,758,634...6,072,195 JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO RGD PMID:16039137 RGD:1581755 NCBI chrNW_004936754:808,894...828,554 JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:23585135 RGD:9854632 NCBI chrNW_004936551:3,974,140...4,197,852 JBrowse link
G Pdia3 protein disulfide isomerase family A member 3 ISO RGD PMID:15862831 RGD:9999173 NCBI chrNW_004936471:6,809,181...6,834,189 JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:18466611 RGD:2311658 NCBI chrNW_004936541:4,873,459...4,919,787 JBrowse link
G Penk proenkephalin ISO RGD PMID:8584038 RGD:10003035 NCBI chrNW_004936496:3,016,247...3,021,726 JBrowse link
G Postn periostin ISO RGD PMID:22886209 RGD:10040993 NCBI chrNW_004936472:31,644,778...31,677,572 JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO with follicle-stimulating hormone RGD PMID:18511507 RGD:4781450 NCBI chrNW_004936477:4,881,230...5,488,208 JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent 1A ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chrNW_004936495:4,542,576...4,560,603 JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chrNW_004936470:10,379,855...10,578,531 JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 ISO RGD PMID:23845590 RGD:9835377 NCBI chrNW_004936512:5,636,197...5,659,606 JBrowse link
G Rock1 Rho associated coiled-coil containing protein kinase 1 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chrNW_004936550:730,462...874,601 JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chrNW_004936532:7,142,580...7,284,722 JBrowse link
G Scx scleraxis bHLH transcription factor ISO (PMID:18498113), (PMID:9328840) UniProtKB PMID:9328840, PMID:18498113 NCBI chrNW_004936470:7,966,096...7,972,379 JBrowse link
G Serpine1 serpin family E member 1 ISO (MGI:MGI:5289760|PMID:21829547) RGD
MGI
PMID:19247458, PMID:21829547 MGI:MGI:5289760, RGD:8547745 NCBI chrNW_004936543:1,032,543...1,040,956 JBrowse link
G Sfrp1 secreted frizzled related protein 1 ISO (PMID:16149051) UniProtKB PMID:16149051 NCBI chrNW_004936785:1,276,478...1,320,397 JBrowse link
G Smad3 SMAD family member 3 ISO (PMID:12902338) CAFA PMID:12902338 NCBI chrNW_004936471:27,080,662...27,185,861 JBrowse link
G Smad7 SMAD family member 7 ISO (MGI:MGI:5532916|PMID:18593713)
(PMID:18593713)
BHF-UCL PMID:18593713 MGI:MGI:5532916 NCBI chrNW_004936497:13,894,586...13,921,978 JBrowse link
G Snrnp70 small nuclear ribonucleoprotein U1 subunit 70 ISO RGD PMID:10022522 RGD:10448942 NCBI chrNW_004936664:3,035,679...3,054,577 JBrowse link
G Sox5 SRY-box transcription factor 5 ISO (PMID:21401405) UniProtKB PMID:21401405 NCBI chrNW_004936548:3,213,305...3,599,876 JBrowse link
G Sox6 SRY-box transcription factor 6 ISO (PMID:21401405) UniProtKB PMID:21401405 NCBI chrNW_004936528:2,331,706...2,912,423 JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (PMID:17525254)
(PMID:21401405)
UniProtKB PMID:17525254, PMID:21401405 NCBI chrNW_004936655:1,849,044...1,852,648 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO (MGI:MGI:5289760|PMID:21829547) MGI PMID:21829547 MGI:MGI:5289760 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
G Star steroidogenic acute regulatory protein ISO FSH-stimulated granulosa cells RGD PMID:18511507 RGD:4781450 NCBI chrNW_004936710:1,523,289...1,530,181 JBrowse link
G Stk16 serine/threonine kinase 16 ISO RGD PMID:10947953 RGD:727297 NCBI chrNW_004936569:1,664,031...1,667,648 JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO (PMID:19736306), (PMID:22269326)
(PMID:22269326)
(MGI:MGI:5532214|PMID:23861879)
BHF-UCL
MGI
PMID:19736306, PMID:22269326, PMID:23861879 MGI:MGI:5532214 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 ISO (MGI:MGI:3848261|PMID:19494318)
(PMID:19494318)
BHF-UCL PMID:19494318 MGI:MGI:3848261 NCBI chrNW_004936524:7,656,523...7,680,043 JBrowse link
G Usp9x ubiquitin specific peptidase 9 X-linked ISO (MGI:MGI:5532214|PMID:23861879) MGI PMID:23861879 MGI:MGI:5532214 NCBI chrNW_004936502:7,649,808...7,732,731 JBrowse link
G Wnt10a Wnt family member 10A ISO (PMID:15040835) UniProtKB PMID:15040835 NCBI chrNW_004936569:1,309,140...1,321,923 JBrowse link
G Wnt2 Wnt family member 2 ISO (PMID:15040835) UniProtKB PMID:15040835 NCBI chrNW_004936589:1,825,209...1,866,898 JBrowse link
G Wnt4 Wnt family member 4 ISO (PMID:15040835) UniProtKB PMID:15040835 NCBI chrNW_004936474:7,623,462...7,635,416 JBrowse link
G Wnt5a Wnt family member 5A ISO (PMID:15040835) UniProtKB PMID:15040835 NCBI chrNW_004936473:6,031,627...6,052,211 JBrowse link
G Wnt7a Wnt family member 7A ISO (PMID:15040835) UniProtKB PMID:15040835 NCBI chrNW_004936898:45,903...70,313 JBrowse link
G Wwox WW domain containing oxidoreductase ISO (MGI:MGI:3851310|PMID:19366691)
(PMID:19366691)
BHF-UCL PMID:19366691 MGI:MGI:3851310 NCBI chrNW_004936475:26,342,245...27,209,563 JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 ISO RGD PMID:16824956 RGD:2325877 NCBI chrNW_004936574:17,643...175,762 JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 ISO (PMID:20166898) UniProtKB PMID:20166898 NCBI chrNW_004936495:12,045,679...12,050,737 JBrowse link
G Zfp36l2 ZFP36 ring finger protein like 2 ISO (PMID:20166898) UniProtKB PMID:20166898 NCBI chrNW_004936508:8,617,185...8,620,823 JBrowse link
negative regulation of cellular response to transforming growth factor beta stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cflar CASP8 and FADD like apoptosis regulator ISO RGD PMID:18314484 RGD:11341711 NCBI chrNW_004936726:381,888...425,565 JBrowse link
G Dlx1 distal-less homeobox 1 ISO (PMID:14671321) UniProtKB PMID:14671321 NCBI chrNW_004936509:2,248,181...2,250,991 JBrowse link
G Il4 interleukin 4 ISO (PMID:11967989) UniProt PMID:11967989 NCBI chrNW_004936647:2,510,457...2,518,576 JBrowse link
negative regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO (PMID:21170088) UniProtKB PMID:21170088 NCBI chrNW_004936532:5,864,851...5,904,005 JBrowse link
G Adamtsl2 ADAMTS like 2 ISO (MGI:MGI:5638958|PMID:25762570)
(PMID:18677313)
MGI
BHF-UCL
PMID:18677313, PMID:25762570 MGI:MGI:5638958 NCBI chrNW_004936669:3,363,991...3,397,099 JBrowse link
G Aspn asporin ISO (PMID:17827158)
(MGI:MGI:3762064|PMID:17827158)
UniProtKB PMID:17827158 MGI:MGI:3762064 NCBI chrNW_004936487:2,080,014...2,104,534 JBrowse link
G Bambi BMP and activin membrane bound inhibitor ISO (PMID:14660579)
(PMID:19328798)
BHF-UCL PMID:14660579, PMID:19328798 NCBI chrNW_004936613:3,098,549...3,103,868 JBrowse link
G Bcl9l BCL9 like ISO (PMID:19328798) BHF-UCL PMID:19328798 NCBI chrNW_004936542:3,873,530...3,902,871 JBrowse link
G Cav1 caveolin 1 ISO (PMID:25893292) UniProtKB PMID:25893292 NCBI chrNW_004936589:2,504,235...2,536,778 JBrowse link
G Cav2 caveolin 2 ISO (MGI:MGI:5298182|PMID:21832243) MGI PMID:21832243 MGI:MGI:5298182 NCBI chrNW_004936589:2,553,932...2,561,186 JBrowse link
G Cd109 CD109 molecule ISO (PMID:16754747) UniProtKB PMID:16754747 NCBI chrNW_004936859:467,958...595,337 JBrowse link
G Chst11 carbohydrate sulfotransferase 11 ISO (MGI:MGI:3767479|PMID:16079159) MGI PMID:16079159 MGI:MGI:3767479 NCBI chrNW_004936492:9,886,269...10,092,725 JBrowse link
G Cidea cell death inducing DFFA like effector a ISO (MGI:MGI:3768618|PMID:17080483) BHF-UCL PMID:17080483 MGI:MGI:3768618 NCBI chrNW_004936626:230,372...246,893 JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 ISO (MGI:MGI:3055566|PMID:14721776) MGI PMID:14721776 MGI:MGI:3055566 NCBI chrNW_004936659:2,022,657...2,025,353 JBrowse link
G Dnm2 dynamin 2 ISO RGD PMID:25100282 RGD:9685289 NCBI chrNW_004936659:957,408...1,046,393 JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 ISO (PMID:14612439) HGNC PMID:14612439 NCBI chrNW_004936661:2,364,179...2,366,739 JBrowse link
G Emilin1 elastin microfibril interfacer 1 ISO (MGI:MGI:5605894|PMID:25056700) BHF-UCL PMID:25056700 MGI:MGI:5605894 NCBI chrNW_004936493:5,455,369...5,463,205 JBrowse link
G Glg1 golgi glycoprotein 1 ISO (MGI:MGI:4829577|PMID:20530870) MGI PMID:20530870 MGI:MGI:4829577 NCBI chrNW_004936475:23,411,194...23,534,692 JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO (PMID:24613385) UniProtKB PMID:24613385 NCBI chrNW_004936727:1,732,323...1,735,128 JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO (PMID:24613385) UniProtKB PMID:24613385 NCBI chrNW_004936727:1,718,952...1,721,691 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO (MGI:MGI:3771280|PMID:17991893) MGI PMID:17991893 MGI:MGI:3771280 NCBI chrNW_004936487:13,348,465...13,352,717 JBrowse link
G Htra1 HtrA serine peptidase 1 ISO (MGI:MGI:3034116|PMID:14973287) MGI PMID:14973287 MGI:MGI:3034116 NCBI chrNW_004936486:11,271,130...11,317,271 JBrowse link
G Htra3 HtrA serine peptidase 3 ISO (MGI:MGI:3046453|PMID:15206957) UniProtKB PMID:15206957 MGI:MGI:3046453 NCBI chrNW_004936477:19,625,479...19,662,532 JBrowse link
G Il17rd interleukin 17 receptor D ISO (MGI:MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:MGI:6414689 NCBI chrNW_004936473:7,447,292...7,507,819 JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 ISO (PMID:24627487)
(MGI:MGI:5583005|PMID:24627487)
UniProtKB PMID:24627487 MGI:MGI:5583005 NCBI chrNW_004936626:2,730,689...3,088,527 JBrowse link
G Lemd3 LEM domain containing 3 ISO (PMID:15647271) UniProtKB PMID:15647271 NCBI chrNW_004936545:3,385,821...3,453,861 JBrowse link
G Mecom MDS1 and EVI1 complex locus NOT ISO (PMID:15897867) UniProt PMID:15897867 NCBI chrNW_004936593:2,742,236...3,282,596 JBrowse link
G Nkx2-1 NK2 homeobox 1 ISO (PMID:19293183) UniProtKB PMID:19293183 NCBI chrNW_004936494:10,517,488...10,520,567 JBrowse link
G Onecut1 one cut homeobox 1 ISO (MGI:MGI:3588024|PMID:16103213) MGI PMID:16103213 MGI:MGI:3588024 NCBI chrNW_004936471:14,532,888...14,581,258 JBrowse link
G Onecut2 one cut homeobox 2 ISO (MGI:MGI:3588024|PMID:16103213) MGI PMID:16103213 MGI:MGI:3588024 NCBI chrNW_004936497:6,853,739...6,896,408 JBrowse link
G Pbld phenazine biosynthesis like protein domain containing ISO (PMID:23687415) UniProtKB PMID:23687415 NCBI chrNW_004936521:9,943,061...9,998,421 JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 ISO (PMID:17327236) UniProtKB PMID:17327236 NCBI chrNW_004936694:1,444,819...1,487,628 JBrowse link
G Peg10 paternally expressed 10 ISO (PMID:15611116) HGNC PMID:15611116 NCBI chrNW_004936585:5,437,807...5,451,185 JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO (PMID:19122240) BHF-UCL PMID:19122240 NCBI chrNW_004936659:309,530...321,294 JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 ISO (PMID:20129061)
(PMID:24627487)
(MGI:MGI:5582164|PMID:20129061)
UniProtKB PMID:20129061, PMID:24627487 MGI:MGI:5582164 NCBI chrNW_004936530:429,059...439,847 JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent 1A ISO (PMID:16751101) UniProtKB PMID:16751101 NCBI chrNW_004936495:4,542,576...4,560,603 JBrowse link
G Prdm16 PR/SET domain 16 NOT ISO (PMID:19049980)
(MGI:MGI:4430027|PMID:20007998)
(PMID:14656887)
UniProtKB
MGI
PMID:14656887, PMID:19049980, PMID:20007998 MGI:MGI:4430027 NCBI chrNW_004936737:400,819...446,768 JBrowse link
G Rasl11b RAS like family 11 member B ISO (MGI:MGI:3505646|PMID:15239668) MGI PMID:15239668 MGI:MGI:3505646 NCBI chrNW_004936482:15,731,822...15,736,195 JBrowse link
G Sirt1 sirtuin 1 ISO (MGI:MGI:5306300|PMID:17098745) UniProtKB PMID:17098745 MGI:MGI:5306300 NCBI chrNW_004936521:10,296,097...10,316,673 JBrowse link
G Ski SKI proto-oncogene ISO (PMID:17054724), (PMID:19049980)
(MGI:MGI:5300220|PMID:21937600)
(PMID:15312649)
(PMID:17469184)
UniProtKB
MGI
PMID:15312649, PMID:17054724, PMID:17469184, PMID:19049980, PMID:21937600 MGI:MGI:5300220 NCBI chrNW_004936737:1,223,653...1,274,664 JBrowse link
G Skil SKI like proto-oncogene ISO (PMID:17469184), (PMID:19383336)
(MGI:MGI:3530729|PMID:15677329)
UniProtKB
MGI
PMID:15677329, PMID:17469184, PMID:19383336 MGI:MGI:3530729 NCBI chrNW_004936593:2,109,414...2,132,871 JBrowse link
G Skor2 SKI family transcriptional corepressor 2 NOT ISO (MGI:MGI:5300220|PMID:21937600)
(PMID:16200078)
MGI
UniProtKB
PMID:16200078, PMID:21937600 MGI:MGI:5300220 NCBI chrNW_004936983:156,466...197,281 JBrowse link
G Slc2a10 solute carrier family 2 member 10 ISO (PMID:16550171), (PMID:26376865) ARUK-UCL PMID:16550171, PMID:26376865 NCBI chrNW_004936514:6,490,728...6,504,152 JBrowse link
G Smad6 SMAD family member 6 ISO (PMID:19047146)
(PMID:9256479)
BHF-UCL PMID:9256479, PMID:19047146 NCBI chrNW_004936471:26,781,420...26,856,556 JBrowse link
G Smad7 SMAD family member 7 ISO (PMID:12151385), (PMID:17438144), (PMID:18762808), (PMID:9256479) BHF-UCL PMID:9256479, PMID:12151385, PMID:17438144, PMID:18762808 NCBI chrNW_004936497:13,894,586...13,921,978 JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO (PMID:11278251), (PMID:12151385) BHF-UCL PMID:11278251, PMID:12151385 NCBI chrNW_004936750:1,381,864...1,406,736 JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 ISO (PMID:19255252) CACAO PMID:19255252 NCBI chrNW_004936541:5,046,147...5,147,416 JBrowse link
G Snx1 sorting nexin 1 ISO (MGI:MGI:3505646|PMID:15239668) MGI PMID:15239668 MGI:MGI:3505646 NCBI chrNW_004936471:24,569,677...24,617,016 JBrowse link
G Snx25 sorting nexin 25 ISO (PMID:21266196)
(MGI:MGI:5545984|PMID:21266196)
UniProtKB PMID:21266196 MGI:MGI:5545984 NCBI chrNW_004936554:3,982,755...4,093,143 JBrowse link
G Snx6 sorting nexin 6 ISO (PMID:11279102) HGNC PMID:11279102 NCBI chrNW_004936494:8,819,695...8,880,298 JBrowse link
G Spred1 sprouty related EVH1 domain containing 1 ISO (MGI:MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:MGI:6414689 NCBI chrNW_004936471:1,952,532...2,039,561 JBrowse link
G Spred2 sprouty related EVH1 domain containing 2 ISO (MGI:MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:MGI:6414689 NCBI chrNW_004936491:10,053,546...10,170,950 JBrowse link
G Spred3 sprouty related EVH1 domain containing 3 ISO (MGI:MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:MGI:6414689 NCBI chrNW_004936801:1,150,897...1,160,016 JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 ISO (MGI:MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:MGI:6414689 NCBI chrNW_004936662:2,241,928...2,245,616 JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 ISO (MGI:MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:MGI:6414689 NCBI chrNW_004936511:1,452,421...1,458,031 JBrowse link
G Strap serine/threonine kinase receptor associated protein ISO (PMID:23687415)
(MGI:MGI:1321347|PMID:9856985)
UniProtKB
MGI
PMID:9856985, PMID:23687415 MGI:MGI:1321347 NCBI chrNW_004936587:1,679,570...1,700,610 JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 ISO (PMID:24613385) UniProtKB PMID:24613385 NCBI chrNW_004936501:328,767...330,963 JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 ISO (MGI:MGI:3771280|PMID:17991893) MGI PMID:17991893 MGI:MGI:3771280 NCBI chrNW_004936596:451,483...453,892 JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 ISO (PMID:18762808) BHF-UCL PMID:18762808 NCBI chrNW_004936543:8,347,343...8,352,909 JBrowse link
G Tgfb3 transforming growth factor beta 3 ISO RGD PMID:12071374 RGD:730235 NCBI chrNW_004936488:4,986,712...5,008,728 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO RGD PMID:10746731 RGD:1579946 NCBI chrNW_004936537:7,154,125...7,340,218 JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:3528807|PMID:15657445) MGI PMID:15657445 MGI:MGI:3528807 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Vasn vasorin ISO (PMID:21170088)
(PMID:15247411)
UniProtKB PMID:15247411, PMID:21170088 NCBI chrNW_004936694:128,398...138,954 JBrowse link
G Veph1 ventricular zone expressed PH domain containing 1 ISO (PMID:26039994) UniProt PMID:26039994 NCBI chrNW_004936519:4,143,036...4,359,329 JBrowse link
G Wfikkn1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 ISO (PMID:21054789) UniProtKB PMID:21054789 NCBI chrNW_004936501:371,328...375,271 JBrowse link
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 ISO (PMID:21054789) UniProtKB PMID:21054789 NCBI chrNW_004936490:10,897,390...10,903,605 JBrowse link
G Wnt1 Wnt family member 1 ISO (MGI:MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:MGI:3628833 NCBI chrNW_004936512:6,781,001...6,785,358 JBrowse link
G Xbp1 X-box binding protein 1 ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chrNW_004936657:2,891,171...2,895,409 JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7A ISO (PMID:25514493) UniProt PMID:25514493 NCBI chrNW_004936588:2,310,975...2,321,790 JBrowse link
G Znf451 zinc finger protein 451 ISO (PMID:24324267) UniProtKB PMID:24324267 NCBI chrNW_004936476:4,133,803...4,268,834 JBrowse link
positive regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO (MGI:MGI:3829110|PMID:18625725) BHF-UCL PMID:18625725 MGI:MGI:3829110 NCBI chrNW_004936532:5,864,851...5,904,005 JBrowse link
G Axin1 axin 1 ISO (MGI:MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:MGI:3628833 NCBI chrNW_004936501:599,963...633,837 JBrowse link
G Cited2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO (MGI:MGI:3690196|PMID:16619037) UniProtKB PMID:16619037 MGI:MGI:3690196 NCBI chrNW_004936560:6,353,901...6,356,749 JBrowse link
G Crebbp CREB binding protein ISO (PMID:25514493) UniProt PMID:25514493 NCBI chrNW_004936694:552,447...663,237 JBrowse link
G Ep300 E1A binding protein p300 ISO (PMID:25514493) UniProt PMID:25514493 NCBI chrNW_004936492:696,982...778,132 JBrowse link
G Fermt1 fermitin family member 1 ISO (MGI:MGI:5571208|PMID:24681597) CAFA PMID:24681597 MGI:MGI:5571208 NCBI chrNW_004936485:12,985,552...13,016,997 JBrowse link
G Flcn folliculin ISO (PMID:20573232)
(MGI:MGI:5050037|PMID:21258407)
UniProtKB
MGI
PMID:20573232, PMID:21258407 MGI:MGI:5050037 NCBI chrNW_004936741:881,150...901,296 JBrowse link
G Furin furin, paired basic amino acid cleaving enzyme ISO RGD PMID:15194465 RGD:1582619 NCBI chrNW_004936483:16,136,099...16,147,945 JBrowse link
G Gipc1 GIPC PDZ domain containing family member 1 ISO (MGI:MGI:3807767|PMID:11546783) BHF-UCL PMID:11546783 MGI:MGI:3807767 NCBI chrNW_004936659:3,019,829...3,030,280 JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:26880260 RGD:13504840 NCBI chrNW_004936636:617,376...640,424 JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 ISO (PMID:14678985) UniProtKB PMID:14678985 NCBI chrNW_004936592:3,800,619...3,934,347 JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO (PMID:24613385) UniProtKB PMID:24613385 NCBI chrNW_004936476:15,830,459...15,836,994 JBrowse link
G Ing2 inhibitor of growth family member 2 ISO (PMID:18334480) UniProtKB PMID:18334480 NCBI chrNW_004936554:5,585,953...5,593,536 JBrowse link
G Itga8 integrin subunit alpha 8 ISO (MGI:MGI:3714574|PMID:17537792) MGI PMID:17537792 MGI:MGI:3714574 NCBI chrNW_004936574:5,985,181...6,155,067 JBrowse link
G Lrg1 leucine rich alpha-2-glycoprotein 1 ISO (MGI:MGI:5543310|PMID:23868260) MGI PMID:23868260 MGI:MGI:5543310 NCBI chrNW_004936588:2,638,597...2,640,856 JBrowse link
G Men1 menin 1 ISO (PMID:11274402) UniProtKB PMID:11274402 NCBI chrNW_004936599:4,504,489...4,510,085 JBrowse link
G Myocd myocardin ISO (MGI:MGI:3696631|PMID:16224064) BHF-UCL PMID:16224064 MGI:MGI:3696631 NCBI chrNW_004936595:5,256,615...5,356,563 JBrowse link
G Npnt nephronectin ISO (MGI:MGI:3714574|PMID:17537792) MGI PMID:17537792 MGI:MGI:3714574 NCBI chrNW_004936814:1,096,604...1,165,755 JBrowse link
G Rnf111 ring finger protein 111 ISO (MGI:MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:MGI:3628833 NCBI chrNW_004936471:20,139,798...20,210,291 JBrowse link
G Sdcbp syndecan binding protein ISO (PMID:25893292) UniProtKB PMID:25893292 NCBI chrNW_004936496:14,331,971...14,347,123 JBrowse link
G Slc2a10 solute carrier family 2 member 10 ISO (PMID:26376865) ARUK-UCL PMID:26376865 NCBI chrNW_004936514:6,490,728...6,504,152 JBrowse link
G Smad4 SMAD family member 4 ISO (PMID:19328798) BHF-UCL PMID:19328798 NCBI chrNW_004936497:12,242,869...12,278,012 JBrowse link
G Snw1 SNW domain containing 1 ISO (PMID:11278756) UniProtKB PMID:11278756 NCBI chrNW_004936488:6,494,556...6,531,297 JBrowse link
G Stk11 serine/threonine kinase 11 ISO (MGI:MGI:3788958|PMID:18311138)
(PMID:18311138)
BHF-UCL PMID:18311138 MGI:MGI:3788958 NCBI chrNW_004936588:579,816...601,033 JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 ISO (PMID:18762808) BHF-UCL PMID:18762808 NCBI chrNW_004936543:8,347,343...8,352,909 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO (MGI:MGI:5617089|PMID:25382630) MGI
RGD
PMID:8106553, PMID:25382630 MGI:MGI:5617089, RGD:1579949 NCBI chrNW_004936537:7,154,125...7,340,218 JBrowse link
G Thbs1 thrombospondin 1 ISO (PMID:18555217)
(MGI:MGI:1270011|PMID:9657149)
BHF-UCL PMID:9657149, PMID:18555217 MGI:MGI:1270011 NCBI chrNW_004936471:3,064,466...3,081,125 JBrowse link
regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl9 BCL9 transcription coactivator NOT ISO (PMID:19328798) BHF-UCL PMID:19328798 NCBI chrNW_004936867:136,798...158,936 JBrowse link
G Cav3 caveolin 3 ISO (MGI:MGI:4946902|PMID:21182936) MGI PMID:21182936 MGI:MGI:4946902 NCBI chrNW_004936602:4,264,896...4,278,160 JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 ISO (MGI:MGI:1335654|PMID:10208746) MGI PMID:10208746 MGI:MGI:1335654 NCBI chrNW_004936659:2,022,657...2,025,353 JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 ISO (PMID:14612439) HGNC PMID:14612439 NCBI chrNW_004936661:2,364,179...2,366,739 JBrowse link
G Eng endoglin ISO (PMID:15702480) HGNC
RGD
PMID:15702480, PMID:17376778 RGD:2313627 NCBI chrNW_004936487:15,467,165...15,499,180 JBrowse link
G Folr1 folate receptor alpha ISO (MGI:MGI:5644149|PMID:21649587) BHF-UCL PMID:21649587 MGI:MGI:5644149 NCBI chrNW_004936498:1,489,916...1,497,200 JBrowse link
G Gdf2 growth differentiation factor 2 NOT ISO (MGI:MGI:4830635|PMID:20406889) DFLAT PMID:20406889 MGI:MGI:4830635 NCBI chrNW_004936554:7,307,461...7,322,048 JBrowse link
G Il17f interleukin 17F ISO (PMID:11591732) UniProtKB PMID:11591732 NCBI chrNW_004936476:8,579,282...8,580,916 JBrowse link
G Itga3 integrin subunit alpha 3 ISO (PMID:24621570) UniProtKB PMID:24621570 NCBI chrNW_004936490:11,553,904...11,583,387 JBrowse link
G Lox lysyl oxidase ISO (MGI:MGI:5634219|PMID:25715398) MGI PMID:25715398 MGI:MGI:5634219 NCBI chrNW_004936575:2,526,067...2,533,996 JBrowse link
G Nrep neuronal regeneration related protein ISO (MGI:MGI:3034115|PMID:14985127) MGI PMID:14985127 MGI:MGI:3034115 NCBI chrNW_004936531:6,077,691...6,105,517 JBrowse link
G Smad2 SMAD family member 2 ISO (PMID:14555988) BHF-UCL PMID:14555988 NCBI chrNW_004936497:14,723,199...14,812,160 JBrowse link
G Smad3 SMAD family member 3 ISO (MGI:MGI:2153314|PMID:11711431)
(PMID:8774881)
MGI
BHF-UCL
PMID:8774881, PMID:11711431 MGI:MGI:2153314 NCBI chrNW_004936471:27,080,662...27,185,861 JBrowse link
G Smad4 SMAD family member 4 ISO (PMID:8774881) BHF-UCL PMID:8774881 NCBI chrNW_004936497:12,242,869...12,278,012 JBrowse link
G Smad7 SMAD family member 7 ISO RGD PMID:11959632 RGD:625758 NCBI chrNW_004936497:13,894,586...13,921,978 JBrowse link
G Sox11 SRY-box transcription factor 11 ISO (PMID:20624318) UniProtKB PMID:20624318 NCBI chrNW_004937107:203,120...207,185 JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO (PMID:15334054) BHF-UCL PMID:15334054 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Trim33 tripartite motif containing 33 ISO (PMID:19135894) UniProtKB PMID:19135894 NCBI chrNW_004936690:2,709,059...2,898,399 JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 ISO (MGI:MGI:3641341|PMID:16824956) MGI PMID:16824956 MGI:MGI:3641341 NCBI chrNW_004936574:17,643...175,762 JBrowse link
G Znf703 zinc finger protein 703 ISO (MGI:MGI:4940410|PMID:21317240)
(PMID:21337521)
UniProtKB PMID:21317240, PMID:21337521 MGI:MGI:4940410 NCBI chrNW_004936710:1,155,007...1,158,972 JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbn1 fibrillin 1 ISO (MGI:MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:MGI:4836762 NCBI chrNW_004936471:10,747,030...10,969,223 JBrowse link
G Fbn2 fibrillin 2 ISO (MGI:MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:MGI:4836762 NCBI chrNW_004936504:1,535,629...1,757,386 JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 ISO (PMID:2022183), (PMID:8617200) UniProt PMID:2022183, PMID:8617200 NCBI chrNW_004936493:253,390...640,140 JBrowse link
G Nrros negative regulator of reactive oxygen species ISO (MGI:MGI:6192878|PMID:29909984) UniProt PMID:29909984 MGI:MGI:6192878 NCBI chrNW_004936784:1,222,381...1,250,501 JBrowse link
transforming growth factor beta receptor complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor type 1C ISO TbetaR-II, ActR-II (Chlorocebus aethiops), ligand-dependent RGD PMID:8940033 RGD:631880 NCBI chrNW_004936469:20,892,715...20,964,674 JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 ISO (PMID:14612439) HGNC PMID:14612439 NCBI chrNW_004936661:2,364,179...2,366,739 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO RGD PMID:8106553 RGD:1579949 NCBI chrNW_004936537:7,154,125...7,340,218 JBrowse link
transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 ISO PMID:12968668
(MGI:MGI:1935017|PMID:11376112)
(PMID:8242742)
UniProt
MGI
UniProtKB
PMID:8242742, PMID:11376112, PMID:12968668 MGI:MGI:1935017, RGD:8554636 NCBI chrNW_004936469:20,743,195...20,811,567 JBrowse link
G Acvrl1 activin A receptor like type 1 ISO (PMID:15702480)
(MGI:MGI:2679137|PMID:14580334)
HGNC
MGI
PMID:14580334, PMID:15702480 MGI:MGI:2679137 NCBI chrNW_004936512:9,364,551...9,379,131 JBrowse link
G Adam9 ADAM metallopeptidase domain 9 ISO (MGI:MGI:3828410|PMID:11955914)
(PMID:11955914)
BHF-UCL PMID:11955914 MGI:MGI:3828410 NCBI chrNW_004936710:2,301,470...2,388,533 JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 ISO PMID:11376112 MGI PMID:11376112 RGD:8554753 NCBI chrNW_004936512:10,706,043...10,712,797 JBrowse link
G Apoa1 apolipoprotein A1 NOT ISO (PMID:23726972) UniProtKB PMID:23726972 NCBI chrNW_004936542:2,111,055...2,112,626 JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 ISO (PMID:26583432) UniProt PMID:26583432 NCBI chrNW_004936473:7,580,495...7,647,471 JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 ISO (PMID:26583432) UniProt PMID:26583432 NCBI chrNW_004936492:9,477,483...9,526,692 JBrowse link
G Arrb2 arrestin beta 2 ISO (PMID:12958365) BHF-UCL PMID:12958365 NCBI chrNW_004936677:3,173,054...3,181,475 JBrowse link
G Bambi BMP and activin membrane bound inhibitor ISO RGD PMID:12933693 RGD:632261 NCBI chrNW_004936613:3,098,549...3,103,868 JBrowse link
G Cdh5 cadherin 5 ISO (PMID:21168935) UniProtKB PMID:21168935 NCBI chrNW_004936475:16,738,772...16,775,000 JBrowse link
G Cited1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 ISO (PMID:9707553) BHF-UCL PMID:9707553 NCBI chrNW_004936762:1,387,354...1,392,955 JBrowse link
G Cited2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO (MGI:MGI:3690196|PMID:16619037) MGI PMID:16619037 MGI:MGI:3690196 NCBI chrNW_004936560:6,353,901...6,356,749 JBrowse link
G Cldn5 claudin 5 ISO (PMID:21168935) UniProtKB PMID:21168935 NCBI chrNW_004936619:3,455,508...3,457,053 JBrowse link
G Col1a2 collagen type I alpha 2 chain ISO (PMID:17217948) UniProtKB PMID:17217948 NCBI chrNW_004936585:5,650,322...5,686,393 JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO (PMID:16360482) UniProtKB PMID:16360482 NCBI chrNW_004936506:8,886,494...8,923,921 JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO RGD PMID:16891311 RGD:1625706 NCBI chrNW_004936631:3,721,307...3,785,346 JBrowse link
G Dusp22 dual specificity phosphatase 22 ISO (MGI:MGI:2387732|PMID:12138158) MGI PMID:12138158 MGI:MGI:2387732 NCBI chrNW_004936633:1,459,487...1,528,080 JBrowse link
G Eng endoglin NOT ISO (PMID:12015308), (PMID:18223685)
(PMID:8294451)
(PMID:18223685)
BHF-UCL PMID:8294451, PMID:12015308, PMID:18223685 NCBI chrNW_004936487:15,467,165...15,499,180 JBrowse link
G Fermt2 fermitin family member 2 ISO (PMID:21325030) UniProtKB PMID:21325030 NCBI chrNW_004936697:1,927,817...2,008,268 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO (PMID:9732876) BHF-UCL PMID:9732876 NCBI chrNW_004936488:4,384,710...4,388,118 JBrowse link
G Foxh1 forkhead box H1 ISO (MGI:MGI:1321467|PMID:9858566)
(MGI:MGI:1328655|PMID:10349617), (MGI:MGI:3055632|PMID:15363409)
BHF-UCL PMID:9858566, PMID:10349617, PMID:15363409 MGI:MGI:1321467, MGI:MGI:1328655, MGI:MGI:3055632 NCBI chrNW_004936470:7,789,486...7,791,067 JBrowse link
G Fshb follicle stimulating hormone subunit beta ISO (PMID:14557487) BHF-UCL PMID:14557487 NCBI chrNW_004936533:7,395,206...7,397,266 JBrowse link
G Fut8 fucosyltransferase 8 ISO (MGI:MGI:3608245|PMID:16236725) MGI PMID:16236725 MGI:MGI:3608245 NCBI chrNW_004936495:9,012,425...9,341,538 JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 ISO (MGI:MGI:3696537|PMID:17159989) MGI PMID:17159989 MGI:MGI:3696537 NCBI chrNW_004936592:3,800,619...3,934,347 JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase ISO (PMID:15574495) UniProtKB PMID:15574495 NCBI chrNW_004936516:5,551,192...5,578,796 JBrowse link
G Itgb1 integrin subunit beta 1 NOT ISO (PMID:24036928)
(MGI:MGI:5582864|PMID:24036928)
UniProtKB PMID:24036928 MGI:MGI:5582864 NCBI chrNW_004936574:1,465,981...1,495,717 JBrowse link
G Itgb5 integrin subunit beta 5 ISO (MGI:MGI:5582864|PMID:24036928)
(PMID:24036928)
UniProtKB PMID:24036928 MGI:MGI:5582864 NCBI chrNW_004936725:417,824...530,993 JBrowse link
G Itgb6 integrin subunit beta 6 ISO (MGI:MGI:3040752|PMID:12634787)
(MGI:MGI:6376388|PMID:30952606)
MGI PMID:12634787, PMID:30952606 MGI:MGI:3040752, MGI:MGI:6376388 NCBI chrNW_004936469:18,581,855...18,650,109 JBrowse link
G Itgb8 integrin subunit beta 8 ISO (MGI:MGI:6376388|PMID:30952606) MGI PMID:30952606 MGI:MGI:6376388 NCBI chrNW_004936546:6,352,186...6,447,458 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO (PMID:9732876) BHF-UCL PMID:9732876 NCBI chrNW_004936522:3,034,364...3,037,632 JBrowse link
G LOC101978685 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase ISO (PMID:21750175)
(MGI:MGI:5545971|PMID:21750175)
UniProtKB PMID:21750175 MGI:MGI:5545971 NCBI chrNW_004936534:2,311,217...2,366,327 JBrowse link
G Lrrc32 leucine rich repeat containing 32 ISO (PMID:19750484) UniProt PMID:19750484 NCBI chrNW_004936498:5,305,680...5,315,580 JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 ISO (MGI:MGI:72661|PMID:7730318)
(MGI:MGI:2389565|PMID:12379497)
MGI PMID:7730318, PMID:12379497 MGI:MGI:2389565, MGI:MGI:72661 NCBI chrNW_004936599:3,902,903...3,918,471 JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 ISO (MGI:MGI:2386340|PMID:12208849) MGI PMID:12208849 MGI:MGI:2386340 NCBI chrNW_004936661:2,919,444...2,945,847 JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO (MGI:MGI:2674169|PMID:12941696) MGI PMID:12941696 MGI:MGI:2674169 NCBI chrNW_004936480:11,082,811...11,156,691 JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 ISO (MGI:MGI:3607216|PMID:16145668) MGI PMID:16145668 MGI:MGI:3607216 NCBI chrNW_004936510:1,772,971...1,836,075 JBrowse link
G Mstn myostatin ISO (MGI:MGI:2676508|PMID:12595574) MGI PMID:12595574 MGI:MGI:2676508 NCBI chrNW_004936506:7,988,879...7,996,260 JBrowse link
G Nlk nemo like kinase ISO (PMID:15004007) UniProtKB PMID:15004007 NCBI chrNW_004936538:4,321,018...4,466,175 JBrowse link
G Nrros negative regulator of reactive oxygen species ISO (MGI:MGI:6192878|PMID:29909984) UniProt PMID:29909984 MGI:MGI:6192878 NCBI chrNW_004936784:1,222,381...1,250,501 JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO PMID:22073128 BHF-UCL PMID:22073128 RGD:8554355 NCBI chrNW_004936526:3,102,468...3,147,601 JBrowse link
G Pias2 protein inhibitor of activated STAT 2 NOT ISO (PMID:16777850) UniProt PMID:16777850 NCBI chrNW_004936517:72,676...152,926 JBrowse link
G Pml PML nuclear body scaffold ISO (MGI:MGI:3054278|PMID:15356634) MGI PMID:15356634 MGI:MGI:3054278 NCBI chrNW_004936471:33,135,186...33,173,218 JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO (PMID:24036928) UniProtKB PMID:24036928 NCBI chrNW_004936470:10,379,855...10,578,531 JBrowse link
G Ptprk protein tyrosine phosphatase receptor type K ISO (PMID:15899872) UniProtKB PMID:15899872 NCBI chrNW_004936639:1,279,795...1,683,944 JBrowse link
G Pxn paxillin ISO (MGI:MGI:5582864|PMID:24036928)
(PMID:24036928)
UniProtKB PMID:24036928 MGI:MGI:5582864 NCBI chrNW_004936668:660,415...709,282 JBrowse link
G Sirt1 sirtuin 1 ISO (PMID:23960241) BHF-UCL PMID:23960241 NCBI chrNW_004936521:10,296,097...10,316,673 JBrowse link
G Skil SKI like proto-oncogene ISO (MGI:MGI:3797158|PMID:18212064) MGI PMID:18212064 MGI:MGI:3797158 NCBI chrNW_004936593:2,109,414...2,132,871 JBrowse link
G Smad2 SMAD family member 2 ISO (PMID:8980228)
(MGI:MGI:3797158|PMID:18212064)
PMID:22073128
(PMID:18548003), (PMID:8752209), (PMID:9389648), (PMID:9732876)
(MGI:MGI:2153598|PMID:11557747), (MGI:MGI:3032478|PMID:14749725)
BHF-UCL
MGI
PMID:8752209, PMID:8980228, PMID:9389648, PMID:9732876, PMID:11557747, PMID:14749725, PMID:18212064, PMID:18548003, PMID:22073128 MGI:MGI:2153598, MGI:MGI:3032478, MGI:MGI:3797158, RGD:8554355 NCBI chrNW_004936497:14,723,199...14,812,160 JBrowse link
G Smad3 SMAD family member 3 ISO (MGI:MGI:3505646|PMID:15239668), (MGI:MGI:3690196|PMID:16619037), (MGI:MGI:5300220|PMID:21937600)
PMID:22073128
(PMID:18548003), (PMID:21947082), (PMID:9732876)
TGFbeta-1 dependent, in pancreatic stellate cells
MGI
BHF-UCL
RGD
PMID:9732876, PMID:15239668, PMID:16371439, PMID:16619037, PMID:16891311, PMID:18548003, PMID:21937600, PMID:21947082, PMID:22073128 MGI:MGI:3505646, MGI:MGI:3690196, MGI:MGI:5300220, RGD:1625706, RGD:2300404, RGD:8554355 NCBI chrNW_004936471:27,080,662...27,185,861 JBrowse link
G Smad4 SMAD family member 4 ISO (PMID:25514493)
(MGI:MGI:3797158|PMID:18212064)
(MGI:MGI:3769957|PMID:16330325)
(PMID:9389648), (PMID:9732876)
UniProt
MGI
BHF-UCL
PMID:9389648, PMID:9732876, PMID:16330325, PMID:18212064, PMID:25514493 MGI:MGI:3769957, MGI:MGI:3797158 NCBI chrNW_004936497:12,242,869...12,278,012 JBrowse link
G Smad5 SMAD family member 5 ISO (MGI:MGI:1935017|PMID:11376112) MGI PMID:11376112 MGI:MGI:1935017 NCBI chrNW_004936597:3,225,374...3,264,604 JBrowse link
G Smad7 SMAD family member 7 ISO (MGI:MGI:2153598|PMID:11557747) MGI PMID:11557747 MGI:MGI:2153598 NCBI chrNW_004936497:13,894,586...13,921,978 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO (PMID:24036928) UniProtKB PMID:24036928 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
G Tab1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO (MGI:MGI:2447107|PMID:12464436) MGI PMID:12464436 MGI:MGI:2447107 NCBI chrNW_004936492:2,207,147...2,234,573 JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO (MGI:MGI:2386340|PMID:12208849), (MGI:MGI:5543310|PMID:23868260)
(PMID:11157754), (PMID:9389648)
MGI
BHF-UCL
PMID:9389648, PMID:11157754, PMID:12208849, PMID:23868260 MGI:MGI:2386340, MGI:MGI:5543310 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Tgfb2 transforming growth factor beta 2 ISO (PMID:11157754), (PMID:18358889) BHF-UCL PMID:11157754, PMID:18358889 NCBI chrNW_004936628:310,720...394,002 JBrowse link
G Tgfb3 transforming growth factor beta 3 ISO (PMID:11157754), (PMID:18718461) BHF-UCL PMID:11157754, PMID:18718461 NCBI chrNW_004936488:4,986,712...5,008,728 JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 ISO (PMID:11157754), (PMID:9389648)
(MGI:MGI:1933434|PMID:11285230)
(MGI:MGI:3820811|PMID:18718461)
(MGI:MGI:3703113|PMID:17078885)
(PMID:1333888)
(MGI:MGI:2679137|PMID:14580334), (MGI:MGI:3575204|PMID:15820682)
(MGI:MGI:5298182|PMID:21832243)
BHF-UCL
MGI
RGD
PMID:1333888, PMID:8272871, PMID:9389648, PMID:11157754, PMID:11285230, PMID:14580334, PMID:15820682, PMID:17078885, PMID:17505012, PMID:18684975, PMID:18718461, PMID:21832243 MGI:MGI:1933434, MGI:MGI:2679137, MGI:MGI:3575204, MGI:MGI:3703113, MGI:MGI:3820811, MGI:MGI:5298182, RGD:2302021, RGD:2302517, RGD:737663 NCBI chrNW_004936524:7,656,523...7,680,043 JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 ISO (PMID:18453574)
(MGI:MGI:4949016|PMID:21420963)
(PMID:11157754), (PMID:1333888)
BHF-UCL
MGI
RGD
PMID:1333888, PMID:11157754, PMID:18453574, PMID:18684975, PMID:21420963 MGI:MGI:4949016, RGD:2302517 NCBI chrNW_004936473:21,324,669...21,409,430 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO (PMID:12958365)
(MGI:MGI:2663364|PMID:12773577)
(PMID:11157754)
(MGI:MGI:3699491|PMID:17295310), (MGI:MGI:3807767|PMID:11546783)
BHF-UCL PMID:11157754, PMID:11546783, PMID:12773577, PMID:12958365, PMID:17295310 MGI:MGI:2663364, MGI:MGI:3699491, MGI:MGI:3807767 NCBI chrNW_004936537:7,154,125...7,340,218 JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:3797158|PMID:18212064) MGI PMID:18212064 MGI:MGI:3797158 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 ISO (PMID:17164348) BHF-UCL PMID:17164348 NCBI chrNW_004936626:1,901,686...1,946,554 JBrowse link
G Usp15 ubiquitin specific peptidase 15 ISO (PMID:22344298)
(PMID:21947082)
UniProtKB PMID:21947082, PMID:22344298 NCBI chrNW_004936545:978,318...1,094,729 JBrowse link
G Usp9x ubiquitin specific peptidase 9 X-linked ISO (PMID:19135894) UniProtKB PMID:19135894 NCBI chrNW_004936502:7,649,808...7,732,731 JBrowse link
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 ISO (MGI:MGI:2676508|PMID:12595574) MGI PMID:12595574 MGI:MGI:2676508 NCBI chrNW_004936490:10,897,390...10,903,605 JBrowse link
G Zfyve9 zinc finger FYVE-type containing 9 ISO (PMID:9865696) UniProtKB PMID:9865696 NCBI chrNW_004936522:8,632,626...8,808,008 JBrowse link
G Zmiz1 zinc finger MIZ-type containing 1 ISO (PMID:16777850) UniProt PMID:16777850 NCBI chrNW_004936521:444,599...664,533 JBrowse link
G Zmiz2 zinc finger MIZ-type containing 2 NOT ISO (PMID:16777850) UniProt PMID:16777850 NCBI chrNW_004936478:19,616,850...19,637,958 JBrowse link
G Zyx zyxin ISO (PMID:24036928)
(MGI:MGI:5582864|PMID:24036928)
UniProtKB PMID:24036928 MGI:MGI:5582864 NCBI chrNW_004936527:823,973...833,387 JBrowse link
transforming growth factor beta receptor signaling pathway involved in heart development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor beta 1 ISO (MGI:MGI:67103|PMID:8009224) BHF-UCL PMID:8009224 MGI:MGI:67103 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
transforming growth factor beta receptor signaling pathway involved in primitive streak formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor ISO (MGI:MGI:2677178|PMID:14511481) MGI PMID:14511481 MGI:MGI:2677178 NCBI chrNW_004936521:8,171,146...8,178,802 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    response to stimulus 6404
      response to endogenous stimulus 1690
        response to transforming growth factor beta 245
          cellular response to transforming growth factor beta stimulus + 236
Path 2
Term Annotations click to browse term
  biological_process 11962
    response to stimulus 6404
      response to chemical 3741
        response to organic substance 3010
          response to growth factor 718
            response to transforming growth factor beta 245
              cellular response to transforming growth factor beta stimulus + 236
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.