ONTOLOGY REPORT - ANNOTATIONS


Term:transforming growth factor beta production
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Accession:GO:0071604 term browser browse the term
Definition:The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.
Synonyms:exact_synonym: TGF-B production;   TGF-beta production;   TGFb production


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negative regulation of transforming growth factor beta activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr2b activin A receptor type 2B JBrowse link 8 128,087,308 128,126,776 RGD:1624291
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 JBrowse link 9 17,817,791 17,823,163 RGD:1624291
RGD:1600115
negative regulation of transforming growth factor beta production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:4145466
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:1624291
negative regulation of transforming growth factor beta1 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd2ap CD2-associated protein JBrowse link 9 20,794,680 20,858,438 RGD:1624291
RGD:1600115
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:1624291
RGD:1600115
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1600115
RGD:1624291
G Laptm4b lysosomal protein transmembrane 4 beta JBrowse link 7 72,924,911 72,968,099 RGD:1624291
RGD:1600115
G Tyrobp Tyro protein tyrosine kinase binding protein JBrowse link 1 88,875,370 88,879,305 RGD:1624291
negative regulation of transforming growth factor beta2 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdh3 cadherin 3 JBrowse link 19 38,668,957 38,719,801 RGD:1624291
RGD:1600115
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1600115
RGD:1624291
negative regulation of transforming growth factor beta3 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
RGD:8553566
RGD:1600115
positive regulation of transforming growth factor beta production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd200 Cd200 molecule JBrowse link 11 60,371,617 60,398,450 RGD:1600115
RGD:1624291
G Cd34 CD34 molecule JBrowse link 13 113,691,842 113,711,259 RGD:1624291
RGD:1600115
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:11532676
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:5135054
G Serpinf2 serpin family F member 2 JBrowse link 10 62,264,247 62,272,353 RGD:1624291
RGD:1600115
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:2317942
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
positive regulation of transforming growth factor beta1 activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:1600115
RGD:1624291
positive regulation of transforming growth factor beta1 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp6ap2 ATPase H+ transporting accessory protein 2 JBrowse link X 11,137,889 11,164,854 RGD:1624291
RGD:1600115
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:1624291
RGD:1600115
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
RGD:1600115
G Lum lumican JBrowse link 7 38,820,058 38,826,862 RGD:1624291
RGD:1600115
G Serpinb7 serpin family B member 7 JBrowse link 13 27,282,456 27,354,775 RGD:7207383
positive regulation of transforming growth factor beta2 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf2 activating transcription factor 2 JBrowse link 3 60,721,137 60,795,951 RGD:1624291
RGD:1600115
G Wnt11 Wnt family member 11 JBrowse link 1 163,794,136 163,813,756 RGD:1624291
RGD:1600115
positive regulation of transforming growth factor beta3 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:1625706
RGD:10059386
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:1625706
regulation of transforming growth factor beta activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Itgav integrin subunit alpha V JBrowse link 3 71,113,269 71,205,958 RGD:1600115
RGD:1624291
G Itgb6 integrin subunit beta 6 JBrowse link 3 46,652,624 46,775,362 RGD:1600115
RGD:1624291
G Itgb8 integrin subunit beta 8 JBrowse link 6 147,089,280 147,172,846 RGD:1600115
RGD:1624291
G Lrrc32 leucine rich repeat containing 32 JBrowse link 1 163,443,972 163,457,426 RGD:1624291
G Ltbp1 latent transforming growth factor beta binding protein 1 JBrowse link 6 21,203,502 21,600,441 RGD:1600115
RGD:1624291
regulation of transforming growth factor beta2 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:1624291
RGD:1600115
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
RGD:1600115
regulation of transforming growth factor beta3 activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrc32 leucine rich repeat containing 32 JBrowse link 1 163,443,972 163,457,426 RGD:1600115
RGD:1624291
transforming growth factor beta activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ltbp3 latent transforming growth factor beta binding protein 3 JBrowse link 1 221,099,155 221,116,096 RGD:1624291
RGD:1600115
transforming growth factor beta1 activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nrros negative regulator of reactive oxygen species JBrowse link 11 71,872,728 71,889,897 RGD:1600115
RGD:1624291

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.