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ONTOLOGY REPORT - ANNOTATIONS


Term:cytoplasm protein quality control by the ubiquitin-proteasome system
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Accession:GO:0071629 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation.
Comment:See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.
Synonyms:exact_synonym: cytoplasm-associated proteasomal ubiquitin-dependent protein breakdown;   cytoplasm-associated proteasomal ubiquitin-dependent protein catabolism;   cytoplasm-associated proteasomal ubiquitin-dependent protein degradation;   ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome


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cytoplasm protein quality control by the ubiquitin-proteasome system term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf126 ring finger protein 126 JBrowse link 7 12,820,796 12,828,325 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    cellular process 18362
      cellular response to stimulus 8794
        cellular response to stress 1978
          cellular response to topologically incorrect protein 117
            cellular response to misfolded protein 23
              cytoplasm protein quality control by the ubiquitin-proteasome system 1
Path 2
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      organic substance metabolic process 11299
        macromolecule metabolic process 9767
          macromolecule catabolic process 1309
            protein catabolic process 970
              cellular protein catabolic process 804
                proteolysis involved in cellular protein catabolic process 751
                  modification-dependent protein catabolic process 639
                    ubiquitin-dependent protein catabolic process 628
                      proteasome-mediated ubiquitin-dependent protein catabolic process 412
                        cytoplasm protein quality control by the ubiquitin-proteasome system 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.