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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of transforming growth factor beta production
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Accession:GO:0071635 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta.
Synonyms:exact_synonym: negative regulation of TGF-B production;   negative regulation of TGF-beta production;   negative regulation of TGFb production;   negative regulation of TGFbeta production
 narrow_synonym: negative regulation of transforming growth factor-beta secretion
 alt_id: GO:2001202


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negative regulation of transforming growth factor beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbln1 fibulin 1 ISO (PMID:25834989) RGD PMID:25834989 NCBI chr 7:126,096,793...126,176,468
Ensembl chr 7:126,096,793...126,176,468
JBrowse link
G Fn1 fibronectin 1 ISO (PMID:25834989) RGD PMID:25834989 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Il13 interleukin 13 IDA RGD PMID:20100461 RGD:4145466 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO MGI:MGI:3041135 (MGI:MGI:5529574|PMID:23994610) RGD PMID:23994610 MGI:MGI:5529574 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:29700287 RGD:26884455 NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911
JBrowse link
negative regulation of transforming growth factor beta activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B ISO RGD DOI:10.1016/j.procbio.2011.10.027 NCBI chr 8:128,087,308...128,126,776
Ensembl chr 8:128,087,345...128,118,746
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO
ISS
(PMID:20599762)
GO_REF:0000024
RGD
UniProt
PMID:20599762 GO_REF:0000024 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
negative regulation of transforming growth factor beta1 activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fkbp1a FKBP prolyl isomerase 1A ISO (PMID:11583628) RGD PMID:11583628 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
negative regulation of transforming growth factor beta1 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd2ap CD2-associated protein ISO MGI:MGI:98725 (MGI:MGI:5297732|PMID:21911934) RGD PMID:21911934 MGI:MGI:5297732 NCBI chr 9:20,794,680...20,858,438
Ensembl chr 9:20,765,296...20,858,504
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) ISO
IEA
(PMID:15899807)
GO_REF:0000107
RGD
Ensembl
PMID:15899807 GO_REF:0000107 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182
JBrowse link
G Gata6 GATA binding protein 6 IEA
ISO
GO_REF:0000107
(PMID:21127043)
Ensembl
RGD
PMID:21127043 GO_REF:0000107 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta ISO
ISS
(PMID:26126825)
GO_REF:0000024
RGD
UniProt
PMID:26126825 GO_REF:0000024 NCBI chr 7:72,924,911...72,968,099
Ensembl chr 7:72,924,799...72,968,101
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp ISO
IBA
(MGI:MGI:5638298|PMID:25690660)
PMID:21873635
RGD PMID:25690660, PMID:21873635 MGI:MGI:5638298, RGD:13792537 NCBI chr 1:88,875,370...88,879,305
Ensembl chr 1:88,875,375...88,879,303
JBrowse link
negative regulation of transforming growth factor beta2 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh3 cadherin 3 ISO (PMID:22696062) RGD PMID:22696062 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
JBrowse link
G Gata6 GATA binding protein 6 IEA
ISO
GO_REF:0000107
(PMID:21127043)
Ensembl
RGD
PMID:21127043 GO_REF:0000107 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
negative regulation of transforming growth factor beta3 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule ISO
ISS
(PMID:16930538)
GO_REF:0000024
RGD
UniProt
PMID:16930538, PMID:16930538 GO_REF:0000024, RGD:8553566 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    multicellular organismal process 9046
      cytokine production 764
        transforming growth factor beta production 44
          negative regulation of transforming growth factor beta production 15
            negative regulation of transforming growth factor beta activation + 3
            negative regulation of transforming growth factor beta1 production + 6
            negative regulation of transforming growth factor beta2 production + 2
            negative regulation of transforming growth factor beta3 production + 1
Path 2
Term Annotations click to browse term
  biological_process 20028
    biological regulation 13773
      regulation of biological process 13075
        negative regulation of biological process 5686
          negative regulation of metabolic process 3311
            negative regulation of macromolecule metabolic process 3047
              negative regulation of gene expression 2169
                negative regulation of cytokine production 283
                  negative regulation of transforming growth factor beta production 15
                    negative regulation of transforming growth factor beta activation + 3
                    negative regulation of transforming growth factor beta1 production + 6
                    negative regulation of transforming growth factor beta2 production + 2
                    negative regulation of transforming growth factor beta3 production + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.