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Term:transcriptional activation by promoter-enhancer looping
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Accession:GO:0071733 term browser browse the term
Definition:The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter.
Synonyms:related_synonym: long-range enhancer-promoter communication

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transcriptional activation by promoter-enhancer looping term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA1 GATA binding protein 1 ISS BHF-UCL GO_REF:0000024 NCBI chr  X:48,786,540...48,794,311
Ensembl chr  X:48,786,562...48,794,311
Ensembl chr  X:48,786,562...48,794,311
JBrowse link
G NIPBL NIPBL cohesin loading factor IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:36,876,769...37,066,413
Ensembl chr 5:36,876,769...37,066,413
JBrowse link
G RUVBL2 RuvB like AAA ATPase 2 IMP (PMID:23637611) UniProtKB PMID:23637611 NCBI chr19:48,993,448...49,015,995
Ensembl chr19:48,993,562...49,015,970
JBrowse link
G ZFPM1 zinc finger protein, FOG family member 1 ISS BHF-UCL GO_REF:0000024 NCBI chr16:88,451,782...88,537,031
Ensembl chr16:88,453,280...88,537,031
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 18650
    cellular process 17668
      cellular component organization or biogenesis 7122
        cellular component organization 6931
          chromatin organization 879
            gene looping 4
              transcriptional activation by promoter-enhancer looping 4
Path 2
Term Annotations click to browse term
  biological_process 18650
    metabolic process 12284
      cellular metabolic process 11267
        cellular aromatic compound metabolic process 6226
          nucleobase-containing compound metabolic process 5975
            nucleic acid metabolic process 5426
              RNA metabolic process 4898
                regulation of RNA metabolic process 3998
                  regulation of RNA biosynthetic process 3712
                    regulation of nucleic acid-templated transcription 3707
                      regulation of transcription, DNA-templated 3636
                        positive regulation of transcription, DNA-templated 1713
                          positive regulation of transcription by RNA polymerase II 1391
                            transcriptional activation by promoter-enhancer looping 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.