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ONTOLOGY REPORT - ANNOTATIONS


Term:transcriptional activation by promoter-enhancer looping
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Accession:GO:0071733 term browser browse the term
Definition:The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter.
Synonyms:related_synonym: long-range enhancer-promoter communication


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transcriptional activation by promoter-enhancer looping term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata1 GATA binding protein 1 ISO (MGI:MGI:5284796|PMID:15644435) BHF-UCL PMID:15644435 MGI:MGI:5284796 NCBI chrNW_004936721:742,862...750,843 JBrowse link
G Ruvbl2 RuvB like AAA ATPase 2 ISO (PMID:23637611) UniProtKB PMID:23637611 NCBI chrNW_004936664:2,995,212...3,010,563 JBrowse link
G Zfpm1 zinc finger protein, FOG family member 1 ISO (MGI:MGI:5284796|PMID:15644435) BHF-UCL PMID:15644435 MGI:MGI:5284796 NCBI chrNW_004936641:1,130,073...1,162,022 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    cellular process 11135
      cellular component organization or biogenesis 4887
        cellular component organization 4809
          chromatin organization 543
            gene looping 3
              transcriptional activation by promoter-enhancer looping 3
Path 2
Term Annotations click to browse term
  biological_process 11962
    metabolic process 7653
      cellular metabolic process 7051
        cellular aromatic compound metabolic process 3743
          nucleobase-containing compound metabolic process 3574
            nucleic acid metabolic process 3288
              RNA metabolic process 2915
                regulation of RNA metabolic process 2500
                  regulation of RNA biosynthetic process 2291
                    regulation of nucleic acid-templated transcription 2286
                      regulation of transcription, DNA-templated 2278
                        positive regulation of transcription, DNA-templated 1389
                          positive regulation of transcription by RNA polymerase II 1110
                            transcriptional activation by promoter-enhancer looping 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.