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ONTOLOGY REPORT - ANNOTATIONS


Term:Ragulator complex
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Accession:GO:0071986 term browser browse the term
Definition:A eukaryotically conserved protein complex; in humans, it is comprised of LAMTOR1, LAMTOR2, LAMTOR3, LAMTOR4, and LAMTOR5. The complex is anchored to lipid rafts in late endosome membranes via LAMTOR1, constitutes a guanine nucleotide exchange factor (GEF) for the Rag GTPases.
Synonyms:exact_synonym: MAPKSP1/ROBLD3/C11orf59 complex


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Ragulator complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 JBrowse link 1 166,991,474 166,997,045 RGD:1624291
RGD:13792537
RGD:1600115
G Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 JBrowse link 2 187,911,530 187,914,930 RGD:1624291
RGD:13792537
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 JBrowse link 2 243,160,821 243,173,057 RGD:1624291
RGD:13792537
RGD:1600115
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 JBrowse link 12 19,573,909 19,577,625 RGD:1624291
RGD:13792537
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 2 210,034,095 210,039,451 RGD:1624291
RGD:13792537
G LOC100361543 RhoA activator C11orf59-like JBrowse link X 37,261,428 37,262,470 RGD:1600115
RGD:13792537
G Slc38a9 solute carrier family 38, member 9 JBrowse link 2 44,512,556 44,592,793 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19843
    protein-containing complex 5779
      membrane protein complex 1210
        Ragulator complex 7
Path 2
Term Annotations click to browse term
  cellular_component 19843
    cellular anatomical entity 19457
      organelle 12557
        membrane-bounded organelle 10879
          vesicle 1980
            intracellular vesicle 1827
              cytoplasmic vesicle 1822
                endosome 822
                  endosome membrane 318
                    late endosome membrane 92
                      Ragulator complex 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.