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ONTOLOGY REPORT - ANNOTATIONS


Term:glomerular epithelium development
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Accession:GO:0072010 term browser browse the term
Definition:The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.


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glomerular epithelium development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc1 forkhead box C1 ISO (MGI:5883353|PMID:28223138) RGD PMID:28223138 MGI:5883353 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484
JBrowse link
glomerular endothelium development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 molecule ISO (PMID:17464107) RGD PMID:17464107 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
G Foxc2 forkhead box C2 ISO MGI:1857740 (MGI:3619287|PMID:16498405) RGD PMID:16498405 MGI:3619287 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO (PMID:17464107) RGD PMID:17464107 NCBI chr10:94,850,971...94,913,202 JBrowse link
glomerular parietal epithelial cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxj1 forkhead box J1 ISO (PMID:9530170) RGD PMID:9530170 NCBI chr10:105,282,090...105,289,396 JBrowse link
glomerular parietal epithelial cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule ISO
ISS
(PMID:19092120)
GO_REF:0000024
RGD
UniProt
PMID:19092120 GO_REF:0000024 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Prom1 prominin 1 ISO (PMID:19092120) RGD PMID:19092120 NCBI chr14:71,532,321...71,637,400
Ensembl chr14:71,533,063...71,637,417
JBrowse link
glomerular visceral epithelial cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ampd2 adenosine monophosphate deaminase 2 ISO MGI:3848348 (MGI:5647943|PMID:25361754) RGD PMID:25361754 MGI:5647943 NCBI chr 2:210,861,624...210,874,348
Ensembl chr 2:210,861,625...210,874,304
JBrowse link
G Asxl1 ASXL transcriptional regulator 1 ISO (MGI:5751943|PMID:26385183) RGD PMID:26385183 MGI:5751943 NCBI chr 3:148,832,231...148,902,356
Ensembl chr 3:148,837,814...148,900,452
JBrowse link
G Bmp4 bone morphogenetic protein 4 IEA
ISO
GO_REF:0000107
(PMID:17442697)
Ensembl
RGD
PMID:17442697 GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Jag1 jagged canonical Notch ligand 1 IEA
ISO
ISS
GO_REF:0000107
(MGI:5498584|PMID:23806616)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23806616 GO_REF:0000024, GO_REF:0000107, MGI:5498584 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 IEP PMID:15994232 UniProt PMID:15994232 RGD:8553727 NCBI chr 4:10,995,241...12,472,423
Ensembl chr 4:10,995,234...11,610,518
JBrowse link
G Myo1e myosin IE ISS
ISO
IEA
GO_REF:0000024
(MGI:4441423|PMID:19005011)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19005011 GO_REF:0000024, GO_REF:0000107, MGI:4441423 NCBI chr 8:76,644,715...76,840,240
Ensembl chr 8:76,754,492...76,839,593
JBrowse link
G Notch2 notch receptor 2 ISO
IEA
(PMID:15821257)
GO_REF:0000107
RGD
Ensembl
PMID:15821257 GO_REF:0000107 NCBI chr 2:200,187,184...200,320,403
Ensembl chr 2:200,187,179...200,320,215
JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:88,922,346...88,950,560
Ensembl chr 1:88,922,433...88,950,559
JBrowse link
G Podxl podocalyxin-like IEP PMID:15994232 UniProt PMID:15994232 RGD:8553727 NCBI chr 4:58,829,049...58,893,353
Ensembl chr 4:58,829,060...58,893,170
JBrowse link
G Wt1 WT1 transcription factor ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
glomerular visceral epithelial cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Basp1 brain abundant, membrane attached signal protein 1 IEA
ISO
GO_REF:0000107
(MGI:4418604|PMID:19050011)
Ensembl
RGD
PMID:19050011 GO_REF:0000107, MGI:4418604 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Cd24 CD24 molecule ISO
ISS
(PMID:19092120)
GO_REF:0000024
RGD
UniProt
PMID:19092120 GO_REF:0000024 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Ext1 exostosin glycosyltransferase 1 ISO (MGI:4360160|PMID:18480751) RGD PMID:18480751 MGI:4360160 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068
JBrowse link
G Foxc2 forkhead box C2 ISO MGI:1857740 (MGI:3619287|PMID:16498405) RGD PMID:16498405 MGI:3619287 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081
JBrowse link
G Klf15 Kruppel-like factor 15 ISO (MGI:5431194|PMID:22493483) RGD PMID:22493483 MGI:5431194 NCBI chr 4:122,364,688...122,377,690
Ensembl chr 4:122,365,093...122,377,659
JBrowse link
G Prom1 prominin 1 ISO (PMID:19092120) RGD PMID:19092120 NCBI chr14:71,532,321...71,637,400
Ensembl chr14:71,533,063...71,637,417
JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O ISS
ISO
IBA
GO_REF:0000024
(MGI:1927435|PMID:11086029)
PMID:21873635
UniProt
RGD
PMID:11086029, PMID:21873635 GO_REF:0000024, MGI:1927435, RGD:13792537 NCBI chr 4:171,250,766...171,461,571
Ensembl chr 4:171,250,818...171,461,677
JBrowse link
G Wt1 WT1 transcription factor ISS
ISO
GO_REF:0000024
(MGI:4418604|PMID:19050011)
UniProt
RGD
PMID:19050011 GO_REF:0000024, MGI:4418604 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B ISO (PMID:9693135) RGD PMID:9693135 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamb2 laminin subunit beta 2 IEA
ISO
GO_REF:0000107
MGI:2138070 (MGI:3664526|PMID:16886065)
Ensembl
RGD
PMID:16886065 GO_REF:0000107, MGI:3664526 NCBI chr 8:117,268,335...117,280,517
Ensembl chr 8:117,268,337...117,280,517
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin ISO (PMID:11786407) RGD PMID:11786407 NCBI chr13:73,929,136...73,941,522
Ensembl chr13:73,929,136...73,941,522
JBrowse link
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISS
ISO
GO_REF:0000024
(MGI:3795840|PMID:18431508)
UniProt
RGD
PMID:18431508 GO_REF:0000024, MGI:3795840 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        glomerulus development 73
          glomerular epithelium development 25
            glomerular endothelium development + 4
            glomerular epithelial cell differentiation + 21
            mesonephric glomerular epithelium development + 0
            metanephric glomerular epithelium development + 4
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            urogenital system development 432
              renal system development 382
                kidney development 368
                  nephron development 166
                    nephron epithelium development 124
                      glomerular epithelium development 25
                        glomerular endothelium development + 4
                        glomerular epithelial cell differentiation + 21
                        mesonephric glomerular epithelium development + 0
                        metanephric glomerular epithelium development + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.