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ONTOLOGY REPORT - ANNOTATIONS


Term:distal tubule development
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Accession:GO:0072017 term browser browse the term
Definition:The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.


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distal tubule development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jag1 jagged canonical Notch ligand 1 IEA
ISO
GO_REF:0000107
(PMID:15821257)
Ensembl
RGD
PMID:15821257 GO_REF:0000107 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Notch1 notch receptor 1 ISO (PMID:15821257) RGD PMID:15821257 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Tfap2b transcription factor AP-2 beta ISO
ISS
(MGI:MGI:2656435|PMID:12695560)
GO_REF:0000024
RGD
UniProt
PMID:12695560 GO_REF:0000024, MGI:MGI:2656435 NCBI chr 9:25,410,669...25,440,568
Ensembl chr 9:25,410,669...25,440,411
JBrowse link
distal tubule morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klhl3 kelch-like family member 3 ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:22406640), (PMID:23453970), (PMID:23576762)
UniProt
Ensembl
RGD
PMID:22406640, PMID:23453970, PMID:23576762 GO_REF:0000024, GO_REF:0000107 NCBI chr17:6,924,423...7,029,374
Ensembl chr17:6,935,860...7,029,240
JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 ISS
ISO
GO_REF:0000024
(PMID:23453970), (PMID:23576762)
UniProt
RGD
PMID:23453970, PMID:23576762 GO_REF:0000024 NCBI chr10:89,181,139...89,198,213
Ensembl chr10:89,181,165...89,198,213
JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 ISO
IEA
ISS
(MGI:MGI:2669573|PMID:12925600)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12925600 GO_REF:0000024, GO_REF:0000107, MGI:MGI:2669573 NCBI chr 9:49,479,148...49,482,246
Ensembl chr 9:49,479,023...49,482,252
JBrowse link
metanephric distal convoluted tubule development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 5:29,538,380...29,562,774
Ensembl chr 5:29,538,380...29,562,773
JBrowse link
G Pax2 paired box 2 ISO
ISS
(MGI:MGI:3704067|PMID:17314325)
GO_REF:0000024
RGD
UniProt
PMID:17314325 GO_REF:0000024, MGI:MGI:3704067 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 ISO
ISS
(MGI:MGI:3704067|PMID:17314325)
GO_REF:0000024
RGD
UniProt
PMID:17314325 GO_REF:0000024, MGI:MGI:3704067 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Umod uromodulin IEA
ISO
GO_REF:0000107
(PMID:18618131)
Ensembl
RGD
PMID:18618131 GO_REF:0000107 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376
JBrowse link
metanephric distal tubule development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd2 polycystin 2, transient receptor potential cation channel ISO (PMID:11891195) RGD PMID:11891195 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
metanephric distal tubule morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting ISO (PMID:11891195) RGD PMID:11891195 NCBI chr10:13,914,057...13,962,008
Ensembl chr10:13,915,214...13,962,008
JBrowse link
metanephric thick ascending limb development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 ISO
IEA
ISS
(MGI:MGI:2669573|PMID:12925600)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12925600 GO_REF:0000024, GO_REF:0000107, MGI:MGI:2669573 NCBI chr 9:49,479,148...49,482,246
Ensembl chr 9:49,479,023...49,482,252
JBrowse link
G Umod uromodulin IEA
ISO
GO_REF:0000107
(PMID:18618131)
Ensembl
RGD
PMID:18618131 GO_REF:0000107 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376
JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 ISO
ISS
(MGI:MGI:3704067|PMID:17314325)
GO_REF:0000024
RGD
UniProt
PMID:17314325 GO_REF:0000024, MGI:MGI:3704067 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 ISO
ISS
(MGI:MGI:3704067|PMID:17314325)
GO_REF:0000024
RGD
UniProt
PMID:17314325 GO_REF:0000024, MGI:MGI:3704067 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    developmental process 6827
      anatomical structure development 6269
        nephron development 166
          nephron epithelium development 124
            nephron tubule development 105
              distal tubule development 12
                distal convoluted tubule development + 5
                distal tubule morphogenesis + 3
                mesonephric distal tubule development + 0
                metanephric distal tubule development + 7
                pronephric distal tubule development + 0
                thick ascending limb development + 2
Path 2
Term Annotations click to browse term
  biological_process 20028
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            urogenital system development 432
              renal system development 382
                kidney development 368
                  nephron development 166
                    nephron epithelium development 124
                      nephron tubule development 105
                        distal tubule development 12
                          distal convoluted tubule development + 5
                          distal tubule morphogenesis + 3
                          mesonephric distal tubule development + 0
                          metanephric distal tubule development + 7
                          pronephric distal tubule development + 0
                          thick ascending limb development + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.