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ONTOLOGY REPORT - ANNOTATIONS


Term:S-shaped body morphogenesis
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Accession:GO:0072050 term browser browse the term
Definition:The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.


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S-shaped body morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dspp dentin sialophosphoprotein ISO (MGI:MGI:3686561|PMID:16937369) MGI PMID:16937369 MGI:MGI:3686561 NCBI chrNW_004936905:458,062...463,359 JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO (PMID:15821257) UniProtKB PMID:15821257 NCBI chrNW_004936711:640,002...642,580 JBrowse link
G Hes5 hes family bHLH transcription factor 5 ISO (PMID:15821257) UniProtKB PMID:15821257 NCBI chrNW_004936737:1,045,496...1,047,865 JBrowse link
G Hey1 hes related family bHLH transcription factor with YRPW motif 1 ISO (PMID:15821257) UniProtKB PMID:15821257 NCBI chrNW_004936871:666,961...670,910 JBrowse link
G Lhx1 LIM homeobox 1 ISO (MGI:MGI:5009392|PMID:17610272) UniProtKB PMID:17610272 MGI:MGI:5009392 NCBI chrNW_004936490:1,324,378...1,332,177 JBrowse link
G Pax8 paired box 8 ISO (PMID:1723950) UniProtKB PMID:1723950 NCBI chrNW_004936783:1,523,658...1,553,464 JBrowse link
metanephric S-shaped body morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhx1 LIM homeobox 1 ISO PMID:9496787
(PMID:7909549)
UniProt
UniProtKB
PMID:7909549, PMID:9496787 RGD:8553921 NCBI chrNW_004936490:1,324,378...1,332,177 JBrowse link
G Pax8 paired box 8 ISO (PMID:1337742) UniProtKB PMID:1337742 NCBI chrNW_004936783:1,523,658...1,553,464 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO PMID:10734101 UniProt PMID:10734101 RGD:8554631 NCBI chrNW_004936504:4,762,251...4,799,789 JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO (PMID:11891195) UniProtKB PMID:11891195 NCBI chrNW_004936905:76,781...128,995 JBrowse link
G Wt1 WT1 transcription factor ISO (PMID:18618131)
(PMID:10101119)
(MGI:MGI:1333093|PMID:10101119)
UniProtKB PMID:10101119, PMID:18618131 MGI:MGI:1333093 NCBI chrNW_004936533:5,411,949...5,459,693 JBrowse link
negative regulation of metanephric S-shaped body morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO (PMID:12141440) UniProtKB PMID:12141440 NCBI chrNW_004936697:1,054,237...1,061,468 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11966
    developmental process 5627
      anatomical structure morphogenesis 2513
        S-shaped body morphogenesis 10
          mesonephric S-shaped body morphogenesis 0
          metanephric S-shaped body morphogenesis + 6
Path 2
Term Annotations click to browse term
  biological_process 11966
    developmental process 5627
      anatomical structure development 5266
        multicellular organism development 4832
          system development 4554
            urogenital system development 403
              renal system development 358
                kidney development 344
                  kidney morphogenesis 104
                    nephron morphogenesis 86
                      S-shaped body morphogenesis 10
                        mesonephric S-shaped body morphogenesis 0
                        metanephric S-shaped body morphogenesis + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.