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ONTOLOGY REPORT - ANNOTATIONS


Term:loop of Henle development
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Accession:GO:0072070 term browser browse the term
Definition:The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule.
Synonyms:exact_synonym: intermediate tubule development
 alt_id: GO:0072018


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loop of Henle development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 IEA
ISO
GO_REF:0000107
(PMID:15821257)
Ensembl
RGD
PMID:15821257 GO_REF:0000107 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Jag1 jagged canonical Notch ligand 1 IEA
ISO
GO_REF:0000107
(PMID:15821257)
Ensembl
RGD
PMID:15821257 GO_REF:0000107 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Umod uromodulin ISO (MGI:MGI:3531218|PMID:15522986) RGD PMID:15522986 MGI:MGI:3531218 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376
JBrowse link
metanephric ascending thin limb development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting ISO (PMID:11891195) RGD PMID:11891195 NCBI chr10:13,914,057...13,962,008
Ensembl chr10:13,915,214...13,962,008
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO (PMID:11891195) RGD PMID:11891195 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
G Pou3f3 POU class 3 homeobox 3 ISO
IEA
ISS
(MGI:MGI:2669573|PMID:12925600)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12925600 GO_REF:0000024, GO_REF:0000107, MGI:MGI:2669573 NCBI chr 9:49,479,148...49,482,246
Ensembl chr 9:49,479,023...49,482,252
JBrowse link
G Umod uromodulin IEA
ISO
GO_REF:0000107
(PMID:18618131)
Ensembl
RGD
PMID:18618131 GO_REF:0000107 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376
JBrowse link
metanephric descending thin limb development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
metanephric loop of Henle development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 ISO
ISS
(MGI:MGI:2669573|PMID:12925600)
GO_REF:0000024
RGD
UniProt
PMID:12925600 GO_REF:0000024, MGI:MGI:2669573 NCBI chr 9:49,479,148...49,482,246
Ensembl chr 9:49,479,023...49,482,252
JBrowse link
G Wnt7b Wnt family member 7B ISO MGI:MGI:3793280 (MGI:MGI:3821953|PMID:19060336) RGD PMID:19060336 MGI:MGI:3821953 NCBI chr 7:126,423,418...126,465,724
Ensembl chr 7:126,420,656...126,465,723
JBrowse link
specification of loop of Henle identity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes5 hes family bHLH transcription factor 5 ISO (PMID:15821257) RGD PMID:15821257 NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
JBrowse link
G Irx1 iroquois homeobox 1 ISO (PMID:17875669) RGD PMID:17875669 NCBI chr 1:33,910,912...33,916,741
Ensembl chr 1:33,910,912...33,916,741
JBrowse link
G Irx2 iroquois homeobox 2 ISO (PMID:17875669) RGD PMID:17875669 NCBI chr 1:33,270,388...33,275,868
Ensembl chr 1:33,271,977...33,275,540
JBrowse link
G Irx3 iroquois homeobox 3 ISO (PMID:17875669) RGD PMID:17875669 NCBI chr19:15,838,714...15,842,135
Ensembl chr19:15,838,714...15,840,990
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        nephron development 166
          nephron epithelium development 124
            nephron tubule development 105
              loop of Henle development 12
                ascending thin limb development + 4
                descending thin limb development + 1
                metanephric loop of Henle development + 6
                specification of loop of Henle identity + 4
Path 2
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            urogenital system development 433
              renal system development 383
                kidney development 369
                  nephron development 166
                    nephron epithelium development 124
                      nephron tubule development 105
                        loop of Henle development 12
                          ascending thin limb development + 4
                          descending thin limb development + 1
                          metanephric loop of Henle development + 6
                          specification of loop of Henle identity + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.