ONTOLOGY REPORT - ANNOTATIONS


Term:stem cell proliferation
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Accession:GO:0072089 term browser browse the term
Definition:The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.


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stem cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A JBrowse link 5 8,567,091 8,748,570 RGD:2290270
G L3mbtl2 L3MBTL2 polycomb repressive complex 1 subunit JBrowse link 15 81,663,889 81,688,315 RGD:2290270
G Rnf43 ring finger protein 43 JBrowse link 11 87,663,087 87,735,539 RGD:2290270
G Trim71 tripartite motif-containing 71 JBrowse link 9 114,511,268 114,564,369 RGD:2290270
G Wnt3 wingless-type MMTV integration site family, member 3 JBrowse link 11 103,774,175 103,818,021 RGD:2290270
G Znrf3 zinc and ring finger 3 JBrowse link 11 5,276,329 5,444,847 RGD:2290270
asymmetric neuroblast division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef2 rho/rac guanine nucleotide exchange factor (GEF) 2 JBrowse link 3 88,593,115 88,649,532 RGD:2290270
G Sox5 SRY (sex determining region Y)-box 5 JBrowse link 6 143,828,425 144,781,989 RGD:2290270
G Tead3 TEA domain family member 3 JBrowse link 17 28,331,671 28,350,805 RGD:2290270
canonical Wnt signaling pathway involved in stem cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt3 wingless-type MMTV integration site family, member 3 JBrowse link 11 103,774,175 103,818,021 RGD:2290270
establishment of neuroblast polarity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dock7 dedicator of cytokinesis 7 JBrowse link 4 98,936,659 99,121,787 RGD:2290270
G Fgf13 fibroblast growth factor 13 JBrowse link X 59,062,139 59,585,572 RGD:2290270
G Rab10 RAB10, member RAS oncogene family JBrowse link 12 3,247,428 3,309,969 RGD:2290270
forebrain neuroblast division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aspm abnormal spindle microtubule assembly JBrowse link 1 139,454,033 139,494,088 RGD:2290270
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 3 131,110,263 131,224,357 RGD:2290270
hematopoietic stem cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 JBrowse link 9 108,602,942 108,649,530 RGD:2290270
G Babam1 BRISC and BRCA1 A complex member 1 JBrowse link 8 71,396,420 71,404,772 RGD:2290270
G Cd34 CD34 antigen JBrowse link 1 194,938,821 194,961,292 RGD:2290270
G Ctc1 CTS telomere maintenance complex component 1 JBrowse link 11 69,015,908 69,036,473 RGD:2290270
G Etv6 ets variant 6 JBrowse link 6 134,035,700 134,270,158 RGD:2290270
G Fubp1 far upstream element (FUSE) binding protein 1 JBrowse link 3 152,210,427 152,236,830 RGD:2290270
G Mecom MDS1 and EVI1 complex locus JBrowse link 3 29,951,296 30,509,783 RGD:2290270
G Nkap NFKB activating protein JBrowse link X 37,126,763 37,150,746 RGD:2290270
G Prg4 proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein) JBrowse link 1 150,449,412 150,466,221 RGD:2290270
G Sart3 squamous cell carcinoma antigen recognized by T cells 3 JBrowse link 5 113,742,444 113,772,505 RGD:2290270
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 3 83,766,158 83,774,314 RGD:2290270
G Shb src homology 2 domain-containing transforming protein B JBrowse link 4 45,423,276 45,530,828 RGD:2290270
G Wnt1 wingless-type MMTV integration site family, member 1 JBrowse link 15 98,789,857 98,793,830 RGD:2290270
G Wnt10b wingless-type MMTV integration site family, member 10B JBrowse link 15 98,770,712 98,778,212 RGD:2290270
G Wnt2b wingless-type MMTV integration site family, member 2B JBrowse link 3 104,944,805 104,961,709 RGD:2290270
G Wnt5a wingless-type MMTV integration site family, member 5A JBrowse link 14 28,505,473 28,527,448 RGD:2290270
mesenchymal stem cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Six2 sine oculis-related homeobox 2 JBrowse link 17 85,662,742 85,688,254 RGD:2290270
negative regulation of neuroblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdnf brain derived neurotrophic factor JBrowse link 2 109,674,700 109,727,043 RGD:2290270
G Cd24a CD24a antigen JBrowse link 10 43,579,169 43,584,265 RGD:2290270
G Ctnna1 catenin (cadherin associated protein), alpha 1 JBrowse link 18 35,118,912 35,254,775 RGD:2290270
G Kctd11 potassium channel tetramerisation domain containing 11 JBrowse link 11 69,878,264 69,880,985 RGD:2290270
G Nf1 neurofibromin 1 JBrowse link 11 79,338,389 79,581,609 RGD:2290270
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:2290270
G Trp53 transformation related protein 53 JBrowse link 11 69,580,359 69,591,873 RGD:2290270
G Vax1 ventral anterior homeobox 1 JBrowse link 19 59,164,480 59,170,029 RGD:2290270
negative regulation of stem cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbln1 fibulin 1 JBrowse link 15 85,205,942 85,286,294 RGD:2290270
G Fermt1 fermitin family member 1 JBrowse link 2 132,904,177 132,946,187 RGD:2290270
G Kdf1 keratinocyte differentiation factor 1 JBrowse link 4 133,518,923 133,530,790 RGD:2290270
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 JBrowse link 18 80,606,205 80,713,071 RGD:2290270
G Ovol1 ovo like zinc finger 1 JBrowse link 19 5,549,137 5,560,575 RGD:2290270
G Ovol2 ovo like zinc finger 2 JBrowse link 2 144,305,175 144,332,080 RGD:2290270
G Snai2 snail family zinc finger 2 JBrowse link 16 14,705,859 14,709,385 RGD:2290270
neuroblast division in subventricular zone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Numb NUMB endocytic adaptor protein JBrowse link 12 83,794,034 83,921,934 RGD:2290270
G Numbl numb-like JBrowse link 7 27,258,438 27,282,150 RGD:2290270
neuroblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acsl6 acyl-CoA synthetase long-chain family member 6 JBrowse link 11 54,303,824 54,364,756 RGD:2290270
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 10 87,491,041 87,493,660 RGD:2290270
G Dagla diacylglycerol lipase, alpha JBrowse link 19 10,245,265 10,304,877 RGD:2290270
G Daglb diacylglycerol lipase, beta JBrowse link 5 143,464,487 143,504,442 RGD:2290270
G Eml1 echinoderm microtubule associated protein like 1 JBrowse link 12 108,371,002 108,539,576 RGD:2290270
G Frs2 fibroblast growth factor receptor substrate 2 JBrowse link 10 117,070,127 117,148,474 RGD:2290270
G Fzd9 frizzled class receptor 9 JBrowse link 5 135,248,938 135,251,047 RGD:2290270
G Gh growth hormone JBrowse link 11 106,300,261 106,303,703 RGD:2290270
G Hhip Hedgehog-interacting protein JBrowse link 8 79,965,850 80,058,069 RGD:2290270
G Id4 inhibitor of DNA binding 4 JBrowse link 13 48,261,427 48,264,036 RGD:2290270
G Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 JBrowse link 6 126,636,463 126,645,801 RGD:2290270
G Nde1 nudE neurodevelopment protein 1 JBrowse link 16 14,163,275 14,192,928 RGD:2290270
G Neurod4 neurogenic differentiation 4 JBrowse link 10 130,268,152 130,280,240 RGD:2290270
G Numb NUMB endocytic adaptor protein JBrowse link 12 83,794,034 83,921,934 RGD:2290270
G Numbl numb-like JBrowse link 7 27,258,438 27,282,150 RGD:2290270
G Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 JBrowse link 11 74,673,949 74,724,384 RGD:2290270
G Plxnb2 plexin B2 JBrowse link 15 89,155,546 89,181,022 RGD:2290270
G Racgap1 Rac GTPase-activating protein 1 JBrowse link 15 99,620,496 99,651,656 RGD:2290270
G Shh sonic hedgehog JBrowse link 5 28,456,840 28,467,101 RGD:2290270
positive regulation of hematopoietic stem cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atxn1l ataxin 1-like JBrowse link 8 109,726,451 109,737,795 RGD:2290270
G Cxcl1 chemokine (C-X-C motif) ligand 1 JBrowse link 5 90,891,245 90,893,121 RGD:2290270
G Kitl kit ligand JBrowse link 10 100,015,635 100,100,416 RGD:2290270
G N4bp2l2 NEDD4 binding protein 2-like 2 JBrowse link 5 150,599,931 150,665,612 RGD:2290270
G Pdcd2 programmed cell death 2 JBrowse link 17 15,521,575 15,527,301 RGD:2290270
G Thpo thrombopoietin JBrowse link 16 20,724,454 20,734,511 RGD:2290270
positive regulation of mesenchymal stem cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 14 46,383,525 46,390,669 RGD:2290270
G Ltbp3 latent transforming growth factor beta binding protein 3 JBrowse link 19 5,740,904 5,758,532 RGD:2290270
positive regulation of neuroblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aspm abnormal spindle microtubule assembly JBrowse link 1 139,454,033 139,494,088 RGD:2290270
G Bex1 brain expressed X-linked 1 JBrowse link X 136,213,972 136,215,513 RGD:2290270
G Ctnnb1 catenin (cadherin associated protein), beta 1 JBrowse link 9 120,933,400 120,960,507 RGD:2290270
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 JBrowse link 8 94,772,180 94,782,427 RGD:2290270
G Cx3cr1 chemokine (C-X3-C motif) receptor 1 JBrowse link 9 120,048,683 120,068,296 RGD:2290270
G Dct dopachrome tautomerase JBrowse link 14 118,012,790 118,052,246 RGD:2290270
G Disc1 disrupted in schizophrenia 1 JBrowse link 8 125,050,766 125,265,143 RGD:2290270
G Dmrta2 doublesex and mab-3 related transcription factor like family A2 JBrowse link 4 109,977,782 109,983,699 RGD:2290270
G Drd2 dopamine receptor D2 JBrowse link 9 49,340,428 49,408,177 RGD:2290270
G Foxg1 forkhead box G1 JBrowse link 12 49,382,883 49,386,867 RGD:2290270
G Fzd3 frizzled class receptor 3 JBrowse link 14 65,192,441 65,262,463 RGD:2290270
G Gli3 GLI-Kruppel family member GLI3 JBrowse link 13 15,463,723 15,730,026 RGD:2290270
G Hif1a hypoxia inducible factor 1, alpha subunit JBrowse link 12 73,901,324 73,947,554 RGD:2290270
G Kdm1a lysine (K)-specific demethylase 1A JBrowse link 4 136,550,533 136,602,790 RGD:2290270
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 14 33,377,898 33,447,212 RGD:2290270
G Notch1 notch 1 JBrowse link 2 26,457,902 26,503,822 RGD:2290270
G Otp orthopedia homeobox JBrowse link 13 94,875,627 94,885,125 RGD:2290270
G Pax6 paired box 6 JBrowse link 2 105,668,896 105,698,410 RGD:2290270
G Prl2c2 prolactin family 2, subfamily c, member 2 JBrowse link 13 12,996,120 13,005,330 RGD:2290270
G Shh sonic hedgehog JBrowse link 5 28,456,840 28,467,101 RGD:2290270
G Smarcd3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 JBrowse link 5 24,592,622 24,624,456 RGD:2290270
G Smo smoothened, frizzled class receptor JBrowse link 6 29,735,497 29,761,366 RGD:2290270
G Sox10 SRY (sex determining region Y)-box 10 JBrowse link 15 79,154,913 79,164,490 RGD:2290270
G Sox2 SRY (sex determining region Y)-box 2 JBrowse link 3 34,649,995 34,652,461 RGD:2290270
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:2290270
G Vegfc vascular endothelial growth factor C JBrowse link 8 54,077,532 54,186,454 RGD:2290270
G Zfp335 zinc finger protein 335 JBrowse link 2 164,891,892 164,911,750 RGD:2290270
positive regulation of stem cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dppa2 developmental pluripotency associated 2 JBrowse link 16 48,310,274 48,319,513 RGD:2290270
G Epcam epithelial cell adhesion molecule JBrowse link 17 87,635,979 87,651,127 RGD:2290270
G Hdac5 histone deacetylase 5 JBrowse link 11 102,194,428 102,230,183 RGD:2290270
G Hmga2 high mobility group AT-hook 2 JBrowse link 10 120,361,268 120,476,935 RGD:2290270
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 1 178,321,108 178,337,810 RGD:2290270
G Kdm1a lysine (K)-specific demethylase 1A JBrowse link 4 136,550,533 136,602,790 RGD:2290270
G Mir205 microRNA 205 JBrowse link 1 193,507,463 193,507,530 RGD:2290270
G Mir320 microRNA 320 JBrowse link 14 70,443,510 70,443,591 RGD:2290270
G Mir702 microRNA 702 JBrowse link 5 136,991,433 136,991,541 RGD:2290270
G Nanog Nanog homeobox JBrowse link 6 122,706,483 122,714,633 RGD:2290270
G Nfya nuclear transcription factor-Y alpha JBrowse link 17 48,386,885 48,409,901 RGD:2290270
G Ngf nerve growth factor JBrowse link 3 102,469,919 102,521,013 RGD:2290270
G Nr2e1 nuclear receptor subfamily 2, group E, member 1 JBrowse link 10 42,561,963 42,583,588 RGD:2290270
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 1 138,062,859 138,175,756 RGD:2290270
G Setd1a SET domain containing 1A JBrowse link 7 127,776,104 127,800,122 RGD:2290270
G Sirt6 sirtuin 6 JBrowse link 10 81,621,786 81,627,797 RGD:2290270
G Sox11 SRY (sex determining region Y)-box 11 JBrowse link 12 27,334,268 27,342,718 RGD:2290270
G Taf4b TATA-box binding protein associated factor 4b JBrowse link 18 14,783,201 14,960,424 RGD:2290270
G Tbx3 T-box 3 JBrowse link 5 119,670,319 119,684,724 RGD:2290270
G Tert telomerase reverse transcriptase JBrowse link 13 73,626,179 73,652,366 RGD:2290270
regulation of hematopoietic stem cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 JBrowse link 11 105,967,945 105,989,964 RGD:2290270
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 JBrowse link 17 78,852,550 78,882,572 RGD:2290270
G Pim1 proviral integration site 1 JBrowse link 17 29,491,045 29,495,465 RGD:2290270
regulation of neuroblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 15 91,672,809 91,816,124 RGD:2290270
G Six3 sine oculis-related homeobox 3 JBrowse link 17 85,613,608 85,626,191 RGD:2290270
G Tafa1 TAFA chemokine like family member 1 JBrowse link 6 96,113,154 96,657,208 RGD:2290270
regulation of stem cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago3 argonaute RISC catalytic subunit 3 JBrowse link 4 126,326,989 126,429,674 RGD:2290270
G Dgcr8 DGCR8, microprocessor complex subunit JBrowse link 16 18,253,948 18,289,255 RGD:2290270
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link 8 25,513,623 25,575,718 RGD:2290270
G Hmgb2 high mobility group box 2 JBrowse link 8 57,511,843 57,515,999 RGD:2290270
G Mpl myeloproliferative leukemia virus oncogene JBrowse link 4 118,442,412 118,457,513 RGD:2290270
G Ncoa3 nuclear receptor coactivator 3 JBrowse link 2 165,992,636 166,073,242 RGD:2290270
G Nf2 neurofibromin 2 JBrowse link 11 4,757,644 4,849,544 RGD:2290270
G Sox17 SRY (sex determining region Y)-box 17 JBrowse link 1 4,490,928 4,497,386 RGD:2290270
G Sox18 SRY (sex determining region Y)-box 18 JBrowse link 2 181,669,837 181,671,640 RGD:2290270
G Yap1 yes-associated protein 1 JBrowse link 9 7,931,999 8,004,596 RGD:2290270
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 12 80,107,760 80,113,013 RGD:2290270
ventricular zone neuroblast division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dct dopachrome tautomerase JBrowse link 14 118,012,790 118,052,246 RGD:2290270
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link 8 25,513,623 25,575,718 RGD:2290270
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 7 130,162,451 130,266,944 RGD:2290270
Wnt signaling pathway involved in forebrain neuroblast division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 low density lipoprotein receptor-related protein 6 JBrowse link 6 134,446,476 134,567,018 RGD:2290270
G Wnt3a wingless-type MMTV integration site family, member 3A JBrowse link 11 59,248,036 59,290,751 RGD:2290270

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.