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ONTOLOGY REPORT - ANNOTATIONS


Term:glomerular mesangium development
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Accession:GO:0072109 term browser browse the term
Definition:The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus.


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glomerular mesangial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle ISO
IEA
(PMID:17464107)
GO_REF:0000107
RGD
Ensembl
PMID:17464107 GO_REF:0000107 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Foxc2 forkhead box C2 ISO MGI:1857740 (MGI:3619287|PMID:16498405) RGD PMID:16498405 MGI:3619287 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081
JBrowse link
G Gpr4 G protein-coupled receptor 4 ISO MGI:3700206 (MGI:3699048|PMID:17145776) RGD PMID:17145776 MGI:3699048 NCBI chr 1:80,125,639...80,136,786
Ensembl chr 1:80,135,391...80,136,880
JBrowse link
G Notch1 notch receptor 1 ISO (PMID:15821257) RGD PMID:15821257 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 IMP PMID:18723570 UniProt PMID:18723570 RGD:8553351 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
metanephric glomerular mesangial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B ISS
ISO
GO_REF:0000024
(MGI:3039044|PMID:15084468)
UniProt
RGD
PMID:15084468 GO_REF:0000024, MGI:3039044 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 molecule ISO (PMID:1868864) RGD PMID:1868864 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B ISO (MGI:1289803|PMID:9693135) RGD PMID:9693135 MGI:1289803 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISS
ISO
GO_REF:0000024
(MGI:1289803|PMID:9693135)
UniProt
RGD
PMID:9693135 GO_REF:0000024, MGI:1289803 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
metanephric glomerular mesangium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfrb platelet derived growth factor receptor beta ISO (PMID:9693135) RGD PMID:9693135 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:17244894)
Ensembl
UniProt
RGD
PMID:17244894 GO_REF:0000024, GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO (PMID:17244894) RGD PMID:17244894 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Ifng interferon gamma IMP RGD PMID:1906384 RGD:10755757 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wt1 WT1 transcription factor ISS
ISO
GO_REF:0000024
(MGI:1332959|PMID:10077614)
UniProt
RGD
PMID:10077614 GO_REF:0000024, MGI:1332959 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
positive regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3ar1 complement C3a receptor 1 IMP RGD PMID:23713944 RGD:7411623 NCBI chr 4:155,681,767...155,691,240
Ensembl chr 4:155,684,029...155,690,869
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IMP RGD PMID:24691542 RGD:11341715 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Il6r interleukin 6 receptor ISO (PMID:26563755) RGD PMID:26563755 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:20135641 RGD:4892623 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEA
ISO
ISS
GO_REF:0000107
(PMID:11788434), (PMID:16014047)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:11788434, PMID:16014047 GO_REF:0000024, GO_REF:0000107 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfd platelet derived growth factor D IMP RGD PMID:12937299 RGD:9854637 NCBI chr 8:4,441,010...4,666,754
Ensembl chr 8:4,440,876...4,669,014
JBrowse link
G Serpinb7 serpin family B member 7 IMP RGD PMID:21945418 RGD:7207383 NCBI chr13:27,282,456...27,354,775
Ensembl chr13:27,312,498...27,354,052
JBrowse link
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 IMP PMID:8910451 UniProt PMID:8910451 RGD:8553929 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A NOT ISO
ISS
(PMID:11788434)
GO_REF:0000024
RGD
UniProt
PMID:11788434 GO_REF:0000024 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        glomerulus development 73
          glomerulus vasculature development 30
            glomerular mesangium development 19
              glomerular mesangial cell differentiation + 6
              glomerular mesangial cell proliferation + 14
              mesonephric glomerular mesangium development + 0
              metanephric glomerular mesangium development + 5
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            urogenital system development 432
              renal system development 382
                kidney development 368
                  nephron development 166
                    glomerulus development 73
                      glomerulus vasculature development 30
                        glomerular mesangium development 19
                          glomerular mesangial cell differentiation + 6
                          glomerular mesangial cell proliferation + 14
                          mesonephric glomerular mesangium development + 0
                          metanephric glomerular mesangium development + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.