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ONTOLOGY REPORT - ANNOTATIONS


Term:cell differentiation involved in metanephros development
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Accession:GO:0072202 term browser browse the term
Definition:The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state.


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cell differentiation involved in metanephros development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 ISO (MGI:5006869|PMID:21523854) RGD PMID:21523854 MGI:5006869 NCBI chr 3:101,051,960...101,152,119
Ensembl chr 3:101,051,955...101,152,119
JBrowse link
mesenchymal to epithelial transition involved in metanephric renal vesicle formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smo smoothened, frizzled class receptor IEA
ISO
ISS
GO_REF:0000107
(MGI:3611729|PMID:16396903)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:16396903 GO_REF:0000024, GO_REF:0000107, MGI:3611729 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:10706139)
Ensembl
UniProt
RGD
PMID:10706139 GO_REF:0000024, GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Gdnf glial cell derived neurotrophic factor IDA
ISO
IEA
PMID:17522159
(PMID:10322633)
GO_REF:0000107
RGD
Ensembl
PMID:10322633, PMID:17522159 GO_REF:0000107, RGD:8656002 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist ISO (MGI:3714585|PMID:17522159) RGD PMID:17522159 MGI:3714585 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Pax2 paired box 2 ISO
ISS
(PMID:10322633)
GO_REF:0000024
RGD
UniProt
PMID:10322633 GO_REF:0000024 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 ISO (PMID:8861958) RGD PMID:8861958 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Sall1 spalt-like transcription factor 1 ISO (PMID:11511981)
(MGI:2149437|PMID:11688560)
RGD PMID:11511981, PMID:11688560 MGI:2149437 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039
JBrowse link
G Six2 SIX homeobox 2 ISO (PMID:10322633) RGD PMID:10322633 NCBI chr 6:8,952,572...8,955,893
Ensembl chr 6:8,952,572...8,956,276
JBrowse link
metanephric DCT cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou3f3 POU class 3 homeobox 3 ISS
ISO
IEA
GO_REF:0000024
(MGI:2669573|PMID:12925600)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12925600 GO_REF:0000024, GO_REF:0000107, MGI:2669573 NCBI chr 9:49,479,148...49,482,246
Ensembl chr 9:49,479,023...49,482,252
JBrowse link
metanephric glomerular mesangial cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B ISS
ISO
GO_REF:0000024
(MGI:3039044|PMID:15084468)
UniProt
RGD
PMID:15084468 GO_REF:0000024, MGI:3039044 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 molecule ISO (PMID:1868864) RGD PMID:1868864 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamb2 laminin subunit beta 2 IEA
ISO
GO_REF:0000107
MGI:2138070 (MGI:3664526|PMID:16886065)
Ensembl
RGD
PMID:16886065 GO_REF:0000107, MGI:3664526 NCBI chr 8:117,268,335...117,280,517
Ensembl chr 8:117,268,337...117,280,517
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin ISO (PMID:11786407) RGD PMID:11786407 NCBI chr13:73,929,136...73,941,522
Ensembl chr13:73,929,136...73,941,522
JBrowse link
metanephric interstitial fibroblast development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osr1 odd-skipped related transcription factor 1 ISS
ISO
GO_REF:0000024
(MGI:3826342|PMID:18835385)
UniProt
RGD
PMID:18835385 GO_REF:0000024, MGI:3826342 NCBI chr 6:35,314,431...35,321,458
Ensembl chr 6:35,314,444...35,321,667
JBrowse link
metanephric mesenchymal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osr1 odd-skipped related transcription factor 1 ISS
ISO
GO_REF:0000024
(MGI:3697513|PMID:16790474)
UniProt
RGD
PMID:16790474 GO_REF:0000024, MGI:3697513 NCBI chr 6:35,314,431...35,321,458
Ensembl chr 6:35,314,444...35,321,667
JBrowse link
G Pax2 paired box 2 ISS
ISO
GO_REF:0000024
(MGI:3663200|PMID:16368682)
UniProt
RGD
PMID:16368682 GO_REF:0000024, MGI:3663200 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Tcf21 transcription factor 21 ISS
ISO
GO_REF:0000024
(MGI:2651771|PMID:12619136)
UniProt
RGD
PMID:12619136 GO_REF:0000024, MGI:2651771 NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566
JBrowse link
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 IMP PMID:15843474 UniProt PMID:15843474 RGD:8554075 NCBI chr  X:72,128,996...72,133,692
Ensembl chr  X:72,128,994...72,133,692
JBrowse link
G Ctnnb1 catenin beta 1 IEA
ISO
GO_REF:0000107
(MGI:3714576|PMID:17537789)
Ensembl
RGD
PMID:17537789 GO_REF:0000107, MGI:3714576 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Sall1 spalt-like transcription factor 1 ISO MGI:3603818 (MGI:5563280|PMID:24550112) RGD PMID:24550112 MGI:5563280 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039
JBrowse link
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor IEA
ISO
GO_REF:0000107
(MGI:81286|PMID:8657306)
Ensembl
RGD
PMID:8657306 GO_REF:0000107, MGI:81286 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Lif LIF, interleukin 6 family cytokine ISO
IEA
(PMID:20624457)
GO_REF:0000107
RGD
Ensembl
PMID:20624457 GO_REF:0000107 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Pax2 paired box 2 ISS
ISO
GO_REF:0000024
UniProtKB:Q00288 (MGI:2445273|PMID:12435636)
UniProt
RGD
PMID:12435636 GO_REF:0000024, MGI:2445273 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 ISS
ISO
GO_REF:0000024
(MGI:2445273|PMID:12435636)
UniProt
RGD
PMID:12435636 GO_REF:0000024, MGI:2445273 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024, MGI:3704067 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024, MGI:3704067 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISS
ISO
GO_REF:0000024
(MGI:3795840|PMID:18431508)
UniProt
RGD
PMID:18431508 GO_REF:0000024, MGI:3795840 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt9b Wnt family member 9B ISO MGI:3526437 (MGI:3588895|PMID:16054034) RGD PMID:16054034 MGI:3588895 NCBI chr10:91,785,892...91,808,061
Ensembl chr10:91,785,893...91,807,937
JBrowse link
regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fat4 FAT atypical cadherin 4 ISO (MGI:5514437|PMID:23974041) RGD PMID:23974041 MGI:5514437 NCBI chr 2:125,751,818...125,879,398
Ensembl chr 2:125,752,130...125,879,387
JBrowse link
G Lif LIF, interleukin 6 family cytokine ISO
IEA
(PMID:20624457)
GO_REF:0000107
RGD
Ensembl
PMID:20624457 GO_REF:0000107 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Pax2 paired box 2 ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024, MGI:3704067 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 ISS
ISO
GO_REF:0000024
(MGI:3704067|PMID:17314325)
UniProt
RGD
PMID:17314325 GO_REF:0000024, MGI:3704067 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 ISO MGI:103262 (MGI:5514437|PMID:23974041) RGD PMID:23974041 MGI:5514437 NCBI chr 2:147,577,149...147,693,033
Ensembl chr 2:147,577,089...147,693,082
JBrowse link
G Yap1 Yes1 associated transcriptional regulator ISO MGI:1917649 (MGI:5514437|PMID:23974041) RGD PMID:23974041 MGI:5514437 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    developmental process 6828
      cellular developmental process 4458
        cell differentiation 4363
          cell differentiation involved in kidney development 57
            cell differentiation involved in metanephros development 24
              mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis 0
              mesenchymal to epithelial transition involved in metanephros morphogenesis + 12
              metanephric DCT cell differentiation + 3
              metanephric glomerular epithelial cell differentiation + 3
              metanephric interstitial fibroblast differentiation + 1
              metanephric juxtaglomerulus cell differentiation + 0
              metanephric mesangial cell differentiation + 2
              metanephric mesenchymal cell differentiation 3
              metanephric nephron tubule epithelial cell differentiation + 6
Path 2
Term Annotations click to browse term
  biological_process 20030
    developmental process 6828
      anatomical structure development 6270
        multicellular organism development 5744
          system development 5280
            urogenital system development 432
              renal system development 382
                kidney development 368
                  cell differentiation involved in kidney development 57
                    cell differentiation involved in metanephros development 24
                      mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis 0
                      mesenchymal to epithelial transition involved in metanephros morphogenesis + 12
                      metanephric DCT cell differentiation + 3
                      metanephric glomerular epithelial cell differentiation + 3
                      metanephric interstitial fibroblast differentiation + 1
                      metanephric juxtaglomerulus cell differentiation + 0
                      metanephric mesangial cell differentiation + 2
                      metanephric mesenchymal cell differentiation 3
                      metanephric nephron tubule epithelial cell differentiation + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.