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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric nephron development
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Accession:GO:0072210 term browser browse the term
Definition:The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.


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metanephric nephron development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxd1 forkhead box D1 JBrowse link 2 28,460,068 28,462,488 RGD:1600115
RGD:1624291
G Tfap2a transcription factor AP-2 alpha JBrowse link 17 24,653,342 24,670,457 RGD:1624291
G Tfap2b transcription factor AP-2 beta JBrowse link 9 25,410,669 25,440,568 RGD:1624291
RGD:1600115
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
mesenchymal to epithelial transition involved in metanephric renal vesicle formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1600115
RGD:1624291
mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:8656002
RGD:1624291
RGD:1600115
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
RGD:1600115
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
RGD:1600115
G Six2 SIX homeobox 2 JBrowse link 6 8,952,572 8,955,893 RGD:1624291
metanephric comma-shaped body morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lhx1 LIM homeobox 1 JBrowse link 10 71,843,991 71,849,293 RGD:8553921
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:8554631
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
metanephric distal tubule morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pkd1 polycystin 1, transient receptor potential channel interacting JBrowse link 10 13,914,057 13,962,008 RGD:1624291
RGD:1600115
metanephric glomerular basement membrane development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamb2 laminin subunit beta 2 JBrowse link 8 117,268,335 117,280,517 RGD:1600115
RGD:1624291
metanephric glomerular capillary formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:1600115
RGD:1624291
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1624291
RGD:1600115
G Tcf21 transcription factor 21 JBrowse link 1 23,906,717 23,909,576 RGD:1624291
RGD:1600115
metanephric glomerular endothelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1624291
metanephric glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1624291
RGD:1600115
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd34 CD34 molecule JBrowse link 13 113,691,842 113,711,259 RGD:1624291
RGD:1600115
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1624291
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1624291
RGD:1600115
metanephric glomerular mesangium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1624291
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamb2 laminin subunit beta 2 JBrowse link 8 117,268,335 117,280,517 RGD:1624291
RGD:1600115
G Nphs2 NPHS2 stomatin family member, podocin JBrowse link 13 73,929,136 73,941,522 RGD:1624291
RGD:1600115
metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 JBrowse link 3 101,051,960 101,152,119 RGD:1624291
RGD:1600115
G Lhx1 LIM homeobox 1 JBrowse link 10 71,843,991 71,849,293 RGD:8553921
metanephric glomerulus morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:8554631
metanephric glomerulus vasculature development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp1 aquaporin 1 (Colton blood group) JBrowse link 4 85,551,503 85,563,683 RGD:1624291
RGD:1600115
G Osr1 odd-skipped related transcription factor 1 JBrowse link 6 35,314,431 35,321,458 RGD:1624291
RGD:1600115
metanephric nephron morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
RGD:1600115
metanephric nephron tubule formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
G Sox8 SRY-box transcription factor 8 JBrowse link 10 14,932,348 14,937,336 RGD:1624291
RGD:1600115
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
metanephric nephron tubule morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1600115
RGD:1624291
G Hes5 hes family bHLH transcription factor 5 JBrowse link 5 172,364,421 172,365,188 RGD:1624291
RGD:1600115
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 JBrowse link 3 101,051,960 101,152,119 RGD:1624291
RGD:1600115
metanephric renal vesicle morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lhx1 LIM homeobox 1 JBrowse link 10 71,843,991 71,849,293 RGD:1624291
RGD:1600115
metanephric S-shaped body morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lhx1 LIM homeobox 1 JBrowse link 10 71,843,991 71,849,293 RGD:8553921
RGD:1624291
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:8554631
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
RGD:1600115
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
RGD:1600115
negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 JBrowse link X 72,128,996 72,133,692 RGD:8554075
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
negative regulation of metanephric comma-shaped body morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
RGD:1600115
negative regulation of metanephric S-shaped body morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:8553929
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:1600115
RGD:1624291
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:1624291
RGD:1600115
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:1624291
RGD:1600115
positive regulation of metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agtr2 angiotensin II receptor, type 2 JBrowse link X 119,389,480 119,393,845 RGD:1624291
RGD:1600115
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:1624291
RGD:1600115
proximal/distal pattern formation involved in metanephric nephron development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Irx1 iroquois homeobox 1 JBrowse link 1 33,910,912 33,916,741 RGD:1624291
RGD:1600115
G Irx2 iroquois homeobox 2 JBrowse link 1 33,270,388 33,275,868 RGD:1624291
RGD:1600115
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt9b Wnt family member 9B JBrowse link 10 91,785,892 91,808,061 RGD:1624291
RGD:1600115
ureteric bud invasion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fmn1 formin 1 JBrowse link 3 104,783,093 105,170,761 RGD:1624291
G Kif26b kinesin family member 26B JBrowse link 13 96,775,356 97,173,469 RGD:1624291
RGD:1600115
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    developmental process 6505
      anatomical structure development 5993
        nephron development 161
          metanephric nephron development 42
            metanephric extraglomerular mesangial cell proliferation involved in metanephros development 0
            metanephric glomerulus development + 17
            metanephric long nephron development + 0
            metanephric nephron morphogenesis + 25
            metanephric short nephron development + 0
            proximal/distal pattern formation involved in metanephric nephron development + 2
Path 2
Term Annotations click to browse term
  biological_process 18008
    developmental process 6505
      anatomical structure development 5993
        multicellular organism development 5478
          system development 5028
            urogenital system development 408
              renal system development 358
                kidney development 338
                  nephron development 161
                    metanephric nephron development 42
                      metanephric extraglomerular mesangial cell proliferation involved in metanephros development 0
                      metanephric glomerulus development + 17
                      metanephric long nephron development + 0
                      metanephric nephron morphogenesis + 25
                      metanephric short nephron development + 0
                      proximal/distal pattern formation involved in metanephric nephron development + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.