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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of metanephros development
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Accession:GO:0072215 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.


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negative regulation of apoptotic process involved in metanephric collecting duct development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
negative regulation of apoptotic process involved in metanephric nephron tubule development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
negative regulation of mesenchymal cell apoptotic process involved in metanephros development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hnf1b HNF1 homeobox B JBrowse link 10 71,159,863 71,218,902 RGD:1624291
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 JBrowse link X 72,128,996 72,133,692 RGD:8554075
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
negative regulation of metanephric comma-shaped body morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
RGD:1600115
negative regulation of metanephric mesenchymal cell migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:1624291
RGD:1600115
negative regulation of metanephric S-shaped body morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:8553929
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:1600115
RGD:1624291
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:1624291
RGD:1600115
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
positive regulation of metanephric cap mesenchymal cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:1624291
RGD:1600115
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:1624291
RGD:1600115
positive regulation of metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agtr2 angiotensin II receptor, type 2 JBrowse link X 119,389,480 119,393,845 RGD:1624291
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:1624291
positive regulation of metanephric mesenchymal cell migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:8554838
RGD:1624291
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfa platelet derived growth factor subunit A JBrowse link 12 17,734,141 17,756,186 RGD:1600115
RGD:1624291
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1600115
RGD:1624291
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1624291
RGD:1600115
positive regulation of metanephric ureteric bud development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
RGD:1600115
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt9b Wnt family member 9B JBrowse link 10 91,785,892 91,808,061 RGD:1624291
regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fat4 FAT atypical cadherin 4 JBrowse link 2 125,751,818 125,879,398 RGD:1624291
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:1624291
RGD:1600115
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
G Wwtr1 WW domain containing transcription regulator 1 JBrowse link 2 147,577,149 147,693,033 RGD:1624291
G Yap1 Yes1 associated transcriptional regulator JBrowse link 8 6,133,014 6,204,240 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    multicellular organismal process 8814
      multicellular organism development 5579
        regulation of multicellular organismal development 2233
          regulation of kidney development 61
            regulation of metanephros development 22
              negative regulation of metanephros development + 9
              positive regulation of metanephros development + 13
              regulation of apoptotic process involved in metanephric collecting duct development + 2
              regulation of apoptotic process involved in metanephric nephron tubule development + 2
              regulation of mesenchymal cell apoptotic process involved in metanephros development + 4
              regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis + 8
              regulation of metanephric DCT cell differentiation + 2
              regulation of metanephric S-shaped body morphogenesis + 1
              regulation of metanephric cap mesenchymal cell proliferation + 1
              regulation of metanephric comma-shaped body morphogenesis + 1
              regulation of metanephric glomerulus development + 6
              regulation of metanephric mesenchymal cell migration + 4
              regulation of metanephric nephron tubule epithelial cell differentiation + 6
              regulation of metanephric ureteric bud development + 1
Path 2
Term Annotations click to browse term
  biological_process 19336
    developmental process 6638
      anatomical structure development 6107
        multicellular organism development 5579
          system development 5100
            urogenital system development 405
              renal system development 356
                kidney development 341
                  regulation of kidney development 61
                    regulation of metanephros development 22
                      negative regulation of metanephros development + 9
                      positive regulation of metanephros development + 13
                      regulation of apoptotic process involved in metanephric collecting duct development + 2
                      regulation of apoptotic process involved in metanephric nephron tubule development + 2
                      regulation of mesenchymal cell apoptotic process involved in metanephros development + 4
                      regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis + 8
                      regulation of metanephric DCT cell differentiation + 2
                      regulation of metanephric S-shaped body morphogenesis + 1
                      regulation of metanephric cap mesenchymal cell proliferation + 1
                      regulation of metanephric comma-shaped body morphogenesis + 1
                      regulation of metanephric glomerulus development + 6
                      regulation of metanephric mesenchymal cell migration + 4
                      regulation of metanephric nephron tubule epithelial cell differentiation + 6
                      regulation of metanephric ureteric bud development + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.