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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric distal convoluted tubule development
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Accession:GO:0072221 term browser browse the term
Definition:The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.


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metanephric distal convoluted tubule development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calb1 calbindin 1 JBrowse link 5 29,538,380 29,562,774 RGD:1624291
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
G Umod uromodulin JBrowse link 1 189,186,027 189,199,939 RGD:1600115
RGD:1624291
metanephric DCT cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pou3f3 POU class 3 homeobox 3 JBrowse link 9 49,479,148 49,482,246 RGD:1624291
RGD:1600115
positive regulation of metanephric DCT cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    developmental process 6638
      anatomical structure development 6107
        tube development 1178
          metanephric tubule development 24
            metanephric nephron tubule development 20
              metanephric distal convoluted tubule development 5
                metanephric DCT cell differentiation + 3
                metanephric early distal convoluted tubule development 0
                metanephric late distal convoluted tubule development 0
Path 2
Term Annotations click to browse term
  biological_process 19336
    developmental process 6638
      anatomical structure development 6107
        multicellular organism development 5579
          system development 5100
            urogenital system development 405
              renal system development 356
                kidney development 341
                  nephron development 162
                    nephron epithelium development 123
                      nephron tubule development 105
                        distal tubule development 12
                          distal convoluted tubule development 5
                            metanephric distal convoluted tubule development 5
                              metanephric DCT cell differentiation + 3
                              metanephric early distal convoluted tubule development 0
                              metanephric late distal convoluted tubule development 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.