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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric glomerulus development
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Accession:GO:0072224 term browser browse the term
Definition:The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.
Synonyms:exact_synonym: metanephric glomerular development


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metanephric glomerulus development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 ISO (MGI:MGI:5006869|PMID:21523854) RGD PMID:21523854 MGI:MGI:5006869 NCBI chr 3:101,051,960...101,152,119
Ensembl chr 3:101,051,955...101,152,119
JBrowse link
G Lhx1 LIM homeobox 1 IEP PMID:9496787 UniProt PMID:9496787 RGD:8553921 NCBI chr10:71,843,991...71,849,293
Ensembl chr10:71,843,991...71,849,293
JBrowse link
metanephric glomerular basement membrane development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamb2 laminin subunit beta 2 IEA
ISO
GO_REF:0000107
MGI:MGI:2138070 (MGI:MGI:3664526|PMID:16886065), (MGI:MGI:75217|PMID:7670489)
Ensembl
RGD
PMID:7670489, PMID:16886065 GO_REF:0000107, MGI:MGI:3664526, MGI:MGI:75217 NCBI chr 8:117,268,335...117,280,517
Ensembl chr 8:117,268,337...117,280,517
JBrowse link
metanephric glomerular capillary formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfra platelet derived growth factor receptor alpha IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
UniProtKB:P05622 (MGI:MGI:1931346|PMID:11239463)
Ensembl
UniProt
RGD
PMID:11239463 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1931346 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO
ISS
UniProtKB:P26618 (MGI:MGI:1931346|PMID:11239463)
GO_REF:0000024
RGD
UniProt
PMID:11239463 GO_REF:0000024, MGI:MGI:1931346 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Tcf21 transcription factor 21 ISO
ISS
(MGI:MGI:2651771|PMID:12619136)
GO_REF:0000024
RGD
UniProt
PMID:12619136 GO_REF:0000024, MGI:MGI:2651771 NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566
JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B ISO (PMID:9693135) RGD PMID:9693135 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
metanephric glomerular mesangial cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B ISO
ISS
(MGI:MGI:3039044|PMID:15084468)
GO_REF:0000024
RGD
UniProt
PMID:15084468 GO_REF:0000024, MGI:MGI:3039044 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 molecule ISO (PMID:1868864) RGD PMID:1868864 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B ISO (MGI:MGI:1289803|PMID:9693135) RGD PMID:9693135 MGI:MGI:1289803 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO
ISS
(MGI:MGI:1289803|PMID:9693135)
GO_REF:0000024
RGD
UniProt
PMID:9693135 GO_REF:0000024, MGI:MGI:1289803 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
metanephric glomerular mesangium development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfrb platelet derived growth factor receptor beta ISO (PMID:9693135) RGD PMID:9693135 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamb2 laminin subunit beta 2 ISO
IEA
MGI:MGI:2138070 (MGI:MGI:3664526|PMID:16886065)
GO_REF:0000107
RGD
Ensembl
PMID:16886065 GO_REF:0000107, MGI:MGI:3664526 NCBI chr 8:117,268,335...117,280,517
Ensembl chr 8:117,268,337...117,280,517
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin ISO (PMID:11786407) RGD PMID:11786407 NCBI chr13:73,929,136...73,941,522
Ensembl chr13:73,929,136...73,941,522
JBrowse link
metanephric glomerulus morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfrb platelet derived growth factor receptor beta IEP PMID:10734101 UniProt PMID:10734101 RGD:8554631 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
metanephric glomerulus vasculature development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 ISO (PMID:18618131) RGD PMID:18618131 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Osr1 odd-skipped related transcription factor 1 ISO
ISS
(MGI:MGI:3826342|PMID:18835385)
GO_REF:0000024
RGD
UniProt
PMID:18835385 GO_REF:0000024, MGI:MGI:3826342 NCBI chr 6:35,314,431...35,321,458
Ensembl chr 6:35,314,444...35,321,667
JBrowse link
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wt1 WT1 transcription factor ISO
ISS
(MGI:MGI:1332959|PMID:10077614)
GO_REF:0000024
RGD
UniProt
PMID:10077614 GO_REF:0000024, MGI:MGI:1332959 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 IMP PMID:8910451 UniProt PMID:8910451 RGD:8553929 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO
ISS
(MGI:MGI:3795840|PMID:18431508)
GO_REF:0000024
RGD
UniProt
PMID:18431508 GO_REF:0000024, MGI:MGI:3795840 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
positive regulation of metanephric glomerulus development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 ISO (MGI:MGI:3808848|PMID:18607644) RGD PMID:18607644 MGI:MGI:3808848 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Pax2 paired box 2 ISO
ISS
(MGI:MGI:3697544|PMID:17047028)
GO_REF:0000024
RGD
UniProt
PMID:17047028 GO_REF:0000024, MGI:MGI:3697544 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Ret ret proto-oncogene ISO (MGI:MGI:3697544|PMID:17047028) RGD PMID:17047028 MGI:MGI:3697544 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        glomerulus development 73
          metanephric glomerulus development 17
            metanephric glomerular basement membrane development 1
            metanephric glomerular epithelium development + 4
            metanephric glomerulus morphogenesis + 3
            metanephric glomerulus vasculature development + 9
            negative regulation of metanephric glomerulus development + 1
            positive regulation of metanephric glomerulus development + 5
            regulation of metanephric glomerulus development + 6
Path 2
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            urogenital system development 433
              renal system development 383
                kidney development 369
                  nephron development 166
                    metanephric nephron development 42
                      metanephric glomerulus development 17
                        metanephric glomerular basement membrane development 1
                        metanephric glomerular epithelium development + 4
                        metanephric glomerulus morphogenesis + 3
                        metanephric glomerulus vasculature development + 9
                        negative regulation of metanephric glomerulus development + 1
                        positive regulation of metanephric glomerulus development + 5
                        regulation of metanephric glomerulus development + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.