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ONTOLOGY REPORT - ANNOTATIONS


Term:metanephric glomerulus development
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Accession:GO:0072224 term browser browse the term
Definition:The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.
Synonyms:exact_synonym: metanephric glomerular development


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metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgr4 leucine rich repeat containing G protein-coupled receptor 4 JBrowse link NW_004936540 5,752,319 5,846,074 RGD:9068941
G Lhx1 LIM homeobox 1 JBrowse link NW_004936490 1,324,378 1,332,177 RGD:9068941
metanephric glomerular basement membrane development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamb2 laminin subunit beta 2 JBrowse link NW_004936529 826,178 841,304 RGD:9068941
metanephric glomerular capillary formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfra platelet derived growth factor receptor alpha JBrowse link NW_004936482 16,804,129 16,853,539 RGD:9068941
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004936504 4,762,251 4,799,789 RGD:9068941
G Tcf21 transcription factor 21 JBrowse link NW_004936560 1,733,903 1,736,895 RGD:9068941
metanephric glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004936492 2,353,840 2,368,573 RGD:9068941
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd34 CD34 molecule JBrowse link NW_004936557 5,030,788 5,051,864 RGD:9068941
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004936504 4,762,251 4,799,789 RGD:9068941
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamb2 laminin subunit beta 2 JBrowse link NW_004936529 826,178 841,304 RGD:9068941
G Nphs2 NPHS2 stomatin family member, podocin JBrowse link NW_004936481 9,496,083 9,516,086 RGD:9068941
metanephric glomerulus vasculature development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Osr1 odd-skipped related transcription factor 1 JBrowse link NW_004936493 11,888,024 11,895,058 RGD:9068941
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wt1 WT1 transcription factor JBrowse link NW_004936533 5,411,949 5,459,693 RGD:9068941
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Egr1 early growth response 1 JBrowse link NW_004936531 7,625,956 7,629,041 RGD:9068941
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link NW_004936578 3,168,599 3,179,369 RGD:9068941
positive regulation of metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agtr2 angiotensin II receptor type 2 JBrowse link NW_004936479 13,252,678 13,255,570 RGD:9068941
G Pax2 paired box 2 JBrowse link NW_004936600 4,850,594 4,939,010 RGD:9068941
G Ret ret proto-oncogene JBrowse link NW_004936617 2,927,185 2,980,594 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14725
    developmental process 5760
      anatomical structure development 5409
        glomerulus development 61
          metanephric glomerulus development 16
            metanephric glomerular basement membrane development 1
            metanephric glomerular epithelium development + 3
            metanephric glomerulus morphogenesis + 3
            metanephric glomerulus vasculature development + 8
            negative regulation of metanephric glomerulus development + 1
            positive regulation of metanephric glomerulus development + 5
            regulation of metanephric glomerulus development + 6
Path 2
Term Annotations click to browse term
  biological_process 14725
    developmental process 5760
      anatomical structure development 5409
        multicellular organism development 4972
          system development 4455
            urogenital system development 325
              renal system development 288
                kidney development 273
                  nephron development 139
                    metanephric nephron development 39
                      metanephric glomerulus development 16
                        metanephric glomerular basement membrane development 1
                        metanephric glomerular epithelium development + 3
                        metanephric glomerulus morphogenesis + 3
                        metanephric glomerulus vasculature development + 8
                        negative regulation of metanephric glomerulus development + 1
                        positive regulation of metanephric glomerulus development + 5
                        regulation of metanephric glomerulus development + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.