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ONTOLOGY REPORT - ANNOTATIONS


Term:signal transduction involved in DNA damage checkpoint
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Accession:GO:0072422 term browser browse the term
Definition:A signal transduction process that contributes to a DNA damage checkpoint.


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signal transduction involved in DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc5l cell division cycle 5-like JBrowse link 9 17,949,764 17,988,514 RGD:1624291
RGD:1600115
G Prpf19 pre-mRNA processing factor 19 JBrowse link 1 226,947,065 226,958,147 RGD:1624291
RGD:1600115
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp2 caspase 2 JBrowse link 4 71,652,358 71,670,228 RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain JBrowse link 7 36,395,665 36,408,588 RGD:1624291
RGD:13792537
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:1624291
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:1624291
G Pidd1 p53-induced death domain protein 1 JBrowse link 1 214,418,751 214,423,959 RGD:1624291
G Pml PML nuclear body scaffold JBrowse link 8 63,002,515 63,034,310 RGD:1624291
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma JBrowse link 6 134,804,128 134,941,912 RGD:1624291
G Rbm38 RNA binding motif protein 38 JBrowse link 3 171,037,891 171,050,500 RGD:1624291
G Rpl26 ribosomal protein L26 JBrowse link 10 55,492,417 55,495,547 RGD:1624291
G Sox4 SRY-box transcription factor 4 JBrowse link 17 37,615,022 37,619,728 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
regulation of signal transduction involved in mitotic G2 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rint1 RAD50 interactor 1 JBrowse link 4 7,851,602 7,885,446 RGD:1624291
RGD:13792537
signal transduction involved in G2 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abraxas1 abraxas 1, BRCA1 A complex subunit JBrowse link 14 10,424,674 10,439,010 RGD:1600115
RGD:1624291
G Babam1 BRISC and BRCA1 A complex member 1 JBrowse link 16 19,792,720 19,798,886 RGD:1600115
RGD:1624291
G Babam2 BRISC and BRCA1 A complex member 2 JBrowse link 6 25,666,654 26,135,888 RGD:1624291
RGD:1600115
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1600115
RGD:1624291
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 JBrowse link 9 9,863,380 9,865,920 RGD:1600115
RGD:1624291
G Cdc14b cell division cycle 14B JBrowse link 17 1,709,703 1,797,732 RGD:1624291
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:1624291
G Dtl denticleless E3 ubiquitin protein ligase homolog JBrowse link 13 110,219,276 110,257,345 RGD:1624291
G Fzr1 fizzy and cell division cycle 20 related 1 JBrowse link 7 11,201,690 11,213,614 RGD:1624291
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:1600115
RGD:1624291
G Uimc1 ubiquitin interaction motif containing 1 JBrowse link 17 10,061,915 10,130,921 RGD:1600115
RGD:1624291
signal transduction involved in intra-S DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:1624291
signal transduction involved in mitotic G1 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
signal transduction involved in mitotic G2 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      cell cycle checkpoint 188
        DNA integrity checkpoint 126
          DNA damage checkpoint 116
            signal transduction involved in DNA damage checkpoint 30
              intracellular signal transduction involved in G1 DNA damage checkpoint + 13
              signal transduction involved in G2 DNA damage checkpoint + 13
              signal transduction involved in mitotic DNA damage checkpoint + 16
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          negative regulation of cellular process 5079
            negative regulation of cell cycle 461
              cell cycle checkpoint 188
                signal transduction involved in cell cycle checkpoint 31
                  signal transduction involved in DNA integrity checkpoint 30
                    signal transduction involved in DNA damage checkpoint 30
                      intracellular signal transduction involved in G1 DNA damage checkpoint + 13
                      signal transduction involved in G2 DNA damage checkpoint + 13
                      signal transduction involved in mitotic DNA damage checkpoint + 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.