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ONTOLOGY REPORT - ANNOTATIONS


Term:pyridine-containing compound metabolic process
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Accession:GO:0072524 term browser browse the term
Definition:The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
Synonyms:exact_synonym: pyridine and derivative metabolic process;   pyridine-containing compound metabolism


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'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Kmo kynurenine 3-monooxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Aspdh aspartate dehydrogenase domain containing IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:100,471,066...100,473,327
Ensembl chr 1:100,470,722...100,473,459
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase ISO (PMID:28792876) RGD PMID:28792876 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Kynu kynureninase ISS
ISO
GO_REF:0000024
(PMID:28792876)
UniProt
RGD
PMID:28792876 GO_REF:0000024 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Nadsyn1 NAD synthetase 1 IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 1:216,985,710...217,013,743
Ensembl chr 1:216,985,714...217,013,702
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IEA
ISO
GO_REF:0000041
(MGI:3522067|PMID:15381699)
UniProt
RGD
PMID:15381699 GO_REF:0000041, MGI:3522067 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Naprt nicotinate phosphoribosyltransferase IDA
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:8694849, PMID:21873635 GO_REF:0000041, RGD:2289495, RGD:13792537 NCBI chr 7:116,922,979...116,926,436
Ensembl chr 7:116,922,944...116,926,555
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 IEA
IBA
ISO
GO_REF:0000041
PMID:21873635
(MGI:3522067|PMID:15381699), (MGI:3654729|PMID:16914673), (MGI:6206974|PMID:27735788)
UniProt
RGD
PMID:15381699, PMID:16914673, PMID:27735788, PMID:21873635 GO_REF:0000041, MGI:3522067, MGI:3654729, MGI:6206974, RGD:13792537 NCBI chr 5:166,409,460...166,430,291
Ensembl chr 5:166,409,461...166,430,254
JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 IMP
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:22449973, PMID:21873635 GO_REF:0000041, RGD:13782043, RGD:13792537 NCBI chr13:70,379,346...70,559,311
Ensembl chr13:70,379,346...70,559,458
JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 IEA
IBA
ISO
GO_REF:0000041
PMID:21873635
(MGI:3654729|PMID:16914673)
UniProt
RGD
PMID:16914673, PMID:21873635 GO_REF:0000041, MGI:3654729, RGD:13792537 NCBI chr 8:106,317,038...106,429,535
Ensembl chr 8:106,317,124...106,429,522
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:234,721,992...234,749,452
Ensembl chr 1:234,721,974...234,749,447
JBrowse link
G Qprt quinolinate phosphoribosyltransferase IDA
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:8694849, PMID:21873635 GO_REF:0000041, RGD:2289495, RGD:13792537 NCBI chr 1:198,544,262...198,559,556
Ensembl chr 1:198,544,262...198,559,568
JBrowse link
NAD catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Art2b ADP-ribosyltransferase 2b ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:166,665,029...166,685,097
Ensembl chr 1:166,667,169...166,677,026
JBrowse link
G Nudt12 nudix hydrolase 12 ISO
IBA
(PMID:12790796)
PMID:21873635
RGD PMID:12790796, PMID:21873635 RGD:13792537 NCBI chr 9:105,680,603...105,693,374
Ensembl chr 9:105,680,670...105,693,357
JBrowse link
G Nudt17 nudix hydrolase 17 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:198,831,546...198,836,191
Ensembl chr 2:198,831,546...198,834,925
JBrowse link
G Sarm1 sterile alpha and TIR motif containing 1 ISO (PMID:25908823), (PMID:27671644), (PMID:28334607), (PMID:31128467), (PMID:31439792), (PMID:31439793)
(MGI:6114587|PMID:28334607), (MGI:6206974|PMID:27735788)
RGD PMID:25908823, PMID:27671644, PMID:27735788, PMID:28334607, PMID:31128467, PMID:31439792, PMID:31439793 MGI:6114587, MGI:6206974 NCBI chr10:65,742,343...65,766,050
Ensembl chr10:65,742,343...65,766,050
JBrowse link
NAD salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naprt nicotinate phosphoribosyltransferase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:116,922,979...116,926,436
Ensembl chr 7:116,922,944...116,926,555
JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase ISO MGI:2182739 (MGI:1097071|PMID:9330624), (MGI:1202104|PMID:9539108), (MGI:1261671|PMID:9627357), (MGI:1349468|PMID:3377761), (MGI:2387959|PMID:10627286), (MGI:3522057|PMID:15271799), (MGI:3607389|PMID:14757696), (MGI:3694178|PMID:15998684), (MGI:49164|PMID:1953691), (MGI:54902|PMID:7439685), (MGI:85983|PMID:9067418), (MGI:87492|PMID:9169132) RGD PMID:1953691, PMID:3377761, PMID:7439685, PMID:9067418, PMID:9169132, PMID:9330624, PMID:9539108, PMID:9627357, PMID:10627286, PMID:14757696, PMID:15271799, PMID:15998684 MGI:1097071, MGI:1202104, MGI:1261671, MGI:1349468, MGI:2387959, MGI:3522057, MGI:3607389, MGI:3694178, MGI:49164, MGI:54902, MGI:85983, MGI:87492 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IMP RGD PMID:21641335 RGD:11522736 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Nadk NAD kinase IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:22550069, PMID:21873635 RGD:13703105, RGD:13792537 NCBI chr 5:172,984,930...173,015,505
Ensembl chr 5:172,986,291...173,015,494
JBrowse link
G Nadk2 NAD kinase 2, mitochondrial IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002, GO_REF:0000104 NCBI chr 2:58,462,588...58,504,735
Ensembl chr 2:58,462,588...58,504,728
JBrowse link
NADP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt12 nudix hydrolase 12 ISO
IBA
(PMID:12790796)
PMID:21873635
RGD PMID:12790796, PMID:21873635 RGD:13792537 NCBI chr 9:105,680,603...105,693,374
Ensembl chr 9:105,680,670...105,693,357
JBrowse link
G Nudt13 nudix hydrolase 13 ISO (MGI:6368098|PMID:28755312) RGD PMID:28755312 MGI:6368098 NCBI chr15:4,434,341...4,454,871
Ensembl chr15:4,434,313...4,454,958
JBrowse link
G Nudt17 nudix hydrolase 17 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:198,831,546...198,836,191
Ensembl chr 2:198,831,546...198,834,925
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase ISO
ISS
IEA
(PMID:12140278)
GO_REF:0000024
GO_REF:0000104
RGD
UniProt
PMID:12140278 GO_REF:0000024, GO_REF:0000104 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
nicotinamide nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naxd NAD(P)HX dehydratase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr16:83,326,228...83,342,711
Ensembl chr16:83,326,301...83,342,667
JBrowse link
G Naxe NAD(P)HX epimerase ISO (PMID:27616477) RGD PMID:27616477 NCBI chr 2:187,424,319...187,426,410
Ensembl chr 2:187,424,327...187,426,375
JBrowse link
nicotinamide riboside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtap methylthioadenosine phosphorylase NOT ISO (PMID:19001417) RGD PMID:19001417 NCBI chr 5:107,711,077...107,777,530
Ensembl chr 5:107,711,077...107,777,530
JBrowse link
G Pnp purine nucleoside phosphorylase ISO (PMID:19001417) RGD PMID:19001417 NCBI chr15:27,875,883...27,883,566
Ensembl chr15:27,875,911...27,883,350
JBrowse link
pyridoxal 5'-phosphate salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxk pyridoxal kinase IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr20:10,930,651...10,952,194
Ensembl chr20:10,930,518...10,952,391
JBrowse link
G RGD1566085 similar to pyridoxal (pyridoxine, vitamin B6) kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:10,883,952...10,912,870
Ensembl chr20:10,889,573...10,912,769
JBrowse link
pyridoxal phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxk pyridoxal kinase IDA RGD PMID:2988502 RGD:2303018 NCBI chr20:10,930,651...10,952,194
Ensembl chr20:10,930,518...10,952,391
JBrowse link
G Pnpo pyridoxamine 5'-phosphate oxidase ISO
IBA
(PMID:12824491)
PMID:21873635
RGD PMID:12824491, PMID:21873635 RGD:13792537 NCBI chr10:84,874,926...84,881,190
Ensembl chr10:84,874,927...84,881,190
JBrowse link
pyridoxal phosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxp pyridoxal phosphatase ISS
ISO
IEA
GO_REF:0000024
(MGI:5545857|PMID:24338473)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:24338473 GO_REF:0000024, GO_REF:0000107, MGI:5545857 NCBI chr 7:120,140,460...120,145,908
Ensembl chr 7:120,140,460...120,145,908
JBrowse link
pyridoxine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpo pyridoxamine 5'-phosphate oxidase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:84,874,926...84,881,190
Ensembl chr10:84,874,927...84,881,190
JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IEA
ISO
GO_REF:0000104
(PMID:28792876)
UniProt
RGD
PMID:28792876 GO_REF:0000104 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Htt huntingtin ISO MGI:1861934|MGI:1861935 (MGI:3653320|PMID:16697652) RGD PMID:16697652 MGI:3653320 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Kmo kynurenine 3-monooxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase ISO (PMID:9291104) RGD PMID:9291104 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
quinolinate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Qprt quinolinate phosphoribosyltransferase IBA
ISO
PMID:21873635
(PMID:24038671), (PMID:3409840), (PMID:9473669)
RGD PMID:3409840, PMID:9473669, PMID:24038671, PMID:21873635 RGD:13792537 NCBI chr 1:198,544,262...198,559,556
Ensembl chr 1:198,544,262...198,559,568
JBrowse link
quinolinate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:2940338, PMID:21873635, PMID:9870556, PMID:3112306 RGD:2290301, RGD:13792537, RGD:2290370, RGD:2290302 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Qprt quinolinate phosphoribosyltransferase IDA RGD PMID:8694849 RGD:2289495 NCBI chr 1:198,544,262...198,559,556
Ensembl chr 1:198,544,262...198,559,568
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    metabolic process 12185
      nitrogen compound metabolic process 10212
        cellular nitrogen compound metabolic process 6678
          pyridine-containing compound metabolic process 34
            2,5-dihydroxypyridine metabolic process + 0
            aspyridone A metabolic process + 0
            aspyridone B metabolic process + 0
            nicotinamide metabolic process + 0
            nicotinate metabolic process + 0
            picolinic acid metabolic process + 0
            pyridine metabolic process + 0
            pyridine nucleoside metabolic process + 2
            pyridine nucleotide metabolic process + 26
            pyridine-containing compound biosynthetic process + 24
            pyridine-containing compound catabolic process + 9
            quinolinate metabolic process + 6
            vitamin B6 metabolic process + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.