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ONTOLOGY REPORT - ANNOTATIONS


Term:pyridine-containing compound metabolic process
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Accession:GO:0072524 term browser browse the term
Definition:The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
Synonyms:exact_synonym: pyridine and derivative metabolic process;   pyridine-containing compound metabolism


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'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AFMID arylformamidase JBrowse link 17 78,185,102 78,207,702 RGD:2290271
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 2 42,767,087 42,801,002 RGD:2290271
G IDO1 indoleamine 2,3-dioxygenase 1 JBrowse link 8 39,913,891 39,928,790 RGD:2290271
G IDO2 indoleamine 2,3-dioxygenase 2 JBrowse link 8 39,934,955 40,016,391 RGD:2290271
G KMO kynurenine 3-monooxygenase JBrowse link 1 241,531,883 241,595,642 RGD:2290271
G KYNU kynureninase JBrowse link 2 142,877,664 143,055,833 RGD:2290271
NAD biosynthesis via nicotinamide riboside salvage pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NAMPT nicotinamide phosphoribosyltransferase JBrowse link 7 106,248,298 106,284,983 RGD:2290271
G NAPRT nicotinate phosphoribosyltransferase JBrowse link 8 143,574,585 143,578,349 RGD:2290271
G NAXD NAD(P)HX dehydratase JBrowse link 13 110,615,460 110,639,996 RGD:2290271
G NAXE NAD(P)HX epimerase JBrowse link 1 156,591,776 156,599,818 RGD:2290271
G NNMT nicotinamide N-methyltransferase JBrowse link 11 114,257,806 114,313,536 RGD:2290271
G NUDT12 nudix hydrolase 12 JBrowse link 5 103,548,855 103,562,805 RGD:2290271
G PARP10 poly(ADP-ribose) polymerase family member 10 JBrowse link 8 143,977,158 143,986,460 RGD:2290271
G PARP16 poly(ADP-ribose) polymerase family member 16 JBrowse link 15 65,231,691 65,286,891 RGD:2290271
G PARP9 poly(ADP-ribose) polymerase family member 9 JBrowse link 3 122,527,924 122,564,784 RGD:2290271
G PTGIS prostaglandin I2 synthase JBrowse link 20 49,503,874 49,568,137 RGD:2290271
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:2290271
G RNLS renalase, FAD dependent amine oxidase JBrowse link 10 88,176,052 88,584,480 RGD:2290271
G SLC22A13 solute carrier family 22 member 13 JBrowse link 3 38,265,812 38,278,757 RGD:2290271
G SLC5A8 solute carrier family 5 member 8 JBrowse link 12 101,155,493 101,210,238 RGD:2290271
NAD biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AFMID arylformamidase JBrowse link 17 78,185,102 78,207,702 RGD:2290271
G ASPDH aspartate dehydrogenase domain containing JBrowse link 19 50,511,600 50,514,684 RGD:2290271
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 2 42,767,087 42,801,002 RGD:2290271
G KYNU kynureninase JBrowse link 2 142,877,664 143,055,833 RGD:2290271
G NADSYN1 NAD synthetase 1 JBrowse link 11 71,453,203 71,501,816 RGD:2290271
G NAMPT nicotinamide phosphoribosyltransferase JBrowse link 7 106,248,298 106,284,983 RGD:2290271
G NAPRT nicotinate phosphoribosyltransferase JBrowse link 8 143,574,585 143,578,349 RGD:2290271
G NMNAT1 nicotinamide nucleotide adenylyltransferase 1 JBrowse link 1 9,942,923 9,996,884 RGD:2290271
G NMNAT2 nicotinamide nucleotide adenylyltransferase 2 JBrowse link 1 183,248,237 183,418,380 RGD:2290271
G NMNAT3 nicotinamide nucleotide adenylyltransferase 3 JBrowse link 3 139,560,180 139,678,050 RGD:2290271
G NMRK1 nicotinamide riboside kinase 1 JBrowse link 9 75,060,577 75,088,319 RGD:2290271
G NMRK2 nicotinamide riboside kinase 2 JBrowse link 19 3,933,103 3,942,416 RGD:2290271
G QPRT quinolinate phosphoribosyltransferase JBrowse link 16 29,670,588 29,698,699 RGD:2290271
NAD catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NUDT12 nudix hydrolase 12 JBrowse link 5 103,548,855 103,562,805 RGD:2290271
G NUDT17 nudix hydrolase 17 JBrowse link 1 145,844,985 145,848,954 RGD:2290271
G SARM1 sterile alpha and TIR motif containing 1 JBrowse link 17 28,371,694 28,404,049 RGD:2290271
G TIGD7 tigger transposable element derived 7 JBrowse link 16 3,298,808 3,305,430 RGD:9068941
NAD salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NAPRT nicotinate phosphoribosyltransferase JBrowse link 8 143,574,585 143,578,349 RGD:2290271
NADP biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G G6PD glucose-6-phosphate dehydrogenase JBrowse link X 154,531,390 154,547,569 RGD:9068941
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 15 90,083,045 90,102,468 RGD:2290271
G NADK NAD kinase JBrowse link 1 1,751,232 1,780,509 RGD:2290271
G NADK2 NAD kinase 2, mitochondrial JBrowse link 5 36,192,589 36,242,279 RGD:2290271
NADP catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NUDT12 nudix hydrolase 12 JBrowse link 5 103,548,855 103,562,805 RGD:2290271
G NUDT13 nudix hydrolase 13 JBrowse link 10 73,110,375 73,131,828 RGD:2290271
G NUDT17 nudix hydrolase 17 JBrowse link 1 145,844,985 145,848,954 RGD:2290271
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACMSD aminocarboxymuconate semialdehyde decarboxylase JBrowse link 2 134,838,319 134,902,906 RGD:2290271
nicotinamide nucleotide metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NAXE NAD(P)HX epimerase JBrowse link 1 156,591,776 156,599,818 RGD:2290271
nicotinamide riboside catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MTAP methylthioadenosine phosphorylase JBrowse link 9 21,802,636 21,867,081 RGD:2290271
G PNP purine nucleoside phosphorylase JBrowse link 14 20,469,406 20,477,089 RGD:2290271
picolinic acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACMSD aminocarboxymuconate semialdehyde decarboxylase JBrowse link 2 134,838,319 134,902,906 RGD:2290271
pyridoxal 5'-phosphate salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDXK pyridoxal kinase JBrowse link 21 43,737,000 43,738,097 RGD:2290271
G PDXK pyridoxal kinase JBrowse link 21 43,719,129 43,762,299 RGD:2290271
pyridoxal phosphate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDXK pyridoxal kinase JBrowse link 21 43,737,000 43,738,097 RGD:9068941
G PNPO pyridoxamine 5'-phosphate oxidase JBrowse link 17 47,941,524 47,949,308 RGD:2290271
pyridoxal phosphate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDXP pyridoxal phosphatase JBrowse link 22 37,658,723 37,666,932 RGD:2290271
pyridoxine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PNPO pyridoxamine 5'-phosphate oxidase JBrowse link 17 47,941,524 47,949,308 RGD:2290271
G PSAT1 phosphoserine aminotransferase 1 JBrowse link 9 78,297,125 78,330,093 RGD:2290271
quinolinate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 2 42,767,087 42,801,002 RGD:2290271
G HTT huntingtin JBrowse link 4 3,074,681 3,243,960 RGD:9068941
G KMO kynurenine 3-monooxygenase JBrowse link 1 241,531,883 241,595,642 RGD:2290271
G KYNU kynureninase JBrowse link 2 142,877,664 143,055,833 RGD:2290271
quinolinate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G QPRT quinolinate phosphoribosyltransferase JBrowse link 16 29,670,588 29,698,699 RGD:2290271
quinolinate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 2 42,767,087 42,801,002 RGD:2290271
G QPRT quinolinate phosphoribosyltransferase JBrowse link 16 29,670,588 29,698,699 RGD:9068941
regulation of 'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACMSD aminocarboxymuconate semialdehyde decarboxylase JBrowse link 2 134,838,319 134,902,906 RGD:2290271
vitamin B6 metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AOX1 aldehyde oxidase 1 JBrowse link 2 200,585,952 200,677,064 RGD:2290271
G PDXK pyridoxal kinase JBrowse link 21 43,719,129 43,762,299 RGD:2290271
G PNPO pyridoxamine 5'-phosphate oxidase JBrowse link 17 47,941,524 47,949,308 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18539
    metabolic process 12198
      nitrogen compound metabolic process 10400
        cellular nitrogen compound metabolic process 6676
          pyridine-containing compound metabolic process 46
            2,5-dihydroxypyridine metabolic process + 0
            aspyridone A metabolic process + 0
            aspyridone B metabolic process + 0
            nicotinamide metabolic process + 0
            nicotinate metabolic process + 0
            picolinic acid metabolic process + 1
            pyridine metabolic process + 0
            pyridine nucleoside metabolic process + 2
            pyridine nucleotide metabolic process + 37
            pyridine-containing compound biosynthetic process + 38
            pyridine-containing compound catabolic process + 9
            quinolinate metabolic process + 6
            vitamin B6 metabolic process + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.