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ONTOLOGY REPORT - ANNOTATIONS


Term:ER membrane protein complex
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Accession:GO:0072546 term browser browse the term
Definition:A transmembrane protein complex located in the ER that is involved in ER-mitochondrial membrane tethering, which is required to facilitate lipid transfer from the ER to the mitochondrial membrane. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6.
Synonyms:exact_synonym: EMC;   endoplasmic reticulum membrane protein complex


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ER membrane protein complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Emc1 ER membrane protein complex subunit 1 JBrowse link 5 157,820,908 157,846,226 RGD:1624291
RGD:13792537
G Emc10 ER membrane protein complex subunit 10 JBrowse link 1 100,495,112 100,501,468 RGD:1624291
RGD:13792537
RGD:1600115
G Emc2 ER membrane protein complex subunit 2 JBrowse link 7 82,338,639 82,377,389 RGD:1624291
RGD:1600115
RGD:13792537
G Emc3 ER membrane protein complex subunit 3 JBrowse link 4 145,471,466 145,487,375 RGD:1624291
RGD:13792537
RGD:1600115
G Emc4 ER membrane protein complex subunit 4 JBrowse link 3 103,852,139 103,857,172 RGD:1624291
RGD:13792537
G Emc6 ER membrane protein complex subunit 6 JBrowse link 10 59,741,772 59,743,338 RGD:1624291
RGD:13792537
G Emc7 ER membrane protein complex subunit 7 JBrowse link 3 103,945,276 103,955,970 RGD:1624291
RGD:13792537
G Emc8 ER membrane protein complex subunit 8 JBrowse link 19 54,235,949 54,245,810 RGD:1624291
RGD:13792537
RGD:1600115
G Emc9 ER membrane protein complex subunit 9 JBrowse link 15 34,258,940 34,263,156 RGD:1624291
RGD:13792537
RGD:1600115
G Mmgt1 membrane magnesium transporter 1 JBrowse link X 158,966,694 158,978,995 RGD:1624291
RGD:1600115
RGD:13792537
G Mmgt2 membrane magnesium transporter 2 JBrowse link 10 48,986,163 48,989,596 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19951
    protein-containing complex 5828
      membrane protein complex 1228
        ER membrane protein complex 11
Path 2
Term Annotations click to browse term
  cellular_component 19951
    cellular anatomical entity 19598
      organelle 12670
        membrane-bounded organelle 10978
          organelle membrane 2715
            intrinsic component of organelle membrane 395
              integral component of organelle membrane 361
                integral component of endoplasmic reticulum membrane 144
                  ER membrane protein complex 11
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.