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ONTOLOGY REPORT - ANNOTATIONS


Term:IRES-dependent viral translational initiation
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Accession:GO:0075522 term browser browse the term
Definition:Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation.
Synonyms:xref: VZ:867 "Viral initiation of translation: IRES and DLP"


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IRES-dependent viral translational initiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Denr density regulated reinitiation and release factor ISO (PMID:20713520) RGD PMID:20713520 NCBI chr12:38,095,717...38,117,758
Ensembl chr12:38,096,034...38,116,919
JBrowse link
G Eif2d eukaryotic translation initiation factor 2D ISO (PMID:20713520) RGD PMID:20713520 NCBI chr13:47,935,138...47,958,459
Ensembl chr13:47,935,163...47,954,090
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A ISO (PMID:23766293), (PMID:24357634), (PMID:9573242) RGD PMID:9573242, PMID:23766293, PMID:24357634 NCBI chr 1:282,139,809...282,170,017
Ensembl chr 1:282,139,823...282,170,017
JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B ISO (PMID:9573242) RGD PMID:9573242 NCBI chr12:16,285,730...16,310,190
Ensembl chr12:16,285,733...16,310,190
JBrowse link
G Eif3d eukaryotic translation initiation factor 3, subunit D ISO (PMID:9573242) RGD PMID:9573242 NCBI chr 7:119,188,189...119,200,578
Ensembl chr 7:119,188,185...119,200,623
JBrowse link
G Eif3f eukaryotic translation initiation factor 3, subunit F ISO (PMID:9573242) RGD PMID:9573242 NCBI chr 1:173,532,826...173,541,806
Ensembl chr 1:173,532,803...173,541,847
JBrowse link
G Mcts1 MCTS1, re-initiation and release factor ISO (PMID:20713520) RGD PMID:20713520 NCBI chr  X:124,894,269...124,906,129
Ensembl chr  X:124,894,466...124,906,162
JBrowse link
G Pcbp2 poly(rC) binding protein 2 ISO (PMID:12414943) RGD PMID:12414943 NCBI chr 7:144,077,901...144,103,723
Ensembl chr 7:144,078,496...144,101,893
JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 ISO
IEA
(PMID:21518806)
GO_REF:0000107
RGD
Ensembl
PMID:21518806 GO_REF:0000107 NCBI chr 7:12,663,965...12,673,723
Ensembl chr 7:12,663,965...12,673,718
JBrowse link
G Ssb small RNA binding exonuclease protection factor La ISO (PMID:12384597) RGD PMID:12384597 NCBI chr 3:56,092,425...56,102,008
Ensembl chr 3:56,092,501...56,102,001
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    interspecies interaction between organisms 1917
      symbiotic process 400
        viral process 334
          IRES-dependent viral translational initiation 10
Path 2
Term Annotations click to browse term
  biological_process 20027
    interspecies interaction between organisms 1917
      symbiotic process 400
        viral process 334
          viral gene expression 70
            viral translation 15
              IRES-dependent viral translational initiation 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.