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ONTOLOGY REPORT - ANNOTATIONS


Term:viral translational termination-reinitiation
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Accession:GO:0075525 term browser browse the term
Definition:A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF.
Comment:This term is intended to annotate gene products involved in the process of viral translational termination-reinitiation, not viral proteins produced by this translation process.
Synonyms:exact_synonym: termination reinitiation involved in viral translation;   viral translation involving termination re-initiation;   viral translation involving termination-reinitiation;   viral translation involving translational stop-start
 xref: VZ:858 "RNA termination-reinitiation"


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viral translational termination-reinitiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif3a eukaryotic translation initiation factor 3, subunit A ISO (PMID:21347434) RGD PMID:21347434 NCBI chr 1:282,139,809...282,170,017
Ensembl chr 1:282,139,823...282,170,017
JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B ISO (PMID:21347434) RGD PMID:21347434 NCBI chr12:16,285,730...16,310,190
Ensembl chr12:16,285,733...16,310,190
JBrowse link
G Eif3d eukaryotic translation initiation factor 3, subunit D ISO (PMID:21347434) RGD PMID:21347434 NCBI chr 7:119,188,189...119,200,578
Ensembl chr 7:119,188,185...119,200,623
JBrowse link
G Eif3g eukaryotic translation initiation factor 3, subunit G ISO (PMID:21347434) RGD PMID:21347434 NCBI chr 8:21,911,632...21,915,664
Ensembl chr 8:21,911,625...21,915,716
JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L ISO (PMID:21347434) RGD PMID:21347434 NCBI chr 7:120,320,547...120,331,596
Ensembl chr 7:120,320,547...120,331,595
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 20027
    interspecies interaction between organisms 1917
      symbiotic process 400
        viral process 334
          viral translational termination-reinitiation 5
Path 2
Term Annotations click to browse term
  biological_process 20027
    interspecies interaction between organisms 1917
      symbiotic process 400
        viral process 334
          viral gene expression 70
            viral translation 15
              viral translational termination-reinitiation 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.