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ONTOLOGY REPORT - ANNOTATIONS


Term:lytic vacuole organization
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Accession:GO:0080171 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
Synonyms:exact_synonym: lytic vacuole organisation
 narrow_synonym: lytic vacuolar assembly
 related_synonym: lytic vacuole biogenesis;   lytic vacuole organization and biogenesis


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lysosomal lumen acidification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp6ap2 ATPase H+ transporting accessory protein 2 JBrowse link X 11,137,889 11,164,854 RGD:1624291
RGD:1600115
G Ccdc115 coiled-coil domain containing 115 JBrowse link 9 37,774,876 37,778,839 RGD:1624291
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin JBrowse link 1 197,986,384 197,999,726 RGD:1624291
RGD:13792537
RGD:1600115
G Cln5 CLN5, intracellular trafficking protein JBrowse link 15 93,634,815 93,644,146 RGD:1624291
G Cln6 CLN6, transmembrane ER protein JBrowse link 8 67,733,215 67,748,170 RGD:1624291
G Grn granulin precursor JBrowse link 10 90,377,103 90,383,207 RGD:1600115
RGD:1624291
G Ppt1 palmitoyl-protein thioesterase 1 JBrowse link 5 140,538,260 140,558,163 RGD:1624291
RGD:8553248
G Snapin SNAP-associated protein JBrowse link 2 189,878,159 189,880,743 RGD:1624291
G Tmem199 transmembrane protein 199 JBrowse link 10 65,775,721 65,780,293 RGD:1624291
RGD:1600115
lysosomal lumen pH elevation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin JBrowse link 1 197,986,384 197,999,726 RGD:1624291
RGD:1600115
lysosomal membrane organization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arf1 ADP-ribosylation factor 1 JBrowse link 10 45,562,700 45,579,214 RGD:9684948
lysosome organization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07008608.1 RGD:13792537
G AABR07019209.2 RGD:13792537
G AABR07026291.1 RGD:1600115
G AABR07028902.1 RGD:1600115
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:1624291
G Acp2 acid phosphatase 2, lysosomal JBrowse link 3 80,020,346 80,030,365 RGD:1600115
RGD:1624291
G Aktip AKT interacting protein JBrowse link 19 17,290,048 17,300,054 RGD:1624291
RGD:1600115
G Ap3b1 adaptor related protein complex 3 subunit beta 1 JBrowse link 2 24,022,815 24,227,522 RGD:1624291
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:1624291
G Chmp5 charged multivesicular body protein 5 JBrowse link 5 57,267,312 57,284,455 RGD:1624291
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin JBrowse link 1 197,986,384 197,999,726 RGD:1624291
RGD:13792537
G Cln5 CLN5, intracellular trafficking protein JBrowse link 15 93,634,815 93,644,146 RGD:1624291
G Cln6 CLN6, transmembrane ER protein JBrowse link 8 67,733,215 67,748,170 RGD:1624291
RGD:13792537
G Cln8 CLN8, transmembrane ER and ERGIC protein JBrowse link 16 79,828,321 79,838,212 RGD:1624291
G Clvs1 clavesin 1 JBrowse link 5 22,380,318 22,580,391 RGD:1600115
RGD:13792537
RGD:8553526
G Clvs2 clavesin 2 JBrowse link 1 25,173,089 25,217,625 RGD:8553526
RGD:13792537
G Fam160a2 family with sequence similarity 160, member A2 JBrowse link 1 170,216,505 170,238,898 RGD:1624291
RGD:1600115
G Gaa glucosidase, alpha, acid JBrowse link 10 108,395,873 108,412,999 RGD:1624291
RGD:1600115
G Gba glucosylceramidase beta JBrowse link 2 188,511,781 188,522,602 RGD:1624291
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta JBrowse link 7 28,956,363 29,023,232 RGD:1624291
G Grn granulin precursor JBrowse link 10 90,377,103 90,383,207 RGD:1600115
RGD:1624291
G Hexa hexosaminidase subunit alpha JBrowse link 8 64,325,435 64,350,775 RGD:1624291
G Hexb hexosaminidase subunit beta JBrowse link 2 27,983,925 28,003,260 RGD:1624291
RGD:1600115
G Hook1 hook microtubule-tethering protein 1 JBrowse link 5 114,940,053 115,000,691 RGD:1624291
G Hook2 hook microtubule-tethering protein 2 JBrowse link 19 26,106,713 26,119,353 RGD:1624291
G Hook3 hook microtubule-tethering protein 3 JBrowse link 16 70,710,347 70,818,789 RGD:1624291
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 JBrowse link 1 261,989,178 262,015,282 RGD:1624291
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 JBrowse link 12 50,285,239 50,315,893 RGD:1624291
G Idua alpha-L-iduronidase JBrowse link 14 2,041,828 2,056,762 RGD:1624291
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 JBrowse link 1 166,991,474 166,997,045 RGD:1624291
RGD:1600115
G LOC100361543 RhoA activator C11orf59-like JBrowse link X 37,261,428 37,262,470 RGD:1600115
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
G Lyst lysosomal trafficking regulator JBrowse link 17 90,323,055 90,522,091 RGD:1624291
G Mbtps1 membrane-bound transcription factor peptidase, site 1 JBrowse link 19 52,146,507 52,206,310 RGD:1624291
RGD:1600115
G Mfsd8 major facilitator superfamily domain containing 8 JBrowse link 2 127,706,618 127,784,129 RGD:1624291
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:1624291
RGD:1600115
G Myo7a myosin VIIA JBrowse link 1 163,001,313 163,071,545 RGD:1624291
RGD:1600115
G Naglu N-acetyl-alpha-glucosaminidase JBrowse link 10 88,979,363 88,986,879 RGD:1624291
G Ppt1 palmitoyl-protein thioesterase 1 JBrowse link 5 140,538,260 140,558,163 RGD:1624291
G Snapin SNAP-associated protein JBrowse link 2 189,878,159 189,880,743 RGD:1624291
RGD:13792537
G Spg11 SPG11 vesicle trafficking associated, spatacsin JBrowse link 3 113,999,600 114,064,438 RGD:1624291
G Tfeb transcription factor EB JBrowse link 9 15,208,141 15,264,101 RGD:1624291
G Tmem106b transmembrane protein 106B JBrowse link 4 39,517,679 39,534,491 RGD:1624291
RGD:13792537
G Tpcn2 two pore segment channel 2 JBrowse link 1 218,419,182 218,448,902 RGD:1624291
G Tpp1 tripeptidyl peptidase 1 JBrowse link 1 170,588,036 170,594,159 RGD:1624291
RGD:1600115
G Vps18 VPS18 core subunit of CORVET and HOPS complexes JBrowse link 3 111,097,352 111,108,206 RGD:1624291
RGD:13792537
G Vps35 VPS35 retromer complex component JBrowse link 19 27,464,937 27,500,636 RGD:1624291
G Washc5 WASH complex subunit 5 JBrowse link 7 99,625,379 99,677,237 RGD:1624291
G Zkscan3 zinc finger with KRAB and SCAN domains 3 JBrowse link 17 45,247,724 45,263,422 RGD:1624291
negative regulation of lysosome organization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:11561937
phagolysosome assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Coro1a coronin 1A JBrowse link 1 198,123,883 198,128,890 RGD:1624291
G Myo7a myosin VIIA JBrowse link 1 163,001,313 163,071,545 RGD:1624291
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1624291
G Srpx sushi-repeat-containing protein, X-linked JBrowse link X 14,146,618 14,220,756 RGD:1624291
phagolysosome assembly involved in apoptotic cell clearance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rab14 RAB14, member RAS oncogene family JBrowse link 3 14,373,270 14,395,357 RGD:13792537
phagosome-lysosome docking term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin JBrowse link 1 197,986,384 197,999,726 RGD:1624291
phagosome-lysosome fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07037545.1 RGD:13792537
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin JBrowse link 1 197,986,384 197,999,726 RGD:1624291
G Pla2g5 phospholipase A2, group V JBrowse link 5 157,247,601 157,268,968 RGD:1600115
RGD:1624291
G Rab20 RAB20, member RAS oncogene family JBrowse link 16 83,358,116 83,382,326 RGD:1624291
G Rab34 RAB34, member RAS oncogene family JBrowse link 10 65,448,111 65,452,178 RGD:1624291
RGD:13792537
RGD:1600115
G Rab39a RAB39A, member RAS oncogene family JBrowse link 8 58,275,984 58,292,995 RGD:1624291
G Rab7a RAB7A, member RAS oncogene family JBrowse link 4 119,910,461 119,963,065 RGD:1624291
RGD:13792537
RGD:1600115
G Rab7b Rab7b, member RAS oncogene family JBrowse link 13 48,456,143 48,483,714 RGD:13792537
G Syt7 synaptotagmin 7 JBrowse link 1 226,435,816 226,498,008 RGD:1624291
RGD:1600115
G Tmem175 transmembrane protein 175 JBrowse link 14 2,083,745 2,100,006 RGD:1624291
RGD:1600115
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Spg11 SPG11 vesicle trafficking associated, spatacsin JBrowse link 3 113,999,600 114,064,438 RGD:1624291
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:10059368
G Mt3 metallothionein 3 JBrowse link 19 11,324,708 11,326,112 RGD:1624291
RGD:1600115
positive regulation of lysosome organization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grn granulin precursor JBrowse link 10 90,377,103 90,383,207 RGD:1600115
RGD:1624291
regulation of lysosomal lumen pH term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC681325 hypothetical protein LOC681325 JBrowse link X 80,359,555 80,363,168 RGD:13792537
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
G RGD1565785 similar to chromosome X open reading frame 21 JBrowse link X 54,390,733 54,409,466 RGD:1624291
RGD:13792537
G Tmem165 transmembrane protein 165 JBrowse link 14 34,503,037 34,528,262 RGD:1624291
RGD:1600115
G Tmem175 transmembrane protein 175 JBrowse link 14 2,083,745 2,100,006 RGD:1624291
RGD:1600115
G Vps33a VPS33A core subunit of CORVET and HOPS complexes JBrowse link 12 38,459,816 38,482,903 RGD:1624291
RGD:1600115
regulation of lysosomal membrane permeability term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Laptm4b lysosomal protein transmembrane 4 beta JBrowse link 7 72,924,911 72,968,099 RGD:1624291
RGD:1600115
regulation of lysosome organization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Laptm4b lysosomal protein transmembrane 4 beta JBrowse link 7 72,924,911 72,968,099 RGD:1624291
RGD:1600115
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291

Term paths to the root
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Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      cellular component organization or biogenesis 6706
        cellular component organization 6456
          organelle organization 4029
            vacuole organization 194
              lytic vacuole organization 74
                lysosome organization + 74
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.