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ONTOLOGY REPORT - ANNOTATIONS


Term:lytic vacuole organization
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Accession:GO:0080171 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
Synonyms:exact_synonym: lytic vacuole organisation
 narrow_synonym: lytic vacuolar assembly
 related_synonym: lytic vacuole biogenesis;   lytic vacuole organization and biogenesis


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lysosomal lumen acidification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 ISO
ISS
(PMID:32276428)
GO_REF:0000024
RGD
UniProt
PMID:32276428 GO_REF:0000024 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Ccdc115 coiled-coil domain containing 115 ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:37,774,876...37,778,839
Ensembl chr 9:37,775,311...37,779,967
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO
IBA
ISS
(PMID:11722572)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:11722572, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Cln5 CLN5, intracellular trafficking protein ISO (PMID:11722572) RGD PMID:11722572 NCBI chr15:93,634,815...93,644,146 JBrowse link
G Cln6 CLN6, transmembrane ER protein ISO (PMID:11722572) RGD PMID:11722572 NCBI chr 8:67,733,215...67,748,170
Ensembl chr 8:67,733,215...67,748,172
JBrowse link
G Grn granulin precursor ISS
ISO
IEA
GO_REF:0000024
(PMID:28073925)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28073925 GO_REF:0000024, GO_REF:0000107 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 ISO
ISS
(PMID:11722572)
PMID:8895569
RGD PMID:11722572, PMID:8895569 RGD:8553248 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Snapin SNAP-associated protein ISO MGI:MGI:3608768 (MGI:MGI:4879078|PMID:20920792) RGD PMID:20920792 MGI:MGI:4879078 NCBI chr 2:189,878,159...189,880,743
Ensembl chr 2:189,878,168...189,880,743
JBrowse link
G Tmem199 transmembrane protein 199 ISO
ISS
(PMID:28296633)
GO_REF:0000024
RGD
UniProt
PMID:28296633 GO_REF:0000024 NCBI chr10:65,775,721...65,780,293
Ensembl chr10:65,775,715...65,780,349
JBrowse link
G Tmem9 transmembrane protein 9 ISO (PMID:30374053) RGD PMID:30374053 NCBI chr13:52,854,031...52,871,300
Ensembl chr13:52,854,031...52,871,297
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO
ISS
(PMID:10924275)
GO_REF:0000024
RGD
UniProt
PMID:10924275 GO_REF:0000024 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ADP-ribosylation factor 1 IDA RGD PMID:9538255 RGD:9684948 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07008608.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:66,600,151...66,608,324 JBrowse link
G AABR07019209.2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr15:93,634,820...93,639,250 JBrowse link
G AABR07028902.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr17:90,370,882...90,522,091 JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 ISO (PMID:15163665) RGD PMID:15163665 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Acp2 acid phosphatase 2, lysosomal IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
MGI:MGI:2180084|MGI:MGI:3574793 (MGI:MGI:3522374|PMID:15604265), (MGI:MGI:894905|PMID:9228031)
Ensembl
RGD
PMID:9228031, PMID:15604265, PMID:21873635 GO_REF:0000107, MGI:MGI:3522374, MGI:MGI:894905, RGD:13792537 NCBI chr 3:80,020,346...80,030,365
Ensembl chr 3:80,021,440...80,030,363
JBrowse link
G Acp3 acid phosphatase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:112,838,574...112,884,062
Ensembl chr 8:112,834,707...112,884,077
JBrowse link
G Acp4 acid phosphatase 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:100,226,311...100,234,536
Ensembl chr 1:100,227,157...100,234,040
JBrowse link
G Aktip AKT interacting protein ISO
ISS
(PMID:18799622)
GO_REF:0000024
RGD
UniProt
PMID:18799622 GO_REF:0000024 NCBI chr19:17,290,048...17,300,054
Ensembl chr19:17,290,178...17,300,050
JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 ISO (MGI:MGI:1330543|PMID:9931340), (MGI:MGI:6415001|PMID:30786955) RGD PMID:9931340, PMID:30786955 MGI:MGI:1330543, MGI:MGI:6415001 NCBI chr 2:24,022,815...24,227,522
Ensembl chr 2:24,024,791...24,226,224
JBrowse link
G Becn1 beclin 1 ISO MGI:MGI:2683696 (MGI:MGI:3801567|PMID:18497889) RGD PMID:18497889 MGI:MGI:3801567 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Chmp5 charged multivesicular body protein 5 ISO MGI:MGI:3626293 (MGI:MGI:3622513|PMID:16567502) RGD PMID:16567502 MGI:MGI:3622513 NCBI chr 5:57,267,312...57,284,455
Ensembl chr 5:57,267,312...57,284,448
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO
IBA
MGI:MGI:1933976|MGI:MGI:2388887|MGI:MGI:3623134 (MGI:MGI:1337525|PMID:10191119), (MGI:MGI:1343910|PMID:10440905), (MGI:MGI:1346962|PMID:10527801), (MGI:MGI:3527911|PMID:15588329)
PMID:21873635
RGD PMID:10191119, PMID:10440905, PMID:10527801, PMID:15588329, PMID:21873635 MGI:MGI:1337525, MGI:MGI:1343910, MGI:MGI:1346962, MGI:MGI:3527911, RGD:13792537 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Cln5 CLN5, intracellular trafficking protein ISO MGI:MGI:3521802 (MGI:MGI:3512689|PMID:15459177) RGD PMID:15459177 MGI:MGI:3512689 NCBI chr15:93,634,815...93,644,146 JBrowse link
G Cln6 CLN6, transmembrane ER protein ISO
IBA
MGI:MGI:2159328 (MGI:MGI:1203267|PMID:9600738), (MGI:MGI:5751614|PMID:26681805)
PMID:21873635
RGD PMID:9600738, PMID:26681805, PMID:21873635 MGI:MGI:1203267, MGI:MGI:5751614, RGD:13792537 NCBI chr 8:67,733,215...67,748,170
Ensembl chr 8:67,733,215...67,748,172
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein ISO MGI:MGI:1856959 (MGI:MGI:1333651|PMID:10087069), (MGI:MGI:65559|PMID:8144516), (MGI:MGI:66707|PMID:8160780), (MGI:MGI:71226|PMID:7613514) RGD PMID:7613514, PMID:8144516, PMID:8160780, PMID:10087069 MGI:MGI:1333651, MGI:MGI:65559, MGI:MGI:66707, MGI:MGI:71226 NCBI chr16:79,828,321...79,838,212
Ensembl chr16:79,828,324...79,838,212
JBrowse link
G Clvs1 clavesin 1 IEA
IBA
IMP
GO_REF:0000002
PMID:21873635
PMID:19651769
InterPro PMID:21873635, PMID:19651769 GO_REF:0000002, RGD:13792537, RGD:8553526 NCBI chr 5:22,380,318...22,580,391
Ensembl chr 5:22,380,334...22,578,297
JBrowse link
G Clvs2 clavesin 2 IMP
IBA
PMID:19651769
PMID:21873635
UniProt
GO_Central
PMID:19651769, PMID:21873635 RGD:8553526, RGD:13792537 NCBI chr 1:25,173,089...25,217,625
Ensembl chr 1:25,173,242...25,296,927
JBrowse link
G Fam160a2 family with sequence similarity 160, member A2 ISO
ISS
(PMID:18799622)
GO_REF:0000024
RGD
UniProt
PMID:18799622 GO_REF:0000024 NCBI chr 1:170,216,505...170,238,898
Ensembl chr 1:170,212,817...170,238,890
JBrowse link
G Gaa glucosidase, alpha, acid ISO
IEA
(PMID:7717400)
MGI:MGI:2148550|MGI:MGI:2179961 (MGI:MGI:1195358|PMID:9384603), (MGI:MGI:1275872|PMID:9668092), (MGI:MGI:1346721|PMID:10547605), (MGI:MGI:2136118|PMID:11328962), (MGI:MGI:3618942|PMID:15169761), (MGI:MGI:3664400|PMID:12115977)
GO_REF:0000107
RGD
Ensembl
PMID:7717400, PMID:9384603, PMID:9668092, PMID:10547605, PMID:11328962, PMID:12115977, PMID:15169761 GO_REF:0000107, MGI:MGI:1195358, MGI:MGI:1275872, MGI:MGI:1346721, MGI:MGI:2136118, MGI:MGI:3618942, MGI:MGI:3664400 NCBI chr10:108,395,873...108,412,999
Ensembl chr10:108,395,860...108,413,059
JBrowse link
G Gba glucosylceramidase beta ISO (PMID:27378698)
(MGI:MGI:5817293|PMID:27378698)
RGD PMID:27378698 MGI:MGI:5817293 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta ISO (PMID:21719679) RGD PMID:21719679 NCBI chr 7:28,956,363...29,023,232
Ensembl chr 7:28,956,512...29,022,868
JBrowse link
G Grn granulin precursor ISS
ISO
GO_REF:0000024
(MGI:MGI:6274951|PMID:27789271)
UniProt
RGD
PMID:27789271 GO_REF:0000024, MGI:MGI:6274951 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Hexa hexosaminidase subunit alpha ISO MGI:MGI:1857181|MGI:MGI:2429698|MGI:MGI:3581540|MGI:MGI:96074 (MGI:MGI:1097747|PMID:9302266), (MGI:MGI:1271008|PMID:9645704), (MGI:MGI:1352198|PMID:10591619), (MGI:MGI:3033296|PMID:14972652), (MGI:MGI:69059|PMID:7937929), (MGI:MGI:77946|PMID:8747922), (MGI:MGI:83770|PMID:8896570), (MGI:MGI:86923|PMID:9103204), (MGI:MGI:894634|PMID:9184660) RGD PMID:7937929, PMID:8747922, PMID:8896570, PMID:9103204, PMID:9184660, PMID:9302266, PMID:9645704, PMID:10591619, PMID:14972652 MGI:MGI:1097747, MGI:MGI:1271008, MGI:MGI:1352198, MGI:MGI:3033296, MGI:MGI:69059, MGI:MGI:77946, MGI:MGI:83770, MGI:MGI:86923, MGI:MGI:894634 NCBI chr 8:64,325,435...64,350,775
Ensembl chr 8:64,325,435...64,350,773
JBrowse link
G Hexb hexosaminidase subunit beta ISO
IEA
MGI:MGI:2429701|MGI:MGI:96073 (MGI:MGI:1271008|PMID:9645704), (MGI:MGI:78473|PMID:8789434), (MGI:MGI:83770|PMID:8896570), (MGI:MGI:894634|PMID:9184660)
GO_REF:0000107
RGD
Ensembl
PMID:8789434, PMID:8896570, PMID:9184660, PMID:9645704 GO_REF:0000107, MGI:MGI:1271008, MGI:MGI:78473, MGI:MGI:83770, MGI:MGI:894634 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hook1 hook microtubule-tethering protein 1 ISO (PMID:18799622) RGD PMID:18799622 NCBI chr 5:114,940,053...115,000,691
Ensembl chr 5:114,940,053...115,000,691
JBrowse link
G Hook2 hook microtubule-tethering protein 2 ISO (PMID:18799622) RGD PMID:18799622 NCBI chr19:26,106,713...26,119,353
Ensembl chr19:26,106,838...26,119,352
JBrowse link
G Hook3 hook microtubule-tethering protein 3 ISO (PMID:18799622) RGD PMID:18799622 NCBI chr16:70,710,347...70,818,789 JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 ISO (MGI:MGI:6415001|PMID:30786955) RGD PMID:30786955 MGI:MGI:6415001 NCBI chr 1:261,989,178...262,015,282
Ensembl chr 1:261,989,178...262,015,153
JBrowse link
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 ISO (PMID:12663659) RGD PMID:12663659 NCBI chr12:50,285,239...50,315,893
Ensembl chr12:50,285,278...50,314,406
JBrowse link
G Idua alpha-L-iduronidase ISO MGI:MGI:2176236|MGI:MGI:4415188 (MGI:MGI:4414887|PMID:19751987), (MGI:MGI:86916|PMID:9097952) RGD PMID:9097952, PMID:19751987 MGI:MGI:4414887, MGI:MGI:86916 NCBI chr14:2,041,828...2,056,762
Ensembl chr14:2,042,411...2,056,762
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 ISO
ISS
(MGI:MGI:4887551|PMID:19177150)
GO_REF:0000024
RGD
UniProt
PMID:19177150 GO_REF:0000024, MGI:MGI:4887551 NCBI chr 1:166,991,474...166,997,045
Ensembl chr 1:166,991,474...166,997,045
JBrowse link
G LOC100361543 RhoA activator C11orf59-like ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:37,261,428...37,262,470
Ensembl chr 1:166,991,474...166,997,045
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO (PMID:25416817) RGD PMID:25416817 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Lyst lysosomal trafficking regulator ISO MGI:MGI:1855968|MGI:MGI:1855969 (MGI:MGI:1099544|PMID:9368050), (MGI:MGI:53816|PMID:4697831), (MGI:MGI:53992|PMID:1113502), (MGI:MGI:55104|PMID:6170520), (MGI:MGI:56449|PMID:4031470) RGD PMID:1113502, PMID:4031470, PMID:4697831, PMID:6170520, PMID:9368050 MGI:MGI:1099544, MGI:MGI:53816, MGI:MGI:53992, MGI:MGI:55104, MGI:MGI:56449 NCBI chr17:90,323,055...90,522,091 JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 ISO
ISS
(PMID:21719679)
GO_REF:0000024
RGD
UniProt
PMID:21719679 GO_REF:0000024 NCBI chr19:52,146,507...52,206,310
Ensembl chr19:52,146,808...52,206,310
JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 ISO MGI:MGI:4456699 (MGI:MGI:5575728|PMID:24423645), (MGI:MGI:5751614|PMID:26681805) RGD PMID:24423645, PMID:26681805 MGI:MGI:5575728, MGI:MGI:5751614 NCBI chr 2:127,706,618...127,784,129
Ensembl chr 2:127,699,761...127,781,003
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO
ISS
(PMID:22692423)
GO_REF:0000024
RGD
UniProt
PMID:22692423 GO_REF:0000024 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myo7a myosin VIIA ISO
ISS
(PMID:16001398)
GO_REF:0000024
RGD
UniProt
PMID:16001398 GO_REF:0000024 NCBI chr 1:163,001,313...163,071,545
Ensembl chr 1:163,001,875...163,071,508
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase ISO MGI:MGI:1934018 (MGI:MGI:3769195|PMID:17712420) RGD PMID:17712420 MGI:MGI:3769195 NCBI chr10:88,979,363...88,986,879
Ensembl chr10:88,979,383...88,986,867
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 ISO MGI:MGI:2176390|MGI:MGI:3527191 (MGI:MGI:3612221|PMID:16368712), (MGI:MGI:3654230|PMID:16542649) RGD PMID:16368712, PMID:16542649 MGI:MGI:3612221, MGI:MGI:3654230 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Snapin SNAP-associated protein ISO
IBA
MGI:MGI:3608768 (MGI:MGI:4879078|PMID:20920792)
PMID:21873635
RGD PMID:20920792, PMID:21873635 MGI:MGI:4879078, RGD:13792537 NCBI chr 2:189,878,159...189,880,743
Ensembl chr 2:189,878,168...189,880,743
JBrowse link
G Spg11 SPG11 vesicle trafficking associated, spatacsin ISO MGI:MGI:4377985 (MGI:MGI:5749311|PMID:26284655) RGD PMID:26284655 MGI:MGI:5749311 NCBI chr 3:113,999,600...114,064,438
Ensembl chr 3:113,999,719...114,065,170
JBrowse link
G Tfeb transcription factor EB ISO (PMID:22692423), (PMID:23434374) RGD PMID:22692423, PMID:23434374 NCBI chr 9:15,208,141...15,264,101
Ensembl chr 9:15,207,822...15,214,596
JBrowse link
G Tmem106b transmembrane protein 106B ISO
IBA
(MGI:MGI:5588048|PMID:25066864)
PMID:21873635
RGD PMID:25066864, PMID:21873635 MGI:MGI:5588048, RGD:13792537 NCBI chr 4:39,517,679...39,534,491
Ensembl chr 4:39,517,548...39,535,169
JBrowse link
G Tpcn2 two pore segment channel 2 ISO UniProtKB:Q8NHX9 (PMID:25416817) RGD PMID:25416817 NCBI chr 1:218,419,182...218,448,902
Ensembl chr 1:218,419,184...218,448,877
JBrowse link
G Tpp1 tripeptidyl peptidase 1 ISO
IEA
MGI:MGI:3521972 (MGI:MGI:3522013|PMID:15483130)
GO_REF:0000107
RGD
Ensembl
PMID:15483130 GO_REF:0000107, MGI:MGI:3522013 NCBI chr 1:170,588,036...170,594,159
Ensembl chr 1:170,588,035...170,594,168
JBrowse link
G Vps18 VPS18 core subunit of CORVET and HOPS complexes ISO
IBA
(PMID:18799622)
PMID:21873635
RGD PMID:18799622, PMID:21873635 RGD:13792537 NCBI chr 3:111,097,352...111,108,206
Ensembl chr 3:111,097,326...111,108,295
JBrowse link
G Vps35 VPS35 retromer complex component ISO (MGI:MGI:5694519|PMID:26203154) RGD PMID:26203154 MGI:MGI:5694519 NCBI chr19:27,464,937...27,500,636
Ensembl chr19:27,464,937...27,500,636
JBrowse link
G Washc5 WASH complex subunit 5 ISO MGI:MGI:6246601 (MGI:MGI:6199426|PMID:30061306) RGD PMID:30061306 MGI:MGI:6199426 NCBI chr 7:99,625,379...99,677,237
Ensembl chr 7:99,625,619...99,677,268
JBrowse link
G Zkscan3 zinc finger with KRAB and SCAN domains 3 ISO (PMID:23434374) RGD PMID:23434374 NCBI chr17:45,247,724...45,263,422
Ensembl chr17:45,247,776...45,263,418
JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 IMP RGD PMID:25561470 RGD:11561937 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
phagolysosome assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A ISO (PMID:12132654) RGD PMID:12132654 NCBI chr 1:198,123,883...198,128,890
Ensembl chr 1:198,123,884...198,128,857
JBrowse link
G Myo7a myosin VIIA ISO MGI:MGI:2155422 (MGI:MGI:2662763|PMID:12743369) RGD PMID:12743369 MGI:MGI:2662763 NCBI chr 1:163,001,313...163,071,545
Ensembl chr 1:163,001,875...163,071,508
JBrowse link
G P2rx7 purinergic receptor P2X 7 ISO MGI:MGI:3606250 (MGI:MGI:3699774|PMID:11544318) RGD PMID:11544318 MGI:MGI:3699774 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked ISO MGI:MGI:3706175 (MGI:MGI:3852261|PMID:19368996) RGD PMID:19368996 MGI:MGI:3852261 NCBI chr  X:14,146,618...14,220,756
Ensembl chr  X:14,150,038...14,220,662
JBrowse link
phagolysosome assembly involved in apoptotic cell clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab14 RAB14, member RAS oncogene family IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,373,270...14,395,357
Ensembl chr 3:14,373,275...14,395,362
JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:MGI:5698740|PMID:26450516) RGD PMID:26450516 MGI:MGI:5698740 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07037545.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:23,416,395...23,417,122 JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:MGI:5698740|PMID:26450516) RGD PMID:26450516 MGI:MGI:5698740 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing ISO
IEA
(PMID:28779020)
(MGI:MGI:6103777|PMID:28779020)
GO_REF:0000107
RGD
Ensembl
PMID:28779020 GO_REF:0000107, MGI:MGI:6103777 NCBI chr 9:71,911,744...72,005,816
Ensembl chr 9:71,915,421...72,005,838
JBrowse link
G Pla2g5 phospholipase A2, group V ISS
ISO
GO_REF:0000024
(MGI:MGI:3841317|PMID:19342668)
UniProt
RGD
PMID:19342668 GO_REF:0000024, MGI:MGI:3841317 NCBI chr 5:157,247,601...157,268,968
Ensembl chr 5:157,247,781...157,268,903
JBrowse link
G Rab20 RAB20, member RAS oncogene family ISO (PMID:21255211) RGD PMID:21255211 NCBI chr16:83,358,116...83,382,326
Ensembl chr16:83,358,116...83,382,326
JBrowse link
G Rab34 RAB34, member RAS oncogene family ISO
IBA
ISS
(MGI:MGI:5467668|PMID:23197834)
PMID:21873635
GO_REF:0000024
(PMID:21255211)
RGD
UniProt
PMID:21255211, PMID:23197834, PMID:21873635 GO_REF:0000024, MGI:MGI:5467668, RGD:13792537 NCBI chr10:65,448,111...65,452,178
Ensembl chr10:65,448,950...65,452,177
JBrowse link
G Rab39a RAB39A, member RAS oncogene family ISO (PMID:21255211) RGD PMID:21255211 NCBI chr 8:58,275,984...58,292,995
Ensembl chr 8:58,272,098...58,293,102
JBrowse link
G Rab7a RAB7A, member RAS oncogene family ISO
IBA
ISS
(PMID:21255211)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:21255211, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173
JBrowse link
G Rab7b Rab7b, member RAS oncogene family IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:48,456,143...48,483,714
Ensembl chr13:48,455,923...48,482,138
JBrowse link
G Syt7 synaptotagmin 7 ISO
ISS
(MGI:MGI:3690533|PMID:16982801)
GO_REF:0000024
RGD
UniProt
PMID:16982801 GO_REF:0000024, MGI:MGI:3690533 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377
JBrowse link
G Tmem175 transmembrane protein 175 ISO
ISS
(MGI:MGI:5693670|PMID:26317472)
GO_REF:0000024
RGD
UniProt
PMID:26317472 GO_REF:0000024, MGI:MGI:5693670 NCBI chr14:2,083,745...2,100,006
Ensembl chr14:2,083,712...2,100,005
JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spg11 SPG11 vesicle trafficking associated, spatacsin ISO MGI:MGI:4377985 (MGI:MGI:5749311|PMID:26284655) RGD PMID:26284655 MGI:MGI:5749311 NCBI chr 3:113,999,600...114,064,438
Ensembl chr 3:113,999,719...114,065,170
JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa8 heat shock protein family A (Hsp70) member 8 IMP RGD PMID:9038169 RGD:10059368 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Mt3 metallothionein 3 ISO
ISS
(MGI:MGI:4881636|PMID:20544854)
GO_REF:0000024
RGD
UniProt
PMID:20544854 GO_REF:0000024, MGI:MGI:4881636 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:28073925)
(MGI:MGI:5905514|PMID:28073925)
UniProt
Ensembl
RGD
PMID:28073925 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5905514 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC681325 hypothetical protein LOC681325 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:80,359,555...80,363,168
Ensembl chr  X:80,359,555...80,363,168
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO (PMID:22012985) RGD PMID:22012985 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 ISO
IBA
(PMID:31001245)
PMID:21873635
RGD PMID:31001245, PMID:21873635 RGD:13792537 NCBI chr  X:54,390,733...54,409,466
Ensembl chr  X:54,390,733...54,409,466
JBrowse link
G Tmem165 transmembrane protein 165 ISO
ISS
(PMID:23569283)
GO_REF:0000024
RGD
UniProt
PMID:23569283 GO_REF:0000024 NCBI chr14:34,503,037...34,528,262
Ensembl chr14:34,503,038...34,528,262
JBrowse link
G Tmem175 transmembrane protein 175 ISO
ISS
(MGI:MGI:5693670|PMID:26317472)
GO_REF:0000024
RGD
UniProt
PMID:26317472 GO_REF:0000024, MGI:MGI:5693670 NCBI chr14:2,083,745...2,100,006
Ensembl chr14:2,083,712...2,100,005
JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes ISO
ISS
(PMID:28013294)
GO_REF:0000024
RGD
UniProt
PMID:28013294 GO_REF:0000024 NCBI chr12:38,459,816...38,482,903
Ensembl chr12:38,459,832...38,484,512
JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal protein transmembrane 4 beta ISO
ISS
(PMID:26280656)
GO_REF:0000024
RGD
UniProt
PMID:26280656 GO_REF:0000024 NCBI chr 7:72,924,911...72,968,099
Ensembl chr 7:72,924,799...72,968,101
JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal protein transmembrane 4 beta ISO
ISS
(PMID:26280656)
GO_REF:0000024
RGD
UniProt
PMID:26280656 GO_REF:0000024 NCBI chr 7:72,924,911...72,968,099
Ensembl chr 7:72,924,799...72,968,101
JBrowse link
G Trex1 three prime repair exonuclease 1 ISO MGI:MGI:3052754 (MGI:MGI:5460923|PMID:23160154) RGD PMID:23160154 MGI:MGI:5460923 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      cellular component organization or biogenesis 6766
        cellular component organization 6510
          organelle organization 4073
            vacuole organization 197
              lytic vacuole organization 77
                lysosome organization + 77
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.