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ONTOLOGY REPORT - ANNOTATIONS


Term:membrane repolarization during cardiac muscle cell action potential
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Accession:GO:0086013 term browser browse the term
Definition:The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.


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membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO (PMID:8900283)
(PMID:10400998)
BHF-UCL PMID:8900283, PMID:10400998 NCBI chr31:29,858,428...29,868,315 JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 ISO (PMID:21536673) BHF-UCL PMID:21536673 NCBI chr16:15,009,031...15,041,786
Ensembl chr16:15,009,031...15,041,504
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 IEA Ensembl GO_REF:0000107 NCBI chr 9:16,468,938...16,475,722
Ensembl chr 9:16,468,938...16,475,722
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO (PMID:8528244) BHF-UCL PMID:8528244 NCBI chr18:46,554,390...46,830,533
Ensembl chr18:46,518,908...46,830,043
JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 IEA Ensembl GO_REF:0000107 NCBI chr27:39,808,987...39,810,789
Ensembl chr27:39,756,363...39,811,035
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 IEA Ensembl GO_REF:0000107 NCBI chr 5:5,736,544...5,760,705
Ensembl chr 5:5,740,176...5,760,866
JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 ISO (MGI:MGI:5292192|PMID:19139040) BHF-UCL PMID:19139040 MGI:MGI:5292192 NCBI chr11:4,279,362...4,423,080
Ensembl chr11:4,154,746...4,423,078
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 IEA Ensembl GO_REF:0000107 NCBI chr18:46,554,390...46,830,533
Ensembl chr18:46,518,908...46,830,043
JBrowse link
membrane repolarization during bundle of His cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 IEA Ensembl GO_REF:0000107 NCBI chr27:39,808,987...39,810,789
Ensembl chr27:39,756,363...39,811,035
JBrowse link
membrane repolarization during SA node cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 IEA Ensembl GO_REF:0000107 NCBI chr27:39,808,987...39,810,789
Ensembl chr27:39,756,363...39,811,035
JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCND3 potassium voltage-gated channel subfamily D member 3 IEA GOC GO_REF:0000108 NCBI chr17:63,470,829...63,668,354
Ensembl chr17:63,470,415...63,668,035
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 IEA GOC GO_REF:0000108 NCBI chr31:29,858,428...29,868,315 JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 IEA Ensembl GO_REF:0000107 NCBI chr31:29,777,154...29,777,839
Ensembl chr31:29,581,658...29,777,525
JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 IEA GOC GO_REF:0000108 NCBI chr21:23,860,727...23,872,194
Ensembl chr21:23,871,648...23,871,947
JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 IEA GOC GO_REF:0000108 NCBI chr37:28,994,797...28,998,596
Ensembl chr37:28,996,105...28,996,990
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 IEA GOC GO_REF:0000108 NCBI chr  X:82,844,188...82,845,641
Ensembl chr  X:82,845,064...82,846,083
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 IEA Ensembl GO_REF:0000107 NCBI chr16:15,009,031...15,041,786
Ensembl chr16:15,009,031...15,041,504
JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 IEA Ensembl GO_REF:0000107 NCBI chr27:25,368,565...25,375,754
Ensembl chr27:25,368,810...25,375,009
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr18:46,554,390...46,830,533
Ensembl chr18:46,518,908...46,830,043
JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 IEA Ensembl GO_REF:0000107 NCBI chr21:23,860,727...23,872,194
Ensembl chr21:23,871,648...23,871,947
JBrowse link
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF207 ring finger protein 207 IEA Ensembl GO_REF:0000107 NCBI chr 5:60,105,200...60,119,902
Ensembl chr 5:60,106,297...60,118,670
JBrowse link
regulation of membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLNA filamin A ISO (MGI:MGI:5578267|PMID:24951510) BHF-UCL PMID:24951510 MGI:MGI:5578267 NCBI chr  X:122,058,303...122,083,467
Ensembl chr  X:122,061,455...122,083,203
JBrowse link
regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLG1 discs large MAGUK scaffold protein 1 IEA Ensembl GO_REF:0000107 NCBI chr33:30,016,323...30,253,180
Ensembl chr33:30,016,600...30,253,547
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16162
    localization 5962
      establishment of localization 4476
        establishment of localization in cell 2054
          cardiac muscle cell membrane repolarization 31
            membrane repolarization during cardiac muscle cell action potential 16
              membrane repolarization during AV node cell action potential 0
              membrane repolarization during Purkinje myocyte action potential 0
              membrane repolarization during SA node cell action potential 1
              membrane repolarization during atrial cardiac muscle cell action potential + 4
              membrane repolarization during bundle of His cell action potential 1
              membrane repolarization during ventricular cardiac muscle cell action potential + 11
              negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
              positive regulation of membrane repolarization during cardiac muscle cell action potential + 1
              regulation of membrane repolarization during cardiac muscle cell action potential + 4
Path 2
Term Annotations click to browse term
  biological_process 16162
    localization 5962
      establishment of localization 4476
        transport 4334
          ion transport 1691
            ion transmembrane transport 1151
              membrane repolarization 43
                cardiac muscle cell membrane repolarization 31
                  membrane repolarization during cardiac muscle cell action potential 16
                    membrane repolarization during AV node cell action potential 0
                    membrane repolarization during Purkinje myocyte action potential 0
                    membrane repolarization during SA node cell action potential 1
                    membrane repolarization during atrial cardiac muscle cell action potential + 4
                    membrane repolarization during bundle of His cell action potential 1
                    membrane repolarization during ventricular cardiac muscle cell action potential + 11
                    negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
                    positive regulation of membrane repolarization during cardiac muscle cell action potential + 1
                    regulation of membrane repolarization during cardiac muscle cell action potential + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.