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ONTOLOGY REPORT - ANNOTATIONS


Term:membrane repolarization during cardiac muscle cell action potential
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Accession:GO:0086013 term browser browse the term
Definition:The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.


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membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO (PMID:10400998)
(PMID:8900283)
BHF-UCL PMID:8900283, PMID:10400998 NCBI chr13:198,051,281...198,059,444 JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 ISO (PMID:21536673) BHF-UCL PMID:21536673 NCBI chr18:6,242,826...6,279,154
Ensembl chr18:6,243,524...6,279,111
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 IEA Ensembl GO_REF:0000107 NCBI chr12:10,351,959...10,380,631
Ensembl chr12:10,349,409...10,362,244
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO (PMID:8528244) BHF-UCL PMID:8528244 NCBI chr 2:1,675,323...1,989,110
Ensembl chr 2:1,675,360...1,989,111
JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045, PMID:23264583 NCBI chr 5:65,439,336...65,442,207 JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 IEA Ensembl GO_REF:0000107 NCBI chr 9:55,836,777...55,861,288
Ensembl chr 9:55,836,701...55,864,941
JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 ISO (MGI:MGI:5292192|PMID:19139040) BHF-UCL PMID:19139040 MGI:MGI:5292192 NCBI chr 2:118,439,328...118,882,299
Ensembl chr 2:118,439,403...118,882,296
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:1,675,323...1,989,110
Ensembl chr 2:1,675,360...1,989,111
JBrowse link
membrane repolarization during bundle of His cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO (PMID:23264583) BHF-UCL PMID:23264583 NCBI chr 5:65,439,336...65,442,207 JBrowse link
membrane repolarization during SA node cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO (PMID:19343045) BHF-UCL PMID:19343045 NCBI chr 5:65,439,336...65,442,207 JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCND3 potassium voltage-gated channel subfamily D member 3 IEA GOC GO_REF:0000108 NCBI chr 4:108,394,687...108,621,514
Ensembl chr 4:108,401,895...108,621,509
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 IEA GOC GO_REF:0000108 NCBI chr13:198,051,281...198,059,444 JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO (PMID:10219239) BHF-UCL PMID:10219239 NCBI chr13:197,979,749...197,980,974 JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 IEA GOC GO_REF:0000108 NCBI chr 9:8,810,716...8,822,191
Ensembl chr 9:8,810,722...8,821,817
JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 IEA GOC GO_REF:0000108 NCBI chr15:124,910,708...124,915,787
Ensembl chr15:124,912,405...124,915,780
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 IEA GOC GO_REF:0000108 NCBI chr  X:89,741,187...89,742,732
Ensembl chr  X:89,742,113...89,742,550
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 IEA Ensembl GO_REF:0000107 NCBI chr18:6,242,826...6,279,154
Ensembl chr18:6,243,524...6,279,111
JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 IEA Ensembl GO_REF:0000107 NCBI chr 5:51,695,927...51,704,402
Ensembl chr 5:51,537,774...51,703,817
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 2:1,675,323...1,989,110
Ensembl chr 2:1,675,360...1,989,111
JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 IEA Ensembl GO_REF:0000107 NCBI chr 9:8,810,716...8,822,191
Ensembl chr 9:8,810,722...8,821,817
JBrowse link
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF207 ring finger protein 207 IEA Ensembl GO_REF:0000107 NCBI chr 6:67,105,347...67,119,167
Ensembl chr 6:67,105,763...67,116,510
JBrowse link
regulation of membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLNA filamin A ISO (MGI:MGI:5578267|PMID:24951510) BHF-UCL PMID:24951510 MGI:MGI:5578267 NCBI chr  X:124,889,934...124,915,000
Ensembl chr  X:124,890,142...124,917,171
JBrowse link
regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLG1 discs large MAGUK scaffold protein 1 IEA Ensembl GO_REF:0000107 NCBI chr13:132,819,931...133,084,880
Ensembl chr13:132,820,870...133,086,843
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    localization 5918
      establishment of localization 4437
        establishment of localization in cell 2023
          cardiac muscle cell membrane repolarization 31
            membrane repolarization during cardiac muscle cell action potential 16
              membrane repolarization during AV node cell action potential 0
              membrane repolarization during Purkinje myocyte action potential 0
              membrane repolarization during SA node cell action potential 1
              membrane repolarization during atrial cardiac muscle cell action potential + 4
              membrane repolarization during bundle of His cell action potential 1
              membrane repolarization during ventricular cardiac muscle cell action potential + 11
              negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
              positive regulation of membrane repolarization during cardiac muscle cell action potential + 1
              regulation of membrane repolarization during cardiac muscle cell action potential + 4
Path 2
Term Annotations click to browse term
  biological_process 16524
    localization 5918
      establishment of localization 4437
        transport 4296
          ion transport 1674
            ion transmembrane transport 1124
              membrane repolarization 43
                cardiac muscle cell membrane repolarization 31
                  membrane repolarization during cardiac muscle cell action potential 16
                    membrane repolarization during AV node cell action potential 0
                    membrane repolarization during Purkinje myocyte action potential 0
                    membrane repolarization during SA node cell action potential 1
                    membrane repolarization during atrial cardiac muscle cell action potential + 4
                    membrane repolarization during bundle of His cell action potential 1
                    membrane repolarization during ventricular cardiac muscle cell action potential + 11
                    negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
                    positive regulation of membrane repolarization during cardiac muscle cell action potential + 1
                    regulation of membrane repolarization during cardiac muscle cell action potential + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.