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ONTOLOGY REPORT - ANNOTATIONS


Term:membrane repolarization during cardiac muscle cell action potential
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Accession:GO:0086013 term browser browse the term
Definition:The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.


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membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO (PMID:10400998), (PMID:8900283) RGD PMID:8900283, PMID:10400998 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 ISO (PMID:21536673) RGD PMID:21536673 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 ISO (PMID:11371347) RGD PMID:11371347 NCBI chr10:99,429,337...99,442,520
Ensembl chr10:99,437,436...99,439,114
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 ISO (PMID:8528244) RGD PMID:8528244 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel subfamily A member 5 ISO (PMID:19343045), (PMID:23264583) RGD PMID:19343045, PMID:23264583 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 ISO (PMID:20560207) RGD PMID:20560207 NCBI chr 8:33,435,493...33,463,410
Ensembl chr 8:33,433,905...33,463,467
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 ISO (MGI:MGI:5292192|PMID:19139040) RGD PMID:19139040 MGI:MGI:5292192 NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IEA
ISO
GO_REF:0000107
(PMID:12522251), (PMID:25786344)
Ensembl
RGD
PMID:12522251, PMID:25786344 GO_REF:0000107 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
membrane repolarization during bundle of His cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel subfamily A member 5 ISO (PMID:23264583) RGD PMID:23264583 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
membrane repolarization during SA node cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna5 potassium voltage-gated channel subfamily A member 5 ISO (PMID:19343045) RGD PMID:19343045 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnd3 potassium voltage-gated channel subfamily D member 3 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:207,923,775...208,140,727
Ensembl chr 2:207,923,775...208,140,727
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO (PMID:9354802) RGD PMID:9354802 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO (PMID:10219239) RGD PMID:10219239 NCBI chr11:32,434,786...32,447,264
Ensembl chr11:32,440,237...32,447,259
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:165,189,934...165,196,949
Ensembl chr 1:165,189,985...165,196,948
JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:84,688,873...84,693,066
Ensembl chr 9:84,689,150...84,690,338
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:113,583,844...113,584,459
Ensembl chr  X:113,583,844...113,584,459
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 ISO
IEA
(PMID:21536673)
GO_REF:0000107
RGD
Ensembl
PMID:21536673 GO_REF:0000107 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 ISO (PMID:20558321) RGD PMID:20558321 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 ISO
IBA
IEA
(PMID:8528244)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:8528244, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 ISO (PMID:22987075) RGD PMID:22987075 NCBI chr 1:165,189,934...165,196,949
Ensembl chr 1:165,189,985...165,196,948
JBrowse link
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf207 ring finger protein 207 ISO (PMID:25281747) RGD PMID:25281747 NCBI chr 5:169,486,253...169,500,451
Ensembl chr 5:169,486,257...169,499,268
JBrowse link
regulation of membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flna filamin A ISO (MGI:MGI:5578267|PMID:24951510) RGD PMID:24951510 MGI:MGI:5578267 NCBI chr  X:156,460,785...156,487,245
Ensembl chr  X:156,463,953...156,487,245
JBrowse link
regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlg1 discs large MAGUK scaffold protein 1 IEA
ISO
GO_REF:0000107
(MGI:MGI:5816439|PMID:25447080)
Ensembl
RGD
PMID:25447080 GO_REF:0000107, MGI:MGI:5816439 NCBI chr11:72,164,566...72,378,895
Ensembl chr11:72,163,749...72,378,895
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    localization 6486
      establishment of localization 4918
        establishment of localization in cell 2156
          cardiac muscle cell membrane repolarization 31
            membrane repolarization during cardiac muscle cell action potential 16
              membrane repolarization during AV node cell action potential 0
              membrane repolarization during Purkinje myocyte action potential 0
              membrane repolarization during SA node cell action potential 1
              membrane repolarization during atrial cardiac muscle cell action potential + 4
              membrane repolarization during bundle of His cell action potential 1
              membrane repolarization during ventricular cardiac muscle cell action potential + 11
              negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
              positive regulation of membrane repolarization during cardiac muscle cell action potential + 1
              regulation of membrane repolarization during cardiac muscle cell action potential + 4
Path 2
Term Annotations click to browse term
  biological_process 20014
    localization 6486
      establishment of localization 4918
        transport 4774
          ion transport 1783
            ion transmembrane transport 1189
              membrane repolarization 43
                cardiac muscle cell membrane repolarization 31
                  membrane repolarization during cardiac muscle cell action potential 16
                    membrane repolarization during AV node cell action potential 0
                    membrane repolarization during Purkinje myocyte action potential 0
                    membrane repolarization during SA node cell action potential 1
                    membrane repolarization during atrial cardiac muscle cell action potential + 4
                    membrane repolarization during bundle of His cell action potential 1
                    membrane repolarization during ventricular cardiac muscle cell action potential + 11
                    negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
                    positive regulation of membrane repolarization during cardiac muscle cell action potential + 1
                    regulation of membrane repolarization during cardiac muscle cell action potential + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.