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ONTOLOGY REPORT - ANNOTATIONS


Term:membrane repolarization during cardiac muscle cell action potential
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Accession:GO:0086013 term browser browse the term
Definition:The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.


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membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO (PMID:8900283)
(PMID:10400998)
BHF-UCL PMID:8900283, PMID:10400998 NCBI chrNW_004936500:7,998,464...8,007,848 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 ISO (PMID:21536673) BHF-UCL PMID:21536673 NCBI chrNW_004936527:6,380,222...6,412,390 JBrowse link
G Kcnj2 potassium inwardly rectifying channel subfamily J member 2 ISO (PMID:11371347) BHF-UCL PMID:11371347 NCBI chrNW_004936655:3,447,026...3,459,569 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 ISO (PMID:8528244) BHF-UCL PMID:8528244 NCBI chrNW_004936794:707,122...994,206 JBrowse link
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnj5 potassium inwardly rectifying channel subfamily J member 5 ISO (PMID:20560207) BHF-UCL PMID:20560207 NCBI chrNW_004936572:3,344,942...3,373,690 JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 ISO (MGI:MGI:5292192|PMID:19139040) BHF-UCL PMID:19139040 MGI:MGI:5292192 NCBI chrNW_004937043:133,981...269,593 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 ISO (PMID:12522251), (PMID:25786344) BHF-UCL PMID:12522251, PMID:25786344 NCBI chrNW_004936794:707,122...994,206 JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO (PMID:9354802) BHF-UCL PMID:9354802 NCBI chrNW_004936500:7,998,464...8,007,848 JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO (PMID:10219239) BHF-UCL PMID:10219239 NCBI chrNW_004936500:8,067,009...8,072,383 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 ISO (PMID:21536673) BHF-UCL PMID:21536673 NCBI chrNW_004936527:6,380,222...6,412,390 JBrowse link
G Kcnj8 potassium inwardly rectifying channel subfamily J member 8 ISO (PMID:20558321) BHF-UCL PMID:20558321 NCBI chrNW_004936548:5,125,583...5,132,490 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 ISO (PMID:8528244) BHF-UCL PMID:8528244 NCBI chrNW_004936794:707,122...994,206 JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 ISO (PMID:22987075) BHF-UCL PMID:22987075 NCBI chrNW_004936498:3,477,313...3,487,580 JBrowse link
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf207 ring finger protein 207 ISO (PMID:25281747) BHF-UCL PMID:25281747 NCBI chrNW_004936623:1,065,260...1,079,918 JBrowse link
regulation of membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flna filamin A ISO (MGI:MGI:5578267|PMID:24951510) BHF-UCL PMID:24951510 MGI:MGI:5578267 NCBI chrNW_004936809:1,097,288...1,123,206 JBrowse link
regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlg1 discs large MAGUK scaffold protein 1 ISO (MGI:MGI:5816439|PMID:25447080) BHF-UCL PMID:25447080 MGI:MGI:5816439 NCBI chrNW_004936833:551,989...843,064 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    localization 4764
      establishment of localization 3429
        establishment of localization in cell 1628
          cardiac muscle cell membrane repolarization 27
            membrane repolarization during cardiac muscle cell action potential 12
              membrane repolarization during AV node cell action potential 0
              membrane repolarization during Purkinje myocyte action potential 0
              membrane repolarization during SA node cell action potential 0
              membrane repolarization during atrial cardiac muscle cell action potential + 3
              membrane repolarization during bundle of His cell action potential 0
              membrane repolarization during ventricular cardiac muscle cell action potential + 8
              negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
              positive regulation of membrane repolarization during cardiac muscle cell action potential + 1
              regulation of membrane repolarization during cardiac muscle cell action potential + 4
Path 2
Term Annotations click to browse term
  biological_process 11962
    localization 4764
      establishment of localization 3429
        transport 3284
          ion transport 1228
            ion transmembrane transport 683
              membrane repolarization 39
                cardiac muscle cell membrane repolarization 27
                  membrane repolarization during cardiac muscle cell action potential 12
                    membrane repolarization during AV node cell action potential 0
                    membrane repolarization during Purkinje myocyte action potential 0
                    membrane repolarization during SA node cell action potential 0
                    membrane repolarization during atrial cardiac muscle cell action potential + 3
                    membrane repolarization during bundle of His cell action potential 0
                    membrane repolarization during ventricular cardiac muscle cell action potential + 8
                    negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
                    positive regulation of membrane repolarization during cardiac muscle cell action potential + 1
                    regulation of membrane repolarization during cardiac muscle cell action potential + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.