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ONTOLOGY REPORT - ANNOTATIONS


Term:AV node cell action potential
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Accession:GO:0086016 term browser browse the term
Definition:An action potential that occurs in an atrioventricular node cardiac muscle cell.
Synonyms:exact_synonym: AV node cardiac muscle cell action potential;   atrioventricular node cardiac muscle cell action potential


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AV node cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1g calcium voltage-gated channel subunit alpha1 G ISO
ISS
(MGI:MGI:3714901|PMID:16690884)
GO_REF:0000024
RGD
BHF-UCL
PMID:16690884 GO_REF:0000024, MGI:MGI:3714901 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 ISO (PMID:24998131) RGD PMID:24998131 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 ISO (PMID:17592081) RGD PMID:17592081 NCBI chr 8:49,441,106...49,456,279
Ensembl chr 8:49,441,106...49,456,279
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO
IBA
ISS
(PMID:18616619)
PMID:21873635
GO_REF:0000024
RGD
BHF-UCL
PMID:18616619, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
membrane depolarization during AV node cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO
ISS
IEA
(PMID:26253506)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:26253506 GO_REF:0000024, GO_REF:0000107 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G ISO
ISS
IEA
(MGI:MGI:3714901|PMID:16690884)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:16690884 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3714901 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 ISO
ISS
IEA
(PMID:17224476)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:17224476 GO_REF:0000024, GO_REF:0000107 NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO
IEA
ISS
(PMID:18616619)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
BHF-UCL
PMID:18616619 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IEA
ISO
GO_REF:0000107
(PMID:27207958)
Ensembl
RGD
PMID:27207958 GO_REF:0000107 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
regulation of AV node cell action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 ISO (MGI:MGI:2449848|PMID:12571597) RGD PMID:12571597 MGI:MGI:2449848 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule ISO (MGI:MGI:3814765|PMID:18636119) RGD PMID:18636119 MGI:MGI:3814765 NCBI chr11:16,826,269...16,873,564
Ensembl chr11:16,826,399...16,873,562
JBrowse link
G Gja5 gap junction protein, alpha 5 ISO (PMID:22247482)
(MGI:MGI:3696497|PMID:10515563)
RGD PMID:10515563, PMID:22247482 MGI:MGI:3696497 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Ryr2 ryanodine receptor 2 ISO
IEA
(PMID:17875969)
GO_REF:0000107
RGD
Ensembl
PMID:17875969 GO_REF:0000107 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    signaling 7588
      cell-cell signaling 1752
        cell-cell signaling involved in cardiac conduction 25
          AV node cell to bundle of His cell signaling 11
            AV node cell action potential 11
              membrane depolarization during AV node cell action potential + 5
              membrane repolarization during AV node cell action potential 0
              negative regulation of AV node cell action potential + 0
              positive regulation of AV node cell action potential + 0
              regulation of AV node cell action potential + 4
Path 2
Term Annotations click to browse term
  biological_process 20014
    multicellular organismal process 9055
      system process 3445
        circulatory system process 578
          blood circulation 550
            heart contraction 246
              regulation of heart contraction 200
                cardiac conduction 66
                  cell communication involved in cardiac conduction 41
                    AV node cell to bundle of His cell communication 13
                      AV node cell to bundle of His cell signaling 11
                        AV node cell action potential 11
                          membrane depolarization during AV node cell action potential + 5
                          membrane repolarization during AV node cell action potential 0
                          negative regulation of AV node cell action potential + 0
                          positive regulation of AV node cell action potential + 0
                          regulation of AV node cell action potential + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.